Works matching DE "GENETIC load"

Results: 651

Research Highlights.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1126, doi. 10.1038/nsmb1207-1126

By:

Konforti, Boyana;
Lall, Sabbi;
Montoya, Michelle

Publication type:

Article

A Nonadaptive Origin of a Beneficial Trait: In Silico Selection for Free Energy of Folding Leads to the Neutral Emergence of Mutational Robustness in Single Domain Proteins.

Published in:

Journal of Molecular Evolution, 2014, v. 78, n. 2, p. 130, doi. 10.1007/s00239-013-9606-8

By:

Pagan, Rafael;
Massey, Steven

Publication type:

Article

The C9ORF72 expansion mutation: gene structure, phenotypic and diagnostic issues.

Published in:

Acta Neuropathologica, 2014, v. 127, n. 3, p. 319, doi. 10.1007/s00401-014-1253-7

By:

Woollacott, Ione;
Mead, Simon

Publication type:

Article

Mechanisms of toxicity in C9FTLD/ALS.

Published in:

Acta Neuropathologica, 2014, v. 127, n. 3, p. 359, doi. 10.1007/s00401-013-1237-z

By:

Gendron, Tania;
Belzil, Veronique;
Zhang, Yong-Jie;
Petrucelli, Leonard

Publication type:

Article

The complete linkage disequilibrium test: a test that points to causative mutations underlying quantitative traits.

Published in:

Genetics Selection Evolution, 2011, v. 43, n. 5, p. 1, doi. 10.1186/1297-9686-43-20

By:

Uleberg, Eivind;
Meuwissen, Theo H. E.

Publication type:

Article

Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans.

Published in:

Nature, 2014, v. 508, n. 7494, p. 128, doi. 10.1038/nature13012

By:

Shen, En-Zhi;
Song, Chun-Qing;
Lin, Yuan;
Zhang, Wen-Hong;
Su, Pei-Fang;
Liu, Wen-Yuan;
Zhang, Pan;
Xu, Jiejia;
Lin, Na;
Zhan, Cheng;
Wang, Xianhua;
Shyr, Yu;
Cheng, Heping;
Dong, Meng-Qiu

Publication type:

Article

Olympics: Genetically enhanced Olympics are coming.

Published in:

Nature, 2012, v. 487, n. 7407, p. 297, doi. 10.1038/487297a

By:

Enriquez, Juan;
Gullans, Steve

Publication type:

Article

Comprehensive molecular characterization of human colon and rectal cancer.

Published in:

Nature, 2012, v. 487, n. 7407, p. 330, doi. 10.1038/nature11252

By:

Muzny, Donna M.;
Bainbridge, Matthew N.;
Chang, Kyle;
Dinh, Huyen H.;
Drummond, Jennifer A.;
Fowler, Gerald;
Kovar, Christie L.;
Lewis, Lora R.;
Morgan, Margaret B.;
Newsham, Irene F.;
Reid, Jeffrey G.;
Santibanez, Jireh;
Shinbrot, Eve;
Trevino, Lisa R.;
Wu, Yuan-Qing;
Wang, Min;
Gunaratne, Preethi;
Donehower, Lawrence A.;
Creighton, Chad J.;
Wheeler, David A.

Publication type:

Article

Should We Really Say Goodbye to the Effects of Nurture on Development?

Published in:

Alpha Psychiatry, 2024, v. 25, n. 6, p. 746, doi. 10.5152/alphapsychiatry.2024.241819

By:

Koot, Hans M.

Publication type:

Article

On the Inclusion of Adaptive Potential in Species Distribution Models: Towards a Genomic-Informed Approach to Forest Management and Conservation.

Published in:

Environments (2076-3298), 2023, v. 10, n. 1, p. 3, doi. 10.3390/environments10010003

By:

Vajana, Elia;
Bozzano, Michele;
Marchi, Maurizio;
Piotti, Andrea

Publication type:

Article

Colorectal cancer and endoplasmic reticulum stress - potential targets for therapeutic compounds.

Published in:

Journal of Pre-Clinical & Clinical Research, 2024, v. 18, n. 1, p. 54, doi. 10.26444/jpccr/186030

By:

Augusto Sobrinho, César;
Almeida, Alexandre Moreira;
Selzler, Michele;
Martins, Almir Sousa;
Ramalho, Rondon Tosta;
Batista Palhares, Durval

Publication type:

Article

Evidence for autonomous selfing in grassland Protea species (Proteaceae).

Published in:

Botanical Journal of the Linnean Society, 2012, v. 169, n. 3, p. 433, doi. 10.1111/j.1095-8339.2012.01243.x

By:

STEENHUISEN, SANDY-LYNN;
JOHNSON, STEVEN D.

Publication type:

Article

CPAN - A novel transdiagnostic dimensional approach to the assessment of psychotic disorders.

Published in:

2024

By:

Hermán, L.;
Réthelyi, J. M.;
Tolna, J.;
Komoróczy, E.;
Császár, I. B.;
Baradits, M.

Publication type:

Abstract

Rates of perinatal environment risk factors in schizophrenia patients with higher and lower schizophrenia polygenic risk scores.

Published in:

2024

By:

Alfimova, M.;
Gabaeva, M.;
Lezheiko, T.;
Plakunova, V.;
Golimbet, V.

Publication type:

Abstract

Modeling the appearance and progression of cognitive impairment.

Published in:

European Psychiatry, 2021, v. 64, p. S138, doi. 10.1192/j.eurpsy.2021.381

By:

Mainguy, B.;
Mehl-Madrona, L.;
Ruben, D.

Publication type:

Article

Profiling for Alcohol Addiction.

Published in:

European Psychiatry, 2015, v. 30, p. 1065, doi. 10.1016/S0924-9338(15)30840-3

By:

Papava, I.;
Bredicean, A.C.;
Enatescu, V.R.;
Dehelean, L.;
Romosan, F.;
Popescu, A.L.;
Vrabie, A.E.

Publication type:

Article

P-291 - Characteristics of autism spectrum disorders in non-twin brothers

Published in:

2012

By:

González Saavedra, L.;
Tellez, J.M.G.;
Lea, J.M.S.M.

Publication type:

Abstract

Molecular Characterization and Comparative Genomics of IncQ-3 Plasmids Conferring Resistance to Various Antibiotics Isolated from a Wastewater Treatment Plant in Warsaw (Poland).

Published in:

Antibiotics (2079-6382), 2020, v. 9, n. 9, p. 613, doi. 10.3390/antibiotics9090613

By:

Piotrowska, Marta;
Dziewit, Lukasz;
Ostrowski, Rafał;
Chmielowska, Cora;
Popowska, Magdalena

Publication type:

Article

Genomic consequences of population decline in critically endangered pangolins and their demographic histories.

Published in:

National Science Review, 2020, v. 7, n. 4, p. 798, doi. 10.1093/nsr/nwaa031

By:

Hu, Jing-Yang;
Hao, Zi-Qian;
Frantz, Laurent;
Wu, Shi-Fang;
Chen, Wu;
Jiang, Yun-Fang;
Wu, Hong;
Kuang, Wei-Min;
Li, Haipeng;
Zhang, Ya-Ping;
Yu, Li

Publication type:

Article

Genetic load and biological changes to extant humans.

Published in:

2021

By:

Saniotis, Arthur;
Henneberg, Maciej;
Mohammadi, Kazhaleh

Publication type:

journal article

Is lack of evidence of inbreeding depression in a threatened New Zealand robin indicative of reduced genetic load?

Published in:

Animal Conservation, 2011, v. 14, n. 1, p. 47, doi. 10.1111/j.1469-1795.2010.00388.x

By:

Laws, R. J.;
Jamieson, I. G.

Publication type:

Article

Research on the Influence of Genetic Algorithm Parameters on XGBoost in Load Forecasting.

Published in:

Engineering, Technology & Applied Science Research, 2024, v. 14, n. 6, p. 18849, doi. 10.48084/etasr.8863

By:

Thanh-Ngoc Tran;
Quoc-Dai Nguyen

Publication type:

Article

ALTERAÇÕES CITOGENÉTICAS EM CRIANÇAS RESIDENTES EM REGIÕES ECOLOGICAMENTE ADVERSAS DO CAZAQUISTÃO.

Published in:

Periódico Tchê Química, 2020, v. 17, n. 35, p. 1137

By:

BAKHTIYAROVA, Sholpan;
ZHAKSYMOV, Bolatbek;
KAPYSHEVA, Unzira;
CHEREDNICHENKO, Oksana

Publication type:

Article

Virtualized intelligent genetic load balancer for federated hybrid cloud environment using deep belief network classifier.

Published in:

Journal of Cloud Computing (2192-113X), 2023, v. 12, n. 1, p. 1, doi. 10.1186/s13677-023-00514-7

By:

Rajkumar, S.;
Katiravan, Jeevaa

Publication type:

Article

Accounting for the genetic load in assisted reproductive technology.

Published in:

Clinical & Translational Medicine, 2022, v. 12, n. 5, p. 1, doi. 10.1002/ctm2.864

By:

van Oosterhout, Cock;
Marcu, Daniel;
Immler, Simone

Publication type:

Article

Inbreeding effects on progeny sex ratio and gender variation in the gynodioecious Silene vulgaris (Caryophyllaceae).

Published in:

New Phytologist, 2006, v. 172, n. 4, p. 763, doi. 10.1111/j.1469-8137.2006.01866.x

By:

Glaettli, Mélanie;
Goudet, Jérôme

Publication type:

Article

Evolution under tight linkage to mating type.

Published in:

New Phytologist, 2005, v. 165, n. 1, p. 63, doi. 10.1111/j.1469-8137.2004.01246.x

By:

Uyenoyama, Marcy K.

Publication type:

Article

Abiotic stress does not magnify the deleterious effects of spontaneous mutations.

Published in:

Heredity, 2015, v. 115, n. 6, p. 503, doi. 10.1038/hdy.2015.51

By:

Andrew, J R;
Dossey, M M;
Garza, V O;
Keller-Pearson, M;
Baer, C F;
Joyner-Matos, J

Publication type:

Article

On the consequences of ignoring purging on genetic recommendations for minimum viable population rules.

Published in:

Heredity, 2015, v. 115, n. 3, p. 185, doi. 10.1038/hdy.2015.28

By:

García-Dorado, A

Publication type:

Article

Hereditary mixed polyposis syndrome due to a BMPR1A mutation.

Published in:

Colorectal Disease, 2010, v. 12, n. 6, p. 570, doi. 10.1111/j.1463-1318.2009.01931.x

By:

O'Riordan, J. M.;
O'Donoghue, D.;
Green, A.;
Keegan, D.;
Hawkes, L. A.;
Payne, S. J.;
Sheahan, K.;
Winter, D. C.

Publication type:

Article

Pre-treatment non-ictal cephalic allodynia identifies responders to prophylactic treatment of chronic and episodic migraine patients with galcanezumab: A prospective quantitative sensory testing study (NCT04271202).

Published in:

Cephalalgia, 2023, v. 43, n. 3, p. 1, doi. 10.1177/03331024221147881

By:

Ashina, Sait;
Melo-Carrillo, Agustin;
Szabo, Edina;
Borsook, David;
Burstein, Rami

Publication type:

Article

Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2007, v. 32, n. 5, p. 505, doi. 10.1111/j.1365-2710.2007.00850.x

By:

Li, D.;
Lu, W.;
Zhu, J.-Y.;
Gao, J.;
Lou, Y.-Q.;
Zhang, G.-L.

Publication type:

Article

Pan-cancer analysis of the prognostic and immunological role of GJB2: a potential target for survival and immunotherapy.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1110207

By:

Yuting Jia;
Bin Guo;
Wenbin Zhang;
Feng Wang;
Yong Zhang;
Quanmao Zhang;
Erfeng Li

Publication type:

Article

Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1171926

By:

Shujie Zeng;
Zihao Zhang;
Chunshui Ye;
Jinshen Wang;
Changqing Jing;
Leping Li

Publication type:

Article

Mitochondrial metabolic reprogramming-mediated immunogenic cell death reveals immune and prognostic features of clear cell renal cell carcinoma.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1146657

By:

Lin Yang;
Jing Xiong;
Sheng Li;
Xiaoqiang Liu;
Wen Deng;
Weipeng Liu;
Bin Fu

Publication type:

Article

A Novel Nonsense Mutation (c.414G>A; p.Trp138*) in CLDN14 Causes Hearing Loss in Yemeni Families: A Case Report.

Published in:

Frontiers in Genetics, 2019, v. 10, p. 1, doi. 10.3389/fgene.2019.01087

By:

Mohamed, Walaa Kamal Eldin;
Mahfood, Mona;
Al Mutery, Abdullah;
Abdallah, Sallam Hasan;
Tlili, Abdelaziz

Publication type:

Article

Atypical phenotype of type I Bartter syndrome accompanied by focal segmental glomerulosclerosis.

Published in:

2009

By:

Yamazaki, Hajime;
Nozu, Kandai;
Narita, Ichiei;
Nagata, Michio;
Nozu, Yoshimi;
Fu, Xue;
Matsuo, Masafumi;
Iijima, Kazumoto;
Gejyo, Fumitake

Publication type:

Report

Somatic mutation profiles as molecular classifiers of ulcerative colitis‐associated colorectal cancer.

Published in:

International Journal of Cancer, 2021, v. 148, n. 12, p. 2997, doi. 10.1002/ijc.33492

By:

Mäki‐Nevala, Satu;
Ukwattage, Sanjeevi;
Olkinuora, Alisa;
Almusa, Henrikki;
Ahtiainen, Maarit;
Ristimäki, Ari;
Seppälä, Toni;
Lepistö, Anna;
Mecklin, Jukka‐Pekka;
Peltomäki, Päivi

Publication type:

Article

Distinct immune evasion in APOBEC‐enriched, HPV‐negative HNSCC.

Published in:

International Journal of Cancer, 2020, v. 147, n. 8, p. 2293, doi. 10.1002/ijc.33123

By:

Messerschmidt, Clemens;
Obermayer, Benedikt;
Klinghammer, Konrad;
Ochsenreither, Sebastian;
Treue, Denise;
Stenzinger, Albrecht;
Glimm, Hanno;
Fröhling, Stefan;
Kindler, Thomas;
Brandts, Christian H.;
Schulze‐Osthoff, Klaus;
Weichert, Wilko;
Tinhofer, Ingeborg;
Klauschen, Frederick;
Keilholz, Ulrich;
Beule, Dieter;
Rieke, Damian T.

Publication type:

Article

Somatic genome alterations in relation to age in lung adenocarcinoma.

Published in:

International Journal of Cancer, 2019, v. 145, n. 8, p. 2091, doi. 10.1002/ijc.32265

By:

Meucci, Stefano;
Keilholz, Ulrich;
Heim, Daniel;
Klauschen, Frederick;
Cacciatore, Stefano

Publication type:

Article

A point mutation in recC associated with subclonal replacement of carbapenem-resistant Klebsiella pneumoniae ST11 in China.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38061-z

By:

Zhou, Kai;
Xue, Chun-Xu;
Xu, Tingting;
Shen, Ping;
Wei, Sha;
Wyres, Kelly L.;
Lam, Margaret M. C.;
Liu, Jinquan;
Lin, Haoyun;
Chen, Yunbo;
Holt, Kathryn E.;
Ding, Hui;
Liu, Yongyun;
Mao, Haifeng;
Huang, Ying;
Yang, Zhenghai;
Dai, Yuanyuan;
Liao, Guolin;
Zhu, Lisha;
Zhang, Liping

Publication type:

Article

Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36769-6

By:

Calsina, Bruna;
Piñeiro-Yáñez, Elena;
Martínez-Montes, Ángel M.;
Caleiras, Eduardo;
Fernández-Sanromán, Ángel;
Monteagudo, María;
Torres-Pérez, Rafael;
Fustero-Torre, Coral;
Pulgarín-Alfaro, Marta;
Gil, Eduardo;
Letón, Rocío;
Jiménez, Scherezade;
García-Martín, Santiago;
Martin, Maria Carmen;
Roldán-Romero, Juan María;
Lanillos, Javier;
Mellid, Sara;
Santos, María;
Díaz-Talavera, Alberto;
Rubio, Ángeles

Publication type:

Article

Impacts of Population Size and Domestication Process on Genetic Diversity and Genetic Load in Genus Ovis.

Published in:

Genes, 2023, v. 14, n. 10, p. 1977, doi. 10.3390/genes14101977

By:

Wang, Dongfeng;
Salehian-Dehkordi, Hosein;
Suo, Langda;
Lv, Fenghua

Publication type:

Article

Genetic Aspects of Conjunctival Melanoma: A Review.

Published in:

Genes, 2023, v. 14, n. 9, p. 1668, doi. 10.3390/genes14091668

By:

Chang, Emily;
Demirci, Hakan;
Demirci, F. Yesim

Publication type:

Article

The Ribosomal Protein RpL22 Interacts In Vitro with 5′-UTR Sequences Found in Some Drosophila melanogaster Transposons.

Published in:

Genes, 2022, v. 13, n. 2, p. 305, doi. 10.3390/genes13020305

By:

Minervini, Crescenzio Francesco;
Berloco, Maria Francesca;
Marsano, René Massimiliano;
Viggiano, Luigi

Publication type:

Article

Targeted Sequencing of Pancreatic Adenocarcinomas from Patients with Metachronous Pulmonary Metastases.

Published in:

Genes, 2020, v. 11, n. 12, p. 1391, doi. 10.3390/genes11121391

By:

Hlavac, Viktor;
Mohelnikova-Duchonova, Beatrice;
Lovecek, Martin;
Ehrmann, Jiri;
Brynychova, Veronika;
Kolarova, Katerina;
Soucek, Pavel

Publication type:

Article

SNP-Based Genetic Risk Score Modeling Suggests No Increased Genetic Susceptibility of the Roma Population to Type 2 Diabetes Mellitus.

Published in:

Genes, 2019, v. 10, n. 11, p. 942, doi. 10.3390/genes10110942

By:

Werissa, Nardos Abebe;
Piko, Peter;
Fiatal, Szilvia;
Kosa, Zsigmond;
Sandor, Janos;
Adany, Roza

Publication type:

Article

Origin and Evolution of Deleterious Mutations in Horses.

Published in:

Genes, 2019, v. 10, n. 9, p. 649, doi. 10.3390/genes10090649

By:

Orlando, Ludovic;
Librado, Pablo

Publication type:

Article

On the Population Dynamics of Junk: A Review on the Population Genomics of Transposable Elements.

Published in:

Genes, 2019, v. 10, n. 6, p. 419, doi. 10.3390/genes10060419

By:

Bourgeois, Yann;
Boissinot, Stéphane

Publication type:

Article

Reply to Nellen et al's Comment on the Classification of Clinical/genetic Variants of Mal de Meleda.

Published in:

Acta Dermato-Venereologica, 2015, v. 95, n. 8, p. 1034, doi. 10.2340/00015555-2196

By:

Linshu Zhao;
Vahlquist, Anders;
Virtanen, Marie;
Wennerstrand, Lena;
Lind, Lisbet K.;
Lundström, Anita;
Hellström Pigg, Maritta

Publication type:

Article