The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy.

Bulancea, Bogdan Petru; Checherita, Laura Elisabeta; Foia, Georgeta Liliana; Stamatin, Ovidiu; Teslaru, Silvia; Lupu, Iulian Costin; Ciobanu, Delia Gabriela; Cernei, Eduard-Radu; Carmen, Grierosu; Postolache, Mariana; Froicu, Eliza Maria; Halitchi, Liliana Gabriela; Aminov, Liana

Xerostomia is a common complication post-radiotherapy in patients with oral cancer. The acute and long-term side effects can considerably reduce the patient's quality of life. The aim of our study was to perform analysis of salivary flow and pH in patients after radiotherapy. Methodology: Clinical and laboratory evaluations were conducted in the 2014–2019 period; out of a total 58 subjects aged between 45 and 84, 28 individuals with oral cancer were selected from St. Spiridon Hospital, Clinic of Maxillo-facial Surgery and Oncology Hospital, Iasi post-radiotherapy. Results: Significant downsized mean values of the hydrogen ion concentration (pH) in saliva (p < 0.001) were recorded in patients after radiotherapy, pH value = 4.580 (±1.051). The mean value of resting salivary flow (MRSF) was significantly lower for the group of patients with radiotherapy (MRSF) = 0.145 mL/min. In 89.29% of cases (25 post-radiotherapy cases), in order to perform oral complex rehabilitation treatment, several endodontic and periodontal treatments were performed. A total of 78.57% of the cases received complex oral rehabilitation as mobile or hybrid prostheses or fixed solutions. Conclusion: Understanding post-radiotherapy salivary biochemic modifications in patients with oral cancer could be of critical importance, in view of related oral disorder prevention.

STOMATOGNATHIC system; ORAL diseases; HYDROGEN-ion concentration; ORAL cancer; REHABILITATION; SALIVARY glands; PROSTHETICS

Applied Sciences (2076-3417), 2022, Vol 12, Issue 8, p3708

2076-3417

Academic Journal

10.3390/app12083708