Works matching DE "METABOLIC clearance rate"

Results: 256

Application of an alcohol clamp paradigm to examine inhibitory control, subjective responses, and acute tolerance in late adolescence.

Published in:

2015

By:

Hendershot, Christian S.;
Wardell, Jeffrey D.;
Strang, Nicole M.;
Markovich, Mike S. D.;
Claus, Eric D.;
Ramchandani, Vijay A.

Publication type:

Journal Article

Cocaine transiently impairs maternal behavior in the rat.

Published in:

1996

By:

Vernotica, E. M.;
Lisciotto, C. A.;
Rosenblatt, J. S.;
Morrell, J. I.

Publication type:

Journal Article

Effects of estradiol benzoate and MER-25 on ethanol consumption in the ovariectomized rat.

Published in:

1982

By:

Sandberg, David;
Stewart, Jane

Publication type:

Journal Article

Population pharmacokinetic analyses of methotrexate in pediatric patients: a systematic review.

Published in:

European Journal of Clinical Pharmacology, 2024, v. 80, n. 7, p. 965, doi. 10.1007/s00228-024-03665-x

By:

Cheng, Yu;
Zhang, Yujia;
Zhang, Ying;
Liu, Maobai;
Zhao, Limei

Publication type:

Article

Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review.

Published in:

European Journal of Clinical Pharmacology, 2024, v. 80, n. 1, p. 11, doi. 10.1007/s00228-023-03579-0

By:

Yang, Yunyun;
Liu, Zhengyue;
Chen, Jingxia;
Wang, Xuebin;
Jiao, Zheng;
Wang, Zhuo

Publication type:

Article

Role of ADME gene polymorphisms on imatinib disposition: results from a population pharmacokinetic study in chronic myeloid leukaemia.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 8, p. 1321, doi. 10.1007/s00228-022-03345-8

By:

Shriyan, Bharati;
Mehta, Parsshava;
Patil, Anand;
Jadhav, Shraddha;
Kumar, Sharath;
Puri, Apeksha S.;
Govalkar, Ravina;
Krishnamurthy, Manjunath Nookala;
Punatar, Sachin;
Gokarn, Anant;
Khattry, Navin;
Gota, Vikram

Publication type:

Article

Delayed crises following benzodiazepine withdrawal: deficient adaptive mechanisms or simple pharmacokinetics? Detoxification assisted by serum-benzodiazepine elimination tracking.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 1, p. 101, doi. 10.1007/s00228-021-03205-x

By:

Basińska-Szafrańska, Anna

Publication type:

Article

Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies.

Published in:

European Journal of Clinical Pharmacology, 2021, v. 77, n. 5, p. 727, doi. 10.1007/s00228-020-03042-4

By:

Wasmann, Roeland E.;
Svensson, Elin M.;
Schalkwijk, Stein J.;
Brüggemann, Roger J.;
ter Heine, Rob

Publication type:

Article

Pharmacokinetic variability of phenobarbital: a systematic review of population pharmacokinetic analysis.

Published in:

European Journal of Clinical Pharmacology, 2021, v. 77, n. 3, p. 291, doi. 10.1007/s00228-020-03011-x

By:

Methaneethorn, Janthima;
Leelakanok, Nattawut

Publication type:

Article

Uncovering the potential mechanism of Xue Fu Zhu Yu Decoction in the treatment of intracerebral hemorrhage.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03577-2

By:

Dao-jin Xue;
Zheng Zhen;
Ke-xin Wang;
Jia-lin Zhao;
Yao Gao;
Yu-peng Chen;
You-bi Shen;
Zi-zhuang Peng;
Dao-gang Guan;
Tao Huang

Publication type:

Article

Four-Compartment Diffusion Model of Cortisol Disposition: Comparison With 3 Alternative Models in Current Clinical Use.

Published in:

Journal of the Endocrine Society, 2023, v. 7, n. 2, p. 1, doi. 10.1210/jendso/bvac173

By:

Dorin, Richard I;
Urban, Frank K;
Perogamvros, Ilias;
Qualls, Clifford R

Publication type:

Article

Recent developments in predicting CYP-independent metabolism.

Published in:

Drug Metabolism Reviews, 2021, v. 53, n. 2, p. 188, doi. 10.1080/03602532.2021.1923728

By:

Dhuria, Nikhilesh V.;
Haro, Bianka;
Kapadia, Amit;
Lobo, Khadjia A.;
Matusow, Bernice;
Schleiff, Mary A.;
Tantoy, Christina;
Sodhi, Jasleen K.

Publication type:

Article

Cytochrome P450 structure–function: insights from molecular dynamics simulations.

Published in:

Drug Metabolism Reviews, 2016, v. 48, n. 3, p. 434, doi. 10.1080/03602532.2016.1178771

By:

Nair, Pramod C.;
McKinnon, Ross A.;
Miners, John O.

Publication type:

Article

Dynamic FDG-PET demonstration of functional brain abnormalities.

Published in:

Annals of Clinical & Translational Neurology, 2022, v. 9, n. 9, p. 1487, doi. 10.1002/acn3.51546

By:

Quigg, Mark;
Kundu, Bijoy

Publication type:

Article

Impact of body size on first‐line Helicobacter pylori eradication success using vonoprazan and amoxicillin dual therapy.

Published in:

Helicobacter, 2021, v. 26, n. 2, p. 1, doi. 10.1111/hel.12788

By:

Eto, Hiroyuki;
Suzuki, Sho;
Kusano, Chika;
Ikehara, Hisatomo;
Ichijima, Ryoji;
Ito, Hirotaka;
Kawabe, Koichi;
Kawamura, Masashi;
Yoda, Yoshioki;
Nakahara, Moriyasu;
Gotoda, Takuji

Publication type:

Article

NSAID–Gut Microbiota Interactions.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01153

By:

Maseda, Damian;
Ricciotti, Emanuela

Publication type:

Article

Optimal 2-[F]fluoro-2-deoxy- d-galactose PET/CT protocol for detection of hepatocellular carcinoma.

Published in:

EJNMMI Research, 2016, v. 6, n. 1, p. 1, doi. 10.1186/s13550-016-0206-7

By:

Horsager, Jacob;
Bak-Fredslund, Kirstine;
Larsen, Lars;
Villadsen, Gerda;
Bogsrud, Trond;
Sørensen, Michael

Publication type:

Article

Influence of CYP2D6, CYP2C19 and CYP3A5 polymorphisms on plasma levels of tamoxifen metabolites in Algerian women with ER<sup>+</sup> breast cancer.

Published in:

Egyptian Journal of Medical Human Genetics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s43042-022-00332-7

By:

Boucenna, Amira;
Boudaoud, Khadidja;
Hireche, Ahmed;
Rezgoune, Mohamed Larbi;
Abadi, Noureddine;
Filali, Taha;
Satta, Dalila

Publication type:

Article

The Correlation of Two Different Real-Time PCR Devices for the Analysis of CYP2C19 Pharmacogenetic Results.

Published in:

Scientia Pharmaceutica, 2023, v. 91, n. 4, p. 51, doi. 10.3390/scipharm91040051

By:

Alonso Llorente, Alba;
Salgado Garrido, Josefa;
Teijido Hermida, Oscar;
González Andrade, Fabricio;
Valiente Martín, Alberto;
Fanlo Villacampa, Ana;
Vicente Romero, Jorge

Publication type:

Article

Development and Verification of a Japanese Pediatric Physiologically Based Pharmacokinetic Model with Emphasis on Drugs Eliminated by Cytochrome P450 or Renal Excretion.

Published in:

Journal of Clinical Pharmacology, 2023, v. 63, n. 10, p. 1156, doi. 10.1002/jcph.2317

By:

Johnson, Trevor N.;
Abduljalil, Khaled;
Pan, Xian;
Emoto, Chie

Publication type:

Article

Total, Unbound, Renal, and Hepatic Clearances of Raltegravir and the Formation and Elimination Clearances of Raltegravir Glucuronide in Pregnant Women.

Published in:

Journal of Clinical Pharmacology, 2023, v. 63, n. 9, p. 1053, doi. 10.1002/jcph.2287

By:

Moreira, Fernanda de Lima;
Paz, Tiago Antunes;
Melli, Patrícia Pereira dos Santos;
Thomaz, Matheus de Lucca;
Marques, Maria Paula;
Rocha, Adriana;
Duarte, Geraldo;
Lanchote, Vera Lucia

Publication type:

Article

Use of Physiologically Based Pharmacokinetic Modeling for Hepatically Cleared Drugs in Pregnancy: Regulatory Perspective.

Published in:

Journal of Clinical Pharmacology, 2023, v. 63, p. S62, doi. 10.1002/jcph.2266

By:

Coppola, Paola;
Kerwash, Essam;
Cole, Susan

Publication type:

Article

Population Pharmacokinetics of Tacrolimus in Pediatric Patients With Umbilical Cord Blood Transplant.

Published in:

Journal of Clinical Pharmacology, 2023, v. 63, n. 3, p. 298, doi. 10.1002/jcph.2162

By:

Zuo, Meiling;
Shang, Yue;
Guo, Ye;
Sun, Yuxuan;
Xu, Gaoqi;
Chen, Jingtao;
Zhu, Liqin

Publication type:

Article

Bridging the Gap With Clinical Pharmacology in Innovative Rare Disease Treatment Modalities: Targeting DNA to RNA to Protein.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, p. S95, doi. 10.1002/jcph.2172

By:

Lee, Lucy;
Gollen, Rakesh;
Fathallah, Anas M.;
Gao, Lan;
Patil, Shivakumar

Publication type:

Article

Population Pharmacokinetic Modeling of Lenvatinib in Chinese Patients With Advanced Hepatocellular Carcinoma Using Real‐World Data.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 12, p. 1507, doi. 10.1002/jcph.2103

By:

Hu, Yingying;
Chen, Ruijia;
Ye, Zhenjie;
Wei, Fuqun;
Lin, Kecan;
Liu, Jingfeng;
Zeng, Yongyi

Publication type:

Article

Drug Disposition in Subjects With Obesity: The Research Work of Darrell R. Abernethy.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 11, p. 1350, doi. 10.1002/jcph.2093

By:

Greenblatt, David J.;
Bruno, Christopher D.;
Harmatz, Jerold S.;
Zhang, Qingchen;
Chow, Christina R.

Publication type:

Article

Population Pharmacokinetics of Hydroxychloroquine Sulfate in Healthcare Workers, Given for Prophylaxis Against Coronavirus Disease 2019 (COVID‐19) in India.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 11, p. 1403, doi. 10.1002/jcph.2092

By:

Raj, Jeffrey Pradeep;
Gogtay, Nithya Jaideep;
Pandey, Avaneesh;
Kakkar, Ashish Kumar;
Shafiq, Nusrat;
Mekala, Padmaja;
Pingali, Usharani;
Raju, Arun Prasath;
Mallayasamy, Surulivelrajan;
Kshirsagar, Nilima Arun

Publication type:

Article

Predictive Value of C‐Reactive Protein and Albumin for Temporal Within‐Individual Pharmacokinetic Variability of Voriconazole in Pediatric Patients Undergoing Hematopoietic Cell Transplantation.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 7, p. 855, doi. 10.1002/jcph.2024

By:

Takahashi, Takuto;
Jaber, Mutaz M.;
Smith, Angela R.;
Jacobson, Pamala A.;
Fisher, James;
Kirstein, Mark N.

Publication type:

Article

Population Pharmacokinetic Analysis and Dosing Optimization of Sirolimus in Children With Tuberous Sclerosis Complex.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 8, p. 948, doi. 10.1002/jcph.2033

By:

Li, SiChan;
Zhan, Min;
Wu, SanLan;
Liao, JianXiang;
Xu, Hua;
Sun, Dan;
Zhao, Xia;
Wang, Yang

Publication type:

Article

Population Pharmacokinetics and Pharmacodynamics of Burosumab in Adult and Pediatric Patients With X‐linked Hypophosphatemia.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 1, p. 87, doi. 10.1002/jcph.1950

By:

Lee, Sun Ku;
Gosselin, Nathalie H.;
Taylor, Julie;
Roberts, Mary Scott;
McKeever, Kathleen;
Shi, Jack

Publication type:

Article

Concordance of Exposure Changes Because of Renal Impairment Between Results of Dedicated Renal Impairment Studies and Population Pharmacokinetic Predictions.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 10, p. 1324, doi. 10.1002/jcph.1907

By:

Ahmed, Mariam A.;
Kalaria, Shamir N.;
Younis, Islam R.

Publication type:

Article

Population Pharmacokinetic Modeling and Simulations of Imipenem in Burn Patients With and Without Continuous Venovenous Hemofiltration in the Military Health System.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 9, p. 1182, doi. 10.1002/jcph.1865

By:

Por, Elaine D.;
Akers, Kevin S.;
Chung, Kevin K.;
Livezey, Jeffrey R.;
Selig, Daniel J.

Publication type:

Article

Spreadsheet‐Based Minimal Physiological Models for the Prediction of Clearance of Therapeutic Proteins in Pediatric Patients.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, p. S108, doi. 10.1002/jcph.1846

By:

Mahmood, Iftekhar;
Tegenge, Million A.

Publication type:

Article

Application of Individualized PBPK Modeling of Rate Data to Evaluate the Effect of Hemodialysis on Nonrenal Clearance Pathways.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 6, p. 769, doi. 10.1002/jcph.1818

By:

Franchetti, Yoko;
Nolin, Thomas D.

Publication type:

Article

Increased Induction Infliximab Clearance Predicts Early Antidrug Antibody Detection.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 2, p. 224, doi. 10.1002/jcph.1732

By:

Eser, Alexander;
Reinisch, Walter;
Schreiber, Stefan;
Ahmad, Tariq;
Boulos, Suliman;
Mould, Diane R.

Publication type:

Article

A critical approach on pharmacokinetics, pharmacodynamics, dose optimisation and withdrawal times of oxytetracycline in aquaculture.

Published in:

Reviews in Aquaculture, 2015, v. 7, n. 2, p. 77, doi. 10.1111/raq.12055

By:

Rigos, George;
Smith, Peter

Publication type:

Article

A follow-up history of young man with apparent cortisone reductase deficiency (ACRD) - several years after diagnosis.

Published in:

Pediatric Endocrinology, Diabetes & Metabolism, 2017, v. 23, n. 1, p. 42, doi. 10.18544/PEDM-23.01.0073

By:

Zajkowska, Adrianna;
Rydzewska, Marta;
Wojtkielewicz, Katarzyna;
Pomaski, Janusz;
Romer, Tomasz;
Bossowski, Artur

Publication type:

Article

Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolism

Published in:

Xenobiotica, 2020, v. 50, n. 11, p. 1370, doi. 10.1080/00498254.2020.1769229

By:

Sanoh, Seigo;
Naritomi, Yoichi;
Kitamura, Satoshi;
Shinagawa, Akihiko;
Kakuni, Masakazu;
Tateno, Chise;
Ohta, Shigeru

Publication type:

Article

FEK self‐assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening.

Published in:

Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2022, v. 110, n. 9, p. 2015, doi. 10.1002/jbm.b.35056

By:

He, Ting;
Qiao, Shida;
Ma, Chen;
Peng, Zhaoliang;
Wu, Zhitao;
Ma, Chenhui;
Han, Li;
Deng, Qiangqiang;
Zhang, Tianwei;
Zhu, Yishen;
Pan, Guoyu

Publication type:

Article

Expression of CYP2B6 Enzyme in Human Liver Tissue of HIV and HCV Patients.

Published in:

Medicina (1010660X), 2023, v. 59, n. 7, p. 1207, doi. 10.3390/medicina59071207

By:

Obradovic, Bozana;
Roberts, Owain;
Owen, Andrew;
Milosevic, Ivana;
Milic, Natasa;
Ranin, Jovan;
Dragovic, Gordana

Publication type:

Article

Food interactions with tyrosine kinase inhibitors used to treat advanced renal cell carcinoma.

Published in:

Contemporary Oncology / Współczesna Onkologia, 2025, v. 29, n. 1, p. 1, doi. 10.5114/wo.2025.148229

By:

Sałek-Zań, Agata;
Püsküllüoğlu, Mirosława;
Syrek-Kaplita, Karolina;
Banaś, Tomasz

Publication type:

Article

Need for alternatives to animals in experimentation: An Indian perspective.

Published in:

Indian Journal of Medical Research, 2019, v. 149, n. 5, p. 584, doi. 10.4103/ijmr.IJMR_2047_17

By:

Swaminathan, Soumya;
Kumar, Vijay;
Kaul, Rajni

Publication type:

Article

High tacrolimus clearance – a risk factor for development of interstitial fibrosis and tubular atrophy in the transplanted kidney: a retrospective single‐center cohort study.

Published in:

Transplant International, 2019, v. 32, n. 3, p. 257, doi. 10.1111/tri.13356

By:

Egeland, Erlend Johannessen;
Reisæter, Anna Varberg;
Robertsen, Ida;
Midtvedt, Karsten;
Strøm, Erik Heyerdahl;
Holdaas, Hallvard;
Hartmann, Anders;
Åsberg, Anders

Publication type:

Article

A spotlight on underlying the mechanism of AMPK in diabetes complications.

Published in:

Inflammation Research, 2021, v. 70, n. 9, p. 939, doi. 10.1007/s00011-021-01488-5

By:

Behl, Tapan;
Gupta, Amit;
Sehgal, Aayush;
Sharma, Sanchay;
Singh, Sukhbir;
Sharma, Neelam;
Diaconu, Camelia Cristina;
Rahdar, Abbas;
Hafeez, Abdul;
Bhatia, Saurabh;
Al-Harrasi, Ahmed;
Bungau, Simona

Publication type:

Article

Clinical and Therapeutic Implications of BCAAs Metabolism during Chronic Liver Disease in Humans: Crosstalk between Skeletal Muscle and Liver.

Published in:

Muscles (2813-0413), 2024, v. 3, n. 1, p. 71, doi. 10.3390/muscles3010008

By:

Trillos-Almanza, Maria Camila;
Martinez-Aguilar, Magnolia;
Arroyave-Ospina, Johanna C.;
van Vilsteren, Frederike;
Blokzijl, Hans;
Moshage, Han

Publication type:

Article

Liver function after transplantation in the assessment of the coagulation system and the concept of antithrombotic therapy.

Published in:

Gastroenterology Review / Przegląd Gastroenterologiczny, 2020, v. 15, n. 1, p. 48, doi. 10.5114/pg.2020.93631

By:

Lukaszewski, Marceli;
Jakubaszko, Jacek;
Bielicki, Grzegorz;
Koscielska-Kasprzak, Katarzyna;
Kosiorowska, Kinga

Publication type:

Article

No Sequestration of Commonly Used Anti-Infectives in the Extracorporeal Membrane Oxygenation (ECMO) Circuit—An Ex Vivo Study.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 4, p. 373, doi. 10.3390/antibiotics13040373

By:

Booke, Hendrik;
Friedrichson, Benjamin;
Draheim, Lena;
von Groote, Thilo Caspar;
Frey, Otto;
Röhr, Anka;
Zacharowski, Kai;
Adam, Elisabeth Hannah

Publication type:

Article

Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A.

Published in:

Translational & Clinical Pharmacology, 2020, v. 28, n. 2, p. 73, doi. 10.12793/tcp.2020.28.e10

By:

Yujin Lee;
Woori Chae;
Seonghae Yoon;
Jae-Yong Chung;
Joo-Youn Cho

Publication type:

Article

Perioperative Temperature Management.

Published in:

Journal of Anesthesia / Anestezi Dergisi (JARSS), 2023, v. 31, p. 58

By:

Kuzmanovska, Biljana

Publication type:

Article

Physiologically‐based pharmacokinetic modeling for investigating the effect of simeprevir on concomitant drugs and an endogenous biomarker of OATP1B.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 10, p. 1461, doi. 10.1002/psp4.13023

By:

Nakayama, Shinji;
Toshimoto, Kota;
Yamazaki, Shinji;
Snoeys, Jan;
Sugiyama, Yuichi

Publication type:

Article