Works matching DE "ANTIBODY-directed enzyme prodrug therapy"

Results: 96

Synthesis and characterization of a novel chitosan based E. coli cytosine deaminase nanocomposite for potential application in prodrug enzyme therapy.

Published in:

Biotechnology Letters, 2011, v. 33, n. 1, p. 153, doi. 10.1007/s10529-010-0416-4

By:

Yata, Vinod;
Ghosh, Siddhartha

Publication type:

Article

Plasma and cerebrospinal fluid pharmacokinetics of nelarabine in nonhuman primates.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 6, p. 743, doi. 10.1007/s00280-006-0328-0

By:

Berg, Stacey L.;
Brueckner, Claudia;
Nuchtern, Jed G.;
Dauser, Robert;
McGuffey, Leticia;
Blaney, Susan M.

Publication type:

Article

Cost Consequences of Adjuvant Capecitabine, Mayo Clinic and de Gramont Regimens for Stage III Colon Cancer in the French Setting.

Published in:

Oncology, 2007, v. 72, n. 3/4, p. 248, doi. 10.1159/000113016

By:

Douillard, J. Y.;
Tilleul, P.;
Ychou, M.;
Dufour, P.;
Perrocheau, G.;
Seitz, J. F.;
Maes, P.;
Lafuma, A.;
Husseini, F.

Publication type:

Article

Synthesis of 3'-Amino-3'-Deoxyguanosine and 3'-Amino-3'-Deoxyxyloguanosine Monophosphate Hepdirect Prodrugs from Guanosine.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2009, v. 28, n. 10, p. 969, doi. 10.1080/15257770903307151

By:

Bookser, BrettC.;
Raffaele, NicholasB.;
Reddy, K.Raja;
Fan, Kevin;
Huang, Wenjian;
Erion, MarkD.

Publication type:

Article

“Lock-in” Modified Cyclo Sal Nucleotides—The Second Generation of Cyclo Sal Prodrugs.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2005, v. 24, n. 5-7, p. 939, doi. 10.1081/NCN-200059298

By:

Vukadinović, D.;
Böge, N. P. H.;
Balzarini, J.;
Meier, C.

Publication type:

Article

Combination immunotherapy: Taking Cancer vaccines to the next Level.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00610

By:

Grenier, Jeremy M.;
Yeung, Stephen T.;
Khanna, Kamal M.

Publication type:

Article

Skin permeation of buprenorphine and its ester prodrugs from lipid nanoparticles: lipid emulsion, nanostructured lipid carriers and solid lipid nanoparticles.

Published in:

Journal of Microencapsulation, 2009, v. 26, n. 8, p. 734, doi. 10.3109/02652040902746679

By:

Wang, Jhi-Joung;
Liu, Kuo-Sheng;
Sung, K. C.;
Tsai, Chia-Yin;
Fang, Jia-You

Publication type:

Article

Impact of various treatment modalities on the outcome of stage IB1–IIA cervical adenocarcinoma

Published in:

2011

By:

Chen, Yu-Li;
Ho, Chih-Ming;
Chen, Chi-An;
Chiang, Ying-Cheng;
Huang, Chia-Yen;
Hsieh, Chang-Yao;
Cheng, Wen-Fang

Publication type:

journal article

PARP inhibitors and cancer therapy — early results and potentialapplications.

Published in:

British Journal of Radiology, 2008, v. 81, p. S2, doi. 10.1259/bjr/30872348

By:

Jones, C.;
Plummer, E. R.

Publication type:

Article

A triple suicide gene strategy that improves therapeutic effects and incorporates multimodality molecular imaging for monitoring gene functions.

Published in:

Cancer Gene Therapy, 2013, v. 20, n. 6, p. 358, doi. 10.1038/cgt.2013.28

By:

Xing, L.;
Sun, X.;
Deng, X.;
Kotedia, K.;
Zanzonico, P. B.;
Ackerstaff, E.;
Koutcher, J. A.;
Ling, C. C.;
Li, G. C.

Publication type:

Article

Tailoring the AIE Chromogen 2-(2-Hydroxyphenyl)benzothiazole for Use in Enzyme-Triggered Molecular Brachytherapy.

Published in:

Molecules, 2022, v. 27, n. 24, p. 8682, doi. 10.3390/molecules27248682

By:

Wu, Zhiyuan;
Dou, Jinghuai;
Nguyen, Kathy-Uyen;
Eppley, Jayden C.;
Siwawannapong, Kittipan;
Zhang, Yunlong;
Lindsey, Jonathan S.

Publication type:

Article

Anticancer Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144650

By:

Ammazzalorso, Alessandra;
Fantacuzzi, Marialuigia

Publication type:

Article

Coupling of a Novel TIMP3 Peptide to Carboxypeptidase G2 for Pro-Drug Activation at the Tumour Site.

Published in:

Molecules, 2021, v. 26, n. 3, p. 625, doi. 10.3390/molecules26030625

By:

Aldughaim, Mohammed S.;
Alsaffar, Fatimah;
Barker, Michael D.;
Kokotos, George;
Duarte, Iola F.

Publication type:

Article

Pro-Moieties of Antimicrobial Peptide Prodrugs.

Published in:

Molecules, 2015, v. 20, n. 1, p. 1210, doi. 10.3390/molecules20011210

By:

Forde, Eanna;
Devocelle, Marc

Publication type:

Article

Synthesis and Biological Evaluation of Novel 10-Substituted-7- ethyl-10-hydroxycamptothecin (SN-38) Prodrugs.

Published in:

Molecules, 2014, v. 19, n. 12, p. 19718, doi. 10.3390/molecules191219718

By:

Mo Zhou;
Meixia Liu;
Xinhua He;
Hong Yu;
Di Wu;
Yishan Yao;
Shiyong Fan;
Ping Zhang;
Weiguo Shi;
Bohua Zhong

Publication type:

Article

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer.

Published in:

Molecules, 2011, v. 16, n. 5, p. 4140, doi. 10.3390/molecules16054140

By:

Wachowska, Małgorzata;
Muchowicz, Angelika;
Firczuk, Małgorzata;
Gabrysiak, Magdalena;
Winiarska, Magdalena;
Wańczyk, Małgorzata;
Bojarczuk, Kamil;
Golab, Jakub

Publication type:

Article

1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs.

Published in:

Molecules, 2009, v. 14, n. 12, p. 5247, doi. 10.3390/molecules14125247

By:

Jai Moo Shin;
Sachs, George;
Young-moon Cho;
Garst, Michael

Publication type:

Article

A New Look at the Most Successful Prodrugs for Active Vitamin D (D Hormone): Alfacalcidol and Doxercalciferol.

Published in:

Molecules, 2009, v. 14, n. 10, p. 3869, doi. 10.3390/molecules14103869

By:

Kubodera, Noboru

Publication type:

Article

Carnitine Conjugate of Nipecotic Acid: A New Example of Dual Prodrug.

Published in:

Molecules, 2009, v. 14, n. 9, p. 3268, doi. 10.3390/molecules14093268

By:

Napolitano, Carmela;
Scaglianti, Martina;
Scalambra, Emanuela;
Manfredini, Stefano;
Ferraro, Luca;
Beggiato, Sarah;
Vertuani, Silvia

Publication type:

Article

Prasugrel.

Published in:

Formulary, 2008, v. 43, n. 11, p. 402

By:

Schilling, Jessica M.;
Kalus, James S.

Publication type:

Article

Icodextrin reduces adhesion formation following gynecological surgery in rabbits.

Published in:

Iranian Journal of Reproductive Medicine, 2011, v. 9, n. 3, p. 187

By:

Khani, Behnaz;
Bahrami, Nahid;
Mehrabian, Ferdous;
Naeni, Hormoz Naderi

Publication type:

Article

Chronic N-acetylcysteine after cocaine self-administration produces enduring reductions in drug-seeking.

Published in:

Neuropsychopharmacology, 2012, v. 37, n. 1, p. 298, doi. 10.1038/npp.2011.164

By:

Reichel, Carmela M;
See, Ronald E

Publication type:

Article

The development and psychometric analyses of ADEPT: an instrument for assessing the interactions between doctors and their elderly patients.

Published in:

2005

By:

Teresi, Jeanne A.;
Ramírez, Mildred;
Ocepek-Welikson, Katja;
Cook, Mary Ann;
Ramírez, Mildred

Publication type:

journal article

Azathioprine: a guide for the management of dermatology patients.

Published in:

Dermatologic Therapy, 2007, v. 20, n. 4, p. 206, doi. 10.1111/j.1529-8019.2007.00134.x

By:

Wise, Melissa;
Callen, Jeffrey P.

Publication type:

Article

Clinical Pharmacokinetics of XP13512, a Novel Transported Prodrug of Gabapentin.

Published in:

Journal of Clinical Pharmacology, 2008, v. 48, n. 12, p. 1378, doi. 10.1177/0091270008322909

By:

Cundy, Kenneth C.;
Sastry, Srikonda;
Wendy Luo;
Joan Zou;
Moors, Tristen L.;
Canafax, Daniel M.

Publication type:

Article

Chemotherapy through mitochondrial apoptosis using nutritional supplements and herbs: A brief overview.

Published in:

Journal of Bioenergetics & Biomembranes, 2007, v. 39, n. 1, p. 31, doi. 10.1007/s10863-006-9056-8

By:

Kang-Beom Kwon;
Byung-Hyun Park;
Do-Gon Ryu

Publication type:

Article

Polymeric Photosensitizer Prodrugs for Photodynamic Therapy.

Published in:

Photochemistry & Photobiology, 2007, v. 83, n. 4, p. 958, doi. 10.1111/j.1751-1097.2007.00090.x

By:

Campo, Marino A.;
Gabriel, Doris;
Kucera, Pavel;
Gurny, Robert;
Lange, Norbert

Publication type:

Article

Immunomodulatory Role of Chloroquine and Pyrimethamine in Plasmodium yoelii 17XL Infected Mice.

Published in:

Scandinavian Journal of Immunology, 2007, v. 65, n. 1, p. 54, doi. 10.1111/j.1365-3083.2006.01869.x

By:

Ramos-Avila, A.;
Ventura-Gallegos, J. L.;
Zentella-Dehesa, A.;
Machuca-Rodríguez, C.;
Moreno-Altamirano, M. M.;
Narváez, V.;
Legorreta-Herrera, M.

Publication type:

Article

Preparation and Evaluation of Directly Compressible Forms of Mutual Prodrugs of Ibuprofen.

Published in:

Indian Journal of Pharmaceutical Sciences, 2006, v. 68, n. 4, p. 425

By:

Bhosale, A. V.;
Agrawal, G. P.;
Mishra, P.

Publication type:

Article

Mutual Prodrug Concept: Fundamentals and Applications.

Published in:

Indian Journal of Pharmaceutical Sciences, 2006, v. 68, n. 3, p. 286

By:

Bhosle, D.;
Bharambe, S.;
Gairola, Neha;
Dhaneshwar, Suneela S.

Publication type:

Article

Antibody-Directed Enzyme Prodrug Therapy: A Promising Approach for a Selective Treatment of Cancer Based on Prodrugs and Monoclonal Antibodies.

Published in:

Chemical Biology & Drug Design, 2009, v. 74, n. 3, p. 205, doi. 10.1111/j.1747-0285.2009.00856.x

By:

Tietze, Lutz F.;
Krewer, Birgit

Publication type:

Article

Membrane-localized activation of glucuronide prodrugs by β-glucuronidase enzymes.

Published in:

Cancer Gene Therapy, 2007, v. 14, n. 2, p. 187, doi. 10.1038/sj.cgt.7700999

By:

Chen, K-C.;
Cheng, T-L.;
Leu, Y-L.;
Prijovich, Z. M.;
Chuang, C-H.;
Chen, B-M.;
Roffler, S. R.

Publication type:

Article

Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology.

Published in:

Analytical & Bioanalytical Chemistry, 2011, v. 401, n. 5, p. 1681, doi. 10.1007/s00216-011-5244-4

By:

Saccomanni, G.;
Giorgi, M.;
Carlo, S.;
Manera, C.;
Saba, A.;
Macchia, M.

Publication type:

Article

Novel approaches on prodrug based drug design.

Published in:

Pharmaceutical Chemistry Journal, 2008, v. 42, n. 12, p. 677, doi. 10.1007/s11094-009-0213-3

By:

Rasheed, A.;
Kumar, C.

Publication type:

Article

Nitric Oxide Donor Activity of Antihypertensive Drugs Guanoxan, Guanabenz, and Moxonidine.

Published in:

Pharmaceutical Chemistry Journal, 2004, v. 38, n. 2, p. 78, doi. 10.1023/B:PHAC.0000032483.57246.3b

By:

Danilov, A. V.;
Azimov, V. A.;
Levina, V. I.;
Pyatakova, N. V.;
Severina, I. S.;
Grigor'ev, N. B.;
Granik, V. G.

Publication type:

Article

Unmasking the immune recognition of prostate cancer with CTLA4 blockade.

Published in:

2012

By:

Kwek, Serena S.;
Cha, Edward;
Fong, Lawrence

Publication type:

Opinion

Synthesis of Piperazinylalkyl Ester Prodrugs of Ketorolac and their In Vitro Evaluation for Transdermal Delivery.

Published in:

Drug Development & Industrial Pharmacy, 2008, v. 34, n. 10, p. 1054, doi. 10.1080/03639040801946681

By:

Qandil, Amjad;
Al-Nabulsi, Soraya;
Al-Taani, Bashar;
Tashtoush, Bassam

Publication type:

Article

Design of an IV Formulation of an Unstable Prodrug Candidate for Prostate Cancer Treatment: Solution Chemistry of N-(glutaryl-hyp-ala-ser-cyclohexylglycyl-gln-ser-leu)-doxorubicin.

Published in:

Drug Development & Industrial Pharmacy, 2006, v. 32, n. 3, p. 327, doi. 10.1080/03639040500518997

By:

Karki, Shyam B.;
Treemaneekarn, Varaporn;
Ostovic, Drazen;
Nerurkar, Maneesh;
Almarsson, Örn

Publication type:

Article

Synthesis of adamantyl-containing cidofovir analogs as potential antiviral prodrugs with high bioavailability parameters.

Published in:

Russian Journal of General Chemistry, 2015, v. 85, n. 2, p. 402, doi. 10.1134/S1070363215020097

By:

Reznikov, A.;
Skomorokhov, M.;
Leonova, M.;
Klimochkin, Yu.

Publication type:

Article

Dual-targeting for brain-specific drug delivery: synthesis and biological evaluation.

Published in:

Drug Delivery, 2018, v. 25, n. 1, p. 426, doi. 10.1080/10717544.2018.1431978

By:

Yue, Qiming;
Peng, Yao;
Zhao, Yi;
Lu, Runxin;
Fu, Qiuyi;
Chen, Yang;
Yang, Yang;
Hai, Li;
Guo, Li;
Wu, Yong

Publication type:

Article

Ciclesonide in the Management of Asthma.

Published in:

Clinical Medicine: Therapeutics, 2009, n. 1, p. 1437, doi. 10.4137/CMT.S2133

By:

Gonzalez, Daniel;
Derendorf, Hartmut

Publication type:

Article

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME 3,5-DISUBSTITUTED-TETRAHYDRO-2H-1,3,5-THIADIAZINE- 2-THIONE DERIVATIVES.

Published in:

Turkish Journal of Pharmaceutical Sciences, 2011, v. 8, n. 2, p. 159

By:

Sağlam, Evren;
Saraç, Selma;
Kiliç, Ekrem;
Özalp, Meral;
Ertan, Mevlüt

Publication type:

Article

Sublingual immunotherapy: adherence based on timing and monitoring control visits.

Published in:

2010

By:

Vita, D.;
Caminiti, L.;
Ruggeri, P.;
Pajno, G. B.

Publication type:

Other

Oral Communications - Treatment and Diagnosis of Venom Allergy.

Published in:: 1998
Publication type:: Abstract

Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrug.

Published in:

BMC Chemical Biology, 2001, v. 1, p. 4, doi. 10.1186/1472-6769-1-4

By:

Yuqiang Wang;
Huiling Yuan;
Wright, Susan C.;
Hong Wang;
Larrick, James W.

Publication type:

Article

Wohldefinierte polymere Paclitaxel-Prodrugs über eine Grafting-From-Methode ausgehend vom Arzneistoff.

Published in:

Angewandte Chemie, 2016, v. 128, n. 39, p. 11967, doi. 10.1002/ange.201605892

By:

Louage, Benoit;
Nuhn, Lutz;
Risseeuw, Martijn D. P.;
Vanparijs, Nane;
De Coen, Ruben;
Karalic, Izet;
Van Calenbergh, Serge;
De Geest, Bruno G.

Publication type:

Article

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.

Published in:

Nature, 2014, v. 511, n. 7507, p. 99, doi. 10.1038/nature13489

By:

Mayer-Barber, Katrin D.;
Andrade, Bruno B.;
Oland, Sandra D.;
Amaral, Eduardo P.;
Barber, Daniel L.;
Gonzales, Jacqueline;
Derrick, Steven C.;
Shi, Ruiru;
Kumar, Nathella Pavan;
Wei, Wang;
Yuan, Xing;
Zhang, Guolong;
Cai, Ying;
Babu, Subash;
Catalfamo, Marta;
Salazar, Andres M.;
Via, Laura E.;
Barry III, Clifton E.;
Sher, Alan

Publication type:

Article

Trial watch: Immunotherapy shows promise in Phase III neuroblastoma trial.

Published in:: Nature Reviews Drug Discovery, 2009, v. 8, n. 8, p. 604, doi. 10.1038/nrd2951
Publication type:: Article

Prodrugs: design and clinical applications.

Published in:

Nature Reviews Drug Discovery, 2008, v. 7, n. 3, p. 255, doi. 10.1038/nrd2468

By:

Rautio, Jarkko;
Kumpulainen, Hanna;
Heimbach, Tycho;
Oliyai, Reza;
Oh, Dooman;
Järvinen, Tomi;
Savolainen, Jouko

Publication type:

Article

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY EVALUATION OF NEW SULFAMETHOXAZOLE-PHOSPHATE ESTER PRODRUGS AND THEIR RELEASE AT DIFFERENT ACIDIC MEDIA.

Published in:

Biochemical & Cellular Archives, 2021, v. 21, n. 1, p. 433

By:

Eraibi, Fatima Abdulkareem;
Hameed, Ayad Saadi

Publication type:

Article