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Knockout of the Carbohydrate Responsive Element Binding Protein Enhances Proliferation and Tumorigenesis in Renal Tubules of Mice.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 21, p. 11438, doi. 10.3390/ijms252111438
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- Publication type:
- Article
Autopsy findings after long-term treatment of COVID-19 patients with microbiological correlation.
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- Virchows Archiv: European Journal of Pathology, 2021, v. 479, n. 1, p. 97, doi. 10.1007/s00428-020-03014-0
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- Publication type:
- Article
Nuclear ErbB2 expression in hepatocytes in liver disease.
- Published in:
- Virchows Archiv: European Journal of Pathology, 2021, v. 478, n. 2, p. 309, doi. 10.1007/s00428-020-02871-z
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- Publication type:
- Article
Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities.
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- Journal of Personalized Medicine, 2022, v. 12, n. 8, p. 1270, doi. 10.3390/jpm12081270
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- Publication type:
- Article
eIF4A1 Is a Prognostic Marker and Actionable Target in Human Hepatocellular Carcinoma.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2055, doi. 10.3390/ijms24032055
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- Publication type:
- Article
Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8467, doi. 10.3390/ijms21228467
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- Publication type:
- Article
The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models.
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- International Journal of Molecular Sciences, 2016, v. 17, n. 10, p. 1618, doi. 10.3390/ijms17101618
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- Publication type:
- Article
Cholangiocarcinomas can originate from hepatocytes in mice.
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- Journal of Clinical Investigation, 2012, v. 122, n. 8, p. 2911, doi. 10.1172/JCI63212
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- Publication type:
- Article
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma.
- Published in:
- 2007
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- Publication type:
- journal article
Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development.
- Published in:
- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02286-9
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- Publication type:
- Article
Genetic Predisposition to Hepatocellular Carcinoma.
- Published in:
- Metabolites (2218-1989), 2023, v. 13, n. 1, p. 35, doi. 10.3390/metabo13010035
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- Publication type:
- Article
Identification and In-Depth Analysis of the Novel FGFR2-NDC80 Fusion in a Cholangiocarcinoma Patient: Implication for Therapy.
- Published in:
- Current Oncology, 2021, v. 28, n. 2, p. 1161, doi. 10.3390/curroncol28020112
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- Publication type:
- Article
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.
- Published in:
- Nature Medicine, 2006, v. 12, n. 4, p. 410, doi. 10.1038/nm1377
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- Publication type:
- Article
Application of comparative functional genomics to identify best-fit mouse models to study human cancer.
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- Nature Genetics, 2004, v. 36, n. 12, p. 1306, doi. 10.1038/ng1481
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- Publication type:
- Article
Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
- Published in:
- Scientific Reports, 2016, p. 20484, doi. 10.1038/srep20484
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- Publication type:
- Article
SCD1 Expression Is Dispensable for Hepatocarcinogenesis Induced by AKT and Ras Oncogenes in Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075104
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- Publication type:
- Article
Bmi1 Is Required for Hepatic Progenitor Cell Expansion and Liver Tumor Development.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046472
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- Publication type:
- Article
Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice.
- Published in:
- Oncogene, 2005, v. 24, n. 54, p. 8003, doi. 10.1038/sj.onc.1208940
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- Publication type:
- Article
Early Subcellular Hepatocellular Alterations in Mice Post Hydrodynamic Transfection: An Explorative Study.
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- Cancers, 2023, v. 15, n. 2, p. 328, doi. 10.3390/cancers15020328
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- Publication type:
- Article
Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC.
- Published in:
- Cancers, 2021, v. 13, n. 2, p. 199, doi. 10.3390/cancers13020199
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- Publication type:
- Article
Genetic Mouse Models as In Vivo Tools for Cholangiocarcinoma Research.
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- Cancers, 2019, v. 11, n. 12, p. 1868, doi. 10.3390/cancers11121868
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- Publication type:
- Article
Experimental Models to Define the Genetic Predisposition to Liver Cancer.
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- Cancers, 2019, v. 11, n. 10, p. 1450, doi. 10.3390/cancers11101450
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- Publication type:
- Article
Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma.
- Published in:
- Cancers, 2019, v. 11, n. 7, p. 930, doi. 10.3390/cancers11070930
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- Publication type:
- Article
NORE1A Regulates MDM2 Via β-TrCP.
- Published in:
- Cancers, 2016, v. 8, n. 4, p. 39, doi. 10.3390/cancers8040039
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- Publication type:
- Article
RASSF1A independence and early galectin‐1 upregulation in PIK3CA‐induced hepatocarcinogenesis: new therapeutic venues.
- Published in:
- Molecular Oncology, 2022, v. 16, n. 5, p. 1091, doi. 10.1002/1878-0261.13135
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- Publication type:
- Article
Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis.
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- BMC Cancer, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12885-023-11577-9
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- Publication type:
- Article
Cholangiocarcinoma: State‐of‐the‐art knowledge and challenges.
- Published in:
- Liver International, 2019, v. 39, p. 5, doi. 10.1111/liv.14101
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- Publication type:
- Article
Experimental models to unravel the molecular pathogenesis, cell of origin and stem cell properties of cholangiocarcinoma.
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- Liver International, 2019, v. 39, p. 79, doi. 10.1111/liv.14094
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- Publication type:
- Article
The complex role of bone morphogenetic protein 9 in liver damage and regeneration: New evidence from in vivo and in vitro studies.
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- Liver International, 2018, v. 38, n. 9, p. 1547, doi. 10.1111/liv.13925
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- Publication type:
- Article
Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells.
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- Liver International, 2017, v. 37, n. 1, p. 80, doi. 10.1111/liv.13183
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- Publication type:
- Article
Activated mutant forms of PIK3 CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/ mTORC1 cascade.
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- Liver International, 2016, v. 36, n. 8, p. 1176, doi. 10.1111/liv.13055
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- Publication type:
- Article
Focal adhesion kinase activation limits efficacy of Dasatinib in c‐Myc driven hepatocellular carcinoma.
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- Cancer Medicine, 2018, v. 7, n. 12, p. 6170, doi. 10.1002/cam4.1777
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- Publication type:
- Article
Cabozantinib for HCC Treatment, From Clinical Back to Experimental Models.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.756672
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- Publication type:
- Article
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.
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- Carcinogenesis, 2008, v. 29, n. 8, p. 1639, doi. 10.1093/carcin/bgn155
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- Publication type:
- Article
Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/{beta}-catenin pathway and progression of early lesions in the rat.
- Published in:
- Carcinogenesis, 2007, v. 28, n. 11, p. 2367, doi. 10.1093/carcin/bgm119
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- Publication type:
- Article
Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-?B and Mat1A genes in the early stages of rat liver carcinogenesis.
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- Carcinogenesis, 2005, v. 26, n. 2, p. 417
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- Publication type:
- Article
Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.
- Published in:
- International Journal of Cancer, 2008, v. 123, n. 9, p. 2057, doi. 10.1002/ijc.23720
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- Publication type:
- Article
Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis.
- Published in:
- International Journal of Cancer, 2007, v. 121, n. 11, p. 2410, doi. 10.1002/ijc.22940
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- Publication type:
- Article
Polygenic control of hepatocarcinogenesis in Copenhagen × F344 rats.
- Published in:
- International Journal of Cancer, 2004, v. 111, n. 1, p. 9, doi. 10.1002/ijc.20225
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- Publication type:
- Article
Phenotypic reversion of rat neoplastic liver nodules is under genetic control.
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- International Journal of Cancer, 2003, v. 105, n. 1, p. 70, doi. 10.1002/ijc.11044
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- Publication type:
- Article
Functional role of SGK3 in PI3K/Pten driven liver tumor development.
- Published in:
- 2019
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- Publication type:
- journal article
Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice.
- Published in:
- 2018
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- Publication type:
- journal article
The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease.
- Published in:
- International Journal of Cancer, 2010, v. 126, n. 5, p. 1275, doi. 10.1002/ijc.24650
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- Publication type:
- Article
Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury.
- Published in:
- Annals of Gastroenterology, 2018, v. 31, n. 5, p. 552, doi. 10.20524/aog.2018.0288
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- Publication type:
- Article
Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma.
- Published in:
- Cell Death & Disease, 2024, v. 15, n. 6, p. 1, doi. 10.1038/s41419-024-06839-8
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- Publication type:
- Article
Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis.
- Published in:
- Cell Death & Disease, 2023, v. 14, n. 7, p. 1, doi. 10.1038/s41419-023-05958-y
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- Publication type:
- Article
Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma.
- Published in:
- Cell Death & Disease, 2021, v. 12, n. 10, p. 1, doi. 10.1038/s41419-021-04206-5
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- Publication type:
- Article
Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression.
- Published in:
- Cell Death & Disease, 2021, v. 12, n. 2, p. 1, doi. 10.1038/s41419-021-03488-z
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- Publication type:
- Article
Oncogene-dependent function of BRG1 in hepatocarcinogenesis.
- Published in:
- Cell Death & Disease, 2020, v. 11, n. 2, p. 1, doi. 10.1038/s41419-020-2289-3
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- Publication type:
- Article
MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment.
- Published in:
- Cell Death & Disease, 2019, v. 10, n. 2, p. 1, doi. 10.1038/s41419-019-1389-4
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- Publication type:
- Article