Title: Ranolazine Unveiled: Rediscovering an Old Solution in a New Light.
Authors: De Santis, Giulia Azzurra; De Ferrari, Tommaso; Parisi, Francesca; Franzino, Marco; Molinero, Agustin Ezequiel; Di Carlo, Alessandro; Pistelli, Lorenzo; Vetta, Giampaolo; Parlavecchio, Antonio; Torre, Marco; Parollo, Matteo; Mansi, Giacomo; Tamborrino, Pietro Paolo; Canu, Antonio; Grifoni, Gino; Segreti, Luca; Di Cori, Andrea; Viani, Stefano Marco; Zucchelli, Giulio
Abstract: Ranolazine is an anti-anginal medication that has demonstrated antiarrhythmic properties by inhibiting both late sodium and potassium currents. Studies have shown promising results for ranolazine in treating both atrial fibrillation and ventricular arrhythmias, particularly when used in combination with other medications. This review explores ranolazine's mechanisms of action and its potential role in cardiac arrhythmias treatment in light of previous clinical studies.
Subjects: VENTRICULAR arrhythmia; ARRHYTHMIA; VENTRICULAR fibrillation; ATRIAL arrhythmias; ATRIAL fibrillation
Publication: Journal of Clinical Medicine, 2024, Vol 13, Issue 17, p4985
ISSN: 2077-0383
Publication type: Academic Journal
DOI: 10.3390/jcm13174985

Ranolazine Unveiled: Rediscovering an Old Solution in a New Light.

VENTRICULAR arrhythmia; ARRHYTHMIA; VENTRICULAR fibrillation; ATRIAL arrhythmias; ATRIAL fibrillation