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High clonality of Mycobacterium avium subsp. paratuberculosis field isolates from red deer revealed by two different methodological approaches of comparative genomic analysis.
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- Frontiers in Veterinary Science, 2024, p. 1, doi. 10.3389/fvets.2024.1301667
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- Article
Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34354-x
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- Article
Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin.
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- Journal of Amino Acids, 2012, p. 1, doi. 10.1155/2012/206083
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- Article
The Spike Mutants Website: A Worldwide Used Resource against SARS-CoV-2.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13082, doi. 10.3390/ijms232113082
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Structural Evolution of Delta (B.1.617.2) and Omicron (BA.1) Spike Glycoproteins.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8680, doi. 10.3390/ijms23158680
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- Article
Transcriptomic Characterization of Cow, Donkey and Goat Milk Extracellular Vesicles Reveals Their Anti-inflammatory and Immunomodulatory Potential.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12759, doi. 10.3390/ijms222312759
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Altered Local Interactions and Long-Range Communications in UK Variant (B.1.1.7) Spike Glycoprotein.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5464, doi. 10.3390/ijms22115464
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Multiple Recombination Events and Strong Purifying Selection at the Origin of SARS-CoV-2 Spike Glycoprotein Increased Correlated Dynamic Movements.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 80, doi. 10.3390/ijms22010080
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- Article
A gene expression atlas for different kinds of stress in the mouse brain.
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- Scientific Data, 2020, v. 7, n. 1, p. 1, doi. 10.1038/s41597-020-00772-z
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Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein–DNA binding site.
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- Nucleic Acids Research, 2014, v. 42, n. 14, p. 9304, doi. 10.1093/nar/gku654
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Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation.
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- Nucleic Acids Research, 2013, v. 41, n. 22, p. 10110, doi. 10.1093/nar/gkt778
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- Article
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.
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- Nucleic Acids Research, 2009, v. 37, n. 20, p. 6849, doi. 10.1093/nar/gkp669
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- Article
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations.
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- Nucleic Acids Research, 2008, v. 36, n. 17, p. 5645, doi. 10.1093/nar/gkn558
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- Article
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.
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- Nucleic Acids Research, 2008, v. 36, n. 17, p. 5635, doi. 10.1093/nar/gkn557
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- Article
The open state of human topoisomerase I as probed by molecular dynamics simulation.
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- Nucleic Acids Research, 2007, v. 35, n. 9, p. 3032, doi. 10.1093/nar/gkm199
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- Article
The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant.
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- Nucleic Acids Research, 2006, v. 34, n. 18, p. 5093, doi. 10.1093/nar/gkl670
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- Article
Posterior fossa ependymoma in neurodevelopmental syndrome caused by a de novo germline pathogenic POLR2A variant.
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- American Journal of Medical Genetics. Part A, 2022, v. 188, n. 9, p. 2796, doi. 10.1002/ajmg.a.62869
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- Article
Broadening the phenotypic spectrum of Beta3GalT6‐associated phenotypes.
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- American Journal of Medical Genetics. Part A, 2021, v. 185, n. 10, p. 3153, doi. 10.1002/ajmg.a.62399
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- Article
Microarray gene expression profiling of neural tissues in bovine spastic paresis.
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- BMC Veterinary Research, 2013, v. 9, n. 1, p. 1, doi. 10.1186/1746-6148-9-122
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- Article
An amber compatible molecular mechanics force field for the anticancer drug topotecan.
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- Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2010, v. 127, n. 4, p. 293, doi. 10.1007/s00214-009-0715-9
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- Article
Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines.
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- GigaScience, 2018, v. 7, n. 10, p. N.PAG, doi. 10.1093/gigascience/giy062
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- Article
Solvent Dependency of the UV-Vis Spectrum of Indenoisoquinolines: Role of Keto-Oxygens as Polarity Interaction Probes.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073881
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- Article
Binding of an Indenoisoquinoline to the Topoisomerase- DNA Complex Induces Reduction of Linker Mobility and Strengthening of Protein-DNA Interaction.
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- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051354
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- Article
Identification of a Short Region on Chromosome 6 Affecting Direct Calving Ease in Piedmontese Cattle Breed.
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- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050137
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- Article
Structural and Dynamical Effects Induced by the Anticancer Drug Topotecan on the Human Topoisomerase I -- DNA Complex.
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- PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0010934
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- Article
Comparison of colostrum and milk extracellular vesicles small RNA cargo in water buffalo.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67249-6
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- Article
Not just a Snapshot: An Italian Longitudinal Evaluation of Stability of Gut Microbiota Findings in Parkinson's Disease.
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- Brain Sciences (2076-3425), 2022, v. 12, n. 6, p. 739, doi. 10.3390/brainsci12060739
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- Article
Treatment-Emergent Cilgavimab Resistance Was Uncommon in Vaccinated Omicron BA.4/5 Outpatients.
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- Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1538, doi. 10.3390/biom13101538
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Structural and Dynamic Characterization of the C313Y Mutation in Myostatin Dimeric Protein, Responsible for the "Double Muscle" Phenotype in Piedmontese Cattle.
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- Frontiers in Genetics, 2016, p. 1, doi. 10.3389/fgene.2016.00014
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Modeling conformational transitions in kinases by molecular dynamics simulations: achievements, difficulties, and open challenges.
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- Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00128
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- Article
Smyd2 conformational changes in response to p53 binding: role of the C‐terminal domain.
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- Molecular Oncology, 2019, v. 13, n. 6, p. 1450, doi. 10.1002/1878-0261.12502
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- Article
RNA-Sequencing for profiling goat milk transcriptome in colostrum and mature milk.
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- BMC Veterinary Research, 2016, v. 12, p. 1, doi. 10.1186/s12917-016-0881-7
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- Article
Signatures of selection in five Italian cattle breeds detected by a 54K SNP panel.
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- Molecular Biology Reports, 2014, v. 41, n. 2, p. 957, doi. 10.1007/s11033-013-2940-5
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Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines.
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- Investigational New Drugs, 2007, v. 25, n. 5, p. 491, doi. 10.1007/s10637-007-9070-7
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- Article
Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study.
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- Nucleic Acids Research, 2005, v. 33, n. 10, p. 3339, doi. 10.1093/nar/gki642
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- Article
Protein concerted motions in the DNA–human topoisomerase I complex.
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- Nucleic Acids Research, 2003, v. 31, n. 5, p. 1525, doi. 10.1093/nar/gkg242
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- Article
Muscle transcriptome analysis identifies genes involved in ciliogenesis and the molecular cascade associated with intramuscular fat content in Large White heavy pigs.
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- PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0233372
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ELIXIR-IT HPC@CINECA: high performance computing resources for the bioinformatics community.
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- BMC Bioinformatics, 2020, v. 21, n. 10, p. N.PAG, doi. 10.1186/s12859-020-03565-8
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- Article
HPC-REDItools: a novel HPC-aware tool for improved large scale RNA-editing analysis.
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- BMC Bioinformatics, 2020, v. 21, n. 10, p. N.PAG, doi. 10.1186/s12859-020-03562-x
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- Article
DROPA: DRIP-seq optimized peak annotator.
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- BMC Bioinformatics, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12859-019-3009-9
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- Article
Molecular dynamics recipes for genome research.
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- Briefings in Bioinformatics, 2018, v. 19, n. 5, p. 853, doi. 10.1093/bib/bbx006
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- Article
Genetic Characterization of a Novel Equus caballus Papillomavirus Isolated from a Thoroughbred Mare.
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- Viruses (1999-4915), 2023, v. 15, n. 3, p. 650, doi. 10.3390/v15030650
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- Article
Equus caballus Papillomavirus Type-9 (EcPV9): First Detection in Asymptomatic Italian Horses.
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- Viruses (1999-4915), 2022, v. 14, n. 9, p. 2050, doi. 10.3390/v14092050
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Detection of Equus Caballus Papillomavirus Type-2 in Asymptomatic Italian Horses.
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- Viruses (1999-4915), 2022, v. 14, n. 8, p. 1696, doi. 10.3390/v14081696
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- Article
Duane retraction syndrome characterized by inner ear agenesis and neurodevelopmental phenotype in an Italian family with a variant in MAFB.
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- Clinical Genetics, 2022, v. 101, n. 3, p. 377, doi. 10.1111/cge.14101
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CoVaCS: a consensus variant calling system.
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- BMC Genomics, 2018, v. 19, p. 1, doi. 10.1186/s12864-018-4508-1
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- Article
Expanding the molecular diversity and phenotypic spectrum of glycerol 3-phosphate dehydrogenase 1 deficiency.
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- Journal of Inherited Metabolic Disease, 2016, v. 39, n. 5, p. 689, doi. 10.1007/s10545-016-9956-7
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- Article
A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function.
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- Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 5, p. 497, doi. 10.1007/s10822-017-0014-9
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High performance computing to support land, climate, and user‐oriented services: The HIGHLANDER Data Portal.
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- Meteorological Applications, 2024, v. 31, n. 2, p. 1, doi. 10.1002/met.2166
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Hyperactive HRAS dysregulates energetic metabolism in fibroblasts from patients with Costello syndrome via enhanced production of reactive oxidizing species.
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- Human Molecular Genetics, 2022, v. 31, n. 4, p. 561, doi. 10.1093/hmg/ddab270
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- Article