Works matching DE "ALLOSTERIC proteins"

Results: 387

Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 56, doi. 10.1038/nsmb.2705

By:

Alexander, Nathan S;
Preininger, Anita M;
Kaya, Ali I;
Stein, Richard A;
Hamm, Heidi E;
Meiler, Jens

Publication type:

Article

Allosteric control of the ribosome by small-molecule antibiotics.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 957, doi. 10.1038/nsmb.2360

By:

Wang, Leyi;
Pulk, Arto;
Wasserman, Michael R;
Feldman, Michael B;
Altman, Roger B;
Doudna Cate, Jamie H;
Blanchard, Scott C

Publication type:

Article

Enhanced interrogation: emerging strategies for cell signaling inhibition.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 646, doi. 10.1038/nsmb0610-646

By:

Huang, Rong;
Martinez-Ferrando, Isabel;
Cole, Philip A.

Publication type:

Article

Membrane-dependent signal integration by the Ras activator Son of sevenless.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 452, doi. 10.1038/nsmb.1418

By:

Gureasko, Jodi;
Galush, William J.;
Boykevisch, Sean;
Sondermann, Holger;
Bar-Sagi, Dafna;
Groves, Jay T.;
Kuriyan, John

Publication type:

Article

Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 5, p. 432, doi. 10.1038/nsmb1236

By:

Reissmann, Stefanie;
Parnot, Charles;
Booth, Christopher R;
Wah Chiu;
Frydman, Judith

Publication type:

Article

Conformational restriction blocks glutamate receptor desensitization.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 12, p. 1120, doi. 10.1038/nsmb1178

By:

Weston, Matthew C.;
Schuck, Peter;
Ghosal, Alokesh;
Rosenmund, Christian;
Mayer, Mark L.

Publication type:

Article

Recent advances in the development of allosteric protein tyrosine phosphatase inhibitors for drug discovery.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 3, p. 1064, doi. 10.1002/med.21871

By:

Elhassan, Reham M.;
Hou, Xuben;
Fang, Hao

Publication type:

Article

Structure-based prediction of protein-protein binding affinity with consideration of allosteric effect.

Published in:

Amino Acids, 2012, v. 43, n. 2, p. 531, doi. 10.1007/s00726-011-1101-1

By:

Tian, Feifei;
Lv, Yonggang;
Yang, Li

Publication type:

Article

Use of Allosteric Targets in the Discovery of Safer Drugs.

Published in:

Medical Principles & Practice, 2013, v. 22, n. 5, p. 418, doi. 10.1159/000350417

By:

Grover, Ashok Kumar

Publication type:

Article

Protein kinase C showcases allosteric control: activation of LRRK1.

Published in:

Biochemical Journal, 2023, v. 480, n. 3, p. 219, doi. 10.1042/BCJ20220507

By:

Tovell, Hannah;
Newton, Alexandra C.

Publication type:

Article

AlloSigMA: allosteric signaling and mutation analysis server.

Published in:

Bioinformatics, 2017, v. 33, n. 24, p. 3996, doi. 10.1093/bioinformatics/btx430

By:

Guarnera, Enrico;
Zhen Wah Tan;
Zejun Zheng;
Berezovsky, Igor N.

Publication type:

Article

Statistical database analysis of the role of loop dynamics for protein-protein complex formation and allostery.

Published in:

Bioinformatics, 2017, v. 33, n. 12, p. 1814, doi. 10.1093/bioinformatics/btx070

By:

Yina Gu;
Da-Wei Li;
Brüschweiler, Rafael

Publication type:

Article

Using kernelized partial canonical correlation analysis to study directly coupled side chains and allostery in small G proteins.

Published in:: Bioinformatics, 2015, v. 31, n. 12, p. i124, doi. 10.1093/bioinformatics/btv241
Publication type:: Article

ChIPmix: mixture model of regressions for two-color ChIP-chip analysis.

Published in:

Bioinformatics, 2008, v. 24, n. 16, p. i181, doi. 10.1093/bioinformatics/btn280

By:

Marie-Laure Martin-Magniette;
Tristan Mary-Huard;
Caroline Bérard;
Stéphane Robin

Publication type:

Article

Natively unstructured regions in proteins identified from contact predictions.

Published in:

Bioinformatics, 2007, v. 23, n. 18, p. 2376, doi. 10.1093/bioinformatics/btm349

By:

Avner Schlessinger;
Marco Punta;
Burkhard Rost

Publication type:

Article

Formyl Peptide Receptors in Mice and Men: Similarities and Differences in Recognition of Conventional Ligands and Modulating Lipopeptides.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 2, p. 191, doi. 10.1111/bcpt.12903

By:

Winther, Malene;
Dahlgren, Claes;
Forsman, Huamei

Publication type:

Article

Conformational Dynamics of Mitochondrial Inorganic Pyrophosphatase hPPA2 and Its Changes Caused by Pathogenic Mutations.

Published in:

Life (2075-1729), 2025, v. 15, n. 1, p. 100, doi. 10.3390/life15010100

By:

Bezpalaya, Ekaterina;
Kurilova, Svetlana;
Vorobyeva, Nataliya;
Rodina, Elena

Publication type:

Article

The EAG Voltage-Dependent K<sup>+</sup> Channel Subfamily: Similarities and Differences in Structural Organization and Gating.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00411

By:

Barros, Francisco;
de la Peña, Pilar;
Domínguez, Pedro;
Sierra, Luisa Maria;
Pardo, Luis A.

Publication type:

Article

Identification of basepairs within Tn5 termini that are critical sfor H-NS binding to the transpososome and regulation of Tn5 transposition.

Published in:: Mobile DNA, 2012, v. 3, n. 1, p. 7, doi. 10.1186/1759-8753-3-7
Publication type:: Article

Molecular Dynamic Simulation Reveals Structure Differences in APOL1 Variants and Implication in Pathogenesis of Chronic Kidney Disease.

Published in:

Genes, 2022, v. 13, n. 8, p. 1460, doi. 10.3390/genes13081460

By:

Mayanja, Richard;
Kintu, Christopher;
Diabate, Oudou;
Soremekun, Opeyemi;
Oluwagbemi, Olugbenga Oluseun;
Wele, Mamadou;
Kalyesubula, Robert;
Jjingo, Daudi;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.

Published in:

Molecular Brain, 2017, v. 10, p. 1, doi. 10.1186/s13041-017-0293-z

By:

Maksymetz, James;
Moran, Sean P.;
Conn, P. Jeffrey

Publication type:

Article

Allosteric binding sites in Rab11 for potential drug candidates.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0198632

By:

Kumar, Ammu Prasanna;
Lukman, Suryani

Publication type:

Article

Dissimilar flexibility of α and β subunits of human adult hemoglobin influences the protein dynamics and its alteration induced by allosteric effectors.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194994

By:

Schay, Gusztáv;
Kaposi, András D.;
Smeller, László;
Szigeti, Krisztián;
Fidy, Judit;
Herenyi, Levente

Publication type:

Article

On the possible role of protein vibrations in information processing in the brain: three Russian dolls.

Published in:

Frontiers in Molecular Neuroscience, 2015, v. 8, p. 1, doi. 10.3389/fnmol.2015.00038

By:

Smythies, John

Publication type:

Article

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.

Published in:

Nature Medicine, 2010, v. 16, n. 2, p. 205, doi. 10.1038/nm.2091

By:

Janes, Matthew R.;
Limon, Jose J.;
So, Lomon;
Jing Chen;
Lim, Raymond J.;
Chavez, Melissa A.;
Vu, Collin;
Lilly, Michael B.;
Mallya, Sharmila;
Ong, S. Tiong;
Konopleva, Marina;
Martin, Michael B.;
Ren, Pingda;
Yi Liu;
Rommel, Christian;
Fruman, David A.

Publication type:

Article

CONCERTED MOTIONS IN ALLOSTERIC MODEL PROTEINS AT TERAHERTZ FREQUENCIES.

Published in:

AAPP Physical, Mathematical & Natural Sciences / Atti della Accademia Peloritana dei Pericolanti: Classe di Scienze Fisiche, Matematiche e Naturali, 2018, v. 96, n. 1, p. 1, doi. 10.1478/AAPP.961A6

By:

NIBALI, VALERIA CONTI;
MORRA, GIULIA;
HAVENITH, MARTINA;
D'ANGELO, GIOVANNA;
COLOMBO, GIORGIO

Publication type:

Article

Allosteric Effect of Adenosine Triphosphate on Peptide Recognition by 3′5′-Cyclic Adenosine Monophosphate Dependent Protein Kinase Catalytic Subunits.

Published in:

Protein Journal, 2016, v. 35, n. 6, p. 459, doi. 10.1007/s10930-016-9691-9

By:

Kivi, Rait;
Solovjova, Karina;
Haljasorg, Tõiv;
Arukuusk, Piret;
Järv, Jaak

Publication type:

Article

Thermodynamic Aspects of cAMP Dependent Protein Kinase Catalytic Subunit Allostery.

Published in:

Protein Journal, 2014, v. 33, n. 4, p. 386, doi. 10.1007/s10930-014-9570-1

By:

Kivi, Rait;
Jemth, Per;
Järv, Jaak

Publication type:

Article

Epistatic interactions modulate the evolution of mammalianmitochondrial respiratory complex components.

Published in:

BMC Genomics, 2009, v. 10, p. 266, doi. 10.1186/1471-2164-10-266

By:

Azevedo, Luísa;
Carneiro, João;
van Asch, Barbara;
Moleirinho, Ana;
Pereira, Filipe;
Amorim, António

Publication type:

Article

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.

Published in:

PLoS Pathogens, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.ppat.1005194

By:

Arnold, Laurence H.;
Groom, Harriet C. T.;
Kunzelmann, Simone;
Schwefel, David;
Caswell, Sarah J.;
Ordonez, Paula;
Mann, Melanie C.;
Rueschenbaum, Sabrina;
Goldstone, David C.;
Pennell, Simon;
Howell, Steven A.;
Stoye, Jonathan P.;
Webb, Michelle;
Taylor, Ian A.;
Bishop, Kate N.

Publication type:

Article

Cover Feature: Computational Design and Study of Artificial Selenoenzyme with Controllable Activity Based on an Allosteric Protein Scaffold (Chem. Eur. J. 44/2019).

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 44, p. 10249, doi. 10.1002/chem.201902345

By:

Li, Siyuan;
Xu, Wanjia;
Chu, Shengnan;
Ma, Ningning;
Liu, Shengda;
Li, Xiumei;
Wang, Tingting;
Jiang, Xiaojia;
Li, Fei;
Li, Yijia;
Zhang, Dongmei;
Luo, Quan;
Liu, Junqiu

Publication type:

Article

Computational Design and Study of Artificial Selenoenzyme with Controllable Activity Based on an Allosteric Protein Scaffold.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 44, p. 10350, doi. 10.1002/chem.201901480

By:

Li, Siyuan;
Xu, Wanjia;
Chu, Shengnan;
Ma, Ningning;
Liu, Shengda;
Li, Xiumei;
Wang, Tingting;
Jiang, Xiaojia;
Li, Fei;
Li, Yijia;
Zhang, Dongmei;
Luo, Quan;
Liu, Junqiu

Publication type:

Article

Frontispiece: Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 22, p. n/a, doi. 10.1002/chem.201782262

By:

D'Annessa, Ilda;
Sattin, Sara;
Tao, Jiahui;
Pennati, Marzia;
Sànchez ‐ Martìn, Carlos;
Moroni, Elisabetta;
Rasola, Andrea;
Zaffaroni, Nadia;
Agard, David A.;
Bernardi, Anna;
Colombo, Giorgio

Publication type:

Article

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 22, p. 5188, doi. 10.1002/chem.201700169

By:

D'Annessa, Ilda;
Sattin, Sara;
Tao, Jiahui;
Pennati, Marzia;
Sànchez ‐ Martìn, Carlos;
Moroni, Elisabetta;
Rasola, Andrea;
Zaffaroni, Nadia;
Agard, David A.;
Bernardi, Anna;
Colombo, Giorgio

Publication type:

Article

Alpha-fetoprotein contributes to THP-1 cell invasion and chemotaxis via protein kinase and Gi-protein-dependent pathways.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 379, n. 1/2, p. 283, doi. 10.1007/s11010-013-1650-6

By:

Zubkova, Ekaterina;
Semenkova, Lidiya;
Dudich, Elena;
Dudich, Igor;
Parfyonova, Yelena;
Menshikov, Mikhail

Publication type:

Article

Gating Models of the Anomalous Mole-Fraction Effect of Single-Channel Current in Chara.

Published in:

Journal of Membrane Biology, 2003, v. 192, n. 1, p. 45, doi. 10.1007/s00232-002-1063-z

By:

Hansen, U. P.;
Cakan, O.;
Abshagen-Keunecke, M.;
Farokhi, A.

Publication type:

Article

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.

Published in:

Nature, 2015, v. 527, n. 7579, p. 477, doi. 10.1038/nature15699

By:

Huang, Xi-Ping;
Karpiak, Joel;
Kroeze, Wesley K.;
Zhu, Hu;
Chen, Xin;
Moy, Sheryl S.;
Saddoris, Kara A.;
Nikolova, Viktoriya D.;
Farrell, Martilias S.;
Wang, Sheng;
Mangano, Thomas J.;
Deshpande, Deepak A.;
Jiang, Alice;
Penn, Raymond B.;
Jin, Jian;
Koller, Beverly H.;
Kenakin, Terry;
Shoichet, Brian K.;
Roth, Bryan L.

Publication type:

Article

Universal allosteric mechanism for Gα activation by GPCRs.

Published in:

Nature, 2015, v. 524, n. 7564, p. 173, doi. 10.1038/nature14663

By:

Flock, Tilman;
Ravarani, Charles N. J.;
Sun, Dawei;
Venkatakrishnan, A. J.;
Kayikci, Melis;
Tate, Christopher G.;
Veprintsev, Dmitry B.;
Babu, M. Madan

Publication type:

Article

A New Look at the Structures of Old Sepsis Actors by Exploratory Data Analysis Tools.

Published in:

Antibiotics (2079-6382), 2019, v. 8, n. 4, p. 225, doi. 10.3390/antibiotics8040225

By:

Gnoni, Antonio;
De Nitto, Emanuele;
Scacco, Salvatore;
Santacroce, Luigi;
Palese, Luigi Leonardo

Publication type:

Article

Room‐temperature serial synchrotron crystallography of the human phosphatase PTP1B.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2023, v. 79, n. 1, p. 23, doi. 10.1107/S2053230X22011645

By:

Sharma, Shivani;
Ebrahim, Ali;
Keedy, Daniel A.

Publication type:

Article

Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.66181

By:

Subramanian, Subu;
Gorday, Kent;
Marcus, Kendra;
Orellana, Matthew R.;
Ren, Peter;
Xiao Ran Luo;
O'Donnell, Michael E.;
Kuriyan, John

Publication type:

Article

Understanding biomolecular motion, recognition, and allostery by use of conformational ensembles.

Published in:

European Biophysics Journal, 2011, v. 40, n. 12, p. 1339, doi. 10.1007/s00249-011-0754-8

By:

Fenwick, R.;
Esteban-Martín, Santi;
Salvatella, Xavier

Publication type:

Article

Pregabalin: as adjunctive treatment of partial seizures.

Published in:

2005

By:

Warner, Greg;
Figgitt, David P.

Publication type:

journal article

Increase of the Corticosterone Level in Ducklings During the Sensitive Period of the Following Response.

Published in:

Developmental Psychobiology, 1977, v. 10, n. 1, p. 59, doi. 10.1002/dev.420100109

By:

Weiss, J.;
Köhler, W.;
Landsberg, J.-W.

Publication type:

Article

Neural relational inference to learn long-range allosteric interactions in proteins from molecular dynamics simulations.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29331-3

By:

Zhu, Jingxuan;
Wang, Juexin;
Han, Weiwei;
Xu, Dong

Publication type:

Article

Engineering and exploiting synthetic allostery of NanoLuc luciferase.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28425-2

By:

Guo, Zhong;
Parakra, Rinky D.;
Xiong, Ying;
Johnston, Wayne A.;
Walden, Patricia;
Edwardraja, Selvakumar;
Moradi, Shayli Varasteh;
Ungerer, Jacobus P. J.;
Ai, Hui-wang;
Phillips, Jonathan J.;
Alexandrov, Kirill

Publication type:

Article

Two-colour single-molecule photoinduced electron transfer fluorescence imaging microscopy of chaperone dynamics.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27286-5

By:

Schubert, Jonathan;
Schulze, Andrea;
Prodromou, Chrisostomos;
Neuweiler, Hannes

Publication type:

Article

Epistasis shapes the fitness landscape of an allosteric specificity switch.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25826-7

By:

Nishikawa, Kyle K.;
Hoppe, Nicholas;
Smith, Robert;
Bingman, Craig;
Raman, Srivatsan

Publication type:

Article

Molecular phylogenetic analyses of albuminoids reveal the molecular evolution of allosteric properties.

Published in:

IUBMB Life, 2013, v. 65, n. 6, p. 544, doi. 10.1002/iub.1164

By:

Ascenzi, Paolo;
di Masi, Alessandra;
Leboffe, Loris;
Alberio, Tiziana;
Fanali, Gabriella;
Fasano, Mauro

Publication type:

Article

Histidine146 of human serum albumin plays a prominent role at the interface of subdomains IA and IIA in allosteric ligand binding.

Published in:

IUBMB Life, 2011, v. 63, n. 4, p. 277, doi. 10.1002/iub.457

By:

Kaneko, Kenichi;
Chuang, Victor Tuan Giam;
Minomo, Ai;
Yamasaki, Keishi;
Bhagavan, Nadhipuram V.;
Maruyama, Toru;
Otagiri, Masaki

Publication type:

Article