Works matching Motor neurons

Results: 5000

Supraphysiological expression of survival motor neuron protein from an adenovirus vector does not adversely affect cell function.

Published in:

Biochemistry & Cell Biology, 2013, v. 91, n. 4, p. 252, doi. 10.1139/bcb-2012-0094

By:

Goulet, Benoit B.;
McFall, Emily R.;
Wong, Carmen M.;
Kothary, Rashmi;
Parks, Robin J.

Publication type:

Article

Motor Band Sign in Motor Neuron Disease: A Marker for Upper Motor Neuron Involvement.

Published in:

Canadian Journal of Neurological Sciences, 2023, v. 50, n. 3, p. 373, doi. 10.1017/cjn.2022.52

By:

Chung, Hee Sahng;
Melkus, Gerd;
Bourque, Pierre;
Chakraborty, Santanu

Publication type:

Article

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.

Published in:

PLoS Genetics, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pgen.1006680

By:

Kline, Rachel A.;
Kaifer, Kevin A.;
Osman, Erkan Y.;
Carella, Francesco;
Tiberi, Ariana;
Ross, Jolill;
Pennetta, Giuseppa;
Lorson, Christian L.;
Murray, Lyndsay M.

Publication type:

Article

Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy.

Published in:

Acta Neuropathologica, 2011, v. 121, n. 4, p. 509, doi. 10.1007/s00401-011-0797-z

By:

Geser, Felix;
Stein, Beth;
Partain, Michael;
Elman, Lauren B.;
McCluskey, Leo F.;
Xie, Sharon X.;
Van Deerlin, Vivianna M.;
Kwong, Linda K.;
Lee, Virginia M.-Y.;
Trojanowski, John Q.

Publication type:

Article

Role of EphA4 in Mediating Motor Neuron Death in MND.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9430, doi. 10.3390/ijms22179430

By:

Zhao, Jing;
Stevens, Claire H.;
Boyd, Andrew W.;
Ooi, Lezanne;
Bartlett, Perry F.

Publication type:

Article

Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy.

Published in:

Journal of Anatomy, 2016, v. 228, n. 3, p. 443, doi. 10.1111/joa.12419

By:

Powis, Rachael A.;
Gillingwater, Thomas H.

Publication type:

Article

Superconditioning TMS for examining upper motor neuron function in MND.

Published in:

Experimental Brain Research, 2019, v. 237, n. 8, p. 2087, doi. 10.1007/s00221-019-05573-4

By:

Calancie, Blair;
Young, Eufrosina;
Watson, Mary Lou;
Wang, Dongliang;
Alexeeva, Natalia

Publication type:

Article

Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy.

Published in:

Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0806-3

By:

Rehorst, Wiebke A.;
Thelen, Maximilian P.;
Nolte, Hendrik;
Türk, Clara;
Cirak, Sebahattin;
Peterson, Jonathan M.;
Wong, G. William;
Wirth, Brunhilde;
Krüger, Marcus;
Winter, Dominic;
Kye, Min Jeong

Publication type:

Article

Targeting the full length of the motor end plate regions in the mouse forelimb increases the uptake of Fluoro-Gold into corresponding spinal cord motor neurons.

Published in:

Frontiers in Neurology, 2013, v. 4, p. 1, doi. 10.3389/fneur.2013.00058

By:

Tosolini, Andrew Paul;
Mohan, Rahul;
Morris, Renée

Publication type:

Article

PuraMatrix hydrogel enhances the expression of motor neuron progenitor marker and improves adhesion and proliferation of motor neuron-like cells.

Published in:

Iranian Journal of Basic Medical Sciences, 2020, v. 23, n. 4, p. 431, doi. 10.22038/ijbms.2020.39797.9434

By:

Darvishi, Marzieh;
Hamidabadi, Hatef Ghasemi;
Negah, Sajad Sahab;
Moayeri, Ardeshir;
Tiraihi, Taki;
Mirnajafi-Zadeh, Javad;
Jahan-Abad, Ali Jahanbazi;
Shojaei, Amir

Publication type:

Article

Homozygous Survival Motor Neuron 2 Gene Deletion and Sporadic Lower Motor Neuron Disease in Children: Case Report and Literature Review.

Published in:

2013

By:

Liping, Lu;
Hongwei, Ma;
Lin, Wang

Publication type:

Case Study

Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study.

Published in:

Brain Pathology, 2025, v. 35, n. 1, p. 1, doi. 10.1111/bpa.13286

By:

Murakami, Aya;
Koga, Shunsuke;
Fujioka, Shinsuke;
White, Adrianna E.;
Bieniek, Kevin F.;
Sekiya, Hiroaki;
DeJesus‐Hernandez, Mariely;
Finch, NiCole A.;
van Blitterswijk, Marka;
Nakamura, Masataka;
Tsuboi, Yoshio;
Murray, Melissa E.;
Wszolek, Zbigniew K.;
Dickson, Dennis W.

Publication type:

Article

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 545, doi. 10.3390/cells12040545

By:

Castellanos-Montiel, María José;
Chaineau, Mathilde;
Franco-Flores, Anna Kristyna;
Haghi, Ghazal;
Carrillo-Valenzuela, Dulce;
Reintsch, Wolfgang E.;
Chen, Carol X.-Q.;
Durcan, Thomas M.

Publication type:

Article

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1127, doi. 10.3390/cells10051127

By:

Cutarelli, Alessandro;
Martínez-Rojas, Vladimir A.;
Tata, Alice;
Battistella, Ingrid;
Rossi, Daniela;
Arosio, Daniele;
Musio, Carlo;
Conti, Luciano;
Pession, Andrea

Publication type:

Article

Highly Efficient Conversion of Motor Neuron-Like NSC-34 Cells into Functional Motor Neurons by Prostaglandin E2.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1741, doi. 10.3390/cells9071741

By:

Nango, Hiroshi;
Kosuge, Yasuhiro;
Sato, Masaki;
Shibukawa, Yoshiyuki;
Aono, Yuri;
Saigusa, Tadashi;
Ito, Yoshihisa;
Ishige, Kumiko

Publication type:

Article

The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord.

Published in:

Cells (2073-4409), 2020, v. 9, n. 2, p. 502, doi. 10.3390/cells9020502

By:

Genc, Baris;
Gozutok, Oge;
Kocak, Nuran;
Ozdinler, P. Hande

Publication type:

Article

Beta-band intermuscular coherence: a novel biomarker of upper motor neuron dysfunction in motor neuron disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 9, p. 2849, doi. 10.1093/brain/aws150

By:

Fisher, Karen M.;
Zaaimi, Boubker;
Williams, Timothy L.;
Baker, Stuart N.;
Baker, Mark R.

Publication type:

Article

Spinal astrocyte dysfunction drives motor neuron loss in late-onset spinal muscular atrophy.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 5, p. 611, doi. 10.1007/s00401-023-02554-4

By:

Schmitt, Linda-Isabell;
David, Christina;
Steffen, Rebecca;
Hezel, Stefanie;
Roos, Andreas;
Schara-Schmidt, Ulrike;
Kleinschnitz, Christoph;
Leo, Markus;
Hagenacker, Tim

Publication type:

Article

Duple-MONDNet: duple deep learning-based mobile net for motor neuron disease identification.

Published in:

Turkish Journal of Medical Sciences, 2025, v. 55, n. 1, p. 140, doi. 10.55730/1300-0144.5952

By:

HELEN, Sony;
JAWHAR, Joseph

Publication type:

Article

The distribution and function of GDE2, a regulator of spinal motor neuron survival, are disrupted in Amyotrophic Lateral Sclerosis.

Published in:

Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01376-x

By:

Westerhaus, Anna;
Joseph, Thea;
Meyers, Alison J.;
Jang, Yura;
Na, Chan Hyun;
Cave, Clinton;
Sockanathan, Shanthini

Publication type:

Article

The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01241-3

By:

Kovacs, Mariángeles;
Alamón, Catalina;
Maciel, Cecilia;
Varela, Valentina;
Ibarburu, Sofía;
Tarragó, Lucas;
King, Peter H.;
Si, Ying;
Kwon, Yuri;
Hermine, Olivier;
Barbeito, Luis;
Trias, Emiliano

Publication type:

Article

Physiological Biomarkers of Upper Motor Neuron Dysfunction in ALS.

Published in:

Brain Sciences (2076-3425), 2024, v. 14, n. 8, p. 760, doi. 10.3390/brainsci14080760

By:

Calma, Aicee Dawn;
van den Bos, Mehdi;
Pavey, Nathan;
Santos Silva, Cláudia;
Menon, Parvathi;
Vucic, Steve

Publication type:

Article

Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS.

Published in:

Brain Sciences (2076-3425), 2021, v. 11, n. 5, p. 578, doi. 10.3390/brainsci11050578

By:

Gozutok, Oge;
Helmold, Benjamin Ryan;
Ozdinler, P. Hande;
Paolone, Giovanna;
Toyooka, Kazuhito

Publication type:

Article

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Brain Sciences (2076-3425), 2021, v. 11, n. 3, p. 369, doi. 10.3390/brainsci11030369

By:

Marques, Christine;
Burg, Thibaut;
Scekic-Zahirovic, Jelena;
Fischer, Mathieu;
Rouaux, Caroline;
Ozdinler, P. Hande;
Turner, Bradley

Publication type:

Article

Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron Diseases: An Overview.

Published in:

Neurodiagnostic Journal, 2015, v. 55, n. 3, p. 180, doi. 10.1080/21646821.2015.1075181

By:

Morris, Jerry

Publication type:

Article

Nonalcoholic Fatty Liver Disease in Patients with Inherited and Sporadic Motor Neuron Degeneration.

Published in:

Genes, 2022, v. 13, n. 6, p. 936, doi. 10.3390/genes13060936

By:

Johnson, Brian;
Kokkinis, Angela;
Gai, Neville;
Shamim, Ejaz A.;
Blackstone, Craig;
Fischbeck, Kenneth H.;
Grunseich, Christopher

Publication type:

Article

A Novel Variant in Superoxide Dismutase 1 Gene (p.V119M) in Als Patients with Pure Lower Motor Neuron Presentation.

Published in:

Genes, 2021, v. 12, n. 10, p. 1544, doi. 10.3390/genes12101544

By:

Ricci, Claudia;
Giannini, Fabio;
Riolo, Giulia;
Bocci, Silvia;
Casali, Stefania;
Battistini, Stefania

Publication type:

Article

Motor neurons and the generation of spinal motor neuron diversity.

Published in:

Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00293

By:

Stifani, Nicolas

Publication type:

Article

Key Disease Mechanisms Linked to Amyotrophic Lateral Sclerosis in Spinal Cord Motor Neurons.

Published in:

Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.825031

By:

Bottero, Virginie;
Santiago, Jose A.;
Quinn, James P.;
Potashkin, Judith A.

Publication type:

Article

MFN2 Deficiency Impairs Mitochondrial Transport and Downregulates Motor Protein Expression in Human Spinal Motor Neurons.

Published in:

Frontiers in Molecular Neuroscience, 2021, v. 14, p. 1, doi. 10.3389/fnmol.2021.727552

By:

Mou, Yongchao;
Dein, Joshua;
Chen, Zhenyu;
Jagdale, Mrunali;
Li, Xue-Jun

Publication type:

Article

Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure.

Published in:

Journal of Neuroscience, 2024, v. 44, n. 16, p. 1, doi. 10.1523/JNEUROSCI.1787-23.2024

By:

Changho Chun;
Jung Hyun Lee;
Bothwell, Mark;
Nghiem, Paul;
Smith, Alec S. T.;
Mack, David L.

Publication type:

Article

A Platform to Understand Amyotrophic Lateral Sclerosis (ALS) and Extend Human Motor Neurons Longevity.

Published in:

International Journal of Morphology, 2019, v. 37, n. 4, p. 1203, doi. 10.4067/s0717-95022019000401203

By:

Cáceres, D. E.;
Torres, F. C.;
Castillo, C. A.;
Maureira, A.;
Franco-Campos, F. A.;
Osorio, M.;
Segovia, R.;
Tapia, J. C.;
Carrasco, M. A.

Publication type:

Article

Nifedipine Ameliorates Cellular Differentiation Defects of Smn-Deficient Motor Neurons and Enhances Neuromuscular Transmission in SMA Mice.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7648, doi. 10.3390/ijms24087648

By:

Tejero, Rocio;
Alsakkal, Mohammad;
Hennlein, Luisa;
Lopez-Cabello, Ana M.;
Jablonka, Sibylle;
Tabares, Lucia

Publication type:

Article

Overexpression of miR-124 in Motor Neurons Plays a Key Role in ALS Pathological Processes.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 6128, doi. 10.3390/ijms22116128

By:

Vaz, Ana Rita;
Vizinha, Daniela;
Morais, Hermes;
Colaço, Ana Rita;
Loch-Neckel, Gecioni;
Barbosa, Marta;
Brites, Dora

Publication type:

Article

Sonic Hedgehog-Gli1 Signaling and Cellular Retinoic Acid Binding Protein 1 Gene Regulation in Motor Neuron Differentiation and Diseases.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 4125, doi. 10.3390/ijms21114125

By:

Lin, Yu-Lung;
Lin, Yi-Wei;
Nhieu, Jennifer;
Zhang, Xiaoyin;
Wei, Li-Na

Publication type:

Article

Complexity of Generating Mouse Models to Study the Upper Motor Neurons: Let Us Shift Focus from Mice to Neurons.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 16, p. 3848, doi. 10.3390/ijms20163848

By:

Genc, Baris;
Gozutok, Oge;
Ozdinler, P. Hande

Publication type:

Article

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation.

Published in:

BMC Molecular & Cell Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12860-021-00343-z

By:

Solomon, Emilia;
Davis-Anderson, Katie;
Hovde, Blake;
Micheva-Viteva, Sofiya;
Harris, Jennifer Foster;
Twary, Scott;
Iyer, Rashi

Publication type:

Article

Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.578143

By:

Lin, Jianing;
Huang, Pian;
Chen, Weineng;
Ye, Chenghui;
Su, Huanxing;
Yao, Xiaoli

Publication type:

Article

Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1<sup>G93A</sup> Mice Reveals Widespread Loss of Androgen Receptor Occurring Early in Spinal Motor Neurons.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.808479

By:

McLeod, Victoria M.;
Chiam, Mathew D. F.;
Perera, Nirma D.;
Lau, Chew L.;
Boon, Wah Chin;
Turner, Bradley J.

Publication type:

Article

Strategy for Treating Motor Neuron Diseases Using a Fusion Protein of Botulinum Toxin Binding Domain and Streptavidin for Viral Vector Access: Work in Progress.

Published in:

Toxins, 2010, v. 2, n. 12, p. 2872, doi. 10.3390/toxins2122872

By:

Drachman, Daniel B.;
Adams, Robert N.;
Balasubramanian, Uma;
Yang Lu

Publication type:

Article

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 13, p. 3811, doi. 10.1523/JNEUROSCI.2396-15.2016

By:

Fallini, Claudia;
Donlin-Asp, Paul G.;
Rouanet, Jeremy P.;
Bassell, Gary J.;
Rossoll, Wilfried

Publication type:

Article

Validity and reliability of an electromyography-based upper limb assessment quantifying selective voluntary motor control in children with upper motor neuron lesions.

Published in:

Science Progress, 2021, p. 1, doi. 10.1177/00368504211008058

By:

Keller, Jeffrey W;
Fahr, Annina;
Balzer, Julia;
Lieber, Jan;
van Hedel, Hubertus JA

Publication type:

Article

Diagnostic value of neurofilaments in differentiating motor neuron disease from multifocal motor neuropathy.

Published in:

Journal of Neurology, 2024, v. 271, n. 7, p. 4441, doi. 10.1007/s00415-024-12355-8

By:

Wohnrade, Camilla;
Seeliger, Tabea;
Gingele, Stefan;
Bjelica, Bogdan;
Skripuletz, Thomas;
Petri, Susanne

Publication type:

Article

Factors impacting trial participation in people with motor neuron disease.

Published in:

Journal of Neurology, 2024, v. 271, n. 1, p. 543, doi. 10.1007/s00415-023-12010-8

By:

Beswick, Emily;
Johnson, Micheala;
Newton, Judith;
Dakin, Rachel;
Stenson, Amy;
Abrahams, Sharon;
Carson, Alan;
Chandran, Siddharthan;
Pal, Suvankar

Publication type:

Article

The impact of upper and lower motor neuron burden on diagnostic certainty, and clinical course of spinal-onset amyotrophic lateral sclerosis: a cluster-based approach.

Published in:

Journal of Neurology, 2023, v. 270, n. 10, p. 4868, doi. 10.1007/s00415-023-11827-7

By:

Milella, Giammarco;
Zoccolella, Stefano;
Giugno, Alessia;
Filardi, Marco;
Urso, Daniele;
Nigro, Salvatore;
Tafuri, Benedetta;
Tamburrino, Ludovica;
Gnoni, Valentina;
Logroscino, Giancarlo

Publication type:

Article

GGC repeat expansions in NOTCH2NLC causing a phenotype of lower motor neuron syndrome.

Published in:

Journal of Neurology, 2022, v. 269, n. 8, p. 4469, doi. 10.1007/s00415-022-11092-0

By:

Zhang, Wei;
Ma, Jing;
Shi, Jiaying;
Huang, Shan;
Zhao, Rongjuan;
Pang, Xiaomin;
Wang, Juan;
Guo, Junhong;
Chang, Xueli

Publication type:

Article

CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement.

Published in:

Biomedicines, 2021, v. 9, n. 11, p. 1623, doi. 10.3390/biomedicines9111623

By:

Simonini, Cecilia;
Zucchi, Elisabetta;
Bedin, Roberta;
Martinelli, Ilaria;
Gianferrari, Giulia;
Fini, Nicola;
Sorarù, Gianni;
Liguori, Rocco;
Vacchiano, Veria;
Mandrioli, Jessica

Publication type:

Article

Subacute combined degeneration of the spinal cord masking motor neuron disease: a case report.

Published in:

2019

By:

Loveland, Paula;
Wong, Aaron;
Vivekanandam, Vinojini;
Lim, Wen Kwang

Publication type:

journal article

p53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.1038276

By:

Buettner, Jannik M.;
Sowoidnich, Leonie;
Gerstner, Florian;
Blanco-Redondo, Beatriz;
Hallermann, Stefan;
Simon, Christian M.

Publication type:

Article

Visual three-dimensional spatial distribution of motor neurons innervating superficial limb muscles in mice.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 01, doi. 10.3389/fncel.2022.904172

By:

Zhidan Qi;
Shuai Han;
Shen Wang;
Xinyi Gu;
Jin Deng;
Chen Huang;
Xiaofeng Yin

Publication type:

Article