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G protein-coupled receptors: novel targets for drug discovery in cancer.
- Published in:
- 2011
- By:
- Publication type:
- journal article
The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs).
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2020, v. 39, n. 1, p. 1, doi. 10.1186/s13046-020-01667-y
- By:
- Publication type:
- Article
G-Protein-Coupled Estrogen Receptor Expression in Rat Uterine Artery Is Increased by Pregnancy and Induces Dilation in a Ca 2+ and ERK1/2 Dependent Manner.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 5996, doi. 10.3390/ijms23115996
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- Publication type:
- Article
S100A4 Is Involved in Stimulatory Effects Elicited by the FGF2/FGFR1 Signaling Pathway in Triple-Negative Breast Cancer (TNBC) Cells.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4720, doi. 10.3390/ijms22094720
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- Publication type:
- Article
Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7797, doi. 10.3390/ijms21207797
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- Publication type:
- Article
GPCR Modulation in Breast Cancer.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3840, doi. 10.3390/ijms19123840
- By:
- Publication type:
- Article
Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMT.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 7, p. 2011, doi. 10.3390/ijms19072011
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- Publication type:
- Article
G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts.
- Published in:
- International Journal of Molecular Sciences, 2017, v. 18, n. 12, p. 2713, doi. 10.3390/ijms18122713
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- Publication type:
- Article
GPCRs and cancer.
- Published in:
- Acta Pharmacologica Sinica, 2012, v. 33, n. 3, p. 351, doi. 10.1038/aps.2011.183
- By:
- Publication type:
- Article
Crucial Role of Phospholamban Phosphorylation and S-Nitrosylation in the Negative Lusitropism Induced by 17β-estradiol in the Male Rat Heart.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2011, v. 28, n. 1, p. 41, doi. 10.1159/000331712
- By:
- Publication type:
- Article
Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28062-9
- By:
- Publication type:
- Article
Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells—identification of a novel androgen response element.
- Published in:
- Nucleic Acids Research, 2010, v. 38, n. 16, p. 5351, doi. 10.1093/nar/gkq278
- By:
- Publication type:
- Article
Composition, Antifungal and Antiproliferative Activities of the Hydrodistilled Oils from Leaves and Flower Heads of Pterocephalus nestorianus N ábělek.
- Published in:
- Chemistry & Biodiversity, 2017, v. 14, n. 7, p. n/a, doi. 10.1002/cbdv.201700009
- By:
- Publication type:
- Article
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs).
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1337-2
- By:
- Publication type:
- Article
Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1056-8
- By:
- Publication type:
- Article
miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0767-6
- By:
- Publication type:
- Article
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells.
- Published in:
- Journal of Translational Medicine, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12967-022-03463-y
- By:
- Publication type:
- Article
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Translational signaling and systems biology.
- Published in:
- 2021
- By:
- Publication type:
- Editorial
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
- Published in:
- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01654-0
- By:
- Publication type:
- Article
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
- Published in:
- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01654-0
- By:
- Publication type:
- Article
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
- Published in:
- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01654-0
- By:
- Publication type:
- Article
GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response.
- Published in:
- Scientific Reports, 2016, p. 24354, doi. 10.1038/srep24354
- By:
- Publication type:
- Article
Pharmacotherapeutic Targeting of G Protein-Coupled Receptors in Oncology: Examples of Approved Therapies and Emerging Concepts.
- Published in:
- Drugs, 2017, v. 77, n. 9, p. 951, doi. 10.1007/s40265-017-0738-9
- By:
- Publication type:
- Article
Computational Approaches for the Discovery of GPER Targeting Compounds.
- Published in:
- Frontiers in Endocrinology, 2020, p. N.PAG, doi. 10.3389/fendo.2020.00517
- By:
- Publication type:
- Article
Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling.
- Published in:
- AAPS Journal, 2016, v. 18, n. 2, p. 305, doi. 10.1208/s12248-016-9881-6
- By:
- Publication type:
- Article
Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands.
- Published in:
- AAPS Journal, 2016, v. 18, n. 1, p. 41, doi. 10.1208/s12248-015-9844-3
- By:
- Publication type:
- Article
Pregnancy Augments G Protein Estrogen Receptor (GPER) Induced Vasodilation in Rat Uterine Arteries via the Nitric Oxide - cGMP Signaling Pathway.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141997
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- Publication type:
- Article
GPER Mediates Cardiotropic Effects in Spontaneously Hypertensive Rat Hearts.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0069322
- By:
- Publication type:
- Article
The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes.
- Published in:
- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016631
- By:
- Publication type:
- Article
DDR1 Affects Metabolic Reprogramming in Breast Cancer Cells by Cross-Talking to the Insulin/IGF System.
- Published in:
- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 926, doi. 10.3390/biom11070926
- By:
- Publication type:
- Article
Fibronectin and type IV collagen activate ERaAF-1 by c-Src pathway: effect on breast cancer cell motility.
- Published in:
- Oncogene, 2004, v. 23, n. 55, p. 8920, doi. 10.1038/sj.onc.1208098
- By:
- Publication type:
- Article
Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation.
- Published in:
- Oncogene, 2002, v. 21, n. 42, p. 6434, doi. 10.1038/sj.onc.1205822
- By:
- Publication type:
- Article
Focal Adhesion Kinase Fine Tunes Multifaced Signals toward Breast Cancer Progression.
- Published in:
- Cancers, 2021, v. 13, n. 4, p. 645, doi. 10.3390/cancers13040645
- By:
- Publication type:
- Article
Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 4, p. 621, doi. 10.3390/cancers13040621
- By:
- Publication type:
- Article
Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 3, p. 543, doi. 10.3390/cancers13030543
- By:
- Publication type:
- Article
The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives.
- Published in:
- Cancers, 2020, v. 12, n. 10, p. 3029, doi. 10.3390/cancers12103029
- By:
- Publication type:
- Article
Differential MicroRNA Landscape Triggered by Estrogens in Cancer Associated Fibroblasts (CAFs) of Primary and Metastatic Breast Tumors.
- Published in:
- Cancers, 2019, v. 11, n. 3, p. 412, doi. 10.3390/cancers11030412
- By:
- Publication type:
- Article
GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Response to “Comment on ‘Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts’”.
- Published in:
- Environmental Health Perspectives, 2016, v. 124, n. 4, p. A65, doi. 10.1289/ehp.1611288
- By:
- Publication type:
- Article
Comment on "Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts".
- Published in:
- 2016
- By:
- Publication type:
- Letter to the Editor
Effects of Atrazine on Estrogen Receptor α-- and G Protein--Coupled Receptor 30--Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts.
- Published in:
- Environmental Health Perspectives, 2015, v. 123, n. 5, p. 493, doi. 10.1289/ehp.1408586
- By:
- Publication type:
- Article
Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts.
- Published in:
- Environmental Health Perspectives, 2012, v. 120, n. 8, p. 1177, doi. 10.1289/ehp.1104526
- By:
- Publication type:
- Article
G-Protein--Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells.
- Published in:
- Environmental Health Perspectives, 2008, v. 116, n. 12, p. 1648, doi. 10.1289/ehp.11297
- By:
- Publication type:
- Article
Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF.
- Published in:
- EMBO Journal, 2009, v. 28, n. 5, p. 523, doi. 10.1038/emboj.2008.304
- By:
- Publication type:
- Article
Harnessing sample preparation for RNA-sequencing toward a reliable bioinformatics analysis.
- Published in:
- Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05585-x
- By:
- Publication type:
- Article
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells.
- Published in:
- Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05269-6
- By:
- Publication type:
- Article
Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth.
- Published in:
- Breast Cancer Research & Treatment, 2014, v. 146, n. 2, p. 273, doi. 10.1007/s10549-014-3017-4
- By:
- Publication type:
- Article
GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.
- Published in:
- Breast Cancer Research & Treatment, 2012, v. 133, n. 3, p. 1025, doi. 10.1007/s10549-011-1901-8
- By:
- Publication type:
- Article
17β-Estradiol enhances α integrin subunit gene expression through ERα-Sp1 interaction and reduces cell motility and invasion of ERα-positive breast cancer cells.
- Published in:
- Breast Cancer Research & Treatment, 2011, v. 124, n. 1, p. 63, doi. 10.1007/s10549-009-0713-6
- By:
- Publication type:
- Article