The Impact of Carboxytherapy in Monotherapy and in Combination with Lactobionic or Ferulic Acid and Ascorbic Acid on the Hydration and Viscoelasticity of the Skin Around the Eyes.

Kołodziejczak, Anna; Rybak, Aleksandra; Rotsztejn, Helena

Carboxytherapy is a promising treatment modality with multidirectional effects on the skin; yet, its impact on hydration and viscoelasticity in the delicate periorbital area requires further exploration. This study aimed to evaluate the effects of carboxytherapy as monotherapy and in combination with selected acids on the hydration and viscoelasticity of the skin around the eyes. Thirty-nine participants underwent five weekly treatments, with carboxytherapy applied to the right eye area and carboxytherapy combined with acids (ferulic acid 14% with L-ascorbic acid 12% or lactobionic acid 20%) administered to the left eye area. Skin hydration and viscoelasticity were measured using Corneometer and Cutometer probes, respectively. Statistically significant improvements (p < 0.0001) in viscoelasticity were observed in both treated areas. The combination of carboxytherapy with lactobionic acid led to a modest but statistically insignificant increase in skin hydration. These findings indicate that carboxytherapy, particularly in combination with tested acids, is effective for improving skin viscoelasticity. While its effect on hydration is more pronounced in dry skin, the therapy significantly enhances skin elasticity, supporting its use as a preventative and corrective treatment for age-related changes, including progressive loss of skin density and firmness.

FERULIC acid; STATISTICAL significance; VITAMIN C; VISCOELASTICITY; ELASTICITY

Applied Sciences (2076-3417), 2025, Vol 15, Issue 4, p1876

2076-3417

Academic Journal

10.3390/app15041876