Frontal Encephalocele Plus Epilepsy: A Case Report and Review of the Literature.

Yamazaki, Ken; Kanaya, Kohei; Uda, Takehiro; Fukuyama, Tetsuhiro; Nishioka, Makoto; Hoshino, Yumi; Kaneko, Tomoki; Hardian, Ridzky Firmansyah; Yamazaki, Daisuke; Kuwabara, Haruki; Funato, Kohei; Horiuchi, Tetsuyoshi

An encephalocele is a pathological brain herniation caused by osseous dural defects. Encephaloceles are known to be regions of epileptogenic foci. We describe the case of a 44-year-old woman with refractory epilepsy associated with a frontal skull base encephalocele. Epilepsy surgery for encephalocele resection was performed; however, the epilepsy was refractory. A second epilepsy surgery for frontal lobectomy using intraoperative electroencephalography was required to achieve adequate seizure control. Previous reports have shown that only encephalocele resection can result in good seizure control, and refractory epilepsy due to frontal lobe encephalocele has rarely been reported. To the best of our knowledge, this is the first report of frontal encephalocele plus epilepsy in which good seizure control using only encephalocele resection was difficult to achieve. Herein, we describe the possible mechanisms of encephalocele plus epilepsy and the surgical strategy for refractory epilepsy with encephalocele, including a literature review.

EPILEPSY; ENCEPHALOCELE; EPILEPSY surgery; SKULL base; FRONTAL lobe

Brain Sciences (2076-3425), 2023, Vol 13, Issue 1, p115

2076-3425

Academic Journal

10.3390/brainsci13010115