Works matching DE "IMMUNE checkpoint proteins"

Results: 5000

Spatial Heterogeneity of Intratumoral Microbiota: A New Frontier in Cancer Immunotherapy Resistance.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1261, doi. 10.3390/biomedicines13051261

By:

Tan, Qiwen;
Cao, Xiongjing;
Zou, Falong;
Wang, Hanwenchen;
Xiong, Lijuan;
Deng, Shenghe

Publication type:

Article

The Development and Assessment of a Unique Disulfidptosis-Associated lncRNA Profile for Immune Microenvironment Prediction and Personalized Therapy in Gastric Adenocarcinoma.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1224, doi. 10.3390/biomedicines13051224

By:

Zhu, Jiyue;
Zhu, Xiang;
Su, Tingting;
Zhou, Huiqing;
Wang, Shouhua;
Shi, Weibin

Publication type:

Article

Transposable Element Is Predictive of Chemotherapy- and Immunotherapy-Related Overall Survival in Glioma.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1177, doi. 10.3390/biomedicines13051177

By:

Peng, Bi;
Shen, Fan;
Chen, Ziqi;
Yu, Yongkai;
Liu, Rundong;
Zhang, Yiling;
Long, Guoxian;
Hu, Guangyuan;
Liu, Yuanhui

Publication type:

Article

The Role of Tregs in the Tumor Microenvironment.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1173, doi. 10.3390/biomedicines13051173

By:

Sato, Yohei

Publication type:

Article

G-Quadruplexes in Tumor Immune Regulation: Molecular Mechanisms and Therapeutic Prospects in Gastrointestinal Cancers.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1057, doi. 10.3390/biomedicines13051057

By:

Zhou, Yunxia;
Xu, Difei;
Zhang, Ying;
Zhou, Huaixiang

Publication type:

Article

The Interplay Between DNA Repair and the Immune Microenvironment in Pancreatic Cancer.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1031, doi. 10.3390/biomedicines13051031

By:

Ciner, Aaron;
Hosein, Peter J.;
Jiang, Yixing;
Rassool, Feyruz

Publication type:

Article

SMARCB1 Deficiency as a Driver of the Hallmarks of Cancer in Rhabdoid Tumours: Novel Insights into Dysregulated Energy Metabolism, Emerging Targets, and Ongoing Clinical Trials.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 5, p. 304, doi. 10.3390/metabo15050304

By:

Shakerdi, Abdul L.;
Pidgeon, Graham P.

Publication type:

Article

Tumor-Associated Macrophages: Polarization, Immunoregulation, and Immunotherapy.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 741, doi. 10.3390/cells14100741

By:

Saeed, Abdullah Farhan

Publication type:

Article

CD99: A Key Regulator in Immune Response and Tumor Microenvironment.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 632, doi. 10.3390/biom15050632

By:

Manara, Maria Cristina;
Fiori, Valentina;
Sparti, Angelo;
Scotlandi, Katia

Publication type:

Article

Precision Targeting in Metastatic Prostate Cancer: Molecular Insights to Therapeutic Frontiers.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 625, doi. 10.3390/biom15050625

By:

Kwon, Whi-An;
Joung, Jae Young

Publication type:

Article

Unsupervised Clustering of Cell Populations in Germinal Centers Using Multiplexed Immunofluorescence.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 530, doi. 10.3390/biology14050530

By:

Burgermeister, Simon;
Orfanakis, Michail;
Georgakis, Spiros;
Brenna, Cloe;
Lindsay, Helen;
Fenwick, Craig;
Pantaleo, Giuseppe;
Gottardo, Raphael;
Petrovas, Constantinos

Publication type:

Article

Computational Design of a Bicyclic Peptide Inhibitor Targeting the ICOS/ICOS‐L Protein–Protein Interaction.

Published in:

Chemical Biology & Drug Design, 2025, v. 105, n. 5, p. 1, doi. 10.1111/cbdd.70117

By:

Calvo‐Barreiro, Laura;
Secor, Maxim;
Damjanovic, Jovan;
Abdel‐Rahman, Somaya A.;
Lin, Yu‐Shan;
Gabr, Moustafa

Publication type:

Article

Soluble Immune Checkpoints Associated With Disease Activity and Treatment Response in GD and TED.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 6, p. 1537, doi. 10.1210/clinem/dgae763

By:

Yin, Qinglei;
Zhu, Tianyi;
Song, Dalong;
Fang, Sijie;
Zhou, Huifang;
Guan, Haixia

Publication type:

Article

Prognostic Value of B7-H3 and a Novel Scoring System in Localized Renal Cell Carcinoma.

Published in:

Medicina (1010660X), 2025, v. 61, n. 5, p. 867, doi. 10.3390/medicina61050867

By:

Özalp, Faruk Recep;
Yörükoğlu, Kutsal;
Çalışkan Yıldırım, Eda;
Uzun, Mehmet;
Demirciler, Erkut;
Semiz, Hüseyin Salih

Publication type:

Article

Thymidine kinase 1 indicates resistance to immune checkpoint plus tyrosine kinase inhibition in renal cell carcinoma.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 775, doi. 10.1007/s13402-025-01048-7

By:

Wang, Jiajun;
Xu, Xianglai;
Wang, Ying;
Zhu, Yanjun

Publication type:

Article

Immunological features of various molecular subtypes of cervical cancer and their prognostic implications in the context of disulfidptosis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1574911

By:

Yao, Yadan;
Yang, Xiaomin;
Fu, Yuanxin;
Zhang, Yinmin

Publication type:

Article

Unraveling the immune evasion mechanisms in the tumor microenvironment of head and neck squamous cell carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1597202

By:

Zhao, Xuri;
Zhu, Yaping;
He, Youya;
Gu, Weiyan;
Zhou, Qi;
Jin, Bei;
Chen, Shenguo;
Lin, Haisheng

Publication type:

Article

Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1457204

By:

Xu, Yupeng;
Sun, Jian;
Yan, Xin;
Mao, Zhenliao;
Chen, Yiming

Publication type:

Article

Immune Modulation During Treatment with Enzalutamide Alone or with Radium-223 in Patients with Castration Resistant Prostate Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1730, doi. 10.3390/cancers17101730

By:

Zang, Peter D.;
Da Silva, Diane M.;
Liu, Zhang-Xu;
Kandukuri, Shivani;
Tsao-Wei, Denice;
D'Souza, Anishka;
Kast, W. Martin;
Pal, Sumanta K.;
Kefauver, Cheryl;
Juanqueira, Maribel;
Yang, Lixin;
Quinn, David I.;
Dorff, Tanya B.

Publication type:

Article

Current and Emerging Insights into the Causes, Immunopathogenesis, and Treatment of Cutaneous Squamous Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1702, doi. 10.3390/cancers17101702

By:

Anderson, Ronald;
Mkhize, Nomzamo M.;
Kgokolo, Mahlatse M. C.;
Steel, Helen C.;
Rossouw, Theresa M.;
Anderson, Lindsay;
Rapoport, Bernardo L.

Publication type:

Article

The Spatial Proximity of CD8 + FoxP3 + PD-1 + Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer.

Published in:

Current Oncology, 2025, v. 32, n. 5, p. 262, doi. 10.3390/curroncol32050262

By:

Hu, Zijuan;
Hu, Zhihuang;
Chen, Keji;
Huang, Huixia;
Zhong, Xinyang;
Wang, Yaxian;
Chen, Jiayu;
He, Xuefeng;
Shi, Di;
Zeng, Yupeng;
Li, Jiwei;
Zhou, Xiaoyan;
Wei, Ping

Publication type:

Article

Integrative Analysis of Immune- and Metabolism-Related Genes Identifies Robust Prognostic Signature and PYCR1 as a Carcinogenic Regulator in Clear Cell Renal Cell Carcinoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4953, doi. 10.3390/ijms26104953

By:

Zhao, Guo;
Ding, Jiatong;
Ma, Jiaxiu;
Jiang, Yale;
Wang, Yuning;
Wang, Shuhang;
Li, Ning

Publication type:

Article

A Comprehensive Review of Long Non-Coding RNAs in the Cancer–Immunity Cycle: Mechanisms and Therapeutic Implications.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4821, doi. 10.3390/ijms26104821

By:

Perez-Medina, Mario;
Benito-Lopez, Jesus J.;
Aguilar-Cazares, Dolores;
Lopez-Gonzalez, Jose S.

Publication type:

Article

NetLnc: A Network-Based Computational Framework to Identify Immune Checkpoint-Related lncRNAs for Immunotherapy Response in Melanoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4557, doi. 10.3390/ijms26104557

By:

Lu, Qianyi;
Li, Jian;
Chen, Wenli;
Wang, Zhuoru;
Wang, Di;
Liu, Chenyu;
Sun, Yue;
Jiang, Han;
Zhang, Caiyu;
Chang, Yetong;
Zhou, Jiajun;
Wu, Xiaohong;
Gao, Yue;
Ning, Shangwei

Publication type:

Article

Molecular Dynamics-Guided Repositioning of FDA-Approved Drugs for PD-L1 Inhibition with In Vitro Anticancer Potential.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4497, doi. 10.3390/ijms26104497

By:

Jiang, Dejun;
Yoou, Myoung-Schook;
Cho, Sungjoon;
Choi, Youngjin

Publication type:

Article

Identification of genetically engineered strategies to manipulate nano-platforms presenting immunotherapeutic ligands for alleviating primary ovarian insufficiency progression.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02226-8

By:

Zhou, Guannan;
Gu, Yuanyuan;
Zhang, Menglei;
Ding, Jingxin;
Lu, Guanming;
Hua, Keqin;
Shen, Fang

Publication type:

Article

Classification of Glioblastoma Associated with Immune Checkpoints and Tumor Microenvironment based on Immunogenomic Profiling.

Published in:

Neurology India, 2024, v. 72, n. 2, p. 297, doi. 10.4103/ni.ni_1070_21

By:

Ping Zheng;
Xiaoxue Zhang;
Dabin Ren;
Qingke Bai

Publication type:

Article

Bioinformatic analysis of the role of immune checkpoint genes and immune infiltration in the pathogenesis and development of premature ovarian insufficiency.

Published in:

Journal of Assisted Reproduction & Genetics, 2024, v. 41, n. 6, p. 1619, doi. 10.1007/s10815-024-03120-x

By:

Zhang, Xiyan;
Wang, Ling;
Yang, Tongkun;
Kong, Li;
Wei, Luxiao;
Du, Jing

Publication type:

Article

PD‐L1, PD‐1, and CTLA‐4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 141, doi. 10.1111/vco.13039

By:

Foiani, Greta;
Melchiotti, Erica;
Capello, Katia;
Porcellato, Ilaria;
Brachelente, Chiara;
Iussich, Selina;
Giacobino, Davide;
Morello, Emanuela;
Martano, Marina;
Buracco, Paolo;
Vascellari, Marta

Publication type:

Article

Immunohistochemical Expression of Programmed Death‐Ligand 1 and Cytotoxic T‐Lymphocyte Antigen‐4 in Canine Cutaneous Mast Cell Tumours.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 1, p. 109, doi. 10.1111/vco.13036

By:

Ribeiro, Mariana Pinto;
Canadas‐Sousa, Ana;
Aluai‐Cunha, Catarina;
de Fátima Carvalho, Maria;
Santos, Andreia Ferreira

Publication type:

Article

Stromal Expression Profiling Reveals Immune‐Driven Adaption to Malignancy in Canine Melanoma Subtypes.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 1, p. 20, doi. 10.1111/vco.13021

By:

Beebe, Erin;
Krudewig, Christiane;
Motamed, Zahra;
Malbon, Alexandra;
Markkanen, Enni

Publication type:

Article

Inhibitory checkpoint molecule mRNA expression in canine soft tissue sarcoma.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 4, p. 709, doi. 10.1111/vco.12934

By:

Stevenson, Valentina Beatriz;
Gudenschwager‐Basso, Erwin Kristobal;
Klahn, Shawna;
LeRoith, Tanya;
Huckle, William R.

Publication type:

Article

Tumour necrosis factor stimulated gene 6 intrinsically regulates PD‐L1 expressions in breast cancer cells, leading to modulation of tumour microenvironment.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 2, p. 255, doi. 10.1111/vco.12884

By:

Lee, Jeong‐Hwa;
An, Ju‐Hyun;
Youn, Hwa‐Young

Publication type:

Article

VCS abstract.

Published in:: Veterinary & Comparative Oncology, 2023, v. 21, p. 3, doi. 10.1111/vco.12867
Publication type:: Article

Evaluation of lymphocyte‐specific programmed cell death protein 1 receptor expression and cytokines in blood and urine in canine urothelial carcinoma patients.

Published in:

Veterinary & Comparative Oncology, 2022, v. 20, n. 2, p. 427, doi. 10.1111/vco.12788

By:

Pinard, Christopher J.;
Stegelmeier, Ashley A.;
Bridle, Byram W.;
Mutsaers, Anthony J.;
Wood, R. Darren;
Wood, Geoffrey A.;
Woods, J. Paul;
Hocker, Samuel E.

Publication type:

Article

Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune‐Related Lectins.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 29, p. 7951, doi. 10.1002/chem.202100800

By:

Lima, Carlos D. L.;
Coelho, Helena;
Gimeno, Ana;
Trovão, Filipa;
Diniz, Ana;
Dias, Jorge S.;
Jiménez‐Barbero, Jesús;
Corzana, Francisco;
Carvalho, Ana Luísa;
Cabrita, Eurico J.;
Marcelo, Filipa

Publication type:

Article

Investigation the immunotherapeutic potential of miR-4477a targeting PD-1/PD-L1 in breast cancer cell line using a CD8<sup>+</sup> co-culture model.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10435-0

By:

Tülüce, Yasin;
Köstekci, Sedat;
Karakuş, Fuat;
Keleş, Ahmet Yasin;
Tunçyürekli, Merve

Publication type:

Article

Effect of FLT3 ligand on the gene expression of TIM-3, HIF1-α, and TNF-α in an acute myeloid leukemia cell line.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10396-4

By:

Heidari, Fatemeh;
Kazemi-Sefat, Nazanin Atieh;
Feizollahi, Parisa;
Gerdabi, Sajjad;
Pourfathollah, Ali Akbar;
Ebtekar, Masoumeh

Publication type:

Article

Assessment of the circulating levels of immune system checkpoint selected biomarkers in patients with lung cancer.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09971-y

By:

Safizadeh, Banafsheh;
Sadeh, Maryam;
Robati, Ali Karami;
Riahi, Taghi;
Tavakoli-Yaraki, Masoumeh

Publication type:

Article

Galectin-9, a pro-survival factor inducing immunosuppression, leukemic cell transformation and expansion.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09563-w

By:

Yıldırım, Cansu

Publication type:

Article

The antigen‐binding moiety in the driver's seat of CARs.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 1, p. 306, doi. 10.1002/med.21818

By:

Hanssens, Heleen;
Meeus, Fien;
De Veirman, Kim;
Breckpot, Karine;
Devoogdt, Nick

Publication type:

Article

Effects of sex and obesity on immune checkpoint inhibition-related cardiac systolic dysfunction in aged mice.

Published in:

Basic Research in Cardiology, 2025, v. 120, n. 1, p. 207, doi. 10.1007/s00395-024-01088-4

By:

Sayour, Nabil V.;
Kucsera, Dániel;
Alhaddad, Ayham R.;
Tóth, Viktória É.;
Gergely, Tamás G.;
Kovács, Tamás;
Hegedűs, Zsombor I.;
Jakab, Márk E.;
Ferdinandy, Péter;
Varga, Zoltán V.

Publication type:

Article

Preclinical models of cardiotoxicity from immune checkpoint inhibitor therapy.

Published in:

Basic Research in Cardiology, 2025, v. 120, n. 1, p. 171, doi. 10.1007/s00395-024-01070-0

By:

Buehning, Florian;
Lerchner, Tobias;
Vogel, Julia;
Hendgen-Cotta, Ulrike B.;
Totzeck, Matthias;
Rassaf, Tienush;
Michel, Lars

Publication type:

Article

PD-L1 importance in malignancies comprehensive insights into the role of PD-L1 in malignancies: from molecular mechanisms to therapeutic opportunities.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01641-y

By:

Soltani, Mojdeh;
Abbaszadeh, Mohammad;
Fouladseresht, Hamed;
Sullman, Mark J. M.;
Eskandari, Nahid

Publication type:

Article

Identifying the prognostic significance of mitophagy-associated genes in multiple myeloma: a novel risk model construction.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01499-6

By:

Min, Rui;
Hu, Zeyu;
Zhou, Yulan

Publication type:

Article

SASS6 promotes tumor proliferation and is associated with TP53 and immune infiltration in lung adenocarcinoma.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01510-0

By:

Li, Zihao;
He, Lingyun;
Li, Jiayi;
Qian, Jing;
Wu, Zuotao;
Zhu, Yongjie;
Zhuo, Ting;
Nong, Jusen;
Liang, Honghua;
Zheng, Hua;
Huang, Weijia;
Huang, Julu;
Cao, Jianbin

Publication type:

Article

APOBEC family reshapes the immune microenvironment and therapy sensitivity in clear cell renal cell carcinoma.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01465-2

By:

Huang, Guiying;
Zhan, Xianlin;
Shen, Lihong;
Lou, Luping;
Dai, Yuehong;
Jiang, Aiming;
Gao, Yuzhen;
Wang, Yanzhong;
Xie, Xinyou;
Zhang, Jun

Publication type:

Article

TESC associated with poor prognosis enhances cancer stemness and migratory properties in liver cancer.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01469-y

By:

Ye, Peng;
Luo, Shahang;
Huang, Junyu;
Fu, Xihua;
Chi, Xiaoxia;
Cha, Jong-Ho;
Chen, Yumei;
Mai, Yanjun;
Hsu, Kai-Wen;
Yan, Xiuwen;
Yang, Wen-Hao

Publication type:

Article

Hepatocellular Carcinoma Subtyping and Prognostic Model Construction Based on Chemokine-Related Genes.

Published in:

Medical Principles & Practice, 2023, v. 32, n. 6, p. 332, doi. 10.1159/000534537

By:

Guo, Qiusheng;
Huang, Yangyang;
Zhan, Xiaoan

Publication type:

Article

The Renaissance of Interest in Breast Cancer Treatment by PD1/PDL1 Checkpoint Inhibitors.

Published in:

Zagazig University Medical Journal, 2023, v. 29, n. 4, p. 1007, doi. 10.21608/zumj.2022.100350.2374

By:

Muhammad, Shireen S.;
Ismail, Eman I.;
Abdelaziz, Lobna A.;
Elsebai, Eman

Publication type:

Article