Works matching DE "GUANYLATE cyclase"

Results: 1306

Implications of Oxidative Stress in the Pathophysiological Pathways of Heart Failure.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5165, doi. 10.3390/ijms26115165

By:

D'Amato, Andrea;
Cestiè, Claudia;
Ferranti, Federico;
Segato, Camilla;
Prosperi, Silvia;
Germanò, Rosanna;
Myftari, Vincenzo;
Bartimoccia, Simona;
Castellani, Valentina;
Badagliacca, Roberto;
Cammisotto, Vittoria;
Pignatelli, Pasquale;
Vizza, Carmine Dario;
Severino, Paolo

Publication type:

Article

Nociceptor-specific signaling of the receptor guanylyl cyclase Npr2 contributes to acute and persistent pain.

Published in:

Science Signaling, 2025, v. 18, n. 889, p. 1, doi. 10.1126/scisignal.adq4238

By:

Gerninghaus, Hannah;
Isensee, Jörg;
Kennel, Lea;
Zhou, Fangyuan;
Kaiser, Anja;
Gross, Tilman;
Flauaus, Cathrin;
Engel, Patrick;
Jacobs, Christoph;
Petersen, Jonas;
Kallenborn-Gerhardt, Wiebke;
Lu, Ruirui;
Metzner, Katharina;
Adler, Julia;
Ruth, Peter;
Lukowski, Robert;
Hucho, Tim;
Schmidt, Hannes;
Schmidtko, Achim

Publication type:

Article

Influence of Soluble Guanylate Cyclase on Cardiac, Vascular, and Renal Structure and Function: A Physiopathological Insight.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4550, doi. 10.3390/ijms26104550

By:

De Feo, Daniele;
Massari, Francesco;
Campanella, Cosimo;
Livrieri, Anna;
Ciccone, Marco Matteo;
Caldarola, Pasquale;
De Palo, Micaela;
Scicchitano, Pietro

Publication type:

Article

The Mechanism of Biochemical NO‐Sensing: Insights from Computational Chemistry.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 49, p. 1, doi. 10.1002/chem.202200930

By:

Rozza, Ahmed M.;
Papp, Marcell;
McFarlane, Neil R.;
Harvey, Jeremy N.;
Oláh, Julianna

Publication type:

Article

A Defined α-Helix in the Bifunctional O-Glycosylated Natriuretic Peptide TcNPa from the Venom of Tropidechis carinatus.

Published in:

Angewandte Chemie, 2015, v. 127, n. 16, p. 4910, doi. 10.1002/ange.201411914

By:

Reeks, Timothy;
Jones, Alun;
Brust, Andreas;
Sridharan, Sindhuja;
Corcilius, Leo;
Wilkinson, Brendan L.;
Thaysen ‐ Andersen, Morten;
Payne, Richard J.;
Kini, R. Manjunatha;
Daly, Norelle L.;
Alewood, Paul F.

Publication type:

Article

Plasma levels of cyclic guanosine-3′,5′-monophosphate in the cavernous and systemic blood of healthy males during different functional conditions of the penis.

Published in:

Urological Research, 2001, v. 29, n. 5, p. 366, doi. 10.1007/s002400100212

By:

Becker, Armin J.;
Ückert, Stefan;
Stief, Christian G.;
Jonas, Udo

Publication type:

Article

Slower onset of vasodilating action of brain natriuretic peptide (BNP) compared to atrial natriuretic peptide (ANP) in human forearm resistant vessels.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 9, p. 859, doi. 10.1007/s00228-008-0516-4

By:

Minami, Hironobu;
Yasu, Takanori;
Tagawa, Tatsuya;
Yamakawa, Ken;
Ueda, Shinichiro

Publication type:

Article

Soluble guanylyl cyclase activation improves progressive cardiac remodeling and failure after myocardial infarction. Cardioprotection over ACE inhibition.

Published in:

Basic Research in Cardiology, 2014, v. 109, n. 4, p. 1, doi. 10.1007/s00395-014-0421-1

By:

Fraccarollo, Daniela;
Galuppo, Paolo;
Motschenbacher, Stephanie;
Ruetten, Hartmut;
Schäfer, Andreas;
Bauersachs, Johann

Publication type:

Article

Regulation of vascular guanylyl cyclase by endothelial nitric oxide-dependent posttranslational modification.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 4, p. 539, doi. 10.1007/s00395-011-0160-5

By:

Oppermann, Marc;
Suvorava, Tatsiana;
Freudenberger, Till;
Dao, Vu;
Fischer, Jens;
Weber, Martina;
Kojda, Georg

Publication type:

Article

The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 4, p. 635, doi. 10.1007/s00395-011-0167-y

By:

Sips, Patrick;
Brouckaert, Peter;
Ichinose, Fumito

Publication type:

Article

Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 5, p. 583, doi. 10.1007/s00395-010-0098-z

By:

Klaiber, Michael;
Kruse, Martin;
Völker, Katharina;
Schröter, Juliane;
Feil, Robert;
Freichel, Marc;
Gerling, Andrea;
Feil, Susanne;
Dietrich, Alexander;
Londoño, Juan Eduardo Camacho;
Baba, Hideo A.;
Abramowitz, Joel;
Birnbaumer, Lutz;
Penninger, Josef M.;
Pongs, Olaf;
Kuhn, Michaela

Publication type:

Article

Nitric oxide/cGMP signalling mediates the cardioprotective action of adrenomedullin in reperfused myocardium.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 2, p. 257, doi. 10.1007/s00395-009-0058-7

By:

Hamid, Shabaz A.;
Totzeck, Matthias;
Drexhage, Christina;
Thompson, Iain;
Fowkes, Robert C.;
Rassaf, Tienush;
Baxter, Gary F.

Publication type:

Article

Nicorandil opens mitochondrial K<sub>ATP</sub> channels not only directly but also through a NO-PKG-dependent pathway.

Published in:

Basic Research in Cardiology, 2007, v. 102, n. 1, p. 73, doi. 10.1007/s00395-006-0612-5

By:

Kuno, Atsushi;
Critz, Stuart D.;
Cohen, Michael V.;
Downey, James M.

Publication type:

Article

Postconditioning’s protection is not dependent on circulatin blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation.

Published in:

Basic Research in Cardiology, 2005, v. 100, n. 1, p. 57, doi. 10.1007/s00395-004-0498-4

By:

Yang, Xi-Ming;
Philipp, Sebastian;
Downey, James;
Cohen, Michael

Publication type:

Article

Vascular actions of natriuretic peptides: Cyclic GMP-dependent and -independent mechanisms.

Published in:

Basic Research in Cardiology, 2004, v. 99, n. 2, p. 83, doi. 10.1007/s00395-004-0459-6

By:

Ahluwalia, Amrita;
MacAllister, Raymond J.;
Hobbs, Adrian J.

Publication type:

Article

Carbonic anhydrases are producers of S-nitrosothiols from inorganic nitrite and modulators of soluble guanylyl cyclase in human platelets.

Published in:

Amino Acids, 2016, v. 48, n. 7, p. 1695, doi. 10.1007/s00726-016-2234-z

By:

Hanff, Erik;
Böhmer, Anke;
Zinke, Maximilian;
Gambaryan, Stepan;
Schwarz, Alexandra;
Supuran, Claudiu;
Tsikas, Dimitrios

Publication type:

Article

Efficient expression of human soluble guanylate cyclase in Escherichia coli and its signaling-related interaction with nitric oxide.

Published in:

Amino Acids, 2010, v. 39, n. 2, p. 399, doi. 10.1007/s00726-009-0453-2

By:

Fangfang Zhong;
Hongyan Wang;
Tianlei Ying;
Zhong-Xian Huang;
Xiangshi Tan

Publication type:

Article

Bayer: Phase 2 Trial of Investigational Soluble Guanylate Cyclase Activator for Chronic Kidney Disease Begins.

Published in:

Patient Care (Online), 2024, p. 1

By:

Jennings, Sydney

Publication type:

Article

Melanopsin (Opn4) is an oncogene in cutaneous melanoma.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03425-6

By:

de Assis, Leonardo Vinícius Monteiro;
Lacerda, José Thalles;
Moraes, Maria Nathália;
Domínguez-Amorocho, Omar Alberto;
Kinker, Gabriela Sarti;
Mendes, Davi;
Silva, Matheus Molina;
Menck, Carlos Frederico Martins;
Câmara, Niels Olsen Saraiva;
Castrucci, Ana Maria de Lauro

Publication type:

Article

PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03140-2

By:

Hildebrand, Staffan;
Ibrahim, Mohamed;
Schlitzer, Andreas;
Maegdefessel, Lars;
Röll, Wilhelm;
Pfeifer, Alexander

Publication type:

Article

Evidence for the Role of Endogenous Carbon Monoxide in Memory Processing.

Published in:

Journal of Cognitive Neuroscience, 2007, v. 19, n. 4, p. 557, doi. 10.1162/jocn.2007.19.4.557

By:

Cutajar, M. C.;
Edwards, T. M.

Publication type:

Article

The Necklace Olfactory System in Mammals.

Published in:

Journal of Neurogenetics, 2008, v. 22, n. 3, p. 229, doi. 10.1080/01677060802340228

By:

Luo, Minmin

Publication type:

Article

sGC stimulator (BAY 41‐8543) combined with PDE9 inhibitor (BAY 73‐6691) reduces renal fibrosis in 5/6 nephrectomized rats.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2025, v. 136, n. 1, p. 1, doi. 10.1111/bcpt.14103

By:

Chen, Xin;
Delić, Denis;
Liu, Yvonne;
Cao, Yaochen;
Zhang, Zeyu;
Wu, Hongwei;
Gaballa, Mohamed M. S.;
Klein, Thomas;
Elitok, Saban;
Krämer, Bernhard K.;
Hocher, Berthold

Publication type:

Article

The importance of the nitric oxide‐cGMP pathway in age‐related cardiovascular disease: Focus on phosphodiesterase‐1 and soluble guanylate cyclase.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 127, n. 2, p. 67, doi. 10.1111/bcpt.13319

By:

Golshiri, Keivan;
Ataei Ataabadi, Ehsan;
Portilla Fernandez, Eliana C.;
Jan Danser, A. H.;
Roks, Anton J. M.

Publication type:

Article

Hypoxic augmentation: The tale of a strange contraction.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 127, n. 2, p. 59, doi. 10.1111/bcpt.13295

By:

Vanhoutte, Paul Michel;
Leung, Susan Wai Sum

Publication type:

Article

A focus on riociguat in the treatment of pulmonary arterial hypertension.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2019, v. 125, n. 3, p. 202, doi. 10.1111/bcpt.13272

By:

Toxvig, Anne Kathrine;
Wehland, Markus;
Grimm, Daniela;
Infanger, Manfred;
Krüger, Marcus

Publication type:

Article

Inhibition of Neuronal Nitric Oxide Synthase and Soluble Guanylate Cyclase Prevents Depression-Like Behaviour in Rats Exposed to Chronic Unpredictable Mild Stress.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2012, v. 111, n. 3, p. 154, doi. 10.1111/j.1742-7843.2012.00877.x

By:

Yazir, Yusufhan;
Utkan, Tijen;
Aricioglu, Feyza

Publication type:

Article

Vasodilatory Effect of n -Butanol Extract from Sanguisorba officinalis L. and Its Mechanism.

Published in:

Plants (2223-7747), 2025, v. 14, n. 7, p. 1095, doi. 10.3390/plants14071095

By:

Jin, Hangyu;
Li, Jiaze;
Wang, Shuyuan;
Jin, Enyi;
Min, Jun Zhe;
Li, Gao;
Lee, Yun Jung;
Cao, Lihua

Publication type:

Article

Phytosulfokine Regulates Growth in Arabidopsis through a Response Module at the Plasma Membrane That Includes CYCLIC NUCLEOTIDE-GATED CHANNEL17, H+-ATPase, and BAK1.

Published in:

Plant Cell, 2015, v. 27, n. 6, p. 1718, doi. 10.1105/tpc.15.00306

By:

Ladwig, Friederike;
Dahlke, Renate I.;
Stührwohldt, Nils;
Hartmann, Jens;
Harter, Klaus;
Sauter, Margret

Publication type:

Article

Soluble Guanylate Cyclase Mediates Negative Signaling by Ammonium on Expression of Nitrate Reductase in Chlamydomonas.

Published in:

Plant Cell, 2010, v. 22, n. 5, p. 1532, doi. 10.1105/tpc.108.062380

By:

Montaigu, Amaury de;
Sanz-Luque, Emanuel;
Galván, Aurora;
Fernández, Emilio

Publication type:

Article

Differential expression of the enzymes regulating myosin light chain phosphorylation are responsible for the slower relaxation of pulmonary artery than mesenteric artery in rats.

Published in:

Korean Journal of Physiology & Pharmacology, 2024, v. 28, n. 1, p. 49, doi. 10.4196/kjpp.2024.28.1.49

By:

Seung Beom Oh;
Suhan Cho;
Hyun Jong Kim;
Sung Joon Kim

Publication type:

Article

Carbon monoxide activation of delayed rectifier potassium currents of human cardiac fibroblasts through diverse pathways.

Published in:

Korean Journal of Physiology & Pharmacology, 2022, v. 26, n. 1, p. 25, doi. 10.4196/kjpp.2022.26.1.25

By:

Hyemi Bae;
Taeho Kim;
Inja Lim

Publication type:

Article

Carbon monoxide activates large-conductance calcium-activated potassium channels of human cardiac fibroblasts through various mechanisms.

Published in:

Korean Journal of Physiology & Pharmacology, 2021, v. 25, n. 3, p. 227, doi. 10.4196/kjpp.2021.25.3.227

By:

Hyemi Bae;
Taeho Kim;
Inja Lim

Publication type:

Article

Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons.

Published in:

Korean Journal of Physiology & Pharmacology, 2012, v. 16, n. 3, p. 211, doi. 10.4196/kjpp.2012.16.3.211

By:

Yunju Jin;
Jun Kim;
Jiyeon Kwak

Publication type:

Article

An analysis of inhibitory junction potentials in the guinea-pig proximal colon.

Published in:

Journal of Physiology, 2004, v. 558, n. 3, p. 841, doi. 10.1113/jphysiol.2004.065052

By:

Hirst, G. D. S.;
Bywater, R. A. R.;
Teramoto, N.;
Edwards, F. R.

Publication type:

Article

Cirrhosis decreases vasoconstrictor response to electrical field stimulation in rat mesenteric artery: role of calcitonin gene-related peptide.

Published in:

Experimental Physiology, 2011, v. 96, n. 3, p. 275, doi. 10.1113/expphysiol.2010.055822

By:

Blanco-Rivero, Javier;
Márquez-Rodas, Iván;
Sastre, Esther;
Cogolludo, Ángel;
Pérez-Vizcaíno, Francisco;
Del Campo, Lara;
Nava, Ma. Paz;
Balfagón, Gloria

Publication type:

Article

Propyretic role of the locus coeruleus nitric oxide pathway.

Published in:

Experimental Physiology, 2010, v. 95, n. 6, p. 669, doi. 10.1113/expphysiol.2009.051490

By:

Soriano, Renato N.;
Ravanelli, Maria I.;
Batalhao, Marcelo E.;
Carnio, Evelin C.;
Branco, Luiz G. S.

Publication type:

Article

Distinct prognostic value of mRNA expression of guanylate-binding protein genes in skin cutaneous melanoma.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 7914, doi. 10.3892/ol.2018.8306

By:

Wang, Qiaoqi;
Wang, Xiangkun;
Liang, Qian;
Wang, Shijun;
Xiwen, Liao;
Pan, Fuqiang;
Chen, Hongyang;
Li, Dong

Publication type:

Article

Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase.

Published in:

Oncology Letters, 2015, v. 10, n. 1, p. 479, doi. 10.3892/ol.2015.3229

By:

XIAOYUAN YAO;
YAN WU;
MIAOLIN ZHU;
HAI QIAN;
YONGCHANG CHEN

Publication type:

Article

Enhanced Structure Prediction of Gene Products Containing Class III Adenylyl Cyclase Domains.

Published in:

In Silico Biology, 2006, v. 6, n. 5, p. 351, doi. 10.3233/isb-00248

By:

Reddy, Chandrashekar;
Manonmani, Arunachalam;
Babu, Meenakshi;
Sowdhamini, Ramanathan

Publication type:

Article

Heme‐induced corpus cavernosum relaxation and its implications for priapism in sickle cell disease: a mechanistic insight.

Published in:

Andrology, 2024, v. 12, n. 8, p. 1857, doi. 10.1111/andr.13599

By:

Pereira, Dalila Andrade;
Pereira, Danillo Andrade;
Silveira, Tammyris Helena Rebecchi;
Calmasini, Fabiano Beraldi;
Burnett, Arthur L.;
Costa, Fernando Ferreira;
Silva, Fábio Henrique

Publication type:

Article

6‐Nitrodopamine is an endogenous mediator of the rabbit corpus cavernosum relaxation.

Published in:

Andrology, 2024, v. 12, n. 6, p. 1419, doi. 10.1111/andr.13585

By:

Lima, Antonio Tiago;
Britto‐Júnior, José;
Moraes, Manoel Odorico;
Moraes, Maria Elisabete A.;
Fregonesi, Adriano;
Monica, Fabíola Z.;
Antunes, Edson;
De Nucci, Gilberto

Publication type:

Article

Study of the Differentially Expressed Genes in the Pomacea canaliculata Transcriptome after Treatment with Pedunsaponin A.

Published in:

Metabolites (2218-1989), 2019, v. 9, n. 11, p. 268, doi. 10.3390/metabo9110268

By:

Yang, Chunping;
Lv, Tianxing;
Zhang, Yangyang;
Wang, Bin;
Zhao, Xiaomin;
Zhang, Min;
Gong, Guoshu;
Chang, Xiaoli;
Yue, Guizhou;
Qiu, Xiaoyan;
Luo, Liya;
Chen, Huabao

Publication type:

Article

Management of Pulmonary Arterial Hypertension: Current Strategies and Future Prospects.

Published in:

Life (2075-1729), 2025, v. 15, n. 3, p. 430, doi. 10.3390/life15030430

By:

Sharma, Munish;
Paudyal, Vivek;
Syed, Saifullah Khalid;
Thapa, Rubi;
Kassam, Nadeem;
Surani, Salim

Publication type:

Article

Renewal and Differentiation of GCD Necklace Olfactory Sensory Neurons.

Published in:

Chemical Senses, 2020, v. 45, n. 5, p. 333, doi. 10.1093/chemse/bjaa027

By:

Bloom, Maria Lissitsyna;
Johnston, Lucille B;
Datta, Sandeep Robert

Publication type:

Article

The Receptor Guanylyl Cyclase Type D (GC-D) Ligand Uroguanylin Promotes the Acquisition of Food Preferences in Mice.

Published in:

Chemical Senses, 2013, v. 38, n. 5, p. 391, doi. 10.1093/chemse/bjt015

By:

Arakawa, Hiroyuki;
Kelliher, Kevin R.;
Zufall, Frank;
Munger, Steven D.

Publication type:

Article

Intrinsic Nitric Oxide Regulates the Taste Response of the Sugar Receptor Cell in the Blowfly, Phormia regina.

Published in:

Chemical Senses, 2004, v. 29, n. 1, p. 75, doi. 10.1093/chemse/bjh007

By:

Murata, Yoshihiro;
Mashiko, Masashi;
Ozaki, Mamiko;
Amakawa, Taisaku;
Nakamura, Tadashi

Publication type:

Article

Protoporphyrin IX Stimulates Melanogenesis, Melanocyte Dendricity, and Melanosome Transport Through the cGMP/PKG Pathway.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.569368

By:

Lv, Jinpeng;
An, Xiaohong;
Jiang, Songzhou;
Yang, Ying;
Song, Guoqiang;
Gao, Rongyin

Publication type:

Article

Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00419

By:

Zimmer, Daniel P.;
Shea, Courtney M.;
Tobin, Jenny V.;
Tchernychev, Boris;
Germano, Peter;
Sykes, Kristie;
Banijamali, Ali R.;
Jacobson, Sarah;
Bernier, Sylvie G.;
Sarno, Renee;
Carvalho, Andrew;
Chien, Yueh-tyng;
Graul, Regina;
Buys, Emmanuel S.;
Jones, Juli E.;
Wakefield, James D.;
Price, Gavrielle M.;
Chickering, Jennifer G.;
Milne, G. Todd;
Currie, Mark G.

Publication type:

Article

Shenfu Injection Promotes Vasodilation by Enhancing eNOS Activity Through the PI3K/Akt Signaling Pathway In Vitro.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00121

By:

Zhu, Jinqiang;
Song, Wanshan;
Xu, Shixin;
Ma, Yan;
Wei, Baoyu;
Wang, Hongwu;
Hua, Shengyu

Publication type:

Article