Works matching DE "GENE replacement"

Results: 71

De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications.

Published in:

Chromosome Research, 2015, v. 23, n. 1, p. 143, doi. 10.1007/s10577-014-9458-0

By:

Katona, Robert

Publication type:

Article

Construction of the plasmid coding for the expression of the EGFP-M-IL-2(88Arg, 125Ala) fusion protein and the anti-tumor effects exerted by the fusion protein in HeLa-60 cells.

Published in:

Oncology Letters, 2015, v. 9, n. 6, p. 2729, doi. 10.3892/ol.2015.3125

By:

GUANGCAN SHAO;
DONGMENG QIAN;
HAITAO WANG;
ZHIYONG YAN;
MING HU;
TONGMEI WANG;
BIN WANG

Publication type:

Article

Enhanced central memory cluster of differentiation 8+ and tumor antigen-specific T cells in prostate cancer patients receiving repeated in situ adenovirus-mediated suicide gene therapy.

Published in:

Molecular & Clinical Oncology, 2015, v. 3, n. 3, p. 515, doi. 10.3892/mco.2015.519

By:

KUBO, MAKOTO;
SATOH, TAKEFUMI;
TABATA, KEN-ICHI;
TSUMURA, HIDEYASU;
IWAMURA, MASATSUGU;
BABA, SHIRO;
THOMPSON, TIMOTHY C.;
OBATA, FUMIYA

Publication type:

Article

Synthesis-dependent repair of Cpf1-induced double strand DNA breaks enables targeted gene replacement in rice.

Published in:

Journal of Experimental Botany, 2018, v. 69, n. 20, p. 4715, doi. 10.1093/jxb/ery245

By:

Li, Shaoya;
Li, Jingying;
Zhang, Jiahui;
Du, Wenming;
Fu, Jindong;
Sutar, Suhas;
Zhao, Yunde;
Xia, Lanqin

Publication type:

Article

Stable gene replacement in barley by targeted double-strand break induction.

Published in:

Journal of Experimental Botany, 2016, v. 67, n. 5, p. 1433, doi. 10.1093/jxb/erv537

By:

Koichi Watanabe;
Ulrike Breier;
Götz Hensel;
Kumlehn, Jochen;
Ingo Schubert;
Reiss, Bernd

Publication type:

Article

Insights gained from gene therapy in animal models of retGC1 deficiency.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00043

By:

Boye, Shannon E.

Publication type:

Article

A single vector-based strategy for marker-less gene replacement in Synechocystis sp. PCC 6803.

Published in:

Microbial Cell Factories, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2859-13-4

By:

Viola, Stefania;
Rühle, Thilo;
Leister, Dario

Publication type:

Article

Gene replacement and elimination using λRed- and FLP-based tool to re-direct carbon flux in acetogen biocatalyst during continuous CO/H blend fermentation.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 7, p. 749, doi. 10.1007/s10295-013-1279-1

By:

Tyurin, Michael

Publication type:

Article

New strategy to improve efficiency for gene replacement in Klebsiella pneumoniae.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 5, p. 523, doi. 10.1007/s10295-013-1250-1

By:

Wei, Dong;
Sun, Junsong;
Shi, Jiping;
Liu, Pengfu;
Hao, Jian

Publication type:

Article

Red recombinase assisted gene replacement in Klebsiella pneumoniae.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2012, v. 39, n. 8, p. 1219, doi. 10.1007/s10295-012-1117-x

By:

Wei, Dong;
Wang, Min;
Shi, Jiping;
Hao, Jian

Publication type:

Article

Gene Replacement in Mycobacterium chelonae: Application to the Construction of Porin Knock-Out Mutants.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094951

By:

Calado Nogueira de Moura, Vinicius;
Gibbs, Sara;
Jackson, Mary

Publication type:

Article

Deletion of the Pichia pastoris KU70 Homologue Facilitates Platform Strain Generation for Gene Expression and Synthetic Biology.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039720

By:

Naä ätsaari, Laura;
Mistlberger, Beate;
Ruth, Claudia;
Hajek, Tanja;
Hartner, Franz S.;
Glieder, Anton

Publication type:

Article

Caspase Inhibition with XIAP as an Adjunct to AAV Vector Gene-Replacement Therapy: Improving Efficacy and Prolonging the Treatment Window.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037197

By:

Jingyu Yao;
Lin Jia;
Khan, Naheed;
Zheng, Qiong-Duan;
Moncrief, Ashley;
Hauswirth, William W.;
Thompson, Debra A.;
David N. Zacks

Publication type:

Article

Correlation between the linguistic affinity and genetic diversity of Chinese ethnic groups.

Published in:

Journal of Human Genetics, 2013, v. 58, n. 10, p. 686, doi. 10.1038/jhg.2013.79

By:

Sun, Hao;
Zhou, Chi;
Huang, Xiaoqin;
Liu, Shuyuan;
Lin, Keqin;
Yu, Liang;
Huang, Kai;
Chu, Jiayou;
Yang, Zhaoqing

Publication type:

Article

Novel non-contiguous exon duplication in choroideremia.

Published in:

Clinical Genetics, 2018, v. 93, n. 1, p. 144, doi. 10.1111/cge.13021

By:

Edwards, T. L.;
Williams, J.;
Patrício, M. I.;
Simunovic, M. P.;
Shanks, M.;
Clouston, P.;
MacLaren, R. E.

Publication type:

Article

Construction of a restriction-less, marker-less mutant useful for functional genomic and metabolic engineering of the biofuel producer Clostridium acetobutylicum.

Published in:

Biotechnology for Biofuels, 2016, v. 9, p. 1, doi. 10.1186/s13068-016-0432-2

By:

Croux, Christian;
Ngoc-Phuong-Thao Nguyen;
Jieun Lee;
Raynaud, Celine;
Saint-Prix, Florence;
Gonzalez-Pajuelo, Maria;
Meynial-Salles, Isabelle;
Soucaille, Philippe

Publication type:

Article

Emerging Gene Therapies for Retinal Degenerations.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 19, p. 6415, doi. 10.1523/JNEUROSCI.0295-12.2012

By:

Cepko, Constance L.

Publication type:

Article

Development of a markerless gene replacement system in Corynebacterium glutamicum using upp as a counter-selection marker.

Published in:

Biotechnology Letters, 2015, v. 37, n. 3, p. 609, doi. 10.1007/s10529-014-1718-8

By:

Ma, Wenwen;
Wang, Xiaoyue;
Mao, Yufeng;
Wang, Zhiwen;
Chen, Tao;
Zhao, Xueming

Publication type:

Article

Efficient homologous recombination with short length flanking fragments in Ku70 deficient Yarrowia lipolytica strains.

Published in:

Biotechnology Letters, 2013, v. 35, n. 4, p. 571, doi. 10.1007/s10529-012-1107-0

By:

Verbeke, Jonathan;
Beopoulos, Athanasios;
Nicaud, Jean-Marc

Publication type:

Article

A Novel Strategy for Cell-Autonomous Gene Knockdown in Caenorhabditis elegans Defines a Cell-Specific Function for the G-Protein Subunit GOA-1.

Published in:

Genetics, 2013, v. 194, n. 2, p. 363, doi. 10.1534/genetics.113.149724

By:

Maher, Kathryn N.;
Swaminathan, Aishwarya;
Patel, Parth;
Chase, Daniel L.

Publication type:

Article

Studying Recombination with High-Throughput Sequencing: An Educational Primer for Use with "Fine-Scale Heterogeneity in Crossover Rate in the garnet-scalloped Region of the Drosophila melanogaster X chromosome".

Published in:

Genetics, 2013, v. 194, n. 2, p. 335, doi. 10.1534/genetics.113.150771

By:

Heil, Caiti S. Smukowski;
Noor, Mohamed A. F.

Publication type:

Article

Critical review of non-statin treatments for dyslipoproteinemia.

Published in:

Expert Review of Cardiovascular Therapy, 2014, v. 12, n. 3, p. 359, doi. 10.1586/14779072.2014.888312

By:

Pang, Jing;
Chan, Dick C;
Watts, Gerald F

Publication type:

Article

Genome editing and transcriptional repression in <italic>Pseudomonas putida</italic> KT2440 via the type II CRISPR system.

Published in:

Microbial Cell Factories, 2018, v. 17, p. 1, doi. 10.1186/s12934-018-0887-x

By:

Sun, Jun;
Wang, Qingzhuo;
Jiang, Yu;
Wen, Zhiqiang;
Yang, Lirong;
Wu, Jianping;
Yang, Sheng

Publication type:

Article

Gene therapy in India: A focus.

Published in:

Journal of Biosciences, 2014, v. 39, n. 3, p. 537, doi. 10.1007/s12038-014-9431-2

By:

CHODISETTY, SARVANI;
REMINGTON NELSON, EVERETTE JACOB

Publication type:

Article

The Preference for Error-Free or Error-Prone Postreplication Repair in Saccharomyces cerevisiae Exposed to Low-Dose Methyl Methanesulfonate Is Cell Cycle Dependent.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 8, p. 1, doi. 10.1128/MCB.01392-12

By:

Dongqing Huang;
Piening, Brian D.;
Paulovich, Amanda G.

Publication type:

Article

Functional analysis of an essential Ran-binding protein gene, CpRbp1, from the chestnut blight fungus Cryphonectria parasitica using heterokaryon rescue.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65036-7

By:

Ko, Yo-Han;
Choi, So-Yeon;
So, Kum-Kang;
Kim, Jung-Mi;
Chun, Jeesun;
Kim, Dae-Hyuk

Publication type:

Article

Joining forces: first application of a rapamycin-induced dimerizable Cre system for conditional null mutant analysis in Leishmania.

Published in:

Molecular Microbiology, 2016, v. 100, n. 6, p. 923, doi. 10.1111/mmi.13374

By:

Späth, Gerald F.;
Clos, Joachim

Publication type:

Article

Conditional inactivation of A spergillus nidulans sarASAR1 uncovers the morphogenetic potential of regulating endoplasmic reticulum (ER) exit.

Published in:

Molecular Microbiology, 2015, v. 95, n. 3, p. 491, doi. 10.1111/mmi.12880

By:

Hernández‐González, Miguel;
Peñalva, Miguel A.;
Pantazopoulou, Areti

Publication type:

Article

Recent advances and future prospects in choroideremia.

Published in:

Clinical Ophthalmology, 2015, v. 9, p. 2195, doi. 10.2147/OPTH.S65732

By:

Zinkernagel, Martin S.;
MacLaren, Robert E.

Publication type:

Article

Muscle and Heart Function Restoration in a Limb Girdle Muscular Dystrophy 2I (LGMD2I) Mouse Model by Systemic FKRP Gene Delivery.

Published in:

Molecular Therapy, 2014, v. 22, n. 11, p. 1890, doi. 10.1038/mt.2014.141

By:

Qiao, Chunping;
Wang, Chi-Hsien;
Zhao, Chunxia;
Lu, Peijuan;
Awano, Hiroyuki;
Xiao, Bin;
Li, Jianbin;
Yuan, Zhenhua;
Dai, Yi;
Martin, Carrie Bette;
Li, Juan;
Lu, Qilong;
Xiao, Xiao

Publication type:

Article

Recombinant AAV as a Platform for Translating the Therapeutic Potential of RNA Interference.

Published in:

Molecular Therapy, 2014, v. 22, n. 4, p. 692, doi. 10.1038/mt.2013.285

By:

Borel, Florie;
Kay, Mark A;
Mueller, Christian

Publication type:

Article

Plasmapheresis Eliminates the Negative Impact of AAV Antibodies on Microdystrophin Gene Expression Following Vascular Delivery.

Published in:

Molecular Therapy, 2014, v. 22, n. 2, p. 338, doi. 10.1038/mt.2013.244

By:

Chicoine, LG;
Montgomery, CL;
Bremer, WG;
Shontz, KM;
Griffin, DA;
Heller, KN;
Lewis, S;
Malik, V;
Grose, WE;
Shilling, CJ;
Campbell, KJ;
Preston, TJ;
Coley, BD;
Martin, PT;
Walker, CM;
Clark, KR;
Sahenk, Z;
Mendell, JR;
Rodino-Klapac, LR

Publication type:

Article

A Comprehensive Review of Retinal Gene Therapy.

Published in:

Molecular Therapy, 2013, v. 21, n. 3, p. 509, doi. 10.1038/mt.2012.280

By:

Boye, Shannon E;
Boye, Sanford L;
Lewin, Alfred S;
Hauswirth, William W

Publication type:

Article

Nanoparticles for death-induced gene therapy in cancer (Review).

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1413, doi. 10.3892/mmr.2017.8091

By:

Roacho-Perez, Jorge A.;
Gallardo-Blanco, Hugo L.;
Sanchez-Dominguez, Margarita;
Garcia-Casillas, Perla E.;
Chapa-Gonzalez, Christian;
Sanchez-Dominguez, Celia N.

Publication type:

Article

Spliceosome-Mediated Trans-Splicing: The Therapeutic Cut and Paste.

Published in:

Journal of Investigative Dermatology, 2012, v. 132, n. 8, p. 1959, doi. 10.1038/jid.2012.101

By:

Wally, Verena;
Murauer, Eva M;
Bauer, Johann W

Publication type:

Article

Transcutaneous Gene Gun Delivery of hNC16A Induces BPAG2-Specific Tolerance.

Published in:

Journal of Investigative Dermatology, 2012, v. 132, n. 6, p. 1665, doi. 10.1038/jid.2012.19

By:

Ettinger, Monika;
Peckl-Schmid, Doris;
Gruber, Christina;
Laimer, Martin;
Thalhamer, Josef;
Hintner, Helmut;
Gratz, Iris K;
Bauer, Johann W

Publication type:

Article

A revolution coming to a classic model organism.

Published in:

Nature Methods, 2013, v. 10, n. 4, p. 303, doi. 10.1038/nmeth.2415

By:

Grunwald, David Jonah

Publication type:

Article

Efficient gene replacements in ku70 disruption strain of Aspergillus chevalieri var. intermedius.

Published in:

Biotechnology & Biotechnological Equipment, 2017, v. 31, n. 1, p. 16, doi. 10.1080/13102818.2016.1251828

By:

Huang, Qingqing;
Cao, Yang;
Liu, Zuoyi;
Tan, Yumei;
Liu, Yongxiang

Publication type:

Article

Proof-of-concept: neonatal intravenous injection of adeno-associated virus vectors results in successful transduction of myenteric and submucosal neurons in the mouse small and large intestine.

Published in:

Neurogastroenterology & Motility, 2016, v. 28, n. 2, p. 299, doi. 10.1111/nmo.12724

By:

Buckinx, R.;
Van Remoortel, S.;
Gijsbers, R.;
Waddington, S. N.;
Timmermans, J.‐P.

Publication type:

Article

Gene therapy for deafness: How close are we?

Published in:

Science Translational Medicine, 2015, v. 7, n. 295, p. 1, doi. 10.1126/scitranslmed.aac7545

By:

Moser, Tobias

Publication type:

Article

Gene Therapy for Sickle Cell Disease Shows Promise.

Published in:

JAMA: Journal of the American Medical Association, 2019, v. 321, n. 4, p. 334, doi. 10.1001/jama.2018.21119

By:

Rubin, Rita

Publication type:

Article

Promises and Pitfalls of Gene Therapy in Parkinson's Disease.

Published in:

2014

By:

Nichols, Emma Hitt

Publication type:

Proceeding

Infantile Pompe Disease and Enzyme Replacement Therapy.

Published in:

2017

By:

Amdani, Shahnawaz M;
Sanil, Yamuna

Publication type:

Case Study

PAS-LuxR transcriptional control of filipin biosynthesis in S. avermitilis.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 22, p. 9311, doi. 10.1007/s00253-014-5998-7

By:

Vicente, Cláudia;
Santos-Aberturas, Javier;
Payero, Tamara;
Barreales, Eva;
Pedro, Antonio;
Aparicio, Jesús

Publication type:

Article

A markerless gene replacement method for B. amyloliquefaciens LL3 and its use in genome reduction and improvement of poly-γ-glutamic acid production.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 21, p. 8963, doi. 10.1007/s00253-014-5824-2

By:

Zhang, Wei;
Gao, Weixia;
Feng, Jun;
Zhang, Chi;
He, Yulian;
Cao, Mingfeng;
Li, Qiang;
Sun, Yang;
Yang, Chao;
Song, Cunjiang;
Wang, Shufang

Publication type:

Article

ku70 and ku80 null mutants improve the gene targeting frequency in Monascus ruber M7.

Published in:

Applied Microbiology & Biotechnology, 2013, v. 97, n. 11, p. 4965, doi. 10.1007/s00253-013-4851-8

By:

He, Yi;
Liu, Qingpei;
Shao, Yanchun;
Chen, Fusheng

Publication type:

Article

Gene therapy - Principles and Applications.

Published in:

Global Journal of Transfusion Medicine, 2022, v. 7, n. 1, p. 3, doi. 10.4103/gjtm.gjtm_87_21

By:

Pathak, Sangeeta

Publication type:

Article

Myeloid development: Mice with a human innate compartment.

Published in:

Nature Reviews Immunology, 2014, v. 14, n. 4, p. 215, doi. 10.1038/nri3654

By:

Leavy, Olive

Publication type:

Article

Homoeologou GSL-ELONG gene replacement for manipulation of aliphatic glucosinolates in Brassica rapa L. by marker assisted selection.

Published in:

Frontiers in Plant Science, 2013, v. 4, p. 1, doi. 10.3389/fpls.2013.00055

By:

Hirani, Arvind H.;
Zelmer, Carla D.;
McVetty, Peter B. E.;
Genyi Li, Fouad Daayf;
Xun Xu;
Xiyin Wang

Publication type:

Article

Gene Replacement and Fluorescent Labeling to Study the Functional Role of Exopolysaccharides in Bifidobacterium animalis subsp. lactis.

Published in:

Frontiers in Microbiology, 2017, p. 1, doi. 10.3389/fmicb.2017.01405

By:

Castro-Bravo, Nuria;
Hidalgo-Cantabrana, Claudio;
Rodriguez-Carvajal, Miguel A.;
Ruas-Madiedo, Patricia;
Margolles, Abelardo

Publication type:

Article