Works matching DE "NUCLEASE genetics"
Results: 70
The Rad1-Rad10 nuclease promotes chromosome translocations between dispersed repeats.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 964, doi. 10.1038/nsmb.2359
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- Article
The molecular architecture of human Dicer.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 436, doi. 10.1038/nsmb.2268
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- Article
CRISPR-Cas immunity in prokaryotes.
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- Nature, 2015, v. 526, n. 7571, p. 55, doi. 10.1038/nature15386
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- Article
Biotechnology: Programming genomes with light.
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- Nature, 2013, v. 500, n. 7463, p. 406, doi. 10.1038/500406a
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- Article
Genome editing in plants via designed zinc finger nucleases.
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- In Vitro Cellular & Developmental Biology Plant, 2015, v. 51, n. 1, p. 1, doi. 10.1007/s11627-015-9663-3
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- Article
DNA2--An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?
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- International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1562, doi. 10.3390/ijms18071562
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- Article
Homologous Recombination-Independent Large Gene Cassette Knock-in in CHO Cells Using TALEN and MMEJ-Directed Donor Plasmids.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 10, p. 23849, doi. 10.3390/ijms161023849
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- Article
Role of endonuclease G in exogenous DNA stability in HeLa cells.
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- Biochemistry (00062979), 2016, v. 81, n. 2, p. 163, doi. 10.1134/S0006297916020103
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- Article
Application of ZFN for Site Directed Mutagenesis of Rice <italic>SSIVa</italic> Gene.
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- Biotechnology & Bioprocess Engineering, 2018, v. 23, n. 1, p. 108, doi. 10.1007/s12257-017-0420-9
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- Article
Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling.
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- Molecular Biology Reports, 2013, v. 40, n. 7, p. 4251, doi. 10.1007/s11033-013-2507-5
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- Article
A history of genome editing in mammals.
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- Mammalian Genome, 2017, v. 28, n. 7/8, p. 237, doi. 10.1007/s00335-017-9699-2
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- Article
A triple-helix forming oligonucleotide targeting genomic DNA fails to induce mutation.
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- Mutagenesis, 2012, v. 27, n. 6, p. 713, doi. 10.1093/mutage/ges037
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- Article
CRISPR/Cas9 und andere Genome Editing Techniken.
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- 2017
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- Abstract
Enhancing Targeted Genomic DNA Editing in Chicken Cells Using the CRISPR/Cas9 System.
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- PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0169768
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- Article
The Mechanism of Gene Targeting in Human Somatic Cells.
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- PLoS Genetics, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.pgen.1004251
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- Article
Coincident Resection at Both Ends of Random, γ- Induced Double-Strand Breaks Requires MRX (MRN), Sae2 (Ctp1), and Mre11-Nuclease.
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- PLoS Genetics, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.pgen.1003420
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- Article
Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome.
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- PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002861
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- Article
Targeted Modification of Gene Function Exploiting Homology-Directed Repair of TALEN-Mediated Double-Strand Breaks in Barley.
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- G3: Genes | Genomes | Genetics, 2015, v. 5, n. 9, p. 1857, doi. 10.1534/g3.115.018762
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- Article
Plant genome editing with TALEN and CRISPR.
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- Cell & Bioscience, 2017, v. 7, p. 1, doi. 10.1186/s13578-017-0148-4
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- Article
Genome editing in potato plants by agrobacterium-mediated transient expression of transcription activator-like effector nucleases.
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- Plant Biotechnology Reports, 2017, v. 11, n. 5, p. 249, doi. 10.1007/s11816-017-0448-5
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- Article
Genome editing for targeted improvement of plants.
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- Plant Biotechnology Reports, 2016, v. 10, n. 6, p. 327, doi. 10.1007/s11816-016-0417-4
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- Article
Genomic editing opens new avenues for zebrafish as a model for neurodegeneration.
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- Journal of Neurochemistry, 2013, v. 127, n. 4, p. 461, doi. 10.1111/jnc.12460
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- Article
E-CRISP: fast CRISPR target site identification.
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- Nature Methods, 2014, v. 11, n. 2, p. 122, doi. 10.1038/nmeth.2812
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- Article
Model organisms: Conditional gene knockouts in worms.
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- Nature Methods, 2013, v. 10, n. 10, p. 933, doi. 10.1038/nmeth.2668
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- Article
A revolution coming to a classic model organism.
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- Nature Methods, 2013, v. 10, n. 4, p. 303, doi. 10.1038/nmeth.2415
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- Article
Robust, synergistic regulation of human gene expression using TALE activators.
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- Nature Methods, 2013, v. 10, n. 3, p. 243, doi. 10.1038/nmeth.2366
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- Article
Improving gene-editing nucleases.
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- Nature Methods, 2012, v. 9, n. 6, p. 536, doi. 10.1038/nmeth.2060
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- Article
An optimized two-finger archive for ZFN-mediated gene targeting.
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- Nature Methods, 2012, v. 9, n. 6, p. 588, doi. 10.1038/nmeth.1994
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- Article
Rapid, precise quantification of large DNA excisions and inversions by ddPCR.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71742-z
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- Article
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13007-6
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- Article
Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-12922-y
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- Article
Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin.
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- Nucleus (1949-1034), 2015, v. 6, n. 1, p. 30, doi. 10.4161/19491034.2014.990855
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- Article
Genome Editing: A New Horizon for Oral and Craniofacial Research.
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- 2019
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- journal article
Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases.
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- Human Genetics, 2016, v. 135, n. 9, p. 1093, doi. 10.1007/s00439-016-1710-6
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- Article
Multiple copies of a linear donor fragment released in situ from a vector improve the efficiency of zinc-finger nuclease-mediated genome editing.
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- Gene Therapy, 2014, v. 21, n. 3, p. 282, doi. 10.1038/gt.2013.83
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- Article
Gene transfer of integration defective anti-HSV-1 meganuclease to human corneas ex vivo.
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- Gene Therapy, 2014, v. 21, n. 3, p. 272, doi. 10.1038/gt.2013.82
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- Article
Cytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN).
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- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0122059
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- Article
Evaluation of sgRNA Target Sites for CRISPR-Mediated Repression of TP53.
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- PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113232
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- Article
Bacterial Delivery of TALEN Proteins for Human Genome Editing.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091547
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- Article
A Modified TALEN-Based Strategy for Rapidly and Efficiently Generating Knockout Mice for Kidney Development Studies.
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- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084893
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- Article
Rapid Assembly of Customized TALENs into Multiple Delivery Systems.
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- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080281
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- Publication type:
- Article
The Design and <i>In Vivo</i> Evaluation of Engineered I-OnuI-Based Enzymes for HEG Gene Drive.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074254
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- Article
Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs).
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- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037877
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- Publication type:
- Article
Targeted genome modification of crop plants using a CRISPR-Cas system.
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- Nature Biotechnology, 2013, v. 31, n. 8, p. 686, doi. 10.1038/nbt.2650
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- Article
Knockout mice created by TALEN-mediated gene targeting.
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- Nature Biotechnology, 2013, v. 31, n. 1, p. 23, doi. 10.1038/nbt.2477
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- Publication type:
- Article
Functional Interplay between the 53BP1-Ortholog Rad9 and the Mre11 Complex Regulates Resection, End-Tethering and Repair of a Double-Strand Break.
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- PLoS Genetics, 2015, v. 11, n. 1, p. 1, doi. 10.1371/journal.pgen.1004928
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- Article
Improving Fab' fragment retention in an autonucleolytic Escherichia coli strain by swapping periplasmic nuclease translocation signal from OmpA to DsbA.
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- Biotechnology Letters, 2017, v. 39, n. 12, p. 1865, doi. 10.1007/s10529-017-2425-z
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- Article
Zinc Finger Nuclease–Mediated Knockout of AHR or ARNT in Human Breast Cancer Cells Abolishes Basal and Ligand-Dependent Regulation of CYP1B1 and Differentially Affects Estrogen Receptor α Transactivation.
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- Toxicological Sciences, 2014, v. 138, n. 1, p. 89, doi. 10.1093/toxsci/kft274
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- Article
In This Issue.
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- Molecular Therapy, 2015, v. 23, n. 10, p. 1554, doi. 10.1038/mt.2015.159
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- Article
Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.
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- Molecular Therapy, 2015, v. 23, n. 8, p. 1380, doi. 10.1038/mt.2015.71
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- Article