Works matching Motor neurons

Results: 5000

Supraphysiological expression of survival motor neuron protein from an adenovirus vector does not adversely affect cell function.

Published in:

Biochemistry & Cell Biology, 2013, v. 91, n. 4, p. 252, doi. 10.1139/bcb-2012-0094

By:

Goulet, Benoit B.;
McFall, Emily R.;
Wong, Carmen M.;
Kothary, Rashmi;
Parks, Robin J.

Publication type:

Article

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.

Published in:

PLoS Genetics, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pgen.1006680

By:

Kline, Rachel A.;
Kaifer, Kevin A.;
Osman, Erkan Y.;
Carella, Francesco;
Tiberi, Ariana;
Ross, Jolill;
Pennetta, Giuseppa;
Lorson, Christian L.;
Murray, Lyndsay M.

Publication type:

Article

Motor Band Sign in Motor Neuron Disease: A Marker for Upper Motor Neuron Involvement.

Published in:

Canadian Journal of Neurological Sciences, 2023, v. 50, n. 3, p. 373, doi. 10.1017/cjn.2022.52

By:

Chung, Hee Sahng;
Melkus, Gerd;
Bourque, Pierre;
Chakraborty, Santanu

Publication type:

Article

Homozygous Survival Motor Neuron 2 Gene Deletion and Sporadic Lower Motor Neuron Disease in Children: Case Report and Literature Review.

Published in:

2013

By:

Liping, Lu;
Hongwei, Ma;
Lin, Wang

Publication type:

Case Study

Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study.

Published in:

Brain Pathology, 2025, v. 35, n. 1, p. 1, doi. 10.1111/bpa.13286

By:

Murakami, Aya;
Koga, Shunsuke;
Fujioka, Shinsuke;
White, Adrianna E.;
Bieniek, Kevin F.;
Sekiya, Hiroaki;
DeJesus‐Hernandez, Mariely;
Finch, NiCole A.;
van Blitterswijk, Marka;
Nakamura, Masataka;
Tsuboi, Yoshio;
Murray, Melissa E.;
Wszolek, Zbigniew K.;
Dickson, Dennis W.

Publication type:

Article

Superconditioning TMS for examining upper motor neuron function in MND.

Published in:

Experimental Brain Research, 2019, v. 237, n. 8, p. 2087, doi. 10.1007/s00221-019-05573-4

By:

Calancie, Blair;
Young, Eufrosina;
Watson, Mary Lou;
Wang, Dongliang;
Alexeeva, Natalia

Publication type:

Article

PuraMatrix hydrogel enhances the expression of motor neuron progenitor marker and improves adhesion and proliferation of motor neuron-like cells.

Published in:

Iranian Journal of Basic Medical Sciences, 2020, v. 23, n. 4, p. 431, doi. 10.22038/ijbms.2020.39797.9434

By:

Darvishi, Marzieh;
Hamidabadi, Hatef Ghasemi;
Negah, Sajad Sahab;
Moayeri, Ardeshir;
Tiraihi, Taki;
Mirnajafi-Zadeh, Javad;
Jahan-Abad, Ali Jahanbazi;
Shojaei, Amir

Publication type:

Article

Beta-band intermuscular coherence: a novel biomarker of upper motor neuron dysfunction in motor neuron disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 9, p. 2849, doi. 10.1093/brain/aws150

By:

Fisher, Karen M.;
Zaaimi, Boubker;
Williams, Timothy L.;
Baker, Stuart N.;
Baker, Mark R.

Publication type:

Article

Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy.

Published in:

Acta Neuropathologica, 2011, v. 121, n. 4, p. 509, doi. 10.1007/s00401-011-0797-z

By:

Geser, Felix;
Stein, Beth;
Partain, Michael;
Elman, Lauren B.;
McCluskey, Leo F.;
Xie, Sharon X.;
Van Deerlin, Vivianna M.;
Kwong, Linda K.;
Lee, Virginia M.-Y.;
Trojanowski, John Q.

Publication type:

Article

Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy.

Published in:

Journal of Anatomy, 2016, v. 228, n. 3, p. 443, doi. 10.1111/joa.12419

By:

Powis, Rachael A.;
Gillingwater, Thomas H.

Publication type:

Article

Role of EphA4 in Mediating Motor Neuron Death in MND.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9430, doi. 10.3390/ijms22179430

By:

Zhao, Jing;
Stevens, Claire H.;
Boyd, Andrew W.;
Ooi, Lezanne;
Bartlett, Perry F.

Publication type:

Article

Spinal Cord Organoids to Study Motor Neuron Development and Disease.

Published in:

Life (2075-1729), 2023, v. 13, n. 6, p. 1254, doi. 10.3390/life13061254

By:

Buchner, Felix;
Dokuzluoglu, Zeynep;
Grass, Tobias;
Rodriguez-Muela, Natalia

Publication type:

Article

Targeting the full length of the motor end plate regions in the mouse forelimb increases the uptake of Fluoro-Gold into corresponding spinal cord motor neurons.

Published in:

Frontiers in Neurology, 2013, v. 4, p. 1, doi. 10.3389/fneur.2013.00058

By:

Tosolini, Andrew Paul;
Mohan, Rahul;
Morris, Renée

Publication type:

Article

Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy.

Published in:

Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0806-3

By:

Rehorst, Wiebke A.;
Thelen, Maximilian P.;
Nolte, Hendrik;
Türk, Clara;
Cirak, Sebahattin;
Peterson, Jonathan M.;
Wong, G. William;
Wirth, Brunhilde;
Krüger, Marcus;
Winter, Dominic;
Kye, Min Jeong

Publication type:

Article

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 545, doi. 10.3390/cells12040545

By:

Castellanos-Montiel, María José;
Chaineau, Mathilde;
Franco-Flores, Anna Kristyna;
Haghi, Ghazal;
Carrillo-Valenzuela, Dulce;
Reintsch, Wolfgang E.;
Chen, Carol X.-Q.;
Durcan, Thomas M.

Publication type:

Article

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1127, doi. 10.3390/cells10051127

By:

Cutarelli, Alessandro;
Martínez-Rojas, Vladimir A.;
Tata, Alice;
Battistella, Ingrid;
Rossi, Daniela;
Arosio, Daniele;
Musio, Carlo;
Conti, Luciano;
Pession, Andrea

Publication type:

Article

Highly Efficient Conversion of Motor Neuron-Like NSC-34 Cells into Functional Motor Neurons by Prostaglandin E2.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1741, doi. 10.3390/cells9071741

By:

Nango, Hiroshi;
Kosuge, Yasuhiro;
Sato, Masaki;
Shibukawa, Yoshiyuki;
Aono, Yuri;
Saigusa, Tadashi;
Ito, Yoshihisa;
Ishige, Kumiko

Publication type:

Article

The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord.

Published in:

Cells (2073-4409), 2020, v. 9, n. 2, p. 502, doi. 10.3390/cells9020502

By:

Genc, Baris;
Gozutok, Oge;
Kocak, Nuran;
Ozdinler, P. Hande

Publication type:

Article

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation.

Published in:

BMC Molecular & Cell Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12860-021-00343-z

By:

Solomon, Emilia;
Davis-Anderson, Katie;
Hovde, Blake;
Micheva-Viteva, Sofiya;
Harris, Jennifer Foster;
Twary, Scott;
Iyer, Rashi

Publication type:

Article

Duple-MONDNet: duple deep learning-based mobile net for motor neuron disease identification.

Published in:

Turkish Journal of Medical Sciences, 2025, v. 55, n. 1, p. 140, doi. 10.55730/1300-0144.5952

By:

HELEN, Sony;
JAWHAR, Joseph

Publication type:

Article

Three-Dimensional Mapping of Retrograde Multi-Labeled Motor Neuron Columns in the Spinal Cord.

Published in:

Photonics, 2021, v. 8, n. 5, p. 145, doi. 10.3390/photonics8050145

By:

Xu, Jianyi;
Yin, Xiaofeng;
Qi, Yisong;
Chen, Bo;
Li, Yusha;
Wan, Peng;
Yao, Yingtao;
Zhu, Dan;
Jiang, Baoguo;
Yu, Tingting

Publication type:

Article

Neurotrophic factors in the physiology of motor neurons and their role in the pathobiology and therapeutic approach to amyotrophic lateral sclerosis.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1238453

By:

Stansberry, Wesley M.;
Pierchala, Brian A.

Publication type:

Article

Circulating MicroRNAs as Diagnostic Biomarkers for Motor Neuron Disease.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00354

By:

Wang, Lin;
Zhang, Lijuan

Publication type:

Article

Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3878, doi. 10.3390/molecules27123878

By:

Shandilya, Ambika;
Mehan, Sidharth;
Kumar, Sumit;
Sethi, Pranshul;
Narula, Acharan S.;
Alshammari, Abdulrahman;
Alharbi, Metab;
Alasmari, Abdullah F.

Publication type:

Article

Spinal astrocyte dysfunction drives motor neuron loss in late-onset spinal muscular atrophy.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 5, p. 611, doi. 10.1007/s00401-023-02554-4

By:

Schmitt, Linda-Isabell;
David, Christina;
Steffen, Rebecca;
Hezel, Stefanie;
Roos, Andreas;
Schara-Schmidt, Ulrike;
Kleinschnitz, Christoph;
Leo, Markus;
Hagenacker, Tim

Publication type:

Article

CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement.

Published in:

Biomedicines, 2021, v. 9, n. 11, p. 1623, doi. 10.3390/biomedicines9111623

By:

Simonini, Cecilia;
Zucchi, Elisabetta;
Bedin, Roberta;
Martinelli, Ilaria;
Gianferrari, Giulia;
Fini, Nicola;
Sorarù, Gianni;
Liguori, Rocco;
Vacchiano, Veria;
Mandrioli, Jessica

Publication type:

Article

Survival motor neuron protein protects H9c2 cardiomyocytes from hypoxia‐induced cell injury by reducing apoptosis.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2020, v. 47, n. 11, p. 1808, doi. 10.1111/1440-1681.13369

By:

Zhong, Xiao;
Song, Ziguang;
Song, Xiang

Publication type:

Article

MotomiRs: miRNAs in Motor Neuron Function and Disease.

Published in:

Frontiers in Molecular Neuroscience, 2017, v. 10, p. 1, doi. 10.3389/fnmol.2017.00127

By:

Hawley, Zachary C. E.;
Campos-Melo, Danae;
Droppelmann, Cristian A.;
Strong, Michael J.

Publication type:

Article

A lower motor neuron disease in takahē (Porphyrio hochstetteri) is an endoplasmic reticulum storage disease.

Published in:

New Zealand Veterinary Journal, 2023, v. 71, n. 4, p. 186, doi. 10.1080/00480169.2023.2190549

By:

Jolly, RD;
Perrott, MR;
Alley, MR;
Hunter, SA;
Pas, A;
Beard, H;
Hemsley, KM;
Greaves, G

Publication type:

Article

Loss of ALS2 Function Is Insufficient to Trigger Motor Neuron Degeneration in Knock-Out Mice But Predisposes Neurons to Oxidative Stress.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 33, p. 7567, doi. 10.1523/JNEUROSCI.1645-05.2005

By:

Huaibin Cai;
Xian Lin;
Chengsong Xie;
Laird, Fiona M.;
Chen Lai;
Hongjin Wen;
Hsueh-Cheng Chiang;
Hoon Shim;
Farah, Mohamed H.;
Hoke, Ahmet;
Price, Donald L.;
Wong, Philip C.

Publication type:

Article

A Platform to Understand Amyotrophic Lateral Sclerosis (ALS) and Extend Human Motor Neurons Longevity.

Published in:

International Journal of Morphology, 2019, v. 37, n. 4, p. 1203, doi. 10.4067/s0717-95022019000401203

By:

Cáceres, D. E.;
Torres, F. C.;
Castillo, C. A.;
Maureira, A.;
Franco-Campos, F. A.;
Osorio, M.;
Segovia, R.;
Tapia, J. C.;
Carrasco, M. A.

Publication type:

Article

The spectrum of lower motor neuron syndromes.

Published in:

Journal of Neurology, 2003, v. 250, n. 11, p. 1279, doi. 10.1007/s00415-003-0235-9

By:

van den Berg-Vos, R. M.;
van den Berg, L. H.;
Visser, J.;
de Visser, M.;
Franssen, H.;
Wokke, J. H. J.

Publication type:

Article

Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis.

Published in:

Journal of Neurology, 2000, v. 247, p. I17, doi. 10.1007/BF03161151

By:

Shaw, Pamela J.;
Eggett, C. J.

Publication type:

Article

Review: Microglia in motor neuron disease.

Published in:

Neuropathology & Applied Neurobiology, 2021, v. 47, n. 2, p. 179, doi. 10.1111/nan.12640

By:

Ashford, B. A.;
Boche, D.;
Cooper‐Knock, J.;
Heath, P. R.;
Simpson, J. E.;
Highley, J. R.

Publication type:

Article

A neuromechanical model exploring the role of the common inhibitor motor neuron in insect locomotion.

Published in:

Biological Cybernetics, 2020, v. 114, n. 1, p. 23, doi. 10.1007/s00422-019-00811-y

By:

Naris, Mantas;
Szczecinski, Nicholas S.;
Quinn, Roger D.

Publication type:

Article

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles.

Published in:

FEBS Open Bio, 2021, v. 11, n. 2, p. 494, doi. 10.1002/2211-5463.13059

By:

Otake, Kentaro;
Adachi‐Tominari, Keiko;
Nagai, Hiroaki;
Saito, Masayo;
Sano, Osamu;
Hirozane, Yoshihiko;
Iwata, Hidehisa

Publication type:

Article

Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats.

Published in:

Frontiers in Physiology, 2024, p. 1, doi. 10.3389/fphys.2024.1488951

By:

Lewis, Ryan D.;
Keilholz, Amy N.;
Smith, Catherine L.;
Burd, Ethan A.;
Nichols, Nicole L.

Publication type:

Article

Strategy for Treating Motor Neuron Diseases Using a Fusion Protein of Botulinum Toxin Binding Domain and Streptavidin for Viral Vector Access: Work in Progress.

Published in:

Toxins, 2010, v. 2, n. 12, p. 2872, doi. 10.3390/toxins2122872

By:

Drachman, Daniel B.;
Adams, Robert N.;
Balasubramanian, Uma;
Yang Lu

Publication type:

Article

Subacute combined degeneration of the spinal cord masking motor neuron disease: a case report.

Published in:

2019

By:

Loveland, Paula;
Wong, Aaron;
Vivekanandam, Vinojini;
Lim, Wen Kwang

Publication type:

journal article

MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164103

By:

Glajch, Kelly E.;
Ferraiuolo, Laura;
Mueller, Kaly A.;
Stopford, Matthew J.;
Prabhkar, Varsha;
Gravanis, Achille;
Shaw, Pamela J.;
Sadri-Vakili, Ghazaleh

Publication type:

Article

Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161816

By:

Tefera, Tesfaye W.;
Wong, Yide;
Barkl-Luke, Mallory E.;
Ngo, Shyuan T.;
Thomas, Nicola K.;
McDonald, Tanya S.;
Borges, Karin

Publication type:

Article

Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153399

By:

Han, Yongmei;
Ripley, Barry;
Serada, Satoshi;
Naka, Tetsuji;
Fujimoto, Minoru

Publication type:

Article

p53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.1038276

By:

Buettner, Jannik M.;
Sowoidnich, Leonie;
Gerstner, Florian;
Blanco-Redondo, Beatriz;
Hallermann, Stefan;
Simon, Christian M.

Publication type:

Article

Visual three-dimensional spatial distribution of motor neurons innervating superficial limb muscles in mice.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 01, doi. 10.3389/fncel.2022.904172

By:

Zhidan Qi;
Shuai Han;
Shen Wang;
Xinyi Gu;
Jin Deng;
Chen Huang;
Xiaofeng Yin

Publication type:

Article

Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.

Published in:

Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1527181

By:

Eckardt, Adam;
Marble, Charles;
Fern, Bradley;
Moritz, Henry;
Kotula, Charles;
Ke, Jiayi;
Rebancos, Clarisse;
Robertson, Samantha;
Nishimune, Hiroshi;
Suzuki, Masatoshi

Publication type:

Article

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 13, p. 3811, doi. 10.1523/JNEUROSCI.2396-15.2016

By:

Fallini, Claudia;
Donlin-Asp, Paul G.;
Rouanet, Jeremy P.;
Bassell, Gary J.;
Rossoll, Wilfried

Publication type:

Article

Validity and reliability of an electromyography-based upper limb assessment quantifying selective voluntary motor control in children with upper motor neuron lesions.

Published in:

Science Progress, 2021, p. 1, doi. 10.1177/00368504211008058

By:

Keller, Jeffrey W;
Fahr, Annina;
Balzer, Julia;
Lieber, Jan;
van Hedel, Hubertus JA

Publication type:

Article

A method to investigate muscle target‐specific transcriptional signatures of single motor neurons.

Published in:

Developmental Dynamics, 2023, v. 252, n. 1, p. 208, doi. 10.1002/dvdy.507

By:

Berki, Bianka;
Sacher, Fabio;
Fages, Antoine;
Tschopp, Patrick;
Luxey, Maëva

Publication type:

Article

ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01852-6

By:

Zelina, Pavol;
de Ruiter, Anna Aster;
Kolsteeg, Christy;
van Ginneken, Ilona;
Vos, Harmjan R.;
Supiot, Laura F.;
Burgering, Boudewijn M. T.;
Meye, Frank J.;
Veldink, Jan H.;
van den Berg, Leonard H.;
Pasterkamp, R. Jeroen

Publication type:

Article

ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01852-6

By:

Zelina, Pavol;
de Ruiter, Anna Aster;
Kolsteeg, Christy;
van Ginneken, Ilona;
Vos, Harmjan R.;
Supiot, Laura F.;
Burgering, Boudewijn M. T.;
Meye, Frank J.;
Veldink, Jan H.;
van den Berg, Leonard H.;
Pasterkamp, R. Jeroen

Publication type:

Article