Works matching DE "ALLOSTERIC proteins"

Results: 385

An NMR method for studying the kinetics of metal exchange in biomolecular systems.

Published in:

Journal of Biomolecular NMR, 2002, v. 23, n. 4, p. 303, doi. 10.1023/A:1020245031235

By:

Barbieri, Renato;
Hore, P. J.;
Luchinat, Claudio;
Pierattelli, Roberta

Publication type:

Article

Structure-based prediction of protein-protein binding affinity with consideration of allosteric effect.

Published in:

Amino Acids, 2012, v. 43, n. 2, p. 531, doi. 10.1007/s00726-011-1101-1

By:

Tian, Feifei;
Lv, Yonggang;
Yang, Li

Publication type:

Article

SigrafW: An Easy-to-use Program for Fitting Enzyme Kinetic Data.

Published in:

Biochemistry & Molecular Biology Education, 2005, v. 33, n. 6, p. 399, doi. 10.1002/bmb.2005.49403306399

By:

Leone, Francisco Assis;
Baranauskas, José Augusto;
Furriel, Rosa Prazeres Melo;
Borin, Ivana Aparecida

Publication type:

Article

A parameterized two-domain thermodynamic model explains diverse mutational effects on protein allostery.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.92262

By:

Zhuang Liu;
Gillis, Thomas G.;
Raman, Srivatsan;
Qiang Cui

Publication type:

Article

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91777

By:

Dolcemascolo, Roswitha;
Heras-Hernández, María;
Goiriz, Lucas;
Montagud-Martínez, Roser;
Requena-Menéndez, Alejandro;
Ruiz, Raúl;
Pérez-Ràfols, Anna;
Higuera-Rodríguez, R. Anahí;
Pérez-Ropero, Guillermo;
Vranken, Wim F.;
Martelli, Tommaso;
Kaiser, Wolfgang;
Buijs, Jos;
Rodrigo, Guillermo

Publication type:

Article

Allosteric regulation of kinase activity in living cells.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.90574

By:

Godbole, Shivani Sujay;
Dokholyan, Nikolay V.

Publication type:

Article

Divalent cations in human liver pyruvate kinase exemplify the combined effects of complex-equilibrium and allosteric regulation.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-36943-2

By:

Martin, Tyler A.;
Fenton, Aron W.

Publication type:

Article

mGluR5 positive allosteric modulation and its effects on MK-801 induced set-shifting impairments in a rat operant delayed matching/non-matching-to-sample task.

Published in:

Psychopharmacology, 2015, v. 232, n. 1, p. 251, doi. 10.1007/s00213-014-3653-8

By:

LaCrosse, Amber;
Burrows, Brian;
Angulo, Rachel;
Conrad, Phoebe;
Himes, Sarah;
Mathews, Nordia;
Wegner, Scott;
Taylor, Sara;
Olive, M.

Publication type:

Article

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT receptor signaling: mechanistic studies.

Published in:

Psychopharmacology, 2015, v. 232, n. 1, p. 259, doi. 10.1007/s00213-014-3657-4

By:

Wierońska, Joanna;
Sławińska, Anna;
Łasoń-Tyburkiewicz, Magdalena;
Gruca, Piotr;
Papp, Mariusz;
Zorn, Stevin;
Doller, Darío;
Kłeczek, Natalia;
Noworyta-Sokołowska, Karolina;
Gołembiowska, Krystyna;
Pilc, Andrzej

Publication type:

Article

Assignment1 of the human ADP-ribosylation factor 6 (ARF6) gene to chromosome 7q22.1 by radiation hybrid mapping.

Published in:

Cytogenetics & Cell Genetics, 1999, v. 84, n. 1/2, p. 94, doi. 10.1159/000015225

By:

Kim, H.-S.

Publication type:

Article

Addendum: Sensing the allosteric force.

Published in:

Nature Communications, 2023, v. 14, p. 1, doi. 10.1038/s41467-023-37893-z

By:

Jankovic, Brankica;
Bozovic, Olga;
Hamm, Peter

Publication type:

Article

The Interface between BCR-ABL-Dependent and -Independent Resistance Signaling Pathways in ChronicMyeloid Leukemia.

Published in:

Leukemia Research & Treatment, 2012, p. 1, doi. 10.1155/2012/671702

By:

de Moraes, Gabriela Nestal;
Souza, Paloma Silva;
de Faria Costas, Fernanda Casal;
Vasconcelos, Flavia Cunha;
Souza Reis, Flaviana Ruade;
Maia, Raquel Ciuvalschi

Publication type:

Article

Drugging the Ral GTPase.

Published in:

Small GTPases, 2015, v. 6, n. 3, p. 157, doi. 10.1080/21541248.2015.1018403

By:

Yan, Chao;
Jones, David NM;
Theodorescu, Dan

Publication type:

Article

Erratum to: Modifications of Diflunisal and Meclofenamate Carboxyl Groups Affect Their Allosteric Effects on GABA Receptor Ligand Binding.

Published in:

2014

By:

Uusi-Oukari, Mikko;
Vähätalo, Laura;
Liljeblad, Arto

Publication type:

Erratum

Modifications of Diflunisal and Meclofenamate Carboxyl Groups Affect Their Allosteric Effects on GABA Receptor Ligand Binding.

Published in:

Neurochemical Research, 2014, v. 39, n. 7, p. 1183, doi. 10.1007/s11064-014-1351-x

By:

Uusi-Oukari, Mikko;
Vähätalo, Laura;
Liljeblad, Arto

Publication type:

Article

Molecular mechanism of methyl-dependent and spatial-specific DNA recognition of c-Jun homodimer.

Published in:

Journal of Molecular Modeling, 2021, v. 27, n. 8, p. 1, doi. 10.1007/s00894-021-04840-y

By:

Bie, Li-Hua;
Fei, Jun-Wen;
Gao, Jun

Publication type:

Article

The neural γ2α1β2α1β2 gamma amino butyric acid ion channel receptor: structural analysis of the effects of the ivermectin molecule and disulfide bridges.

Published in:

Journal of Molecular Modeling, 2018, v. 24, n. 8, p. 1, doi. 10.1007/s00894-018-3739-z

By:

Ayan, Meral;
Essiz, Sebnem

Publication type:

Article

Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization.

Published in:

PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 9, p. 347, doi. 10.1093/protein/gzw033

By:

Chendi Zhan;
Ruxi Qi;
Guanghong Wei;
Guven-Maiorov, Emine;
Nussinov, Ruth;
Buyong Ma

Publication type:

Article

A geometry-based generic predictor for catalytic and allosteric sites.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 4, p. 405, doi. 10.1093/protein/gzq115

By:

Mitternacht, Simon;
Berezovsky, Igor N.

Publication type:

Article

Evolving Lac repressor for enhanced inducibility.

Published in:

PEDS: Protein Engineering, Design & Selection, 2009, v. 22, n. 2, p. 53, doi. 10.1093/protein/gzn069

By:

Lakshmi, O. Satya;
Rao, N. M.

Publication type:

Article

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response.

Published in:

EMBO Journal, 2008, v. 27, n. 15, p. 2135, doi. 10.1038/emboj.2008.126

By:

Soulat, Didier;
Bürckstümmer, Tilmann;
Westermayer, Sandra;
Goncalves, Adriana;
Bauch, Angela;
Stefanovic, Adrijana;
Hantschel, Oliver;
Bennett, Keiryn L;
Decker, Thomas;
Superti-Furga, Giulio

Publication type:

Article

Efficacy of mGlu2-positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 3, p. 484, doi. 10.1111/epi.13659

By:

Metcalf, Cameron S.;
Klein, Brian D.;
Smith, Misty D.;
Pruess, Tim;
Ceusters, Marc;
Lavreysen, Hilde;
Pype, Stefan;
Van Osselaer, Nancy;
Twyman, Roy;
White, H. Steve

Publication type:

Article

Unwinding the Wnt action of casein kinase 1.

Published in:

Cell Research, 2013, v. 23, n. 6, p. 737, doi. 10.1038/cr.2013.51

By:

Yim, Daniel GR;
Virshup, David M

Publication type:

Article

Membrane redistributions through multi-intercellular exchanges and serial trogocytosis.

Published in:

Cell Research, 2010, v. 20, n. 11, p. 1239, doi. 10.1038/cr.2010.136

By:

Alegre, Estibaliz;
Kiave-Yune HoWangYin;
Favier, Benoit;
Baudhuin, Jeremy;
Lesport, Emilie;
Daouya, Marina;
Gonzalez, Alvaro;
Carosella, Edgardo D;
LeMaoult, Joel

Publication type:

Article

Investigation of allosteric coupling in human β2-adrenergic receptor in the presence of intracellular loop 3.

Published in:

BMC Structural Biology, 2016, v. 16, p. 1, doi. 10.1186/s12900-016-0061-9

By:

Ozgur, Canan;
Doruker, Pemra;
Akten, E. Demet

Publication type:

Article

Exploring allosteric coupling in the α-subunit of Heterotrimeric G proteins using evolutionary and ensemble-based approaches.

Published in:

BMC Structural Biology, 2008, v. 8, p. 1, doi. 10.1186/1472-6807-8-23

By:

Sayar, Kemal;
Uğur, Özlem;
Tong Liu;
Hilser, Vincent J.;
Onaran, Ongun

Publication type:

Article

The genotype‐phenotype landscape of an allosteric protein.

Published in:

Molecular Systems Biology, 2021, v. 17, n. 12, p. 1, doi. 10.15252/msb.202110847

By:

Tack, Drew S;
Tonner, Peter D;
Pressman, Abe;
Olson, Nathan D;
Levy, Sasha F;
Romantseva, Eugenia F;
Alperovich, Nina;
Vasilyeva, Olga;
Ross, David

Publication type:

Article

The genotype‐phenotype landscape of an allosteric protein.

Published in:

Molecular Systems Biology, 2021, v. 17, n. 3, p. 1, doi. 10.15252/msb.202010179

By:

Tack, Drew S;
Tonner, Peter D;
Pressman, Abe;
Olson, Nathan D;
Levy, Sasha F;
Romantseva, Eugenia F;
Alperovich, Nina;
Vasilyeva, Olga;
Ross, David

Publication type:

Article

Markov propagation of allosteric effects in biomolecular systems: application to GroEL–GroES.

Published in:

Molecular Systems Biology, 2006, v. 2, n. 1, p. E1, doi. 10.1038/msb4100075

By:

Chennubhotla, Chakra;
Bahar, Ivet

Publication type:

Article

Residues crucial for maintaining short paths in network communication mediate signaling in proteins.

Published in:

Molecular Systems Biology, 2006, v. 2, n. 1, p. E1, doi. 10.1038/msb4100063

By:

del Sol, Antonio;
Fujihashi, Hirotomo;
Amoros, Dolors;
Nussinov, Ruth

Publication type:

Article

Bay41-4109-induced aberrant polymers of hepatitis b capsid proteins are removed via STUB1-promoted p62-mediated macroautophagy.

Published in:

PLoS Pathogens, 2022, v. 18, n. 1, p. 1, doi. 10.1371/journal.ppat.1010204

By:

Lin, Jiacheng;
Yin, Limin;
Xu, Xia-Zhen;
Sun, He-Chen;
Huang, Zhi-Hua;
Ni, Xue-Yun;
Chen, Yan;
Lin, Xu

Publication type:

Article

Amino acid residues at core protein dimer-dimer interface modulate multiple steps of hepatitis B virus replication and HBeAg biogenesis.

Published in:

PLoS Pathogens, 2021, v. 17, n. 11, p. 1, doi. 10.1371/journal.ppat.1010057

By:

Liu, Hui;
Cheng, Junjun;
Viswanathan, Usha;
Chang, Jinhong;
Lu, Fengmin;
Guo, Ju-Tao

Publication type:

Article

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling.

Published in:

PLoS Computational Biology, 2018, v. 14, n. 9, p. 1, doi. 10.1371/journal.pcbi.1006458

By:

Pantsar, Tatu;
Rissanen, Sami;
Dauch, Daniel;
Laitinen, Tuomo;
Vattulainen, Ilpo;
Poso, Antti

Publication type:

Article

Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response.

Published in:

PLoS Computational Biology, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.pcbi.1006228

By:

Tee, Wei-Ven;
Guarnera, Enrico;
Berezovsky, Igor N.

Publication type:

Article

Are there physicochemical differences between allosteric and competitive ligands?

Published in:

PLoS Computational Biology, 2017, v. 13, n. 11, p. 1, doi. 10.1371/journal.pcbi.1005813

By:

Smith, Richard D.;
Lu, Jing;
Carlson, Heather A.

Publication type:

Article

Covalent fragment-based ligand screening approaches for identification of novel ubiquitin proteasome system modulators.

Published in:

Biological Chemistry, 2022, v. 403, n. 4, p. 391, doi. 10.1515/hsz-2021-0396

By:

Rothweiler, Elisabeth M.;
Brennan, Paul E.;
Huber, Kilian V. M.

Publication type:

Article

Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 56, doi. 10.1038/nsmb.2705

By:

Alexander, Nathan S;
Preininger, Anita M;
Kaya, Ali I;
Stein, Richard A;
Hamm, Heidi E;
Meiler, Jens

Publication type:

Article

Allosteric control of the ribosome by small-molecule antibiotics.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 957, doi. 10.1038/nsmb.2360

By:

Wang, Leyi;
Pulk, Arto;
Wasserman, Michael R;
Feldman, Michael B;
Altman, Roger B;
Doudna Cate, Jamie H;
Blanchard, Scott C

Publication type:

Article

Enhanced interrogation: emerging strategies for cell signaling inhibition.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 646, doi. 10.1038/nsmb0610-646

By:

Huang, Rong;
Martinez-Ferrando, Isabel;
Cole, Philip A.

Publication type:

Article

Membrane-dependent signal integration by the Ras activator Son of sevenless.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 452, doi. 10.1038/nsmb.1418

By:

Gureasko, Jodi;
Galush, William J.;
Boykevisch, Sean;
Sondermann, Holger;
Bar-Sagi, Dafna;
Groves, Jay T.;
Kuriyan, John

Publication type:

Article

Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 5, p. 432, doi. 10.1038/nsmb1236

By:

Reissmann, Stefanie;
Parnot, Charles;
Booth, Christopher R;
Wah Chiu;
Frydman, Judith

Publication type:

Article

Conformational restriction blocks glutamate receptor desensitization.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 12, p. 1120, doi. 10.1038/nsmb1178

By:

Weston, Matthew C.;
Schuck, Peter;
Ghosal, Alokesh;
Rosenmund, Christian;
Mayer, Mark L.

Publication type:

Article

Coordination of microbial metabolism.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 5, p. 327, doi. 10.1038/nrmicro3238

By:

Chubukov, Victor;
Gerosa, Luca;
Kochanowski, Karl;
Sauer, Uwe

Publication type:

Article

Characterization of chloroplastic thioredoxin dependent glutathione peroxidase like protein in Euglena gracilis: biochemical and functional perspectives.

Published in:

Bioscience, Biotechnology & Biochemistry, 2024, v. 88, n. 9, p. 1034, doi. 10.1093/bbb/zbae087

By:

Raihan, Md Topu;
Tanaka, Yasuhiro;
Ishikawa, Takahiro

Publication type:

Article

Recent advances in the development of allosteric protein tyrosine phosphatase inhibitors for drug discovery.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 3, p. 1064, doi. 10.1002/med.21871

By:

Elhassan, Reham M.;
Hou, Xuben;
Fang, Hao

Publication type:

Article

Systematic Analysis of Covalent and Allosteric Protein Kinase Inhibitors.

Published in:

Molecules, 2023, v. 28, n. 15, p. 5805, doi. 10.3390/molecules28155805

By:

Xerxa, Elena;
Laufkötter, Oliver;
Bajorath, Jürgen

Publication type:

Article

The Motion Paradigm of Pre-Dock Zearalenone Hydrolase Predictions with Molecular Dynamics and the Docking Phase with Umbrella Sampling.

Published in:

Molecules, 2023, v. 28, n. 11, p. 4545, doi. 10.3390/molecules28114545

By:

Hong, Xi-Zhi;
Han, Zheng-Gang;
Yang, Jiang-Ke;
Liu, Yi-Han

Publication type:

Article

Design, Synthesis, and Evaluation of a Set of Carboxylic Acid and Phosphate Prodrugs Derived from HBV Capsid Protein Allosteric Modulator NVR 3-778.

Published in:

Molecules, 2022, v. 27, n. 18, p. 5987, doi. 10.3390/molecules27185987

By:

Ji, Xiangkai;
Jiang, Xiangyi;
Kobayashi, Chisa;
Ren, Yujie;
Hu, Lide;
Gao, Zhen;
Kang, Dongwei;
Jia, Ruifang;
Zhang, Xujie;
Zhao, Shujie;
Watashi, Koichi;
Liu, Xinyong;
Zhan, Peng

Publication type:

Article

Inositol Pyrophosphates: Signaling Molecules with Pleiotropic Actions in Mammals.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2208, doi. 10.3390/molecules25092208

By:

Lee, Seulgi;
Kim, Min-Gyu;
Ahn, Hyoungjoon;
Kim, Seyun;
Vucenik, Ivana

Publication type:

Article

Small Molecule Targeting of Protein-Protein Interactions through Allosteric Modulation of Dynamics.

Published in:

Molecules, 2015, v. 20, n. 9, p. 16435, doi. 10.3390/molecules200916435

By:

Cossins, Benjamin P.;
Lawson, Alastair D. G.

Publication type:

Article