Works matching DE "MITOGEN-activated protein kinases"

Results: 5000

Mirdametinib: First Approval.

Published in:

Drugs, 2025, v. 85, n. 7, p. 977, doi. 10.1007/s40265-025-02190-0

By:

Hoy, Sheridan M.

Publication type:

Article

Identification of new prognostic biomarkers for Stage III metastatic melanoma patients.

Published in:

OncoImmunology, 2013, v. 2, n. 9, p. e25564-1, doi. 10.4161/onci.25564

By:

Kakavand, Hojabr;
Scolyer, Richard A.;
Thompson, John F.;
Mann, Graham J.

Publication type:

Article

Mini review: The FDA-approved prescription drugs that target the MAPK signaling pathway in women with breast cancer.

Published in:

Breast Disease, 2021, v. 40, n. 2, p. 51, doi. 10.3233/BD-201063

By:

Khojasteh Poor, Fatemeh;
Keivan, Mona;
Ramazii, Mohammad;
Ghaedrahmati, Farhoodeh;
Anbiyaiee, Amir;
Panahandeh, Samira;
Khoshnam, Seyed Esmaeil;
Farzaneh, Maryam

Publication type:

Article

Streblus asper Lour. exerts MAPK and SKN-1 mediated anti-aging, anti-photoaging activities and imparts neuroprotection by ameliorating Aβ in Caenorhabditis elegans.

Published in:

Nutrition & Healthy Aging, 2021, v. 6, n. 3, p. 211, doi. 10.3233/NHA-210121

By:

Prasanth, Mani Iyer;
Brimson, James Michael;
Sheeja Malar, Dicson;
Prasansuklab, Anchalee;
Tencomnao, Tewin

Publication type:

Article

Transcriptional regulation of human follicular dendritic cell-secreted protein gene by interleukin-6.

Published in:

Odontology, 2025, v. 113, n. 3, p. 1081, doi. 10.1007/s10266-024-01050-9

By:

Jin, Zhenyu;
Tsuruya, Yuto;
Igarashi, Kazuma;
Yamaguchi, Arisa;
Takai, Hideki;
Nakayama, Yohei;
Ogata, Yorimasa

Publication type:

Article

Mesenchymal stem cell-derived exosomal CBLB ameliorates infantile pneumonia progression probably by ubiquitinating MAPK14.

Published in:

Journal of Inflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12950-025-00450-0

By:

Guo, Fang;
Song, Fuxing;
Chen, Zhenjiang;
Niu, Na;
Sun, Lina;
Yan, Min;
Liu, Min

Publication type:

Article

The MAP kinase negative regulator DUSP2 (dual specificity phosphatase 2) is controlled by oncogenic microRNA cluster miR-17-92, miR-106a-363 and miR-106b-25.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14434-z

By:

Tenhaken, Victoria;
Seternes, Ole-Morten;
Cascorbi, Ingolf;
Bruckmueller, Henrike

Publication type:

Article

WISP2/CCN5 revealed as a potential diagnostic biomarker for endometriosis based on machine learning and single-cell transcriptomic analysis.

Published in:

Functional & Integrative Genomics, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10142-025-01631-z

By:

Dou, Sheng;
Ling, Shaohua;
Nong, Weihua;
Wei, Bixiao;
Huang, Yuehua;
Li, Guangjing;
Wang, Rong;
Qin, Haimei

Publication type:

Article

蒲公英多酚的抑菌和抗炎活性研究.

Published in:

China Surfactant Detergent & Cosmetics (2097-2806), 2025, v. 55, n. 5, p. 633, doi. 10.3969/j.issn.2097-2806.2025.05.012

By:

谢诗雅;
刘明巍;
肖雷;
胡绍霖

Publication type:

Article

Myeloid-derived MANF ameliorates ethanol-induced liver injury by enhancing microRNA-223 expression.

Published in:

Journal of Gastroenterology, 2025, v. 60, n. 7, p. 877, doi. 10.1007/s00535-025-02240-0

By:

Xie, Huiyuan;
Zhang, Pingping;
Yang, Shanru;
Du, Jia;
Ren, Yan;
Gao, Xianxian;
Li, Na;
Yang, Tao;
Ma, Yang;
Hou, Xin

Publication type:

Article

Juvenile hormone interacts with insulin and potentiates the ERK signaling pathway for female reproduction in locusts.

Published in:

Entomologia Generalis, 2025, v. 45, n. 2, p. 547, doi. 10.1127/entomologia/2025/3055

By:

Li, Lunjie;
Yang, Libin;
Yu, Guangze;
Guo, Mingfang;
Liu, Lijun;
Xu, Mengru;
Fu, Xiaoyan;
Zhang, Lin-Jie;
Jing, Yu-Pu

Publication type:

Article

MiR-217 participates in the progression of postmenopausal osteoporosis by regulating the OPG/RANKL/RANK pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-06001-w

By:

Yang, Xiaoxia;
Jin, Qihua;
Guo, Lihua

Publication type:

Article

SPAG6 Promotes Multiple Myeloma Through Activation of the MAPK/ERK Signaling Pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1572621

By:

Li, Junnan;
Yan, Xinyu;
Ding, Li;
Yin, Jiaxiu;
Li, Ping;
Liu, Lin

Publication type:

Article

柳叶蜡梅多糖对大鼠急性胃黏膜损伤的保护机制研究.

Published in:

Acta Agriculturae Zhejiangensis, 2025, v. 37, n. 5, p. 1009, doi. 10.3969/j.issn.1004-1524.20240827

By:

陈琳;
顾青

Publication type:

Article

Beyond division and morphogenesis: Considering the emerging roles of septins in plasma membrane homeostasis and cell wall integrity in human fungal pathogens.

Published in:

PLoS Pathogens, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.ppat.1013226

By:

Martinez Barrera, Stephani;
Kozubowski, Lukasz

Publication type:

Article

Basal association of a transcription factor favors early gene expression.

Published in:

PLoS Genetics, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.pgen.1011710

By:

Pinheiro, Sandrine;
Nadal-Ribelles, Mariona;
Solé, Carme;
Vincenzetti, Vincent;
Dusserre, Yves;
Posas, Francesc;
Pelet, Serge

Publication type:

Article

Study on the mechanism of Tongjing Yihao decoction in the treatment of oligoasthenozoospermia based on network pharmacology and molecular docking.

Published in:

Chinese Journal of Bioprocess Engineering, 2025, v. 23, n. 3, p. 301, doi. 10.3969/j.issn.1672-3678.2025.03.008

By:

TIAN Zhaohui;
LIU Jia;
XIE Weiquan;
XIA Wei;
YANG Chao;
ZHANG Jinhong;
ZENG Qingqi

Publication type:

Article

Glutamate activates the MAPK pathway by inhibiting LPAR1 expression and promotes anlotinib resistance in thyroid cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02853-0

By:

Liu, Bin;
Peng, Ying;
Su, Yanjun;
Diao, Chang;
Cha, Liansheng;
Cheng, Ruochuan

Publication type:

Article

Effects of Gandou Fumu Decoction on hepatic fibrosis, iron metabolism, and ferroptosis in patients with hepatolenticular degeneration.

Published in:

Journal of Beijing University of Traditional Chinese Medicine, 2025, v. 48, n. 5, p. 625, doi. 10.3969/j.issn.1006-2157.2025.05.005

By:

Chenling, ZHAO;
Guofang, YU;
Liwei, TIAN;
Mengying, ZHANG;
Lulu1, TANG;
Wenming1, YANG;
Ting1, DONG

Publication type:

Article

Dauriporphine inhibited lung cancer cell viability, motility, and energy metabolism through the miR-424-5p/MAPK14 axis.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00473-w

By:

Du, Yan-Jia;
Lv, Jin-Peng;
Fu, Yao;
Lan, Meng;
Li, Jing-Feng;
Zhang, Hui;
Wu, Nan

Publication type:

Article

Successful treatment of Rosai‐Dorfman disease in the era of targeted therapy.

Published in:

2025

By:

Ngo, Trung Quang;
Dorwal, Pranav;
Oh, Danielle

Publication type:

Letter to the Editor

The PIN Gene Family in Cucumber (Cucumis sativus L.): Genome-Wide Identification and Gene Expression Analysis in Phytohormone and Abiotic Stress Response.

Published in:

Plants (2223-7747), 2025, v. 14, n. 11, p. 1566, doi. 10.3390/plants14111566

By:

Zhang, Yongxue;
Zhu, Kaili;
Shen, Weiyao;
Cui, Jiawei;
Miao, Chen;
Lu, Panling;
Wu, Shaofang;
Zhu, Cuifang;
Jin, Haijun;
Zhang, Hongmei;
Chang, Liying;
Ding, Xiaotao

Publication type:

Article

Limosilactobacillus fermentum MG4244 Protects Against Metabolic and Inflammatory Stress in Caenorhabditis elegans.

Published in:

Foods, 2025, v. 14, n. 11, p. 1995, doi. 10.3390/foods14111995

By:

Kim, Yebin;
Deji-Oloruntoba, Opeyemi O.;
Choe, Yunji;
Lee, Jiyeon;
Park, Jeongyong;
Kim, Byoungkook;
Choi, Sooim;
Jang, Miran

Publication type:

Article

Recent Advances in Molecular Research and Treatment for Melanoma in Asian Populations.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5370, doi. 10.3390/ijms26115370

By:

Kado, Soichiro;
Komine, Mayumi

Publication type:

Article

Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5206, doi. 10.3390/ijms26115206

By:

Nakadate, Kazuhiko;
Ito, Nozomi;
Kawakami, Kiyoharu;
Yamazaki, Noriko

Publication type:

Article

MAPK15 Prevents IFNB1 Expression by Suppressing Oxidative Stress-Dependent Activation of the JNK-JUN Pathway.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5148, doi. 10.3390/ijms26115148

By:

Taranta, Monia;
Panepinto, Sara;
Galvagni, Federico;
Franci, Lorenzo;
Chiariello, Mario

Publication type:

Article

Factors Contributing to Resistance to Ischemia-Reperfusion Injury in Olfactory Mitral Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5079, doi. 10.3390/ijms26115079

By:

Lee, Choong-Hyun;
Ahn, Ji Hyeon;
Won, Moo-Ho

Publication type:

Article

Characterization and Functional Analysis of a Novel Fungal Immunomodulatory Protein Gene from Ganoderma leucocontextum in B16-F10 Mouse Melanoma Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5063, doi. 10.3390/ijms26115063

By:

Yang, Jiayi;
Jin, Mengyuan;
Zhang, Lida;
Wu, Yingying;
Zhou, Xuanwei

Publication type:

Article

Isomeric 3-Pyridinylmethylcoumarins Differ in Erk1/2-Inhibition and Modulation of BV2 Microglia-Mediated Neuroinflammation.

Published in:

Molecules, 2025, v. 30, n. 11, p. 2452, doi. 10.3390/molecules30112452

By:

Schulzki, Rami;
Apweiler, Matthias;
Röttger, Caroline;
Grathwol, Christoph W.;
Struchtrup, Nora;
Abou El Mirate, Sophia;
Normann, Claus;
Bräse, Stefan;
Fiebich, Bernd L.

Publication type:

Article

Comparative transcriptomic analysis and genome-wide identification provide insights into the potential role of fungal-responsive MAPK cascade genes in tanshinone accumulation in Salvia miltiorrohiza.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1583953

By:

Abozeid, Ann;
Du, Xinru;
Zhang, Lan;
Yang, Furui;
Wu, Jianxiong;
Zhang, Lin;
Cui, Qi;
Yang, Zongqi;
Yang, Dongfeng

Publication type:

Article

Correlation study of LINC02609 and SNHG17 as prognostic biomarkers of kidney renal clear cell carcinoma and therapeutic sensitivity based on public data and In Vitro analysis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1592474

By:

Xing, Chaoqun;
Zou, Weiwei;
Li, Yangqin;
Zhang, Ti;
Yao, Fan;
Yao, Zhi-Yong;
Xing, Xiao-Liang

Publication type:

Article

Treatment of Plexiform Neurofibromas : Current Perspectives on Surgery and Medical Treatment.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 252, doi. 10.3340/jkns.2025.0041

By:

Hwang, Jun Kyu;
Kim, Se Hoon;
Kim, Dong-Seok

Publication type:

Article

Germline Variants in Pediatric Cancer : Based on Oncogenic Pathways.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 350, doi. 10.3340/jkns.2025.0011

By:

Kim, Joo Whan

Publication type:

Article

Utilizing Multi-omics analysis to elucidate the role of mitochondrial gene defects in Gastric cancer progression.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325520

By:

Chu, Jie;
Song, Hanying;
Fu, Kemin;
Xiao, Wei;
Jiang, Jiudong;
Gan, Qixin;
Deng, Bo

Publication type:

Article

Molecular Cloning, Tissue Distribution, and Hypoxia and Ammonia Stress Response of the p38 MAPK of Black Seabream (Acanthopagrus schlegelii).

Published in:

Pakistan Journal of Zoology, 2025, v. 57, n. 3, p. 1313, doi. 10.17582/journal.pjz/20230226020206

By:

Jing Wang;
Tiejin Tong;
Yuanchao Zou;
Xiaoling Xu;
Qiang Wu;
Qingchao Shi

Publication type:

Article

Neolitsea sericea attenuates oxidative stress-induced cell death in human neuroblastoma SH-SY5Y cells via MAPK and NF-κB pathway Inhibition.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10682-1

By:

Shin, Mi Song;
Song, Parkyong;
Choi, Seo Young;
Lee, You Kyeong;
Hwang, Ji Sun;
Son, Hong-Joo;
Kim, Yu-Jin;
Kim, Wanil;
Lee, Kwang Min

Publication type:

Article

Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H<sub>2</sub>O<sub>2</sub>-induced injury in PC12 cells.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04956-1

By:

Wang, Qiaona;
Zhu, Canhe;
Song, Zhaoran;
Qiao, Yunfa;
Hu, Yuefeng;
Hu, Liyun;
Li, Shengjie;
Wang, Renlei

Publication type:

Article

N-Acetyl Cysteine Inhibits Weaning Stress-Induced Intestinal Cell Cycle Arrest in Piglets through Decreasing ERK, JNK, and p38 Phosphorylation.

Published in:

Biocell, 2025, v. 49, n. 5, p. 907, doi. 10.32604/biocell.2025.063568

By:

Guo, Qi;
Xu, Jianxiong;
Cai, Xuan;
Xie, Jiaojiao;
Wu, Siqi

Publication type:

Article

Genetic, inflammatory and immunological biomarkers for the early assessment of allergic asthma: a current update.

Published in:

Polish Journal of Allergology / Alergologia Polska, 2025, v. 12, n. 2, p. 117, doi. 10.5114/pja.2025.151298

By:

Harfouch, Rim M.

Publication type:

Article

Casein kinase 1 epsilon (CK1ε) as a potential therapeutic target in chronic liver disease.

Published in:

Journal of Veterinary Science, 2025, v. 26, n. 3, p. 1, doi. 10.4142/jvs.24321

By:

Leya, Mwense;
Thach Phan Van;
Jong-Won Kim;
Bumseok Kim

Publication type:

Article

Recurrent cellulitis associated with lymphoedema in Noonan syndrome: case reports with RIT1 variants and literature review.

Published in:

Human Genome Variation, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41439-025-00315-1

By:

Kobayashi, Yuki;
Adachi, Takeya;
Tahara, Umi;
Tanaka, Moemi;
Arakawa, Hiroki;
Funatsu, Yohei;
Moritani, Kazunori;
Yamada, Mamiko;
Kosaki, Kenjiro;
Inazumi, Toyoko

Publication type:

Article

Matrix stiffness-induced IKBKE and MAPK8 signaling drives a phenotypic switch from DCIS to invasive breast cancer.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02276-y

By:

Yan, Feifei;
Göransson, Sara;
Olofsson, Helene;
Vogiatzakis, Christos;
Acharekar, Anagha;
Strömblad, Staffan

Publication type:

Article

Correction: Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.

Published in:

2025

By:

Nokin, Marie-Julie;
Bellier, Justine;
Durieux, Florence;
Peulen, Olivier;
Rademaker, Gilles;
Gabriel, Maude;
Monseur, Christine;
Charloteaux, Benoit;
Verbeke, Lieven;
van Laere, Steven;
Roncarati, Patrick;
Herfs, Michael;
Lambert, Charles;
Scheijen, Jean;
Schalkwijk, Casper;
Colige, Alain;
Caers, Jo;
Delvenne, Philippe;
Turtoi, Andrei;
Castronovo, Vincent

Publication type:

Correction Notice

Integrated transcriptomics and proteomics revealed that exogenous spermidine modulated signal transduction and carbohydrate metabolic pathways to enhance heat tolerance of lettuce.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06781-7

By:

Duan, Yipei;
Sun, Wenjing;
Wang, Qian;
Cao, Lingling;
Wang, Huiyu;
Hao, Jinghong;
Han, Yingyan;
Liu, Chaojie

Publication type:

Article

Exercise training exerts beneficial effects on Alzheimer's disease through multiple signaling pathways.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1558078

By:

Kang, Jihe;
Liu, Mei;
Yang, Qiang;
Dang, Xiangji;
Li, Qun;
Wang, Ting;
Qiu, Bin;
Zhang, Yibao;
Guo, Xudong;
Li, Xiaoling;
Liu, Yan

Publication type:

Article

Inhibition of NR2F2 restores hormone therapy response to endocrine refractory breast cancers.

Published in:

Science Translational Medicine, 2025, v. 17, n. 801, p. 1, doi. 10.1126/scitranslmed.adk7786

By:

Cai, Yanyan;
Zhao, Peihua;
Wu, Fan;
Zhao, Huiyong;
Shao, Hong;
Marra, Antonio;
Patel, Payal;
O'Connell, Elizabeth;
Fink, Emma;
Miele, Matthew M.;
Li, Zhuoning;
De Stanchina, Elisa;
Cocco, Emiliano;
Razavi, Pedram;
Toska, Eneda;
Fanning, Sean W.;
Xu, Guotai;
Sablina, Anna A.;
Scaltriti, Maurizio;
Chandarlapaty, Sarat

Publication type:

Article

不同肿瘤中AKR1B10 的表达与作用.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 323, doi. 10.3872/j.issn.1007-385x.2025.03.013

By:

蒋堃;
综述;
曹德良;
吴萍;
审阅

Publication type:

Article

Response to a novel type II RAF inhibitor in diffuse leptomeningeal glioneuronal tumor with BRAF fusion.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf093

By:

Chun, Brie M;
Youngworth, Sandra;
Abtin, Vicki;
Stull, David;
Starkey, Jay;
Kummar, Shivaani

Publication type:

Article

Social jetlag elicits fatty liver via perturbed circulating prolactin rhythm-mediated circadian remodeling of hepatic lipid metabolism.

Published in:

Military Medical Research, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40779-025-00609-z

By:

Zhang, Peng-Zi;
Shi, Ying-Huan;
Guo, Yu-Xin;
Li, Ya-Yuan;
Yin, Hong-Li;
Wu, Tian-Yu;
Zhu, Ye;
Jiang, Jia-Xuan;
Bi, Yan

Publication type:

Article

Myocardial mitochondrial antiviral signaling protein promotes heart Ischemia-reperfusion injury via RIG-I signaling in mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60123-7

By:

Kang, Zhenyu;
Yang, Mengling;
Liu, Yue;
Gui, Yang;
Dong, Yalan;
Zhou, Haifeng;
Zhang, Zili;
Li, Mingyue;
Fan, Heng;
Li, Zheng;
Lu, Junjie;
Li, Junyi;
Zhu, Rui;
Yin, Chengyu;
Liu, Boyi;
Jiang, Feng;
Huang, Kun;
Sarapultsev, Alexey;
Li, Fangfei;
Zhang, Ge

Publication type:

Article