Works matching DE "ORGANIC cation transporters"

Results: 478

The organic cation transporter 3 (OCT3) as molecular target of psychotropic drugs: transport characteristics and acute regulation of cloned murine OCT3.

Published in:

Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 3, p. 517, doi. 10.1007/s00424-013-1335-8

By:

Massmann, Vivian;
Edemir, Bayram;
Schlatter, Eberhard;
Al-Monajjed, Rouvier;
Harrach, Saliha;
Klassen, Philipp;
Holle, Svenja;
Sindic, Aleksandra;
Dobrivojevic, Marina;
Pavenstädt, Hermann;
Ciarimboli, Giuliano

Publication type:

Article

Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter.

Published in:

Pflügers Archiv: European Journal of Physiology, 2013, v. 465, n. 12, p. 1701, doi. 10.1007/s00424-013-1307-z

By:

Schophuizen, Carolien M. S.;
Wilmer, Martijn J.;
Jansen, Jitske;
Gustavsson, Lena;
Hilgendorf, Constanze;
Hoenderop, Joost G. J.;
van den Heuvel, Lambert P.;
Masereeuw, Rosalinde

Publication type:

Article

Crystal and molecular structure of diphenyliodonium diiodobromide.

Published in:

Russian Journal of General Chemistry, 2012, v. 82, n. 11, p. 1842, doi. 10.1134/S1070363212110205

By:

Chernov'yants, M.;
Burykin, I.;
Starikova, Z.;
Rostovskaya, A.

Publication type:

Article

First Case Report of Primary Carnitine Deficiency Manifested as Intellectual Disability and Autism Spectrum Disorder.

Published in:

Brain Sciences (2076-3425), 2019, v. 9, n. 6, p. 137, doi. 10.3390/brainsci9060137

By:

Guevara-Campos, José;
González-Guevara, Lucía;
Guevara-González, José;
Cauli, Omar

Publication type:

Article

Inflammation and Organic Cation Transporters Novel (OCTNs).

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 4, p. 392, doi. 10.3390/biom14040392

By:

Pochini, Lorena;
Galluccio, Michele;
Console, Lara;
Scalise, Mariafrancesca;
Eberini, Ivano;
Indiveri, Cesare

Publication type:

Article

Stereoselectivity in the Membrane Transport of Phenylethylamine Derivatives by Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 10, p. N.PAG, doi. 10.3390/biom12101507

By:

Gebauer, Lukas;
Rafehi, Muhammad;
Brockmöller, Jürgen

Publication type:

Article

Structural basis of organic cation transporter-3 inhibition.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34284-8

By:

Khanppnavar, Basavraj;
Maier, Julian;
Herborg, Freja;
Gradisch, Ralph;
Lazzarin, Erika;
Luethi, Dino;
Yang, Jae-Won;
Qi, Chao;
Holy, Marion;
Jäntsch, Kathrin;
Kudlacek, Oliver;
Schicker, Klaus;
Werge, Thomas;
Gether, Ulrik;
Stockner, Thomas;
Korkhov, Volodymyr M.;
Sitte, Harald H.

Publication type:

Article

Structural basis of organic cation transporter-3 inhibition.

Published in:

Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-34284-8

By:

Khanppnavar, Basavraj;
Maier, Julian;
Herborg, Freja;
Gradisch, Ralph;
Lazzarin, Erika;
Luethi, Dino;
Yang, Jae-Won;
Qi, Chao;
Holy, Marion;
Jäntsch, Kathrin;
Kudlacek, Oliver;
Schicker, Klaus;
Werge, Thomas;
Gether, Ulrik;
Stockner, Thomas;
Korkhov, Volodymyr M.;
Sitte, Harald H.

Publication type:

Article

Enhanced stability of low temperature processed perovskite solar cells via augmented polaronic intensity of hole transporting layer.

Published in:

Physica Status Solidi - Rapid Research Letters, 2016, v. 10, n. 12, p. 882, doi. 10.1002/pssr.201600315

By:

Arafat Mahmud, Md.;
Kumar Elumalai, NaveEN;
Baishakhi Upama, Mushfika;
Wang, Dian;
Haque, Faiazul;
Wright, Matthew;
Howe Chan, Kah;
Xu, ChENg;
Uddin, Ashraf

Publication type:

Article

Drug-Drug Interaction Between Fluconazole and Vancomycin: A Case Report.

Published in:

2024

By:

Lozano, Roberto;
Bona, Carina;
Fresquet, Raquel

Publication type:

Case Study

High performance liquid chromatography-mass spectrometry/mass spectrometry (HPLC-MS/MS) analysis of transmembrane transport characteristics of nuciferine in Caco-2 cells.

Published in:

Journal of Biotech Research, 2021, v. 12, p. 144

By:

Xiaochen Dong;
Shengnan Zhu;
Zonghua Dong;
Luting Ye;
Mingqi Liu;
Jin Zhao;
Jian Ge

Publication type:

Article

A dense convolutional neural network for hyperspectral image classification.

Published in:

Remote Sensing Letters, 2019, v. 10, n. 1, p. 59, doi. 10.1080/2150704X.2018.1526424

By:

Zhi, Lu;
Yu, Xuchu;
Liu, Bing;
Wei, Xiangpo

Publication type:

Article

Genetic Variants of SLC22A1 rs628031 and rs622342 and Glycemic Control in T2DM Patients from Northern Mexico.

Published in:

Genes, 2025, v. 16, n. 2, p. 139, doi. 10.3390/genes16020139

By:

Moreno-González, Janette G.;
Reza-López, Sandra A.;
González-Rodríguez, Everardo;
Siqueiros-Cendón, Tania Samanta;
Escareño Contreras, Alfonso;
Rascón-Cruz, Quintín;
Leal-Berumen, Irene

Publication type:

Article

Identification of Novel Intronic SNPs in Transporter Genes Associated with Metformin Side Effects.

Published in:

Genes, 2023, v. 14, n. 8, p. 1609, doi. 10.3390/genes14081609

By:

Schweighofer, Natascha;
Strasser, Moritz;
Obermayer, Anna;
Trummer, Olivia;
Sourij, Harald;
Sourij, Caren;
Obermayer-Pietsch, Barbara

Publication type:

Article

Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin.

Published in:

Expert Review of Clinical Pharmacology, 2022, v. 15, n. 9, p. 1107, doi. 10.1080/17512433.2022.2118714

By:

Li, Shaoqian;
Xu, Bo;
Fan, Shangzhi;
Kang, Bo;
Deng, Lijing;
Chen, Danjun;
Yang, Bo;
Tang, Fan;
He, Zunbo;
Xue, Yong;
Zhou, Jie-Can

Publication type:

Article

Atomistic description of the OCTN1 recognition mechanism via in silico methods.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0304512

By:

Ben Mariem, Omar;
Palazzolo, Luca;
Torre, Beatrice;
Wei, Yao;
Bianchi, Davide;
Guerrini, Uliano;
Laurenzi, Tommaso;
Saporiti, Simona;
De Fabiani, Emma;
Pochini, Lorena;
Indiveri, Cesare;
Eberini, Ivano

Publication type:

Article

The Mechanotransduction Channel and Organic Cation Transporter Are Critical for Cisplatin Ototoxicity in Murine Hair Cells.

Published in:

Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.835448

By:

Li, Jinan;
Liu, Chang;
Kaefer, Samuel;
Youssef, Mariam;
Zhao, Bo

Publication type:

Article

Fine mapping of a thrips resistance QTL in Capsicum and the role of diterpene glycosides in the underlying mechanism.

Published in:

Theoretical & Applied Genetics, 2021, v. 134, n. 5, p. 1557, doi. 10.1007/s00122-021-03790-6

By:

van Haperen, Pauline;
Voorrips, Roeland E.;
van Kaauwen, Martijn;
van Eekelen, Henriëtte D. L. M.;
de Vos, Ric C. H.;
van Loon, Joop J. A.;
Vosman, Ben

Publication type:

Article

Kidney Transporters and Drug-Induced Injury in Drug Development.

Published in:

2020

By:

Radi, Zaher A.

Publication type:

Literature Review

Modulating the Activity of the Human Organic Cation Transporter 2 Emerges as a Potential Strategy to Mitigate Unwanted Toxicities Associated with Cisplatin Chemotherapy.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2922, doi. 10.3390/ijms25052922

By:

Hucke, Anna;
Kantauskaite, Marta;
Köpp, Tim N.;
Wehe, Christoph A.;
Karst, Uwe;
Nedvetsky, Pavel I.;
Ciarimboli, Giuliano

Publication type:

Article

Regulation of Transporters for Organic Cations by High Glucose.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 14051, doi. 10.3390/ijms241814051

By:

Steinbüchel, Martin;
Menne, Johannes;
Schröter, Rita;
Neugebauer, Ute;
Schlatter, Eberhard;
Ciarimboli, Giuliano

Publication type:

Article

Role of Mouse Organic Cation Transporter 2 for Nephro- and Peripheral Neurotoxicity Induced by Chemotherapeutic Treatment with Cisplatin.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 14, p. 11486, doi. 10.3390/ijms241411486

By:

Hucke, Anna;
Schröter, Rita;
Ceresa, Cecilia;
Chiorazzi, Alessia;
Canta, Annalisa;
Semperboni, Sara;
Marmiroli, Paola;
Cavaletti, Guido;
Gess, Burkhard;
Ciarimboli, Giuliano

Publication type:

Article

Overcoming Biological Barriers: Importance of Membrane Transporters in Homeostasis, Disease and Disease Treatment.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7212, doi. 10.3390/ijms24087212

By:

Ciarimboli, Giuliano

Publication type:

Article

The Role of Organic Cation Transporters in the Pharmacokinetics, Pharmacodynamics and Drug–Drug Interactions of Tyrosine Kinase Inhibitors.

Published in:

2023

By:

Xiu, Fangrui;
Rausch, Magdalena;
Gai, Zhibo;
Su, Shanshan;
Wang, Shijun;
Visentin, Michele

Publication type:

Literature Review

Exacerbation of Cisplatin Cellular Toxicity by Regulation of the Human Organic Cation Transporter 2 through Angiotensin II.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15866, doi. 10.3390/ijms232415866

By:

Kantauskaite, Marta;
Hucke, Anna;
Snieder, Beatrice;
Ciarimboli, Giuliano

Publication type:

Article

Investigations with Drugs and Pesticides Revealed New Species- and Substrate-Dependent Inhibition by Elacridar and Imazalil in Human and Mouse Organic Cation Transporter OCT2.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15795, doi. 10.3390/ijms232415795

By:

Kuehne, Annett;
Floerl, Saskia;
Hagos, Yohannes

Publication type:

Article

Interaction of Masitinib with Organic Cation Transporters.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14189, doi. 10.3390/ijms232214189

By:

Harrach, Saliha;
Haag, Jasmin;
Steinbüchel, Martin;
Schröter, Rita;
Neugebauer, Ute;
Bertrand, Jessica;
Ciarimboli, Giuliano

Publication type:

Article

Molecular Mechanisms of Cerebrovascular Diseases.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7161, doi. 10.3390/ijms23137161

By:

Andjelkovic, Anuska V.;
Keep, Richard F.;
Wang, Michael M.

Publication type:

Article

Physiology, Biochemistry and Pharmacology of Transporters for Organic Cations 2.0.

Published in:

2022

By:

Ciarimboli, Giuliano

Publication type:

Editorial

Cloning and Functional Characterization of Dog OCT1 and OCT2: Another Step in Exploring Species Differences in Organic Cation Transporters.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 5100, doi. 10.3390/ijms23095100

By:

Meyer, Marleen Julia;
Falk, Simon;
Römer, Sarah;
Prinzinger, Clarissa;
Tacke, Sabine;
Geyer, Joachim;
Simm, Stefan;
Tzvetkov, Mladen Vassilev

Publication type:

Article

Relationships between Inhibition, Transport and Enhanced Transport via the Organic Cation Transporter 1.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2007, doi. 10.3390/ijms23042007

By:

Jensen, Ole;
Gebauer, Lukas;
Brockmöller, Jürgen;
Dücker, Christof

Publication type:

Article

OCTN1: A Widely Studied but Still Enigmatic Organic Cation Transporter Linked to Human Pathology and Drug Interactions.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 914, doi. 10.3390/ijms23020914

By:

Pochini, Lorena;
Galluccio, Michele;
Scalise, Mariafrancesca;
Console, Lara;
Pappacoda, Gilda;
Indiveri, Cesare

Publication type:

Article

Expression and Functional Contribution of Different Organic Cation Transporters to the Cellular Uptake of Doxorubicin into Human Breast Cancer and Cardiac Tissue.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 255, doi. 10.3390/ijms23010255

By:

Otter, Marcus;
Csader, Susanne;
Keiser, Markus;
Oswald, Stefan

Publication type:

Article

Role of Organic Cation Transporter 3 and Plasma Membrane Monoamine Transporter in the Rewarding Properties and Locomotor Sensitizing Effects of Amphetamine in Male andFemale Mice.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13420, doi. 10.3390/ijms222413420

By:

Clauss, Nikki J.;
Koek, Wouter;
Daws, Lynette C.

Publication type:

Article

SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13407, doi. 10.3390/ijms222413407

By:

Zhang, Patrick;
Azad, Priti;
Engelhart, Darcy C.;
Haddad, Gabriel G.;
Nigam, Sanjay K.

Publication type:

Article

Interaction Profiles of Central Nervous System Active Drugs at Human Organic Cation Transporters 1–3 and Human Plasma Membrane Monoamine Transporter.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12995, doi. 10.3390/ijms222312995

By:

Angenoorth, Thomas J. F.;
Stankovic, Stevan;
Niello, Marco;
Holy, Marion;
Brandt, Simon D.;
Sitte, Harald H.;
Maier, Julian

Publication type:

Article

Substrate-Dependent Trans -Stimulation of Organic Cation Transporter 2 Activity.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12926, doi. 10.3390/ijms222312926

By:

Lefèvre, Charles R.;
Le Vée, Marc;
Gaubert, Sophie;
Jouan, Elodie;
Bruyere, Arnaud;
Moreau, Caroline;
Fardel, Olivier

Publication type:

Article

Overlap and Specificity in the Substrate Spectra of Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12816, doi. 10.3390/ijms222312816

By:

Gebauer, Lukas;
Jensen, Ole;
Neif, Maria;
Brockmöller, Jürgen;
Dücker, Christof

Publication type:

Article

Utilizing an Amino Acid Scaffold to Construct Heteroditopic Receptors Capable of Interacting with Salts under Interfacial Conditions.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10754, doi. 10.3390/ijms221910754

By:

Jagleniec, Damian;
Walczak, Natalia;
Dobrzycki, Łukasz;
Romański, Jan

Publication type:

Article

Properties of Transport Mediated by the Human Organic Cation Transporter 2 Studied in a Polarized Three-Dimensional Epithelial Cell Culture Model.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9658, doi. 10.3390/ijms22179658

By:

Koepp, Tim N.;
Tokaj, Alexander;
Nedvetsky, Pavel I.;
Conchon Costa, Ana Carolina;
Snieder, Beatrice;
Schröter, Rita;
Ciarimboli, Giuliano

Publication type:

Article

Differential Serotonin Uptake Mechanisms at the Human Maternal–Fetal Interface.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 7807, doi. 10.3390/ijms22157807

By:

Baković, Petra;
Kesić, Maja;
Perić, Maja;
Bečeheli, Ivona;
Horvatiček, Marina;
George, Meekha;
Čičin-Šain, Lipa;
Desoye, Gernot;
Wadsack, Christian;
Panzenboeck, Ute;
Štefulj, Jasminka

Publication type:

Article

In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6439, doi. 10.3390/ijms22126439

By:

George, Blessy;
Wen, Xia;
Jaimes, Edgar A.;
Joy, Melanie S.;
Aleksunes, Lauren M.

Publication type:

Article

Incorporation of Sulfonamide Moiety into Biguanide Scaffold Results in Apoptosis Induction and Cell Cycle Arrest in MCF-7 Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5642, doi. 10.3390/ijms22115642

By:

Markowicz-Piasecka, Magdalena;
Sadowski, Karol;
Huttunen, Johanna;
Sikora, Joanna;
Huttunen, Kristiina M.

Publication type:

Article

Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 3821, doi. 10.3390/ijms22083821

By:

Enge, Anne-Margarethe;
Kaltner, Florian;
Gottschalk, Christoph;
Braeuning, Albert;
Hessel-Pras, Stefanie

Publication type:

Article

Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations.

Published in:

2021

By:

Ciarimboli, Giuliano

Publication type:

Editorial

The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7431, doi. 10.3390/ijms21197431

By:

Di Cristo, Francesca;
Calarco, Anna;
Digilio, Filomena Anna;
Sinicropi, Maria Stefania;
Rosano, Camillo;
Galderisi, Umberto;
Melone, Mariarosa Anna Beatrice;
Saturnino, Carmela;
Peluso, Gianfranco

Publication type:

Article

PPAR-α Deletion Attenuates Cisplatin Nephrotoxicity by Modulating Renal Organic Transporters MATE-1 and OCT-2.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7416, doi. 10.3390/ijms21197416

By:

Freitas-Lima, Leandro Ceotto;
Budu, Alexandre;
Arruda, Adriano Cleis;
Perilhão, Mauro Sérgio;
Barrera-Chimal, Jonatan;
Araujo, Ronaldo Carvalho;
Estrela, Gabriel Rufino

Publication type:

Article

Functional and Pharmacological Comparison of Human, Mouse, and Rat Organic Cation Transporter 1 toward Drug and Pesticide Interaction.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6871, doi. 10.3390/ijms21186871

By:

Floerl, Saskia;
Kuehne, Annett;
Hagos, Yohannes

Publication type:

Article

The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6627, doi. 10.3390/ijms21186627

By:

Zazuli, Zulfan;
Duin, Naut J. C. B.;
Jansen, Katja;
Vijverberg, Susanne J. H.;
Maitland-van der Zee, Anke H.;
Masereeuw, Rosalinde

Publication type:

Article

Tofacitinib and Baricitinib Are Taken up by Different Uptake Mechanisms Determining the Efficacy of Both Drugs in RA.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6632, doi. 10.3390/ijms21186632

By:

Amrhein, Jan;
Drynda, Susanne;
Schlatt, Lukas;
Karst, Uwe;
Lohmann, Christoph H.;
Ciarimboli, Giuliano;
Bertrand, Jessica

Publication type:

Article