The main objective of this study was to compare the effectiveness of an innovative multi-nutrient fertiliser (PRO complete) applied foliarly with a standard fertiliser (TRA complete) in triticale crops. PRO complete contained macronutrients (N, P, K), micronutrients (B, Cu, Fe, Mn, Mo, Zn, with Fe and Zn complexed with amino acids), and trace elements (Cr, I, Li, Se—combined with plant extracts). TRA complete had the same quantitative composition, but the micronutrients and trace elements were in mineral form or in complex with EDTA. The experiment was conducted on triticale grown in a soil culture in a growing hall. The triticale yield and quality were determined. The fertilisers had no significant effect on straw yield and macronutrient (N, P, K, Mg, Ca) content in straw and grain. They caused a significant increase in grain yield, but PRO complete was more effective, also in terms of increasing the content of some micronutrients, particularly in straw. Both fertilisers increased the content of Cr, Li, and Se in straw. The application of the fertilisers contributed to some extent to triticale biofortification. In conclusion, the use of foliar multi-compound fertilisers is a beneficial choice for optimising crop yield and quality. However, their chemical composition and dosage should be further developed.