Works matching DE "DRUG resistance in cancer cells"

Results: 5000

Expression profile of the human IDO1 protein, a cancer drug target involved in tumoral immune resistance.

Published in:

OncoImmunology, 2015, v. 4, n. 5, p. 0, doi. 10.1080/2162402X.2014.1003012

By:

Vigneron, Nathalie;
van Baren, Nicolas;
Van den Eynde, Benoît J

Publication type:

Article

Understanding the influence of the tumor microenvironment on macrophage responses to CD40 agonists.

Published in:

OncoImmunology, 2014, v. 3, n. 2, p. N.PAG, doi. 10.4161/onci.27615

By:

Luheshi, Nadia;
Davies, Gareth;
Legg, James

Publication type:

Article

Targeting human CD27 with an agonist antibody stimulates T-cell activation and antitumor immunity.

Published in:

OncoImmunology, 2014, v. 3, n. 1, p. N.PAG, doi. 10.4161/onci.27255

By:

Thomas, Lawrence J;
He, Li-Zhen;
Marsh, Henry;
Keler, Tibor

Publication type:

Article

An immunotherapeutic intervention against tumor progression.

Published in:

OncoImmunology, 2014, v. 3, n. 1, p. N.PAG, doi. 10.4161/onci.27220

By:

Palena, Claudia;
Fernando, Romaine I;
Hamilton, Duane H

Publication type:

Article

Role of plasmacytoid dendritic cells in breast cancer bone dissemination.

Published in:

OncoImmunology, 2013, v. 2, n. 2, p. e22983-1, doi. 10.4161/onci.22983

By:

Sawant, Anandi;
Ponnazhagan, Selvarangan

Publication type:

Article

Phase I clinical trial combining imatinib mesylate and IL-2 in refractory cancer patients: IL-2 interferes with the pharmacokinetics of imatinib mesylate.

Published in:

OncoImmunology, 2013, v. 2, n. 2, p. e23079-1, doi. 10.4161/onci.23079

By:

Pautier, Patricia;
Locher, Clara;
Robert, Caroline;
Deroussent, Alain;
Flament, Caroline;
Le Cesne, Axel;
Rey, Annie;
Bahleda, Ratislav;
Ribrag, Vincent;
Soria, Jean-Charles;
Vassal, Gilles;
Eggermont, Alexander;
Zitvogel, Laurence;
Chaput, Nathalie;
Paci, Angelo

Publication type:

Article

Circulating microRNA-451 as a predictor of resistance to neoadjuvant chemotherapy in breast cancer.

Published in:

Cancer Biomarkers, 2016, v. 16, n. 3, p. 395, doi. 10.3233/CBM-160578

By:

Xi Gu;
Jin-Qi Xue;
Si-Jia Han;
Song-Ying Qian;
Wen-Hai Zhang

Publication type:

Article

Predictive factors to targeted treatment in gastrointestinal carcinomas.

Published in:

Cancer Biomarkers, 2014, v. 14, n. 3, p. 151, doi. 10.3233/CBM-130327

By:

Silvestris, Nicola;
Marech, Ilaria;
Brunetti, Anna Elisabetta;
Azzariti, Amalia;
Numico, Gianmauro;
Cicero, Giuseppe;
Delcuratolo, Sabina;
De Luca, Raffaele;
Burz, Claudia;
Lorusso, Vito

Publication type:

Article

The prognostic values of CA125, CA19.9, NSE, AND SCC for stage I NSCLC are limited.

Published in:

Cancer Biomarkers, 2012, v. 10, n. 3/4, p. 155, doi. 10.3233/CBM-2012-0246

By:

Ma, Shaohua;
Shen, Luyan;
Qian, Na;
Chen, Keneng

Publication type:

Article

Post-transcriptional regulation of O^{6}-methylguanine-DNA methyltransferase MGMT in glioblastomas.

Published in:

Cancer Biomarkers, 2012, v. 10, n. 3/4, p. 185, doi. 10.3233/CBM-2012-0245

By:

Ramakrishnan, Valya;
Kushwaha, Deepa;
Koay, Debbie C.;
Reddy, Hasini;
Mao, Ying;
Zhou, Liangfu;
Ng, Kimberly;
Zinn, Pascal;
Carter, Bob;
Chen, Clark C.

Publication type:

Article

Cancer stem cells and markers: New model of tumorigenesis with therapeutic implications.

Published in:

Cancer Biomarkers, 2011, v. 9, n. 1-6, p. 65

By:

Srivastava, Sudhir;
Grizzle, William E.;
Natarajan, Thanemozhi G.;
Ganesan, Natarajan;
FitzGerald, Kevin T.

Publication type:

Article

Hypoxia regulates glycolysis through the HIF-1α/BMAL1/ALDOC axis to reduce oxaliplatin sensitivity in colorectal cancer.

Published in:

Journal of Cancer, 2025, v. 16, n. 8, p. 2503, doi. 10.7150/jca.108582

By:

Jialing Ran;
Feifei Li;
Lei Zhan;
Yue Jin;
Qian Dong;
Xiaoyan Li;
XiaoXi Li;
Qian Fei;
Jingdong Zhang

Publication type:

Article

From predictive biomarker to therapeutic target: the dual role of SLFN11 in chemotherapy sensitivity.

Published in:

Cancer Chemotherapy & Pharmacology, 2025, v. 95, n. 1, p. 1, doi. 10.1007/s00280-025-04781-w

By:

Feng, Yue;
Li, Yingze;
Zhang, Zhenhao;
Dai, Yuxuan;
Gou, Xingchun;
Lao, Kejing;
Zhang, Running

Publication type:

Article

Cystathionine gamma‐lyase‐mediated hypoxia inducible factor 1‐alpha expression drives clear cell ovarian cancer progression.

Published in:

Journal of Pathology, 2025, v. 266, n. 3, p. 352, doi. 10.1002/path.6433

By:

EL‐Naggar, Amal M;
Li, Yuqin;
Turgu, Busra;
Ding, Yuchen;
Wei, Longyijie;
Chen, Shary Yuting;
Trigo‐Gonzalez, Genny;
Kalantari, Forouh;
Vallejos, Rodrigo;
Lynch, Branden;
Senz, Janine;
Lum, Amy;
Douglas, J Maxwell;
Salamanca, Clara;
Thornton, Shelby;
Qin, Yimei;
Parmar, Kiran;
Spencer, Sandra E;
Leung, Samuel;
Woo, Michelle M M

Publication type:

Article

Evaluating the multitargeted potency of Pixuvri against cell cycle regulation proteins in cervical cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1598883

By:

Alshehri, Mohammed Ali;
Alahdal, Hadil;
Aloqbi, Akram Ahmed;
Shakoori, Afnan Mohammed;
Sindi, Ghadir;
Bagadood, Rehab M.;
Alsaffar, Nida;
Alobaidy, Mohammad Ahmad;
Alrabiah, Noof Abdulrahman;
Khursheed, Md;
Tuwaijri, Abeer Al

Publication type:

Article

Advancing targeted therapy for colorectal cancer: harnessing ligand-directed enzyme prodrug therapy for highly specific interventions.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1570712

By:

Al-Jaber, Hend;
Biswas, Kabir H.;
Al-Mansoori, Layla

Publication type:

Article

靶向阻断 Sphk1促进奥沙利铂的抗结肠癌作用.

Published in:

Journal of Xi'an Jiaotong University (Medical Sciences), 2025, v. 46, n. 3, p. 435, doi. 10.7652/jdyxb202503008

By:

李政;
曹洁玮;
刘彬

Publication type:

Article

Targeted inhibition of Ninjurin2 promotes chemosensitivity in chemoresistant gastric cancer by suppressing cancer-initiating cells.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00792-0

By:

Shin, Hyo Shik;
Choi, Jae-Il;
Chung, Hye Won;
Park, Hee Jung;
Park, Hak;
Rim, John Hoon;
Lim, Jong-Baeck

Publication type:

Article

SPARC Promotes Aerobic Glycolysis and 5‐Fluorouracil Resistance in Colorectal Cancer Through the STAT3/HK2 Axis.

Published in:

Cancer Medicine, 2025, v. 14, n. 11, p. 1, doi. 10.1002/cam4.70972

By:

Xiang, Jingrong;
Zhang, Huan;
Shen, Kanger;
Feng, Jie;
Yang, Kexi;
Shi, Tongguo;
Xi, Qinhua

Publication type:

Article

Sex-determining region Y-Box 4 promotes the progression of advanced hepatocellular carcinoma and enhances regulatory T-cell infiltration and immune suppression.

Published in:

CytoJournal, 2025, v. 22, p. 1, doi. 10.25259/Cytojournal_27_2025

By:

Jing, Yingxia;
Wu, Yunlong

Publication type:

Article

The role and mechanism of fatty acid oxidation in cancer drug resistance.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02554-1

By:

Lei, Yun;
Cai, Shuang;
Zhang, Jia-Kui;
Ding, Si-Qi;
Zhang, Zhan-He;
Zhang, Chun-Dong;
Dai, Dong-Qiu;
Li, Yong-Shuang

Publication type:

Article

Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer.

Published in:

Cancer Nanotechnology (1868-6958), 2025, v. 16, n. 1, p. 1, doi. 10.1186/s12645-025-00329-y

By:

Li, Quanjiang;
Xie, Yufeng;
Zhang, Wanting;
Peng, Jun;
Deng, Zhujie;
Tian, Rui;
Kuang, Xiubin;
Xie, Bin;
Huang, Chen;
Zhao, Yu;
Yuan, Zhengqiang

Publication type:

Article

Single-cell transcriptomics identify a chemotherapy-resistance related cluster overexpressed CLIC3 in ovarian cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02882-9

By:

Li, Zhefeng;
Li, Jie;
Li, Yue;
Yi, Junjie;
Zhao, Xiaoting;
Yue, Wentao

Publication type:

Article

Glutamate activates the MAPK pathway by inhibiting LPAR1 expression and promotes anlotinib resistance in thyroid cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02853-0

By:

Liu, Bin;
Peng, Ying;
Su, Yanjun;
Diao, Chang;
Cha, Liansheng;
Cheng, Ruochuan

Publication type:

Article

Potential application of the wolly mouse in future research.

Published in:

2025

By:

Khanra, Supriya;
Datta, Aastha;
Charan, Shiv;
Kulkarni, Rutweek;
Prakash, Ajay;
Medhi, Bikash

Publication type:

Editorial

Enhancer RNAs profiling in colorectal cancer liver metastases reveals novel molecular subtypes with prognostic and therapeutic relevance.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02879-4

By:

Bu, Xiaoyun;
Wen, Dongsheng;
Zhou, Tiejun;
Xiao, Lei;
Zhang, Zhiqing;
Zhao, Xingshuai;
Hu, Yingbin

Publication type:

Article

Development of a Novel Biomarker Platform for Profiling Key Protein–Protein Interactions to Predict the Efficacy of BH3-Mimetic Drugs.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1852, doi. 10.3390/cancers17111852

By:

Kinloch, Andrew J.;
Rahman, Faiyaz;
Karakas, Bahriye;
Shahid, Muhammad;
Lim, Bora;
Bouley, Stephanie J.;
Walker, James A.;
Lee, Erinna F.;
Fairlie, Walter D.;
Kelly, Kevin R.;
Cardone, Michael H.

Publication type:

Article

Phase Ia/Ib Study of Afatinib with Capecitabine in Patients with Refractory Solid Tumors and Pancreaticobiliary Cancers.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1830, doi. 10.3390/cancers17111830

By:

King, Gentry G.;
Baker, Kelsey K.;
Coveler, Andrew L.;
Harris, William P.;
Cohen, Stacey A.;
Shankaran, Veena;
Zhen, David B.;
Safyan, Rachael A.;
Lee, Hannah H.;
Alidina, Annie;
Hensel, Jeniece;
Hibbert, Reina;
Durm, Greg A.;
LaFary, Yvonne C.;
Younger, Anne;
Kugel, Sita;
Collisson, Eric;
Konnick, Eric Q.;
Redman, Mary W.;
Schneider, Bryan P.

Publication type:

Article

Systemic Therapeutic Options in Radioiodine-Refractory Differentiated Thyroid Cancer: Current Indications and Optimal Timing.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1800, doi. 10.3390/cancers17111800

By:

Díaz Vico, Tamara;
Martínez-Amores Martínez, Brezo;
Mihic Góngora, Luka;
Jiménez-Fonseca, Paula;
Peinado Martín, Paloma;
Grao Torrente, Irene;
García Muñoz-Nájar, Alejandro;
Durán-Poveda, Manuel

Publication type:

Article

The Roles of STAT3 and STAT5 in Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1781, doi. 10.3390/cancers17111781

By:

Temple, Alexandra E.;
Walker, Sarah R.

Publication type:

Article

Docetaxel Administration via Novel Hierarchical Nanoparticle Reduces Proinflammatory Cytokine Levels in Prostate Cancer Cells.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1758, doi. 10.3390/cancers17111758

By:

Aalinkeel, Ravikumar;
Sharma, Satish;
Mahajan, Supriya D.;
Prasad, Paras N.;
Schwartz, Stanley A.

Publication type:

Article

Advances in Isorhamnetin Treatment of Malignant Tumors: Mechanisms and Applications.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1853, doi. 10.3390/nu17111853

By:

Mei, Chen;
Liu, Ying;
Lyu, Xueze;
Jiang, Zhaoling;
Liu, Zhenyi;
Zhi, Yan;
Xu, Xiaolong;
Wang, Hongjun

Publication type:

Article

Glucosylceramide Synthase, a Key Enzyme in Sphingolipid Metabolism, Regulates Expression of Genes Accounting for Cancer Drug Resistance.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5112, doi. 10.3390/ijms26115112

By:

Mostaq, Md Saqline;
Kang, Lin;
Patwardhan, Gauri A.;
Zhao, Yunfeng;
Shi, Runhua;
Liu, Yong-Yu

Publication type:

Article

AKT1 and CTNNB1 mutations as drivers of paclitaxel resistance in breast cancer cells.

Published in:

Oncology Letters, 2025, v. 30, n. 1, p. N.PAG, doi. 10.3892/ol.2025.15070

By:

Altiparmak-Ulbegi, Gulsum;
Hasbal-Celikok, Gozde;
Aksoy-Sagirli, Pinar

Publication type:

Article

Chlorogenic Acid Enhances Beta‐Lapachone‐Induced Cell Death by Suppressing Autophagy in NQO1‐Positive Cancer Cells.

Published in:

Cell Biology International, 2025, v. 49, n. 5, p. 555, doi. 10.1002/cbin.70006

By:

Zada, Sahib;
Bahar, Md Entaz;
Kim, Wanil;
Kim, Deok Ryong

Publication type:

Article

Automatic target-seeking nanoparticle inhibiting orthotopic drug-resistant colon cancer and liver metastases via regulating cancer cell adhesion and proliferation.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03422-x

By:

Bai, Shaobo;
Sun, Yang;
Liu, Miao;
Cheng, Ying;
Ji, Qifeng;
Zhang, Bangle;
Yang, Zhifu;
Zhou, Siyuan;
Liu, Daozhou

Publication type:

Article

Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00788-w

By:

Zhang, Li;
Yang, Yang;
Li, Yanchu;
Wang, Chenyu;
Bian, Chenbin;
Wang, Hongbin;
Wang, Feng

Publication type:

Article

Hydrogen Sulfide Expression May Affect Ovarian Cancer Progression and Drug Resistance.

Published in:

International Journal of Women's Health, 2025, v. 17, p. 1533, doi. 10.2147/IJWH.S515836

By:

Zhu, Qiong;
Liu, Yi;
Zhou, Juan;
Tan, Miduo;
Xue, Yaxin;
Tao, Yin

Publication type:

Article

Immunotherapies versus small-molecule therapies of cancers with RAS oncogene mutations.

Published in:

Polish Journal of Allergology / Alergologia Polska, 2025, v. 12, n. 2, p. 111, doi. 10.5114/pja.2025.148075

By:

Rieske, Piotr

Publication type:

Article

Combination strategies of gut microbiota in cancer therapy through metabolic reprogramming and immune remodeling.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02275-z

By:

Wang, Lixuan;
Jiang, Weibo;
Yang, Manshi;
Danzeng, Quezhu;
Liu, Shiyu;
Cui, Mengying

Publication type:

Article

Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab-resistant HER2-positive breast cancer.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103953

By:

Yijia Hua;
Ningjun Duan;
Chunxiao Sun;
Fan Yang;
Min Tian;
Yanting Sun;
Shuhan Zhao;
Jue Gong;
Qian Liu;
Xiang Huang;
Yan Liang;
Ziyi Fu;
Wei Li;
Yongmei Yin

Publication type:

Article

EZH2 promotes chemoresistance in colorectal cancer by inhibiting autophagy through NRP1 suppression.

Published in:

Biochemical Journal, 2025, v. 482, n. 10, p. 569, doi. 10.1042/bcj20240607

By:

Hong Deng;
Qin Xu;
Qiang Zhang;
Chunfeng Liu;
Lei Ren

Publication type:

Article

Research progress of galectins in glioma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02318-4

By:

Feng, Xin-Li;
Su, Gang;
Wu, Qiong-Hui;
Jia, Qi;
Zhang, Zhen-Chang

Publication type:

Article

Mechanism and application of lactylation in cancers.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01415-9

By:

Wang, Jiewen;
Peng, Mingjing;
Oyang, Linda;
Shen, Mengzhou;
Li, Shizhen;
Jiang, Xianjie;
Ren, Zongyao;
Peng, Qiu;
Xu, Xuemeng;
Tan, Shiming;
Xia, Longzheng;
Yang, Wenjuan;
Li, Haofan;
Wu, Nayiyuan;
Tang, Yanyan;
Lin, Jinguan;
Liao, Qianjin;
Han, Yaqian;
Zhou, Yujuan

Publication type:

Article

间质性肺疾病急性加重危险因素及治疗进展.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 5, p. 1219, doi. 10.3969/j.issn.1009-5519.2025.05.035

By:

罗子悦;
江宇

Publication type:

Article

IGF2BP3在肝癌中的研究进展.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 5, p. 1214, doi. 10.3969/j.issn.1009-5519.2025.05.034

By:

杨宛林;
叶宇璐;
宁登冲;
叶霞;
蓝金艳;
易廷庄

Publication type:

Article

Novel insights into the N 6-methyladenosine modification on circRNA in cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1554888

By:

Xu, Qingling;
Jia, Yi;
Liu, Ying;
Wu, Bing;
Wang, Jianxun;
Ao, Xiang;
Ding, Wei

Publication type:

Article

Comprehensive analysis of breast cancer oxidative stress related gene signature: a combination of bulk and single-cell RNA sequencing analysis.

Published in:

Mammalian Genome, 2025, v. 36, n. 2, p. 692, doi. 10.1007/s00335-025-10130-2

By:

Shao, Yuheng;
Zhang, Yumeng;
Chen, Jie;
Yang, Liang;
Wu, Meihong;
Fan, Zhiyuan;
Zhuang, Zhigang

Publication type:

Article

Inhibition of TPI1 Sensitizes Cisplatin-Resistant Oral Cancer to Ferroptosis.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1225, doi. 10.3390/biomedicines13051225

By:

Wang, Dandan;
Zheng, Huimin;
Chen, Yumin;
Hao, Jialin;
Zhou, Yuan;
Li, Nan

Publication type:

Article

Targeting Drug Resistance in Cancer: Dimethoxycurcumin as a Functional Antioxidant Targeting ABCC3.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 599, doi. 10.3390/antiox14050599

By:

Nelen, Jochem;
Naponelli, Valeria;
Villalgordo-Soto, José Manuel;
Falasca, Marco;
Pérez-Sánchez, Horacio

Publication type:

Article