Works matching DE "MITOGEN-activated protein kinases"

Results: 5000

Comparative transcriptomic analysis and genome-wide identification provide insights into the potential role of fungal-responsive MAPK cascade genes in tanshinone accumulation in Salvia miltiorrohiza.

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1583953

By:

Abozeid, Ann;
Du, Xinru;
Zhang, Lan;
Yang, Furui;
Wu, Jianxiong;
Zhang, Lin;
Cui, Qi;
Yang, Zongqi;
Yang, Dongfeng

Publication type:

Article

Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H<sub>2</sub>O<sub>2</sub>-induced injury in PC12 cells.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04956-1

By:

Wang, Qiaona;
Zhu, Canhe;
Song, Zhaoran;
Qiao, Yunfa;
Hu, Yuefeng;
Hu, Liyun;
Li, Shengjie;
Wang, Renlei

Publication type:

Article

N-Acetyl Cysteine Inhibits Weaning Stress-Induced Intestinal Cell Cycle Arrest in Piglets through Decreasing ERK, JNK, and p38 Phosphorylation.

Published in:

Biocell, 2025, v. 49, n. 5, p. 907, doi. 10.32604/biocell.2025.063568

By:

Guo, Qi;
Xu, Jianxiong;
Cai, Xuan;
Xie, Jiaojiao;
Wu, Siqi

Publication type:

Article

Casein kinase 1 epsilon (CK1ε) as a potential therapeutic target in chronic liver disease.

Published in:

Journal of Veterinary Science, 2025, v. 26, n. 3, p. 1, doi. 10.4142/jvs.24321

By:

Leya, Mwense;
Thach Phan Van;
Jong-Won Kim;
Bumseok Kim

Publication type:

Article

Recurrent cellulitis associated with lymphoedema in Noonan syndrome: case reports with RIT1 variants and literature review.

Published in:

Human Genome Variation, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41439-025-00315-1

By:

Kobayashi, Yuki;
Adachi, Takeya;
Tahara, Umi;
Tanaka, Moemi;
Arakawa, Hiroki;
Funatsu, Yohei;
Moritani, Kazunori;
Yamada, Mamiko;
Kosaki, Kenjiro;
Inazumi, Toyoko

Publication type:

Article

Matrix stiffness-induced IKBKE and MAPK8 signaling drives a phenotypic switch from DCIS to invasive breast cancer.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02276-y

By:

Yan, Feifei;
Göransson, Sara;
Olofsson, Helene;
Vogiatzakis, Christos;
Acharekar, Anagha;
Strömblad, Staffan

Publication type:

Article

Correction: Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.

Published in:

2025

By:

Nokin, Marie-Julie;
Bellier, Justine;
Durieux, Florence;
Peulen, Olivier;
Rademaker, Gilles;
Gabriel, Maude;
Monseur, Christine;
Charloteaux, Benoit;
Verbeke, Lieven;
van Laere, Steven;
Roncarati, Patrick;
Herfs, Michael;
Lambert, Charles;
Scheijen, Jean;
Schalkwijk, Casper;
Colige, Alain;
Caers, Jo;
Delvenne, Philippe;
Turtoi, Andrei;
Castronovo, Vincent

Publication type:

Correction Notice

Integrated transcriptomics and proteomics revealed that exogenous spermidine modulated signal transduction and carbohydrate metabolic pathways to enhance heat tolerance of lettuce.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06781-7

By:

Duan, Yipei;
Sun, Wenjing;
Wang, Qian;
Cao, Lingling;
Wang, Huiyu;
Hao, Jinghong;
Han, Yingyan;
Liu, Chaojie

Publication type:

Article

Inhibition of NR2F2 restores hormone therapy response to endocrine refractory breast cancers.

Published in:

Science Translational Medicine, 2025, v. 17, n. 801, p. 1, doi. 10.1126/scitranslmed.adk7786

By:

Cai, Yanyan;
Zhao, Peihua;
Wu, Fan;
Zhao, Huiyong;
Shao, Hong;
Marra, Antonio;
Patel, Payal;
O'Connell, Elizabeth;
Fink, Emma;
Miele, Matthew M.;
Li, Zhuoning;
De Stanchina, Elisa;
Cocco, Emiliano;
Razavi, Pedram;
Toska, Eneda;
Fanning, Sean W.;
Xu, Guotai;
Sablina, Anna A.;
Scaltriti, Maurizio;
Chandarlapaty, Sarat

Publication type:

Article

不同肿瘤中AKR1B10 的表达与作用.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 323, doi. 10.3872/j.issn.1007-385x.2025.03.013

By:

蒋堃;
综述;
曹德良;
吴萍;
审阅

Publication type:

Article

Response to a novel type II RAF inhibitor in diffuse leptomeningeal glioneuronal tumor with BRAF fusion.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf093

By:

Chun, Brie M;
Youngworth, Sandra;
Abtin, Vicki;
Stull, David;
Starkey, Jay;
Kummar, Shivaani

Publication type:

Article

Social jetlag elicits fatty liver via perturbed circulating prolactin rhythm-mediated circadian remodeling of hepatic lipid metabolism.

Published in:

Military Medical Research, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40779-025-00609-z

By:

Zhang, Peng-Zi;
Shi, Ying-Huan;
Guo, Yu-Xin;
Li, Ya-Yuan;
Yin, Hong-Li;
Wu, Tian-Yu;
Zhu, Ye;
Jiang, Jia-Xuan;
Bi, Yan

Publication type:

Article

Myocardial mitochondrial antiviral signaling protein promotes heart Ischemia-reperfusion injury via RIG-I signaling in mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60123-7

By:

Kang, Zhenyu;
Yang, Mengling;
Liu, Yue;
Gui, Yang;
Dong, Yalan;
Zhou, Haifeng;
Zhang, Zili;
Li, Mingyue;
Fan, Heng;
Li, Zheng;
Lu, Junjie;
Li, Junyi;
Zhu, Rui;
Yin, Chengyu;
Liu, Boyi;
Jiang, Feng;
Huang, Kun;
Sarapultsev, Alexey;
Li, Fangfei;
Zhang, Ge

Publication type:

Article

Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1555274

By:

Han, Lichao;
Ma, Yijia;
Wu, Weidong;
Ni, Qianyue;
Xie, Jingri;
Huang, Yan;
Jin, Qiuyu;
Wu, Lili;
Zhang, Yang

Publication type:

Article

Prunus persica Leaf Extract Mitigates Ultraviolet-Induced Skin Damage Via Activation of AMP-Activated Protein Kinase.

Published in:

Natural Product Communications, 2025, v. 20, n. 4, p. 1, doi. 10.1177/1934578X251330952

By:

Kim, Eun Ok;
Lee, Dae Geon;
Jung, Cheol Jong;
Yu, Yeong Eun;
Hong, Museok;
Cho, Il Je;
Ku, Sae Kwang

Publication type:

Article

Electroacupuncture attenuates middle cerebral artery occlusion-induced learning and memory impairment by regulating microglial polarization in hippocampus.

Published in:

International Journal of Neuroscience, 2025, v. 135, n. 6, p. 626, doi. 10.1080/00207454.2024.2313664

By:

Wen, Qiong;
Zha, Fubing;
Shan, Linlin;
Zhang, Shaohua;
Xiao, Peng;
Zhang, Chunxia;
Yu, Haibo;
Wang, Yulong

Publication type:

Article

Variation of the encoding hyaluronic receptors Hyaluronan-mediated motility receptor (rs299295) and Stabilin-2 (rs2271637) genes with prostate neoplasms risk: A case-control and in silico study.

Published in:

International Journal of Reproductive Biomedicine, 2025, v. 23, n. 3, p. 251, doi. 10.18502/ijrm.v23i3.18776

By:

Saleh Albdairi, Hayder Abdulhadi;
Colagar, Abasalt Hosseinzadeh

Publication type:

Article

Nootkatone Alleviates Type 2 Diabetes in db/db Mice Through AMPK Activation and ERK Inhibition: An Integrated In Vitro and In Vivo Study.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2111, doi. 10.3390/molecules30102111

By:

Li, Yingjie;
Zheng, Linlin;
Chen, Mimi;
Li, Ruodi;
Yu, Yansu;
Qiao, Lu;
Liu, Jialu;
Zhang, Xiaopo;
Zhang, Yong;
Zhang, Yuxin;
Zheng, Wei

Publication type:

Article

α-Mangostin Is a Xanthone Derivative from Mangosteen with Potent Immunomodulatory and Anti-Inflammatory Properties.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 681, doi. 10.3390/biom15050681

By:

Majdalawieh, Amin F.;
Khatib, Bayan K.;
Terro, Tala M.

Publication type:

Article

Fgf21 Deficiency Delays Hair Follicle Cycling and Modulates miRNA–Target Gene Interactions in Mice.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 526, doi. 10.3390/biology14050526

By:

Li, Yana;
Ao, Yue;
Xie, Xinru;
Ulan, Tug;
Liu, Dongjun;
Guo, Xudong

Publication type:

Article

The MEK5/ERK5 pathway promotes the activation of the Hedgehog/GLI signaling in melanoma cells.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 789, doi. 10.1007/s13402-025-01050-z

By:

Tusa, Ignazia;
Gagliardi, Sinforosa;
Menconi, Alessio;
Maresca, Luisa;
Tubita, Alessandro;
Lulli, Matteo;
Stecca, Barbara;
Rovida, Elisabetta

Publication type:

Article

Therapeutic Effect of Smilax glabra Roxb. on Weaning Rats Against Pb-Induced Nephrotoxicity Based on Network Pharmacology.

Published in:

Biological Trace Element Research, 2025, v. 203, n. 5, p. 2714, doi. 10.1007/s12011-024-04366-3

By:

Tian, Chongmei;
Yu, Meiting;
Fang, Yuejuan;
Zhao, Yaping;
Fu, Liping;
Chen, Jingbai;
Xia, Daozong

Publication type:

Article

Unveiling Oncogenic Power of WAVE1 in Bladder Cancer Progression.

Published in:

Biochemistry (00062979), 2025, v. 90, n. 4, p. 534, doi. 10.1134/S0006297924604489

By:

Cui, Shouxi;
Liang, Bin;
Liu, Yong

Publication type:

Article

一叶秋碱对人结肠癌 SW620 细胞增殖和凋亡的影响及其机制.

Published in:

Journal of Jilin University (Medicine Edition), 2025, v. 51, n. 2, p. 307, doi. 10.13481/j.1671⁃587X.20250204

By:

邓静;
王萱;
石长玉;
杨斯琦;
邹亲玲;
金明

Publication type:

Article

Antidiabetic GLP-1 Receptor Agonists Have Neuroprotective Properties in Experimental Animal Models of Alzheimer's Disease.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 614, doi. 10.3390/ph18050614

By:

Urkon, Melinda;
Ferencz, Elek;
Szász, József Attila;
Szabo, Monica Iudita Maria;
Orbán-Kis, Károly;
Szatmári, Szabolcs;
Nagy, Előd Ernő

Publication type:

Article

Comparative Transcriptome Analysis Elucidates the Desiccation Stress Adaptation in Sargassum muticum.

Published in:

Genes, 2025, v. 16, n. 5, p. 587, doi. 10.3390/genes16050587

By:

Cao, Wei;
Zhang, Mingyi;
Wu, Nan;
Zheng, Yanxin;
Li, Xiaodong;
Han, Haiying;
Yu, Tao;
Wu, Zhongxun;
Qu, Pei;
Li, Bo

Publication type:

Article

3,3′-Diindolylmethane Ameliorates Metabolism Dysfunction-Associated Fatty Liver Disease via AhR/p38 MAPK Signaling.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1681, doi. 10.3390/nu17101681

By:

Su, Jiewen;
Fang, Heng;
Lin, Yunfeng;
Yao, Yilu;
Liu, Yanxi;
Zhong, Yuquan;
Li, Xudong;
Sun, Siyu;
Huang, Bing;
Yang, Guangyu;
Li, Wenxue;
Zhang, Yan;
Li, Juntao;
Wu, Jinyin;
Liu, Weiwen;
Hu, Qiansheng;
Zhu, Wei

Publication type:

Article

Genome-Wide Identification, Phylogeny and Expressional Profiles of Mitogen Activated Protein Kinase Gene Family in Blakeslea trispora.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4789, doi. 10.3390/ijms26104789

By:

Ge, Xin;
Cui, Yue;
Zhang, Yanan;
Li, Jianlin;
Wang, Ping;
Zheng, Yan;
Xin, Qi

Publication type:

Article

Transcriptional Dynamics of Receptor-Based Genes Reveal Immunity Hubs in Rice Response to Magnaporthe oryzae Infection.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4618, doi. 10.3390/ijms26104618

By:

Salem, Fatma;
ElGamal, Ahmed;
Tang, Xiaoya;
Yang, Jianyuan;
Kong, Weiwen

Publication type:

Article

Zebrafish cdh23 Affects Rod Cell Phototransduction Through Regulating Ca 2+ Transport and MAPK Signaling Pathway.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4604, doi. 10.3390/ijms26104604

By:

Zheng, Xiaoying;
Xie, Binling;
Chen, Dingrui;
Jiang, Jifan;
Zeng, Ting;
Xiong, Lei;
Shi, Qingying;
Xie, Hao;
Cai, Yisheng;
Liang, Jiaxin;
Chen, Song;
Qu, Xiaochao;
Xie, Huaping

Publication type:

Article

LRR Receptor-like Protein in Rapeseed Confers Resistance to Sclerotinia sclerotiorum Infection via a Conserved Ss NEP2 Peptide.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4569, doi. 10.3390/ijms26104569

By:

Yang, Chenghuizi;
Zhong, Weiping;
Li, Wei;
Xia, Yunong;
Qin, Lei;
Tang, Xianyu;
Xia, Shitou

Publication type:

Article

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 22, p. 1, doi. 10.1002/adfm.202425394

By:

Dwivedy, Abhisek;
Baskaran, Dhyanesh;
Sharma, Gaurav;
Hong, Wei;
Gandavadi, Dhanush;
Krissanaprasit, Abhichart;
Han, Joonsu;
Liu, Yusheng;
Zimmers, Zack;
Mafokwane, Tshepo;
Hayah, Ichrak;
Chauhan, Neha;
Zheng, Mengxi;
Yao, Sherwood;
Fraser, Keith;
Decker, John S.;
Jin, Xiaohe;
Wang, Hua;
Friedman, Adam D.;
Wang, Xing

Publication type:

Article

MAPK信号通路在PCOS中的作用机制及中药单体的药理研究进展.

Published in:

Journal of International Obstetrics & Gynecology, 2024, v. 51, n. 6, p. 684, doi. 10.12280/gjfckx.20240713

By:

胡蝶;
任佳杰;
刘佳宁;
冯晓玲

Publication type:

Article

Allosteric enhancement of MAP kinase p38α's activity and substrate selectivity by docking interactions.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 704, doi. 10.1038/nsmb.2861

By:

Tokunaga, Yuji;
Takeuchi, Koh;
Takahashi, Hideo;
Shimada, Ichio

Publication type:

Article

Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 10, p. 1182, doi. 10.1038/nsmb.2668

By:

De Nicola, Gian Felice;
Martin, Eva Denise;
Chaikuad, Apirat;
Bassi, Rekha;
Clark, James;
Martino, Luigi;
Verma, Sharwari;
Sicard, Pierre;
Tata, Renée;
Atkinson, R Andrew;
Knapp, Stefan;
Conte, Maria R;
Marber, Michael S

Publication type:

Article

Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 5, p. 620, doi. 10.1038/nsmb.2557

By:

Suen, Kin Man;
Lin, Chi-Chuan;
George, Roger;
Melo, Fernando A;
Biggs, Eleanor R;
Ahmed, Zamal;
Drake, Melanie N;
Arur, Swathi;
Arold, Stefan T;
Ladbury, John E

Publication type:

Article

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 10, p. 1026, doi. 10.1038/nsmb.1656

By:

Kosako, Hidetaka;
Yamaguchi, Nozomi;
Aranami, Chizuru;
Ushiyama, Masato;
Kose, Shingo;
Imamoto, Naoko;
Taniguchi, Hisaaki;
Nishida, Eisuke;
Hattori, Seisuke

Publication type:

Article

PORE-ing over ERK substrates.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 10, p. 1004, doi. 10.1038/nsmb1009-1004

By:

Ahn, Natalie G.

Publication type:

Article

A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 3, p. 294, doi. 10.1038/nsmb.1564

By:

Catalanotti, Federica;
Reyes, Gloria;
Jesenberger, Veronika;
Galabova-Kovacs, Gergana;
de Matos Simoes, Ricardo;
Carugo, Oliviero;
Baccarini, Manuela

Publication type:

Article

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1150, doi. 10.1038/nsmb1316

By:

Rampalli, Shravanti;
LiFang Li;
Mak, Esther;
Kai Ge;
Brand, Marjorie;
Tapscott, Stephen J.;
Dilworth, F. Jeffrey

Publication type:

Article

Tumor necrosis factor and alzheimer's disease: a cause and consequence relationship.

Published in:

Klinik Psikofarmakoloji Bulteni, 2012, v. 22, n. 1, p. 86, doi. 10.5455/bcp.20120112064639

By:

Sharma, Vivek;
Thakur, Vinay;
Singh, Shesh Nath;
Guleria, Rajender

Publication type:

Article

Speak, friend, and enter: signalling systems that promote beneficial symbiotic associations in plants.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 4, p. 252, doi. 10.1038/nrmicro2990

By:

Oldroyd, Giles E. D.

Publication type:

Article

An epigenetic effector.

Published in:

Nature Reviews Microbiology, 2007, v. 5, n. 2, p. 87, doi. 10.1038/nrmicro1606

By:

Molloy, Sheilagh

Publication type:

Article

Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.

Published in:

2006

By:

Boyle, David L.;
Jones, Toni L.;
Hammaker, Deepa;
Svensson, Camille I.;
Rosengren, Sanna;
Albani, Salvatore;
Sorkin, Linda;
Firestein, Gary S.

Publication type:

journal article

The lncRNA LINC00339-encoded peptide promotes trophoblast adhesion to endometrial cells via MAPK and PI3K-Akt signaling pathways.

Published in:

Journal of Assisted Reproduction & Genetics, 2024, v. 41, n. 2, p. 493, doi. 10.1007/s10815-023-02995-6

By:

Zhou, Bo;
Yu, Guo;
Zhao, Mingqi;
Li, Yan;
Li, Jing;
Xiang, Yungai;
Tong, Lili;
Chu, Xiying;
Wang, Caiyi;
Song, Yuxia

Publication type:

Article

Wnt pathway modulation generates blastomere-derived mouse embryonic stem cells with different pluripotency features.

Published in:

Journal of Assisted Reproduction & Genetics, 2020, v. 37, n. 12, p. 2967, doi. 10.1007/s10815-020-01964-7

By:

Vila-Cejudo, Marta;
Alonso-Alonso, Sandra;
Pujol, Anna;
Santaló, Josep;
Ibáñez, Elena

Publication type:

Article

Oocyte maturation-related gene expression in the canine oviduct, cumulus cells, and oocytes and effect of co-culture with oviduct cells on in vitro maturation of oocytes.

Published in:

Journal of Assisted Reproduction & Genetics, 2017, v. 34, n. 7, p. 929, doi. 10.1007/s10815-017-0910-x

By:

Lee, Seok;
Oh, Hyun;
Kim, Min;
Kim, Geon;
Choi, Yoo;
Jo, Young;
Setyawan, Erif;
Lee, Byeong

Publication type:

Article

Effects of peroxiredoxin 1 on nicotine induced apoptosis in mouse tongue.

Published in:

Biotechnic & Histochemistry, 2020, v. 95, n. 8, p. 626, doi. 10.1080/10520295.2020.1749304

By:

Zhang, Min;
Wang, Chunxiao;
Chen, Hui;
Wang, Min;
Tang, Xiaofei

Publication type:

Article

Protective effects of taurine against renal ischemia/reperfusion injury in rats by inhibition of gelatinases, MMP-2 and MMP-9, and p38 mitogen-activated protein kinase signaling.

Published in:

Biotechnic & Histochemistry, 2017, v. 92, n. 7, p. 524, doi. 10.1080/10520295.2017.1367033

By:

Cavdar, Z;
Ural, C;
Celik, A;
Arslan, S;
Terzioglu, G;
Ozbal, S;
Yildiz, S;
Ergur, UB;
Guneli, E;
Camsari, T;
Akdogan, G

Publication type:

Article

Population Pharmacokinetics, Pharmacodynamics and Safety Properties of Trametinib in Dogs With Cancer: A Phase I Dose Escalating Clinical Trial.

Published in:

Veterinary & Comparative Oncology, 2024, v. 22, n. 3, p. 410, doi. 10.1111/vco.12989

By:

Takada, Marilia;
Kitagawa, Keita;
Zhang, Yongzhen;
Bulitta, Jürgen B.;
Moirano, Steven;
Jones, Abigail;
Borgen, Jennifer;
Onsager, Ashley;
Thaiwong, Tuddow;
Vail, David M.

Publication type:

Article