Results
Title

The Added Value of [ 18 F]FDG PET/CT in the Management of Invasive Fungal Infections.

Authors

Ankrah, Alfred O.; Creemers-Schild, Dina; de Keizer, Bart; Klein, Hans C.; Dierckx, Rudi A. J. O.; Kwee, Thomas C.; Span, Lambert F. R.; de Jong, Pim A.; Sathekge, Mike M.; Glaudemans, Andor W. J. M.

Abstract

Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [18F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [18F]FDG PET/CT for 94.4% of the scans performed. [18F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [18F]FDG PET/CT added value in the management of the IFIs.

Subjects

NETHERLANDS; COMPUTED tomography; MYCOSES; ULTRASONIC imaging; ACADEMIC medical centers; DIAGNOSTIC imaging

Publication

Diagnostics (2075-4418), 2021, Vol 11, Issue 1, p137

ISSN

2075-4418

Publication type

Academic Journal

DOI

10.3390/diagnostics11010137