The Effect of Maternal Diet and Lifestyle on the Risk of Childhood Obesity.

Łuszczki, Edyta; Wyszyńska, Justyna; Dymek, Agnieszka; Drożdż, Dorota; González-Ramos, Laura; Hartgring, Isa; García-Carbonell, Nuria; Mazur, Artur; Erdine, Serap; Parnarauskienė, Justė; Alvarez-Pitti, Julio

Background/Objectives: Childhood obesity is a global health problem that affects at least 41 million children under the age of five. Increased BMI in children is associated with serious long-term health consequences, such as type 2 diabetes, cardiovascular disease, and psychological problems, including depression and low self-esteem. Although the etiology of obesity is complex, research suggests that the diet and lifestyle of pregnant women play a key role in shaping metabolic and epigenetic changes that can increase the risk of obesity in their children. Excessive gestational weight gain, unhealthy dietary patterns (including the Western diet), and pregnancy complications (such as gestational diabetes) are some of the modifiable factors that contribute to childhood obesity. The purpose of this narrative review is to summarize the most important and recent information on the impact of the diet and lifestyle of pregnant women on the risk of childhood obesity. Methods: This article is a narrative review that aims to summarize the available literature on the impact of pregnant women's diet and lifestyle on the risk of obesity in their offspring, with a focus on metabolic and epigenetic mechanisms. Results/Conclusions: Current evidence suggests that a pregnant woman's lifestyle and diet can significantly contribute to lowering the risk of obesity in their offspring. However, further high-quality research is needed to understand better the metabolic and epigenetic relationships concerning maternal factors that predispose offspring to obesity.

DIETARY patterns; WESTERN diet; TYPE 2 diabetes; PREGNANCY complications; PREGNANT women; CHILDHOOD obesity; WEIGHT gain; GESTATIONAL diabetes

Metabolites (2218-1989), 2024, Vol 14, Issue 12, p655

2218-1989

Academic Journal

10.3390/metabo14120655