Works matching DE "RAS proteins"

Results: 1012

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 46, doi. 10.1038/nsmb.2430

By:

Baker, Rachael;
Lewis, Steven M;
Sasaki, Atsuo T;
Wilkerson, Emily M;
Locasale, Jason W;
Cantley, Lewis C;
Kuhlman, Brian;
Dohlman, Henrik G;
Campbell, Sharon L

Publication type:

Article

Grb-ing hold of insulin signaling.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 8, p. 803, doi. 10.1038/nsmb0809-803

By:

Ceccarelli, Derek F. J.;
Sicheri, Frank

Publication type:

Article

Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 215, doi. 10.1038/nsmb1208

By:

Xia, Mingxuan;
Land, Hartmut

Publication type:

Article

The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 59, p. 1, doi. 10.1002/chem.202201449

By:

Pálfy, Gyula;
Menyhárd, Dóra K.;
Ákontz‐Kiss, Hanna;
Vida, István;
Batta, Gyula;
Tőke, Orsolya;
Perczel, András

Publication type:

Article

Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides.

Published in:

Angewandte Chemie, 2015, v. 127, n. 26, p. 7712, doi. 10.1002/ange.201502763

By:

Upadhyaya, Punit;
Qian, Ziqing;
Selner, Nicholas G.;
Clippinger, Sarah R.;
Wu, Zhengrong;
Briesewitz, Roger;
Pei, Dehua

Publication type:

Article

Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor.

Published in:

Angewandte Chemie, 2014, v. 126, n. 1, p. 203, doi. 10.1002/ange.201307387

By:

Lim, Sang Min;
Westover, Kenneth D.;
Ficarro, Scott B.;
Harrison, Rane A.;
Choi, Hwan Geun;
Pacold, Michael E.;
Carrasco, Martin;
Hunter, John;
Kim, Nam Doo;
Xie, Ting;
Sim, Taebo;
Jänne, Pasi A.;
Meyerson, Matthew;
Marto, Jarrod A.;
Engen, John R.;
Gray, Nathanael S.

Publication type:

Article

In vitro and in vivo toxicity of nano chitosan against Curvularia lunata, the causal microorganism of fruit rot and blight, a new disease of olive (O. europaea L.).

Published in:

European Journal of Plant Pathology, 2021, v. 161, n. 4, p. 881, doi. 10.1007/s10658-021-02371-z

By:

Mohamed, Mazhar D. A.;
Moharam, Moustafa H. A.;
Ahmed, Hoda A. M.

Publication type:

Article

Lipidated peptides via post-synthetic thioalkylation promoted by molecular sieves.

Published in:

Amino Acids, 2014, v. 46, n. 8, p. 1899, doi. 10.1007/s00726-014-1742-y

By:

Calce, Enrica;
Leone, Marilisa;
Monfregola, Luca;
De Luca, Stefania

Publication type:

Article

Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway.

Published in:

Biochemical Journal, 2024, v. 481, n. 6, p. 405, doi. 10.1042/BCJ20240015

By:

Weatherdon, Laura;
Stuart, Kate;
Cassidy, Megan;
de la Gándara, Alberto Moreno;
Okkenhaug, Hanneke;
Muellener, Markus;
Mckenzie, Grahame;
Cook, Simon J.;
Gilley, Rebecca

Publication type:

Article

Dynamic regulation of RAS and RAS signaling.

Published in:

Biochemical Journal, 2023, v. 480, n. 1, p. 1, doi. 10.1042/BCJ20220234

By:

Kolch, Walter;
Berta, Dénes;
Rosta, Edina

Publication type:

Article

RAS Function in cancer cells: translating membrane biology and biochemistry into new therapeutics.

Published in:

Biochemical Journal, 2020, v. 477, n. 15, p. 2893, doi. 10.1042/BCJ20190839

By:

Kattan, Walaa E.;
Hancock, John F.

Publication type:

Article

陶湖杂交F1代与萨湖杂交F1代羔羊背最长肌转录组分析.

Published in:

Feed Research, 2022, v. 45, n. 11, p. 56, doi. 10.13557/j.cnki.issn1002-2813.2022.11.013

By:

王燕燕;
杨军祥;
徐建峰;
成伟伟;
何茂昌;
王珂;
高登伟;
谢文章

Publication type:

Article

Overexpression of SYNGAP1 suppresses the proliferation of rectal adenocarcinoma via Wnt/β-Catenin signaling pathway.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-00997-z

By:

Xiao, Yun;
Zhu, Ying;
Chen, Jiaojiao;
Wu, Mei;
Wang, Lan;
Su, Li;
Feng, Fei;
Hou, Yanli

Publication type:

Article

沙棘熊果酸对H22荷瘤小鼠抑瘤活性及其机制的探讨.

Published in:

Food Research & Development, 2019, v. 40, n. 10, p. 6, doi. 10.3969/j.issn.1005-6521.2019.10.002

By:

张男男;
侯瑞丽;
李可欣;
张文龙;
高龙;
苗晓涵;
戈娜

Publication type:

Article

Single‐Molecule Bioelectronic Label‐Free Assay of both Protein and Genomic Markers of Pancreatic Mucinous Cysts' in Whole Blood Serum.

Published in:

Advanced Electronic Materials, 2021, v. 7, n. 9, p. 1, doi. 10.1002/aelm.202100304

By:

Macchia, Eleonora;
Sarcina, Lucia;
Driescher, Caroline;
Gounani, Zahra;
Tewari, Amit;
Osterbacka, Ronald;
Palazzo, Gerardo;
Tricase, Angelo;
Kovacs Vajna, Zsolt Miklos;
Viola, Fabrizio;
Modena, Francesco;
Caironi, Mario;
Torricelli, Fabrizio;
Esposito, Irene;
Torsi, Luisa

Publication type:

Article

Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1726, doi. 10.3390/jcm8101726

By:

Kalvala, Arjun;
Wallet, Pierre;
Yang, Lu;
Wang, Chongkai;
Li, Haiqing;
Nam, Arin;
Nathan, Anusha;
Mambetsariev, Isa;
Poroyko, Valeriy;
Gao, Hanlin;
Chu, Peiguo;
Sattler, Martin;
Bild, Andrea;
Manuel, Edwin R.;
Lee, Peter P.;
Jolly, Mohit Kumar;
Kulkarni, Prakash;
Salgia, Ravi

Publication type:

Article

Possible modifier genes in the variation of neurofibromatosis type 1 clinical phenotypes.

Published in:

Journal of Neurogenetics, 2018, v. 32, n. 2, p. 65, doi. 10.1080/01677063.2018.1456538

By:

Sharafi, Parisa;
Ayter, Sükriye

Publication type:

Article

Selection of Reference Genes for qRT-PCR Analysis in Medicinal Plant Glycyrrhiza under Abiotic Stresses and Hormonal Treatments.

Published in:

Plants (2223-7747), 2020, v. 9, n. 11, p. 1441, doi. 10.3390/plants9111441

By:

Li, Yuping;
Liang, Xiaoju;
Zhou, Xuguo;
Wu, Zhigeng;
Yuan, Ling;
Wang, Ying;
Li, Yongqing

Publication type:

Article

G12V Kras mutations in cervical cancer under virtual microscope of molecular dynamics simulations.

Published in:

European Journal of Gynaecological Oncology, 2016, v. 37, n. 1, p. 69, doi. 10.12892/ejgo2742.2016

By:

Chen, X. P.;
Xu, W. H.;
Xu, D. F.;
Fu, S. M.;
Ma, Z. C.

Publication type:

Article

RAC/ROP GTPases and Auxin Signaling.

Published in:

Plant Cell, 2011, v. 23, n. 4, p. 1208, doi. 10.1105/tpc.111.083907

By:

Wu, Hen-ming;
Hazak, Ora;
Cheung, Alice Y.;
Yalovsky, Shaul

Publication type:

Article

Pathological features of gastric‑type endocervical adenocarcinoma: A report of two cases.

Published in:

2024

By:

Zhou, Jiahui;
Zhang, Xiangning;
Mao, Weibo;
Zhu, Yiling;
Yan, Liping;
Jiang, Jiangle;
Zhang, Min

Publication type:

Case Study

miR-188-5p promotes oxaliplatin resistance by targeting RASA1 in colon cancer cells.

Published in:

Oncology Letters, 2021, v. 21, n. 6, p. N.PAG, doi. 10.3892/ol.2021.12742

By:

Zhu, Xijia;
Luo, Xishun;
Song, Zhike;
Jiang, Shiyu;
Long, Xiangkai;
Gao, Xueyuan;
Xie, Xinyang;
Zheng, Laijian;
Wang, Haipeng

Publication type:

Article

Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer.

Published in:

Oncology Letters, 2021, v. 21, n. 1, p. N.PAG

By:

Song, Cheng;
Pan, Bo;
Yang, Xiao;
Tang, Wei

Publication type:

Article

miR-130b-5p promotes proliferation, migration and invasion of gastric cancer cells via targeting RASAL1.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 6361, doi. 10.3892/ol.2018.8174

By:

Chen, Hong;
Yang, Yiqiong;
Wang, Jing;
Shen, Duo;
Zhao, Jiyi;
Yu, Qian

Publication type:

Article

RAS protein activator-like 1 is functionally involved in hypoxia resistance in breast cancer cells by targeting hypoxia inducible factor-1α.

Published in:

Oncology Letters, 2017, v. 14, n. 3, p. 3839, doi. 10.3892/ol.2017.6648

By:

Ziming Huang;
Rong Wang;
Gang Wei;
Ran Jiang;
Yuan Zheng;
Yiwen Tian;
Bo Chen;
Chunmei Ye;
Mingxing Xue;
Chunjiao Yu

Publication type:

Article

Alterations in IQGAP1 expression and localization in colorectal carcinoma and liver metastases following oxaliplatin-based chemotherapy.

Published in:

Oncology Letters, 2017, v. 14, n. 3, p. 2621, doi. 10.3892/ol.2017.6525

By:

Rotoli, Deborah;
Morales, Manuel;
Del Carmen Maeso, María;
Del Pino García, María;
Gutierrez, Ricardo;
Valladares, Francisco;
Ávila, Julio;
Díaz-Flores, Lucio;
Mobasheri, Ali;
Martín-Vasallo, Pablo

Publication type:

Article

Ras protein expression as a marker for breast cancer.

Published in:

Oncology Letters, 2016, v. 11, n. 6, p. 3637, doi. 10.3892/ol.2016.4461

By:

CALAF, GLORIA M.;
ABARCA-QUINONES, JORGE

Publication type:

Article

Role of RAS mutation status as a prognostic factor for patients with advanced colorectal cancer treated with first-line chemotherapy based on fluoropyrimidines and oxaliplatin, with or without bevavizumab: A retrospective analysis.

Published in:

Molecular & Clinical Oncology, 2017, v. 6, n. 3, p. 403, doi. 10.3892/mco.2017.1149

By:

NOGUERA, JAVIER GARDE;
JANTUS-LEWINTRE, ELOISA;
GIL-RAGA, MIREIA;
EVGENYEVA, ELENA;
ESCALANTE, SONIA MACIÁ;
LLOMBART-CUSSAC, ANTONIO;
HERRERO, CARLOS CAMPS

Publication type:

Article

Vector-G: Multi-Modular SVM-Based Heterotrimeric G Protein Prediction.

Published in:

In Silico Biology, 2008, v. 8, n. 2, p. 141, doi. 10.3233/isb-00353

By:

Jain, Preti;
Wadhwa, Puneet;
Aygun, Ramazan;
Podila, Gopi

Publication type:

Article

The Application of Abstract Topology to RAS-Related Signal Transduction Pathways.

Published in:

In Silico Biology, 2002, v. 2, n. 4, p. 453

By:

Cárdenas-García, Maura;
Lagunez Otero, Jaime;
Korneev, Nikolai A.

Publication type:

Article

The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.846215

By:

Petersen, Lara;
Stroh, Svenja;
Schöttelndreier, Dennis;
Grassl, Guntram A.;
Rottner, Klemens;
Brakebusch, Cord;
Fahrer, Jörg;
Genth, Harald

Publication type:

Article

The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.784856

By:

Papatheodorou, Panagiotis;
Kindig, Selina;
Badilla-Lobo, Adriana;
Fischer, Stephan;
Durgun, Ebru;
Thuraisingam, Tharani;
Witte, Alexander;
Song, Shuo;
Aktories, Klaus;
Chaves-Olarte, Esteban;
Rodríguez, César;
Barth, Holger

Publication type:

Article

Prognostic value of K- ras mutation status and subtypes in endoscopic ultrasound-guided fine-needle aspiration specimens from patients with unresectable pancreatic cancer.

Published in:

Journal of Gastroenterology, 2013, v. 48, n. 5, p. 640, doi. 10.1007/s00535-012-0664-2

By:

Ogura, Takeshi;
Yamao, Kenji;
Hara, Kazuo;
Mizuno, Nobumasa;
Hijioka, Susumu;
Imaoka, Hiroshi;
Sawaki, Akira;
Niwa, Yasumasa;
Tajika, Masahiro;
Kondo, Shinya;
Tanaka, Tsutomu;
Shimizu, Yasuhiro;
Bhatia, Vikram;
Higuchi, Kazuhide;
Hosoda, Waki;
Yatabe, Yasushi

Publication type:

Article

Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis.

Published in:

Oncogene, 2015, v. 34, n. 3, p. 346, doi. 10.1038/onc.2013.563

By:

Sales, K U;
Friis, S;
Konkel, J E;
Godiksen, S;
Hatakeyama, M;
Hansen, K K;
Rogatto, S R;
Szabo, R;
Vogel, L K;
Chen, W;
Gutkind, J S;
Bugge, T H

Publication type:

Article

The Ras-ERK pathway modulates cytoskeleton organization, cell motility and lung metastasis signature genes in MDA-MB-231 LM2.

Published in:

Oncogene, 2014, v. 33, n. 28, p. 3668, doi. 10.1038/onc.2013.341

By:

Choi, C;
Helfman, D M

Publication type:

Article

Review of dermatofibrosarcoma protuberans.

Published in:

Clinical & Experimental Dermatology, 2023, v. 48, n. 4, p. 297, doi. 10.1093/ced/llac111

By:

Lim, Su X;
Ramaiya, Arjun;
Levell, Nick J;
Venables, Zoe C

Publication type:

Article

Leveraging Topological Events in Tracking Graphs for Understanding Particle Diffusion.

Published in:

Computer Graphics Forum, 2021, v. 40, n. 3, p. 251, doi. 10.1111/cgf.14304

By:

McDonald, T.;
Shrestha, R.;
Yi, X.;
Bhatia, H.;
Chen, D.;
Goswami, D.;
Pascucci, V.;
Turbyville, T.;
Bremer, P.‐T.

Publication type:

Article

AtTRP1 encodes a novel TPR protein that interacts with the ethylene receptor ERS1 and modulates development in Arabidopsis.

Published in:

Journal of Experimental Botany, 2009, v. 60, n. 13, p. 3697, doi. 10.1093/jxb/erp209

By:

Zhefeng Lin;
Chin-Wen Ho;
Grierson, Don

Publication type:

Article

Phenotypic Expansion of Autosomal Dominant LZTR1 -Related Disorders with Special Emphasis on Adult-Onset Features.

Published in:

2024

By:

Uliana, Vera;
Ambrosini, Enrico;
Taiani, Antonietta;
Cesarini, Sofia;
Cannizzaro, Ilenia Rita;
Negrotti, Anna;
Serra, Walter;
Quintavalle, Gabriele;
Micale, Lucia;
Fusco, Carmela;
Castori, Marco;
Martorana, Davide;
Bortesi, Beatrice;
Belli, Laura;
Percesepe, Antonio;
Pisani, Francesco;
Barili, Valeria

Publication type:

Case Study

Unveiling the Mysteries of RAS Signaling: A Journey of Discovery and Breakthroughs.

Published in:

Genes, 2023, v. 14, n. 11, p. 1987, doi. 10.3390/genes14111987

By:

Castellano, Esther

Publication type:

Article

Drosophila as Model System to Study Ras-Mediated Oncogenesis: The Case of the Tensin Family of Proteins.

Published in:

Genes, 2023, v. 14, n. 7, p. 1502, doi. 10.3390/genes14071502

By:

Martínez-Abarca Millán, Ana;
Soler Beatty, Jennifer;
Valencia Expósito, Andrea;
Martín-Bermudo, María D.

Publication type:

Article

The Importance of Being PI3K in the RAS Signaling Network.

Published in:

Genes, 2021, v. 12, n. 7, p. 1094, doi. 10.3390/genes12071094

By:

Cuesta, Cristina;
Arévalo-Alameda, Cristina;
Castellano, Esther

Publication type:

Article

The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction.

Published in:

Genes, 2021, v. 13, n. 6, p. 819, doi. 10.3390/genes12060819

By:

Soriano, Olga;
Alcón-Pérez, Marta;
Vicente-Manzanares, Miguel;
Castellano, Esther

Publication type:

Article

The Role of Wild-Type RAS in Oncogenic RAS Transformation.

Published in:

Genes, 2021, v. 12, n. 5, p. 662, doi. 10.3390/genes12050662

By:

Sheffels, Erin;
Kortum, Robert L.;
Castellano-Sánchez, Esther

Publication type:

Article

A Premature Stop Codon in RAF1 Is the Priority Candidate Causative Mutation of the Inherited Chicken Wingless-2 Developmental Syndrome.

Published in:

Genes, 2019, v. 10, n. 5, p. 353, doi. 10.3390/genes10050353

By:

Youngworth, Ingrid;
Delany, Mary E.

Publication type:

Article

Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage.

Published in:

Virulence, 2021, v. 12, n. 1, p. 968, doi. 10.1080/21505594.2021.1899674

By:

Ashraf, Usama;
Ding, Zhen;
Deng, Shunzhou;
Ye, Jing;
Cao, Shengbo;
Chen, Zheng

Publication type:

Article

Targeting protein localization for anti-infective therapy.

Published in:

2017

By:

Alspaugh, J. Andrew

Publication type:

Science Experiment

Binding Mode Analysis of Bacillus subtilis Obg with Ribosomal Protein L13 through Computational Docking Study.

Published in:

Interdisciplinary Bio Central, 2009, n. 1, p. 1, doi. 10.4051/ibc.2009.1.0003

By:

Yuno Lee;
Woo Young Bang;
Songmi Kim;
Lazar, Prettina;
Jeong Dong Bahk;
Keun Woo Lee

Publication type:

Article

KRASG12C Inhibitors in Non-Small Cell Lung Cancer: A Review.

Published in:

OncoTargets & Therapy, 2024, v. 17, p. 683, doi. 10.2147/OTT.S473368

By:

Tang, Min;
Wu, Yijun;
Bai, Xiufeng;
Lu, You

Publication type:

Article

Aberrant MAPK Signaling Offers Therapeutic Potential for Treatment of Ovarian Carcinoma.

Published in:

OncoTargets & Therapy, 2022, v. 15, p. 1331, doi. 10.2147/OTT.S361512

By:

Colic, Eva;
Patel, Preya U;
Kent, Oliver A

Publication type:

Article