Works matching DE "TRIPTOLIDE"

Results: 317

Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation.

Published in:

Angewandte Chemie, 2016, v. 128, n. 39, p. 12214, doi. 10.1002/ange.201606121

By:

He, Qing ‐ Li;
Minn, Il;
Wang, Qiaoling;
Xu, Peng;
Head, Sarah A.;
Datan, Emmanuel;
Yu, Biao;
Pomper, Martin G.;
Liu, Jun O.

Publication type:

Article

Covalent Modification of a Cysteine Residue in the XPB Subunit of the General Transcription Factor TFIIH Through Single Epoxide Cleavage of the Transcription Inhibitor Triptolide.

Published in:

Angewandte Chemie, 2015, v. 127, n. 6, p. 1879, doi. 10.1002/ange.201408817

By:

He, Qing-Li;
Titov, Denis V.;
Li, Jing;
Tan, Minjia;
Ye, Zhaohui;
Zhao, Yingming;
Romo, Daniel;
Liu, Jun O.

Publication type:

Article

Preparation and anti-inflammatory activity of triptolide ethosomes in an erythema model.

Published in:

Journal of Liposome Research, 2010, v. 20, n. 4, p. 297, doi. 10.3109/08982100903544144

By:

Chen, Jin-Guang;
Liu, Yu-Feng;
Gao, Tian-Wen

Publication type:

Article

Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 1, p. 43, doi. 10.1111/bcpt.13880

By:

Huang, Yao;
Ba, Xin;
Wang, Hui;
Shen, Pan;
Han, Liang;
Lin, Weiji;
Yan, Jiahui;
Chen, Zhe;
Tu, Shenghao

Publication type:

Article

Evidence for Involvement of Spinal RANTES in the Antinociceptive Effects of Triptolide, a Diterpene Triepoxide, in a Rat Model of Bone Cancer Pain.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 115, n. 6, p. 477, doi. 10.1111/bcpt.12265

By:

Hang, Li‐Hua;
Li, Shu‐Na;
Shao, Dong‐Hua;
Chen, Zheng;
Chen, Yuan‐Feng;
Shu, Wei‐Wei

Publication type:

Article

MYC2 Transcription Factors TwMYC2a and TwMYC2b Negatively Regulate Triptolide Biosynthesis in Tripterygium wilfordii Hairy Roots.

Published in:

Plants (2223-7747), 2021, v. 10, n. 4, p. 679, doi. 10.3390/plants10040679

By:

Huo, Yanbo;
Zhang, Jing;
Zhang, Bin;
Chen, Ling;
Zhang, Xing;
Zhu, Chuanshu

Publication type:

Article

LED Lights Affecting Morphogenesis and Isosteroidal Alkaloid Contents in Fritillaria cirrhosa D. Don—An Important Chinese Medicinal Herb.

Published in:

Plants (2223-7747), 2020, v. 9, n. 10, p. 1351, doi. 10.3390/plants9101351

By:

Chen, Chia-Chen;
Lee, Maw-Rong;
Wu, Chi-Rei;
Ke, Hsin-Ju;
Xie, Hui-Min;
Tsay, Hsin-Sheng;
Agrawal, Dinesh Chandra;
Chang, Hung-Chi

Publication type:

Article

Triptolide inhibits matrix metalloproteinase-9 expression and invasion of breast cancer cells through the inhibition of NF-κB and AP-1 signaling pathways.

Published in:

Oncology Letters, 2021, v. 22, n. 1, p. N.PAG, doi. 10.3892/ol.2021.12823

By:

Hong, On-Yu;
Jang, Hye-Yeon;
Park, Kwang-Hyun;
Jeong, Young-Ju;
Kim, Jong-Suk;
Chae, Hee Suk

Publication type:

Article

Triptolide inhibits human telomerase reverse transcriptase by downregulating translation factors SP1 and c-Myc in Epstein-Barr virus-positive B lymphocytes.

Published in:

Oncology Letters, 2021, v. 21, n. 4, p. N.PAG, doi. 10.3892/ol.2021.12541

By:

Long, Cong;
Xu, Qiu-Bo;
Ding, Li;
Yang, Liu;
Ji, Wei;
Gao, Feng;
Ji, Yong

Publication type:

Article

Triptolide suppresses the proliferation and induces the apoptosis of nasopharyngeal carcinoma cells via the PI3K/Akt pathway.

Published in:

Oncology Letters, 2019, v. 17, n. 1, p. 1372

By:

Wang, Mi;
Chen, Bo;
Chai, Liang

Publication type:

Article

Triptolide induces protective autophagy and apoptosis in human cervical cancer cells by downregulating Akt/mTOR activation.

Published in:

Oncology Letters, 2018, v. 16, n. 3, p. 3929, doi. 10.3892/ol.2018.9074

By:

Qin, Guangyi;
Li, Ping;
Xue, Zhuowei

Publication type:

Article

Triptolide induces DNA breaks, activates caspase-3-dependent apoptosis and sensitizes B-cell lymphoma to poly(ADP-ribose) polymerase 1 and phosphoinositide 3-kinase inhibitors.

Published in:

Oncology Letters, 2017, v. 14, n. 4, p. 4965, doi. 10.3892/ol.2017.6771

By:

JIAWEI GUAN;
QIAN ZHAO;
JIAN LV;
ZHIWEI ZHANG;
SHIJIE SUN;
WEIFENG MAO

Publication type:

Article

Triptolide exerts pro-apoptotic and cell cycle arrest activity on drug-resistant human lung cancer A549/Taxol cells via modulation of MAPK and PI3K/Akt signaling pathways.

Published in:

Oncology Letters, 2016, v. 12, n. 5, p. 3586, doi. 10.3892/ol.2016.5099

By:

CHEN QIONG XIE;
PING ZHOU;
JIAN ZUO;
XIANG LI;
YONG CHEN;
JIAN WEI CHEN

Publication type:

Article

Synergistic antitumor activity of gemcitabine combined with triptolide in pancreatic cancer cells.

Published in:

Oncology Letters, 2016, v. 11, n. 5, p. 3527, doi. 10.3892/ol.2016.4379

By:

ZHIXIN QIAO;
MIN HE;
MU HE;
WEIJING LI;
XUANLIN WANG;
YANBING WANG;
QIYUAN KUAI;
CHANGLAN LI;
SUPING REN;
QUN YU

Publication type:

Article

Triptolide avoids cisplatin resistance and induces apoptosis via the reactive oxygen species/nuclear factor-KB pathway in SKOV3<sup>PT</sup> platinum-resistant human ovarian cancer cells.

Published in:

Oncology Letters, 2013, v. 6, n. 4, p. 1084, doi. 10.3892/ol.2013.1524

By:

YAN-YING ZHONG;
HE-PING CHEN;
BU-ZHEN TAN;
HAI-HONG YU;
XIAO-SHAN HUANG

Publication type:

Article

Triptolide Attenuates Vascular Calcification by Upregulating Expression of miRNA-204.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.581230

By:

Pei, Yu-qiang;
Zheng, Yong-qiu;
Ding, Yao-dong;
Xu, Qi-xiang;
Cao, Di;
Wu, Ya-ning;
Wang, Rui;
Yang, Jia-xin;
Liang, Jing;
Ma, Qian;
Ge, Hai-long

Publication type:

Article

Effect of Triptolide on Temporal Expression of Cell Cycle Regulators During Cardiac Hypertrophy.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.566938

By:

Li, Jing-Mei;
Pan, Xi-Chun;
Ding, Yuan-Yuan;
Tong, Yang-Fei;
Chen, Xiao-Hong;
Liu, Ya;
Zhang, Hai-Gang

Publication type:

Article

High-Throughput Metabolomics Method for Discovering Metabolic Biomarkers and Pathways to Reveal Effects and Molecular Mechanism of Ethanol Extract From Epimedium Against Osteoporosis.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01318

By:

Zhao, Jun-feng;
Xu, Jian-yu;
Xu, Yi-er;
Chen, Shui-lin;
Guo, Yan-xing;
Gao, Quan-yang;
Sun, Gui-cai

Publication type:

Article

Berberine Ameliorates Subarachnoid Hemorrhage Injury via Induction of Sirtuin 1 and Inhibiting HMGB1/Nf-κB Pathway.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.01073

By:

Zhang, Xiang-Hua;
Peng, Lei;
Zhang, Jing;
Dong, Yi-Peng;
Wang, Cheng-Jun;
Liu, Cang;
Xia, Da-Yong;
Zhang, Xiang-Sheng

Publication type:

Article

Skimmin Improves Insulin Resistance via Regulating the Metabolism of Glucose: In Vitro and In Vivo Models.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00540

By:

Zhang, Guoqiang;
Cai, Xin;
He, Lingmin;
Qin, Dingmei;
Li, Hongwen;
Fan, Xiaoming

Publication type:

Article

Effect of Triptolide on Dextran Sodium Sulfate-Induced Ulcerative Colitis and Gut Microbiota in Mice.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2019.01652

By:

Wu, Hao;
Rao, Quan;
Ma, Guang-Chao;
Yu, Xiao-Hong;
Zhang, Cong-En;
Ma, Zhi-Jie

Publication type:

Article

Terlipressin Versus Norepinephrine for Septic Shock: A Systematic Review and Meta-Analysis.

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01492

By:

Huang, Po;
Guo, Yuhong;
Li, Bo;
Liu, Qingquan

Publication type:

Article

Application and Mechanisms of Triptolide in the Treatment of Inflammatory Diseases—A Review.

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01469

By:

Yuan, Kai;
Li, Xiaohong;
Lu, Qingyi;
Zhu, Qingqing;
Jiang, Haixu;
Wang, Ting;
Huang, Guangrui;
Xu, Anlong

Publication type:

Article

Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy.

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01219

By:

Zou, Fang;
Wang, Ling;
Liu, Han;
Wang, Wei;
Hu, Longlong;
Xiong, Xiaoying;
Wu, Lijuan;
Shen, Yunfeng;
Yang, Renqiang

Publication type:

Article

<sup>1</sup>H NMR-Based Metabolomics Reveals the Antitumor Mechanisms of Triptolide in BALB/c Mice Bearing CT26 Tumors.

Published in:

Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.01175

By:

Li, Cheng;
Li, Zhongfeng;
Zhang, Tianjiao;
Wei, Peihuang;
Li, Nuo;
Zhang, Wei;
Ding, Xia;
Li, Jian

Publication type:

Article

Improved Retinal Ganglion Cell Survival through Retinal Microglia Suppression by a Chinese Herb Extract, Triptolide, in the DBA/2J Mouse Model of Glaucoma.

Published in:

Ocular Immunology & Inflammation, 2013, v. 21, n. 5, p. 378, doi. 10.3109/09273948.2013.806989

By:

Yang, Fan;
Wu, Lingling;
Guo, Xiujuan;
Wang, Dongmei;
Li, Ying

Publication type:

Article

Immunosuppressive, anti-inflammatory and anti-cancer properties of triptolide: A mini review.

Published in:

Avicenna Journal of Phytomedicine, 2016, v. 6, n. 2, p. 149

By:

Ziaei, Samira;
Halaby, Reginald

Publication type:

Article

Superior in vitro anticancer effect of biomimetic paclitaxel and triptolide co-delivery system in gastric cancer.

Published in:

Journal of Biomedical Research, 2021, v. 35, n. 4, p. 327, doi. 10.7555/JBR.35.20210102

By:

Siwan Wang;
Hui Jiang;
Jia Wang;
Haisi Wu;
Ting Wu;
Mengnan Ni;
Qianqian Zhao;
You Ji;
Ziting Zhang;
Chunming Tang;
Huae Xu

Publication type:

Article

APPLICATION OF PROBABILITYBASEDMULTI - OBJECTIVE OPTIMIZATIONINTHE PREPARATION OF DRUGENCAPSULATION WITH A DESIGNEDEXPERIMENT.

Published in:

Military Technical Courier / Vojnotehnicki Glasnik, 2022, v. 70, n. 4, p. 924, doi. 10.5937/vojtehg70-38011

By:

Jie Yu;
Maosheng Zheng

Publication type:

Article

Antitumor Effect of Triptolide in T-Cell Lymphoblastic Lymphoma by Inhibiting Cell Viability, Invasion, and Epithelial–Mesenchymal Transition via Regulating the PI3K/AKT/mTOR Pathway [Retraction].

Published in:

2024

By:

Huang, Yan;
Wu, Sun;
Zhang, Yuan;
Wang, Lihua;
Guo, Yan

Publication type:

Correction Notice

Antitumor effect of triptolide in T-cell lymphoblastic lymphoma by inhibiting cell viability, invasion, and epithelial-mesenchymal transition via regulating the PI3K/AKT/mTOR pathway.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 769, doi. 10.2147/OTT.S149788

By:

Huang, Yan;
Wu, Sun;
Zhang, Yuan;
Wang, Lihua;
Guo, Yan

Publication type:

Article

Hypolimnetic oxygen depletion rates in deep lakes: Effects of trophic state and organic matter accumulation.

Published in:

Limnology & Oceanography, 2020, v. 65, n. 12, p. 3128, doi. 10.1002/lno.11578

By:

Steinsberger, Thomas;
Schwefel, Robert;
Wüest, Alfred;
Müller, Beat

Publication type:

Article

Pharmacokinetics, distribution and efficacy of triptolide PLGA microspheres after intra-articular injection in a rat rheumatoid arthritis model.

Published in:

Xenobiotica, 2021, v. 51, n. 6, p. 703, doi. 10.1080/00498254.2021.1923860

By:

Wang, Lijuan;
Che, Keke;
Liu, Yan

Publication type:

Article

Dihydromyricetin affect the pharmacokinetics of triptolide in rats.

Published in:

Xenobiotica, 2020, v. 50, n. 3, p. 332, doi. 10.1080/00498254.2019.1616851

By:

Deng, Yang;
Guo, Lin;
Cai, Hualin;
Chen, Lei;
Tan, Shenglan;
Zhang, Bikui;
Fang, Pingfei;
Xiang, Daxiong;
Li, Huande;
He, Guixia;
Yan, Miao

Publication type:

Article

Effects of triptolide on pharmacokinetics of fenofibrate in rats and its potential mechanism.

Published in:

Xenobiotica, 2019, v. 49, n. 2, p. 211, doi. 10.1080/00498254.2018.1438685

By:

Li, Tonghui;
Liu, Jijun;
Zheng, Yingying;
Yang, Shengchang;
Liu, Xun;
Li, Xuejing

Publication type:

Article

Triptolide restrains the growth, invasion, stemness, and glycolysis of non‐small cell lung cancer cells by PFKFB2‐mediated PI3K/AKT pathway.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 1, p. 1, doi. 10.1111/cbdd.14450

By:

Ren, Jiankun;
Zhao, Songwei;
Lai, Junyu

Publication type:

Article

Triptolide inhibits proliferation and invasion of colorectal cancer cells by blocking Nrf2 expression.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 1, p. 1, doi. 10.1111/cbdd.14410

By:

Wang, Hui‐feng;
Zhao, Zhi‐long

Publication type:

Article

Triptolide induces apoptotic cell death of human cholangiocarcinoma cells through inhibition of myeloid cell leukemia-1.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-271

By:

Xiwei Ding;
Bin Zhang;
Qingshan Pei;
Jianmei Pan;
Shuling Huang;
Yan Yang;
Zhu Zhu;
Ying Lv;
Xiaoping Zou

Publication type:

Article

Triptolide induces apoptotic cell death of human cholangiocarcinoma cells through inhibition of myeloid cell leukemia-1.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-271

By:

Xiwei Ding;
Bin Zhang;
Qingshan Pei;
Jianmei Pan;
Shuling Huang;
Yan Yang;
Zhu Zhu;
Ying Lv;
Xiaoping Zou

Publication type:

Article

Helical Polyisocyanopeptides as Lyotropic Liquid Crystals for Measuring Residual Dipolar Couplings.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 32, p. 7653, doi. 10.1002/chem.201700539

By:

Li, Gao‐Wei;
Cao, Jiang‐Ming;
Zong, Wen;
Hu, Li;
Hu, Mao‐Lin;
Lei, Xinxiang;
Sun, Han;
Tan, Ren Xiang

Publication type:

Article

Triptolide triggers the apoptosis of pancreatic cancer cells via the downregulation of Decoy receptor 3 expression.

Published in:

Journal of Cancer Research & Clinical Oncology, 2012, v. 138, n. 9, p. 1597, doi. 10.1007/s00432-012-1235-x

By:

Wang, Wei;
Li, Xinfeng;
Sun, Weimin;
Zhang, Lurong;
Zhang, Mei;
Hong, Benzu;
Lv, Guorong

Publication type:

Article

雷公藤甲素调节小胶质细胞极化反应保护损伤的神经元.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2023, v. 27, n. 33, p. 5342, doi. 10.12307/2023.723

By:

张慧宇;
于婧文;
白振军;
李亮;
穆秉桃;
张金锋;
解佳伟

Publication type:

Article

Effectiveness and safety of tripterygium wilfordii poly-glycosides on glomerulonephritis: a systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1339153

By:

Xiaolin Yan;
Juan Shi;
Yingying Zhang;
Juan Liu;
Xiaoqing Lin;
Chungang Yu;
Xiao Li

Publication type:

Article

Network pharmacology and experiment validation investigate the potential mechanism of triptolide in oral squamous cell carcinoma.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1302059

By:

Puyu Hao;
Pengcheng Zhang;
Ying Liu;
Yang Cao;
Lianqun Du;
Li Gao;
Qingyang Dong

Publication type:

Article

Triptolide Upregulates Myocardial Forkhead Helix Transcription Factor p3 Expression and Attenuates Cardiac Hypertrophy.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00471

By:

Yuan-Yuan Ding;
Jing-Mei Li;
Feng-Jie Guo;
Ya Liu;
Yang-Fei Tong;
Xi-Chun Pan;
Xiao-Lan Lu;
Wen Ye;
Xiao-Hong Chen;
Hai-Gang Zhang

Publication type:

Article

Effect of Adoptive Transfer or Depletion of Regulatory T Cells on Triptolide-induced Liver Injury.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00099

By:

Xinzhi Wang;
Lixin Sun;
Luyong Zhang;
Zhenzhou Jiang;
Wenye, Geng;
Jian Li

Publication type:

Article

Sex-Related Differences of Lipid Metabolism Induced by Triptolide: The Possible Role of the LXRα/SREBP-1 Signaling Pathway.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00087

By:

Zhenzhou Jiang;
Xiao Huang;
Shan Huang;
Hongli Guo;
Lu Wang;
Xiaojiaoyang Li;
Xin Huang;
Tao Wang;
Luyong Zhang;
Lixin Sun

Publication type:

Article

Attenuating heat-induced cellular autophagy, apoptosis and damage in H9c2 cardiomyocytes by pre-inducing HSP70 with heat shock preconditioning.

Published in:

International Journal of Hyperthermia, 2013, v. 29, n. 3, p. 239, doi. 10.3109/02656736.2013.777853

By:

Hsu, Shu-Fen;
Chao, Chien-Ming;
Huang, Wu-Tein;
Lin, Mao-Tsun;
Cheng, Bor-Chih

Publication type:

Article

The mechanism of triptolide in the treatment of connective tissue disease-related interstitial lung disease based on network pharmacology and molecular docking.

Published in:

Annals of Medicine, 2022, v. 54, n. 1, p. 541, doi. 10.1080/07853890.2022.2034931

By:

Zhu, Wen;
Li, Yehui;
Zhao, Junjie;
Wang, Yifan;
Li, Yixi;
Wang, Yue

Publication type:

Article

Triptolide Preserves Cognitive Function and Reduces Neuropathology in a Mouse Model of Alzheimer's Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0108845

By:

Cheng, Shaowu;
LeBlanc, Kyle J.;
Li, Ling

Publication type:

Article