Works matching DE "CYTOCHROME P-450 CYP2D6"

Results: 508

Pharmacogenetics and therapeutic drug monitoring of fluoxetine in a real-world setting: A PK/PD analysis of the influence of (non-)genetic factors.

Published in:

2020

By:

Magalhães, Paulo;
Alves, Gilberto;
Fortuna, Ana;
Llerena, Adrián;
Falcão, Amílcar;
Clinical Collaborators of the GnG-PK/PD-AD Study

Publication type:

Journal Article

Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients.

Published in:

British Journal of Clinical Pharmacology, 2025, v. 91, n. 6, p. 1842, doi. 10.1111/bcp.70004

By:

Sarömba, Jens Andreas;
Müller, Julian Peter;
Tupiec, Jolanta;
Roeth, Anjali;
Kurt, Berkan;
Kahles, Florian;
Laurentius, Thea;
Bollheimer, Cornelius;
Stingl, Julia C.;
Just, Katja S.

Publication type:

Article

Metabolic ratios and SNPs implicated in tramadol-related deaths.

Published in:

International Journal of Legal Medicine, 2023, v. 137, n. 5, p. 1431, doi. 10.1007/s00414-023-03052-8

By:

Aly, Sanaa M.;
Hakim, Florian;
Richeval, Camille;
Hennart, Benjamin;
Gaulier, Jean-michel;
Allorge, Delphine

Publication type:

Article

Exploring the 1000 Genomes Project haplotype reporting for the CYP2D6 pharmacogene.

Published in:

2019

By:

Wendt, Frank R.;
Woerner, August E.;
Sajantila, Antti;
Moura-Neto, Rodrigo S.;
Budowle, Bruce

Publication type:

Letter to the Editor

Full-gene haplotypes refine CYP2D6 metabolizer phenotype inferences.

Published in:

International Journal of Legal Medicine, 2018, v. 132, n. 4, p. 1007, doi. 10.1007/s00414-017-1709-0

By:

Wendt, Frank R.;
Woerner, August E.;
Budowle, Bruce;
Sajantila, Antti;
Moura-Neto, Rodrigo S.

Publication type:

Article

The relationship of postoperative tramadol activity with the CYP2D6*17 genome in total knee artroplasty patients.

Published in:

Pamukkale Medical Journal, 2024, v. 17, n. 2, p. 237, doi. 10.31362/patd.1351539

By:

Ök, Nusret;
Gürbüz, Muhammed Erdi;
Köseler, Aylin

Publication type:

Article

Drug metabolizing enzymes-associated chemo resistance and strategies to overcome it.

Published in:

Drug Metabolism Reviews, 2019, v. 51, n. 2, p. 196, doi. 10.1080/03602532.2019.1632886

By:

Verma, Himanshu;
Singh Bahia, Malkeet;
Choudhary, Shalki;
Kumar Singh, Pankaj;
Silakari, Om

Publication type:

Article

valuation of the inhibition performance of pyrrole derivatives against CYP450 isoforms.

Published in:

Pharmacia (0428-0296), 2024, v. 71, n. 1, p. 1, doi. 10.3897/pharmacia.71.e122067

By:

Kondeva-Burdina, Magdalena;
Mateev, Emilio;
Irfan, Ali;
Kuteva, Hristina;
Georgieva, Maya

Publication type:

Article

Association Between CYP2D6 Genotypes and Serum Concentrations of Mirtazapine and Mianserin.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2025, v. 136, n. 4, p. 1, doi. 10.1111/bcpt.70013

By:

Hole, Kristine;
Molden, Espen

Publication type:

Article

Pharmacogenetic testing of CYP2D6, CYP2C19 and CYP2C9 in Denmark: Agreement between publicly funded genotyping tests and the subsequent phenotype classification.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 5, p. 756, doi. 10.1111/bcpt.13990

By:

Houlind, Morten Baltzer;
Hansen, Luise;
Iversen, Esben;
Rasmussen, Henrik Berg;
Larsen, Jens Borggaard;
Jørgensen, Steffen;
Dalhoff, Kim;
Damkier, Per;
Walls, Anne B.;
Vermehren, Charlotte;
Andersen, Trine Rune Høgh;
Kallemose, Thomas;
Christrup, Lona;
Westergaard, Niels

Publication type:

Article

Effect of CYP2D6 genotype on duloxetine serum concentration.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 1, p. 186, doi. 10.1111/bcpt.13954

By:

Hole, Kristine;
Gangsø, Sofie;
Jensstuen, Åsa Tonette;
Ormøy, Hanne Holte;
Paulsen, Maren;
Molden, Espen;
Haslemo, Tore

Publication type:

Article

Using population pharmacokinetic analyses of drugs metabolized by CYP2D6 to study the genotype–phenotype translation.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 2, p. 113, doi. 10.1111/bcpt.13903

By:

Frederiksen, Trine

Publication type:

Article

Drug metabolism and drug transport of the 100 most prescribed oral drugs.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2022, v. 131, n. 5, p. 311, doi. 10.1111/bcpt.13780

By:

Iversen, Ditte B.;
Andersen, Nanna Elman;
Dalgård Dunvald, Ann‐Cathrine;
Pottegård, Anton;
Stage, Tore B.

Publication type:

Article

Post‐marketing assessment of generic tamoxifen in Brazilian breast cancer patients.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 126, n. 5, p. 432, doi. 10.1111/bcpt.13368

By:

Ximenez, João P.;
Lanchote, Vera L.;
Bello, Marcelo A.;
Iocken, Fernanda H. S.;
Obadia, Renata C. M.;
Sousa, Valéria P.;
Suarez‐Kurtz, Guilherme

Publication type:

Article

Impact of Ageing on Serum Concentrations of Risperidone and Its Active Metabolite in Patients with Known CYP2D6 Genotype.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2016, v. 119, n. 5, p. 470, doi. 10.1111/bcpt.12614

By:

Molden, Espen;
Waade, Ragnhild Birkeland;
Hoff, Maren;
Haslemo, Tore

Publication type:

Article

High Frequency of CYP2D6 Ultrarapid Metabolizer Genotype in the Finnish Population.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2016, v. 119, n. 3, p. 291, doi. 10.1111/bcpt.12590

By:

Pietarinen, Paavo;
Tornio, Aleksi;
Niemi, Mikko

Publication type:

Article

Polymorphisms in CYP2D6 have a Greater Effect on Variability of Risperidone Pharmacokinetics than Gender.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2015, v. 116, n. 2, p. 124, doi. 10.1111/bcpt.12286

By:

Cabaleiro, Teresa;
Ochoa, Dolores;
Román, Manuel;
Moreno, Isabel;
López‐Rodríguez, Rosario;
Novalbos, Jesús;
Abad‐Santos, Francisco

Publication type:

Article

CYP2 D6-Inhibiting Drugs and the Increased Risk of Fall-Related Injuries Due to Newly Initiated Opioid Treatment - A Swedish, Register-Based Case-Crossover Study.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2015, v. 116, n. 2, p. 134, doi. 10.1111/bcpt.12289

By:

Möller, Jette;
Laflamme, Lucie;
Söderberg Löfdal, Karin

Publication type:

Article

Incidence of inactive allele CYP2D6*4 among Greek women suffering from hormone-sensitive breast cancer.

Published in:

European Journal of Gynaecological Oncology, 2016, v. 37, n. 4, p. 504, doi. 10.12892/ejgo3051.2016

By:

Kykalos, S.;
Mantas, D.;
Charalampoudis, P.;
Kouraklis, G.;
Markopoulos, C.

Publication type:

Article

The impact of CYP2D6 on donepezil concentration and its lack of effect on the treatment response and adverse effect in Korean patients with Alzheimer's disease.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 2, p. 227, doi. 10.4196/kjpp.24.239

By:

Tae-Eun Kim;
Jung-Woo Bae;
Seongkuk Hong;
Hong Jun Jeon;
Yeonsil Moon

Publication type:

Article

Bupropion Increased More than Five Times the Systemic Exposure to Aripiprazole: An In Vivo Study in Wistar albino Rats.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 11, p. 588, doi. 10.3390/metabo14110588

By:

Ciocotișan, Iulia-Maria;
Muntean, Dana Maria;
Vlase, Laurian

Publication type:

Article

The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The Challenge of Forensic Toxicogenetics.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 5, p. 661, doi. 10.3390/metabo13050661

By:

Giorgetti, Arianna;
Amurri, Sara;
Fazio, Giulia;
Bini, Carla;
Anniballi, Laura;
Pirani, Filippo;
Pelletti, Guido;
Pelotti, Susi

Publication type:

Article

Optimising Fluvoxamine Maternal/Fetal Exposure during Gestation: A Pharmacokinetic Virtual Clinical Trials Study.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 12, p. 1281, doi. 10.3390/metabo12121281

By:

Burhanuddin, Khairulanwar;
Badhan, Raj

Publication type:

Article

Categorization of Cytochrome P4502D6 Activity Score by Urinary Amphetamine/Methamphetamine Ratios.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 12, p. 1174, doi. 10.3390/metabo12121174

By:

Chaichana, Jatuporn;
Khamenkhetkarn, Manee;
Sastraruji, Thanapat;
Monum, Tawachai;
O'Brien, Timothy E.;
Amornlertwatana, Yutti;
Jaikang, Churdsak

Publication type:

Article

PKM2–c-Myc–Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.550469

By:

Yu, Pian;
Li, Ao-xue;
Chen, Xi-sha;
Tian, Min;
Wang, Hai-yan;
Wang, Xin-luan;
Zhang, Yi;
Wang, Kuan-song;
Cheng, Yan

Publication type:

Article

Polymorphisms of Drug-Metabolizing Enzymes and Transporters Contribute to the Individual Variations of Erlotinib Steady State Trough Concentration, Treatment Outcomes, and Adverse Reactions in Epidermal Growth Factor Receptor–Mutated Non-Small Cell Lung Cancer Patients

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00664

By:

Liao, Dehua;
Liu, Zhigang;
Zhang, Yongchang;
Liu, Ni;
Yao, Dunwu;
Cao, Lizhi;
Chen, Yun;
Fu, Yilan;
Yang, Nong;
Xiang, Daxiong

Publication type:

Article

Effects of piperine–haloperidol mixture on ketamine induced schizophrenia rats and metabolism-mediated inhibitory potency: in-vivo and in-vitro evaluation.

Published in:

3 Biotech, 2024, v. 14, n. 12, p. 1, doi. 10.1007/s13205-024-04160-x

By:

Pradeepa, B. R.;
Vijayakumar, T. M.;
Manikandan, K.

Publication type:

Article

CYP2D6 and CYP2C19 Variant Coverage of Commercial Antidepressant Pharmacogenomic Testing Panels Available in Victoria, Australia.

Published in:

Genes, 2023, v. 14, n. 10, p. 1945, doi. 10.3390/genes14101945

By:

Forbes, Malcolm;
Hopwood, Mal;
Bousman, Chad A.

Publication type:

Article

Genetic Polymorphisms of Cytochromes P450 in Finno-Permic Populations of Russia.

Published in:

Genes, 2022, v. 13, n. 12, p. 2353, doi. 10.3390/genes13122353

By:

Dzhaubermezov, Murat;
Ekomasova, Natalya;
Mustafin, Rustam;
Gabidullina, Lilia;
Galimova, Yuliya;
Nurgalieva, Alfiya;
Valova, Yana;
Prokofyeva, Darya;
Khusnutdinova, Elza

Publication type:

Article

The Influence of CYP2D6 and CYP2C19 Genetic Variation on Diabetes Mellitus Risk in People Taking Antidepressants and Antipsychotics.

Published in:

Genes, 2021, v. 12, n. 11, p. 1758, doi. 10.3390/genes12111758

By:

Austin-Zimmerman, Isabelle;
Wronska, Marta;
Wang, Baihan;
Irizar, Haritz;
Thygesen, Johan H.;
Bhat, Anjali;
Denaxas, Spiros;
Fatemifar, Ghazaleh;
Finan, Chris;
Harju-Seppänen, Jasmine;
Giannakopoulou, Olga;
Kuchenbaecker, Karoline;
Zartaloudi, Eirini;
McQuillin, Andrew;
Bramon, Elvira

Publication type:

Article

Genetic Findings as the Potential Basis of Personalized Pharmacotherapy in Phelan-McDermid Syndrome.

Published in:

Genes, 2021, v. 12, n. 8, p. 1192, doi. 10.3390/genes12081192

By:

Dyar, Brianna;
Meaddough, Erika;
Sarasua, Sara M.;
Rogers, Curtis;
Phelan, Katy;
Boccuto, Luigi

Publication type:

Article

Explore the distribution of (rs35742686, rs3892097 and rs1065852) genetic polymorphisms of cytochrome P4502D6 gene in the Moroccan population.

Published in:

Egyptian Journal of Medical Human Genetics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s43042-022-00369-8

By:

El Akil, Soumaya;
Elouilamine, Ezohra;
Ighid, Nassima;
Izaabel, El Hassan

Publication type:

Article

Influence of CYP2D6, CYP2C19 and CYP3A5 polymorphisms on plasma levels of tamoxifen metabolites in Algerian women with ER<sup>+</sup> breast cancer.

Published in:

Egyptian Journal of Medical Human Genetics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s43042-022-00332-7

By:

Boucenna, Amira;
Boudaoud, Khadidja;
Hireche, Ahmed;
Rezgoune, Mohamed Larbi;
Abadi, Noureddine;
Filali, Taha;
Satta, Dalila

Publication type:

Article

Frequent Atrial Fibrillation in CYP2D6 Deficiency.

Published in:

JAFIB: Journal of Atrial Fibrillation, 2014, v. 6, n. 5, p. 95

By:

Daniell, Harry W.

Publication type:

Article

Cytochrome P450-2D6 Genotype Definition May Improve Therapy for Paroxysmal Atrial Fibrillation: A Case of Syncope Following "Pill-in-the-Pocket" Quinidine plus Propafenone.

Published in:

2014

By:

Daniell, Harry W.

Publication type:

Case Study

Unidentified CYP2D6 genotype does not affect pharmacological treatment for patients with first episode psychosis.

Published in:

Journal of Psychopharmacology, 2024, v. 38, n. 12, p. 1111, doi. 10.1177/02698811241279022

By:

De Brabander, Emma Y;
van Amelsvoort, Thérèse;
van Westrhenen, Roos

Publication type:

Article

Clinical effects of CYP2D6 phenoconversion in patients with psychosis.

Published in:

Journal of Psychopharmacology, 2024, v. 38, n. 12, p. 1095, doi. 10.1177/02698811241278844

By:

De Brabander, Emma Y;
Breddels, Esmee;
van Amelsvoort, Therese;
van Westrhenen, Roos

Publication type:

Article

Long-read sequencing of CYP2D6 may improve psychotropic prescribing and treatment outcomes: A systematic review and meta-analysis.

Published in:

Journal of Psychopharmacology, 2024, v. 38, n. 9, p. 771, doi. 10.1177/02698811241268899

By:

Kaptsis, Dean;
Lewis, Martin;
Sorich, Michael;
Battersby, Malcolm

Publication type:

Article

The pharmacokinetics and pharmacodynamics of ibogaine in opioid use disorder patients.

Published in:

Journal of Psychopharmacology, 2024, v. 38, n. 5, p. 481, doi. 10.1177/02698811241237873

By:

Knuijver, Thomas;
ter Heine, Rob;
Schellekens, Arnt F. A.;
Heydari, Paniz;
Lucas, Luc;
Westra, Sjoerd;
Belgers, Maarten;
van Oosteren, Toon;
Verkes, Robbert Jan;
Kramers, Cornelis

Publication type:

Article

Proportion of Antipsychotics with CYP2D6 Pharmacogenetic (PGx) Associations Prescribed in an Early Intervention in Psychosis (EIP) Cohort: A Cross-Sectional Study.

Published in:

Journal of Psychopharmacology, 2024, v. 38, n. 4, p. 382, doi. 10.1177/02698811241238283

By:

Jameson, Adam;
Faisal, Muhammad;
Fylan, Beth;
Bristow, Greg C;
Sohal, Jaspreet;
Dalton, Caroline;
Sagoo, Gurdeep S;
Cardno, Alastair G;
McLean, Samantha L

Publication type:

Article

Associations of antidepressants and antipsychotics with lipid parameters: Do CYP2C19 / CYP2D6 genes play a role? A UK population-based study.

Published in:

Journal of Psychopharmacology, 2023, v. 37, n. 4, p. 396, doi. 10.1177/02698811231152748

By:

Richards-Belle, Alvin;
Austin-Zimmerman, Isabelle;
Wang, Baihan;
Zartaloudi, Eirini;
Cotic, Marius;
Gracie, Caitlin;
Saadullah Khani, Noushin;
Wannasuphoprasit, Yanisa;
Wronska, Marta;
Dawda, Yogita;
Osborn, David PJ;
Bramon, Elvira

Publication type:

Article

Prediction of MDMA response in healthy humans: a pooled analysis of placebo-controlled studies.

Published in:

2021

By:

Studerus, Erich;
Vizeli, Patrick;
Harder, Samuel;
Ley, Laura;
Liechti, Matthias E

Publication type:

journal article

Functional phenotyping of the CYP2D6 probe drug codeine in the horse.

Published in:

BMC Veterinary Research, 2021, v. 17, n. 1, p. 1, doi. 10.1186/s12917-021-02788-y

By:

Gretler, S. R.;
Finno, C. J.;
Kass, P. H.;
Knych, H. K.

Publication type:

Article

Response to CYP2D6 substrate antidepressants is predicted by a CYP2D6 composite phenotype based on genotype and comedications with CYP2D6 inhibitors.

Published in:

Journal of Neural Transmission, 2015, v. 122, n. 1, p. 35, doi. 10.1007/s00702-014-1273-4

By:

Gressier, F.;
Verstuyft, C.;
Hardy, P.;
Becquemont, L.;
Corruble, E.

Publication type:

Article

Prediction of combination effect of quinidine on the pharmacokinetics of tipepidine using a physiologically based pharmacokinetic model.

Published in:

Xenobiotica, 2024, v. 54, n. 3, p. 107, doi. 10.1080/00498254.2024.2304129

By:

Hayashi, Shun;
Kawaguchi, Hiroko;
Watanabe, Takao;
Miyawaki, Izuru;
Fukami, Tatsuki;
Nakajima, Miki

Publication type:

Article

High-throughput assay to simultaneously evaluate activation of CYP3A and the direct and time-dependent inhibition of CYP3A, CYP2C9, and CYP2D6 using liquid chromatography-tandem mass spectrometry.

Published in:

Xenobiotica, 2024, v. 54, n. 2, p. 45, doi. 10.1080/00498254.2024.2308818

By:

Yumoto, Yu;
Endo, Takuro;
Harada, Hiroshi;
Kobayashi, Kaoru;
Nakabayashi, Takeshi;
Abe, Yoshikazu

Publication type:

Article

N, N-dimethyltryptamine forms oxygenated metabolites via CYP2D6 - an in vitro investigation.

Published in:

Xenobiotica, 2023, v. 53, n. 8/9, p. 515, doi. 10.1080/00498254.2023.2278488

By:

Eckernäs, Emma;
Macan-Schönleben, Alicia;
Andresen-Bergström, Moa;
Birgersson, Sofia;
Hoffmann, Kurt-Jürgen;
Ashton, Michael

Publication type:

Article

Estimation of contribution of CYP2D6 to tipepidine metabolism in humans and prolongation of the half-life of tipepidine by combination use with a CYP2D6 inhibitor in chimeric mice with humanised liver.

Published in:

Xenobiotica, 2023, v. 53, n. 4, p. 241, doi. 10.1080/00498254.2023.2224863

By:

Hayashi, Shun;
Kawaguchi, Hiroko;
Watanabe, Takao;
Miyawaki, Izuru;
Fukami, Tatsuki;
Nakajima, Miki

Publication type:

Article

Metabolism of gartanin in liver microsomes and its modulating effects on cytochrome P450s.

Published in:

Xenobiotica, 2022, v. 52, n. 4, p. 335, doi. 10.1080/00498254.2022.2076631

By:

Tao, Jia;
Ai, Hao

Publication type:

Article

Predictive role of polymorphic variants of phase II drug metabolising enzyme in modulating toxicity in North Indian lung cancer patients undergoing chemotherapy.

Published in:

Xenobiotica, 2022, v. 52, n. 3, p. 322, doi. 10.1080/00498254.2022.2069527

By:

Walia, Harleen;
Sharma, Parul;
Singh, Navneet;
Sharma, Siddharth

Publication type:

Article