Parental Factors Associated with Child or Adolescent Medication Adherence: A Systematic Review.

Kalaman, Clarisse Roswini; Ibrahim, Norhayati; Shaker, Vinorra; Cham, Choy Qing; Ho, Meng Chuan; Visvalingam, Uma; Shahabuddin, Farah Ahmad; Abd Rahman, Fairuz Nazri; A Halim, Mohd Radzi Tarmizi; Kaur, Manveen; Azhar, Fatin Liyana; Yahya, Amira Najiha; Sham, Rohana; Siau, Ching Sin; Lee, Kai Wei

Medication adherence, especially among children and adolescents with psychiatric disorders, is often seen as a major treatment challenge. The purpose of this study is to systematically review studies addressing specific aspects of parental factors that are positively or negatively associated with medication adherence among children and adolescents with psychiatric disorders. A systematic literature search of English language publications, from inception through December 2021, was conducted from PubMed, Scopus, and MEDLINE databases. This review has complied with Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines. A total of 23 studies (77,188 participants) met inclusion criteria. Nonadherence rates ranged between 8% to 69%. Parents' socioeconomic background, family living status and functioning, parents' perception and attitude towards the importance of medication taking in treating psychiatric disorders, and parents' mental health status are significant parental characteristics associated with medication adherence in children and adolescents with psychiatric disorders. In conclusion, by identifying specific parental characteristics related to the medication adherence of children and adolescents with psychiatric disorders, targeted interventions on parents could be developed to guide parents in improving their child's medication adherence.

CLINICAL drug trials; DRUG therapy for psychoses; ONLINE information services; PARENT attitudes; PSYCHIATRIC drugs; SYSTEMATIC reviews; PARENTING; SOCIOECONOMIC factors; DESCRIPTIVE statistics; RESEARCH funding; PATIENT compliance; MEDLINE; FAMILY relations; DATA analysis software; CHILDREN; ADOLESCENCE

Healthcare (2227-9032), 2023, Vol 11, Issue 4, p501

2227-9032

Academic Journal

10.3390/healthcare11040501