Works matching DE "NUCLEOTIDE synthesis"

Results: 333

SHMT inhibitor synergizes with 5-Fu to suppress gastric cancer via cell cycle arrest and chemoresistance alleviation.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00926-5

By:

Deng, Huan;
Wang, Yajie;
Xiao, Lin;
Feng, Mei;
Dou, Weidong;
Pan, Yisheng

Publication type:

Article

Mariculture Sludge Modifies Archaeal Community Diversity, Reduces Archaeal Variability, and Enhances Nitrogen Cycling Capacity in Paddy Soil.

Published in:

Water, Air & Soil Pollution, 2025, v. 236, n. 5, p. 1, doi. 10.1007/s11270-025-07906-2

By:

Pan, Junchi;
Li, Yajing;
Hu, Yuehang;
Qiu, Qiongfen

Publication type:

Article

Deep‐Ultraviolet Photoexcitation of Aqueous Urea Forms Carbamic Acid/Carbamate in Less Than One Picosecond.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 39, p. 1, doi. 10.1002/chem.202400728

By:

Thøgersen, Jan;
Madzharova, Fani;
Weidner, Tobias;
Jensen, Frank

Publication type:

Article

Site‐Specific Labeling of RNAs with Modified and <sup>19</sup>F‐Labeled Nucleotides by Chemo‐Enzymatic Synthesis.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 25, p. 1, doi. 10.1002/chem.202203368

By:

Sudakov, Alexey;
Knezic, Bozana;
Hengesbach, Martin;
Fürtig, Boris;
Stirnal, Elke;
Schwalbe, Harald

Publication type:

Article

Quantitation of non-amplified genomic DNA by bead-based hybridization and template mediated extension coupled to alkaline phosphatase signal amplification.

Published in:

Biotechnology Letters, 2010, v. 32, n. 2, p. 229, doi. 10.1007/s10529-009-0149-4

By:

Martins, S.;
Prazeres, D.;
Fonseca, L.;
Monteiro, G.

Publication type:

Article

Basic biochemical characterization of cytosolic enzymes in thymidine nucleotide synthesis in adult rat tissues: implications for tissue specific mitochondrial DNA depletion and deoxynucleoside-based therapy for TK2-deficiency.

Published in:

BMC Molecular & Cell Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12860-020-00272-3

By:

Wang, Liya;
Sun, Ren;
Eriksson, Staffan

Publication type:

Article

1,2,4‐Triazole benzamide derivative TPB against Gaeumannomyces graminis var. tritici as a novel dual‐target fungicide inhibiting ergosterol synthesis and adenine nucleotide transferase function.

Published in:

Pest Management Science, 2024, v. 80, n. 4, p. 1717, doi. 10.1002/ps.7900

By:

Wang, Limin;
Song, Xiaoyu;
Cheng, Yi‐nan;
Cheng, Senxiang;
Chen, Tong;
Li, Honglian;
Yan, Jingming;
Wang, Xiafei;
Zhou, Haifeng

Publication type:

Article

Targeted metabolomics reveals plasma biomarkers and metabolic alterations of the aging process in healthy young and older adults.

Published in:

GeroScience, 2023, v. 45, n. 6, p. 3131, doi. 10.1007/s11357-023-00823-4

By:

Jasbi, Paniz;
Nikolich-Žugich, Janko;
Patterson, Jeffrey;
Knox, Kenneth S.;
Jin, Yan;
Weinstock, George M.;
Smith, Patricia;
Twigg III, Homer L.;
Gu, Haiwei

Publication type:

Article

Nutrition of the arginine-family amino acids in nonruminant animals.

Published in:

Journal of Animal Science, 2006, v. 84, p. 257

By:

Wu, G.;
Kim, S. W.;
Knabe, D. A.;
Yin, Y. L.

Publication type:

Article

Metabolomic signatures of ideal cardiovascular health in black adults.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-51920-z

By:

Islam, Shabatun J.;
Liu, Chang;
Mohandas, Appesh N.;
Rooney, Kimberly;
Nayak, Aditi;
Mehta, Anurag;
Ko, Yi-An;
Kim, Jeong Hwan;
Sun, Yan V.;
Dunbar, Sandra B.;
Lewis, Tené T.;
Taylor, Herman A.;
Uppal, Karan;
Jones, Dean P.;
Quyyumi, Arshed A.;
Searles, Charles D.

Publication type:

Article

Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46572-6

By:

Ye, Minhui;
Fang, Yingzhe;
Chen, Lu;
Song, Zemin;
Bao, Qing;
Wang, Fei;
Huang, Hao;
Xu, Jin;
Wang, Ziwen;
Xiao, Ruijing;
Han, Meng;
Gao, Song;
Liu, Hudan;
Jiang, Baishan;
Qing, Guoliang

Publication type:

Article

Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46114-0

By:

Zarou, Martha M.;
Rattigan, Kevin M.;
Sarnello, Daniele;
Shokry, Engy;
Dawson, Amy;
Ianniciello, Angela;
Dunn, Karen;
Copland, Mhairi;
Sumpton, David;
Vazquez, Alexei;
Helgason, G. Vignir

Publication type:

Article

Hijacking of nucleotide biosynthesis and deamidation-mediated glycolysis by an oncogenic herpesvirus.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45852-5

By:

Wan, Quanyuan;
Tavakoli, Leah;
Wang, Ting-Yu;
Tucker, Andrew J.;
Zhou, Ruiting;
Liu, Qizhi;
Feng, Shu;
Choi, Dongwon;
He, Zhiheng;
Gack, Michaela U.;
Zhao, Jun

Publication type:

Article

Hijacking of nucleotide biosynthesis and deamidation-mediated glycolysis by an oncogenic herpesvirus.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45852-5

By:

Wan, Quanyuan;
Tavakoli, Leah;
Wang, Ting-Yu;
Tucker, Andrew J.;
Zhou, Ruiting;
Liu, Qizhi;
Feng, Shu;
Choi, Dongwon;
He, Zhiheng;
Gack, Michaela U.;
Zhao, Jun

Publication type:

Article

Amino acid catabolite markers for early prognostication of pneumonia in patients with COVID-19.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-44266-z

By:

Maeda, Rae;
Seki, Natsumi;
Uwamino, Yoshifumi;
Wakui, Masatoshi;
Nakagama, Yu;
Kido, Yasutoshi;
Sasai, Miwa;
Taira, Shu;
Toriu, Naoya;
Yamamoto, Masahiro;
Matsuura, Yoshiharu;
Uchiyama, Jun;
Yamaguchi, Genki;
Hirakawa, Makoto;
Kim, Yun-Gi;
Mishima, Masayo;
Yanagita, Motoko;
Suematsu, Makoto;
Sugiura, Yuki

Publication type:

Article

Process Development for the Enzymatic Gram‐Scale Production of the Unnatural Nucleotide Sugar UDP‐6‐Azido‐GalNAc.

Published in:

ChemSusChem, 2024, v. 17, n. 19, p. 1, doi. 10.1002/cssc.202400311

By:

Frohnmeyer, Hannes;
Verkade, Jorge M. M.;
Spiertz, Markus;
Rentsch, Andreas;
Hoffmann, Niels;
Sobota, Milan;
Schwede, Frank;
Tjeerdsma, Peter;
Elling, Lothar

Publication type:

Article

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.

Published in:

Biological Reviews, 2015, v. 90, n. 3, p. 927, doi. 10.1111/brv.12140

By:

Stincone, Anna;
Prigione, Alessandro;
Cramer, Thorsten;
Wamelink, Mirjam M. C.;
Campbell, Kate;
Cheung, Eric;
Olin‐Sandoval, Viridiana;
Grüning, Nana‐Maria;
Krüger, Antje;
Tauqeer Alam, Mohammad;
Keller, Markus A.;
Breitenbach, Michael;
Brindle, Kevin M.;
Rabinowitz, Joshua D.;
Ralser, Markus

Publication type:

Article

Culture-Independent Molecular Methods for Detection of Antifungal Resistance Mechanisms and Fungal Identification.

Published in:

2017

By:

Perlin, David S.;
Wiederhold, Nathan P.

Publication type:

journal article

Inconsistent diversities between nuclear and plastid genomes of AA genome species in the genus Oryza.

Published in:

Genes & Genetic Systems, 2015, v. 90, n. 5, p. 269, doi. 10.1266/ggs.14-00063

By:

Hao Yin;
Masahiro Akimoto;
Kaewcheenchai, Reunreudee;
Masahiro Sotowa;
Takashige Ishii;
Ryuji Ishikawa

Publication type:

Article

Adaptation insights from comparative transcriptome analysis of two Opisthopappus species in the Taihang mountains.

Published in:

BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08703-5

By:

Chen, Ning;
Zhang, Hao;
Zang, En;
Liu, Zhi-Xia;
Lan, Ya-Fei;
Hao, Wei-Li;
He, Shan;
Fan, Xing;
Sun, Gen-Lou;
Wang, Yi-Ling

Publication type:

Article

Systematic characterization of pan-cancer mutation clusters.

Published in:

Molecular Systems Biology, 2018, v. 14, n. 3, p. 1, doi. 10.15252/msb.20177974

By:

Buljan, Marija;
Blattmann, Peter;
Aebersold, Ruedi;
Boutros, Michael

Publication type:

Article

Metabolic flexibilities and vulnerabilities in the pentose phosphate pathway of the zoonotic pathogen Toxoplasma gondii.

Published in:

PLoS Pathogens, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.ppat.1010864

By:

Xia, Ningbo;
Guo, Xuefang;
Guo, Qinghong;
Gupta, Nishith;
Ji, Nuo;
Shen, Bang;
Xiao, Lihua;
Feng, Yaoyu

Publication type:

Article

Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes.

Published in:

PLoS Pathogens, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.ppat.1010743

By:

Yang, Emily;
Huang, Serina;
Jami-Alahmadi, Yasaman;
McInerney, Gerald M.;
Wohlschlegel, James A.;
Li, Melody M. H.

Publication type:

Article

High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival.

Published in:

PLoS Genetics, 2018, v. 14, n. 4, p. 1, doi. 10.1371/journal.pgen.1007301

By:

Rubin, Benjamin E.;
Huynh, TuAnh Ngoc;
Welkie, David G.;
Diamond, Spencer;
Simkovsky, Ryan;
Pierce, Emily C.;
Taton, Arnaud;
Lowe, Laura C.;
Lee, Jenny J.;
Rifkin, Scott A.;
Woodward, Joshua J.;
Golden, Susan S.

Publication type:

Article

Improving Mycoplasma ovipneumoniae culture medium by a comparative transcriptome method.

Published in:

Journal of Veterinary Science, 2020, v. 21, n. 2, p. 1, doi. 10.4142/jvs.2020.21.e30

By:

Xiaohui Wang;
Wenguang Zhang;
Yongqing Hao

Publication type:

Article

Synthesis of nucleotide analogues, EFdA, EdA and EdAP, and the effect of EdAP on hepatitis B virus replication.

Published in:

Bioscience, Biotechnology & Biochemistry, 2020, v. 84, n. 2, p. 217, doi. 10.1080/09168451.2019.1673696

By:

Kamata, Mai;
Takeuchi, Toshifumi;
Hayashi, Ei;
Nishioka, Kazane;
Oshima, Mizuki;
Iwamoto, Masashi;
Nishiuchi, Kota;
Kamo, Shogo;
Tomoshige, Shusuke;
Watashi, Koichi;
Kamisuki, Shinji;
Ohrui, Hiroshi;
Sugawara, Fumio;
Kuramochi, Kouji

Publication type:

Article

Mixed-phase weak anion-exchange/reversed-phase LC–MS/MS for analysis of nucleotide sugars in human fibroblasts.

Published in:

Analytical & Bioanalytical Chemistry, 2024, v. 416, n. 15, p. 3595, doi. 10.1007/s00216-024-05313-w

By:

Rahm, Moritz;
Kwast, Hanneke;
Wessels, Hans J. C. T.;
Noga, Marek J.;
Lefeber, Dirk J.

Publication type:

Article

Prebiotic N-(2-Aminoethyl)-Glycine (AEG)-Assisted Synthesis of Proto-RNA?

Published in:

Journal of Molecular Evolution, 2024, v. 92, n. 4, p. 449, doi. 10.1007/s00239-024-10185-w

By:

Castanedo, Lázaro A. M.;
Matta, Chérif F.

Publication type:

Article

Nucleobases in Meteorites to Nucleobases in RNA and DNA?

Published in:

Journal of Molecular Evolution, 2022, v. 90, n. 5, p. 328, doi. 10.1007/s00239-022-10069-x

By:

Krishnamurthy, Ramanarayanan;
Goldman, Aaron D.;
Liberles, David A.;
Rogers, Karyn L.;
Tor, Yitzhak

Publication type:

Article

WHITE STRIPE LEAF8, encoding a deoxyribonucleoside kinase, is involved in chloroplast development in rice.

Published in:

Plant Cell Reports, 2020, v. 39, n. 1, p. 19, doi. 10.1007/s00299-019-02470-6

By:

Liu, L. L.;
You, J.;
Zhu, Z.;
Chen, K. Y.;
Hu, M. M.;
Gu, H.;
Liu, Z. W.;
Wang, Z. Y.;
Wang, Y. H.;
Liu, S. J.;
Chen, L. M.;
Liu, X.;
Tian, Y. L.;
Zhou, S. R.;
Jiang, L.;
Wan, J. M.

Publication type:

Article

Antitumor Mechanism of Hydroxycamptothecin via the Metabolic Perturbation of Ribonucleotide and Deoxyribonucleotide in Human Colorectal Carcinoma Cells.

Published in:

Molecules, 2021, v. 26, n. 16, p. 4902, doi. 10.3390/molecules26164902

By:

Li, Yan;
Luo, Wendi;
Zhang, Huixia;
Wang, Caiyun;
Yu, Caiyuan;
Jiang, Zhihong;
Zhang, Wei

Publication type:

Article

Nucleotide Sugars in Chemistry and Biology.

Published in:

Molecules, 2020, v. 25, n. 23, p. 5755, doi. 10.3390/molecules25235755

By:

Mikkola, Satu;
Hodgson, David R. W.

Publication type:

Article

Evaluation of Bronopol and Disulfiram as Potential Candidatus Liberibacter asiaticus Inosine 5′-Monophosphate Dehydrogenase Inhibitors by Using Molecular Docking and Enzyme Kinetic.

Published in:

Molecules, 2020, v. 25, n. 10, p. 2313, doi. 10.3390/molecules25102313

By:

Nan, Jing;
Zhang, Shaoran;
Zhan, Ping;
Jiang, Ling

Publication type:

Article

Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair.

Published in:

Molecules, 2020, v. 25, n. 5, p. 1205, doi. 10.3390/molecules25051205

By:

Miggiano, Riccardo;
Morrone, Castrese;
Rossi, Franca;
Rizzi, Menico;
Chiarelli, Laurent

Publication type:

Article

Isolation, Characterization and Bioactivities of an Extracellular Polysaccharide Produced from Streptomyces sp. MOE6.

Published in:

Molecules, 2017, v. 22, n. 9, p. 1396, doi. 10.3390/molecules22091396

By:

Elnahas, Marwa O.;
Amin, Magdy A.;
Hussein, Mohamed M. D.;
Shanbhag, Vinit C.;
Ali, Amal E.;
Wall, Judy D.

Publication type:

Article

Modified Nucleotides as Substrates of Terminal Deoxynucleotidyl Transferase.

Published in:

Molecules, 2017, v. 22, n. 4, p. 672, doi. 10.3390/molecules22040672

By:

Tauraitė, Daiva;
Jakubovska, Jevgenija;
Dabužinskaitė, Julija;
Bratchikov, Maksim;
Meškys, Rolandas

Publication type:

Article

Nuclear NAD<sup>+</sup>-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.71185

By:

Sokolov, David;
Sechrest, Emily R.;
Yekai Wang;
Nevin, Connor;
Jianhai Du;
Kolandaivelu, Saravanan

Publication type:

Article

3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation.

Published in:

Cancer & Metabolism, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40170-021-00273-6

By:

Skaripa-Koukelli, Irini;
Hauton, David;
Walsby-Tickle, John;
Thomas, Eloïse;
Owen, Joshua;
Lakshminarayanan, Abirami;
Able, Sarah;
McCullagh, James;
Carlisle, Robert C.;
Vallis, Katherine A.

Publication type:

Article

Editorial Comment to "Causal relationship between folic acid and prostate cancer risk: Insights from Mendelian randomization analysis".

Published in:

International Journal of Urology, 2024, v. 31, n. 12, p. 1364, doi. 10.1111/iju.15582

By:

Mitsui, Yozo;
Nakajima, Koichi

Publication type:

Article

CpG-ODN induced antimicrobial immunity in neonatal chicks involves a substantial shift in serum metabolic profiles.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88386-2

By:

Goonewardene, Kalhari Bandara;
Karu, Naama;
Ahmed, Khawaja Ashfaque;
Popowich, Shelly;
Chow-Lockerbie, Betty;
Ayalew, Lisanework E.;
Karunarathna, Ruwani;
Gunawardana, Thushari;
Liu, Mengying;
Tikoo, Suresh K.;
Foldvari, Marianna;
Willson, Philip;
Mandal, Rupasri;
Wishart, David S.;
Gomis, Susantha

Publication type:

Article

Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68130-y

By:

Jain, Ruchi;
Özgümüş, Türküler;
Jensen, Troels Mygind;
du Plessis, Elsa;
Keindl, Magdalena;
Møller, Cathrine Laustrup;
Falhammar, Henrik;
Nyström, Thomas;
Catrina, Sergiu-Bogdan;
Jörneskog, Gun;
Jessen, Leon Eyrich;
Forsblom, Carol;
Haukka, Jani K.;
Groop, Per-Henrik;
Rossing, Peter;
Groop, Leif;
Eliasson, Mats;
Eliasson, Björn;
Brismar, Kerstin;
Al-Majdoub, Mahmoud

Publication type:

Article

Overexpression of Phosphoribosyl Pyrophosphate Synthase Enhances Resistance of Chlamydomonas to Ionizing Radiation.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.719846

By:

Jung, Sera;
Koo, Kwang Min;
Ryu, Jaihyunk;
Baek, Inwoo;
Kwon, Soon-Jae;
Kim, Jin-Baek;
Ahn, Joon-Woo

Publication type:

Article

CTP Synthase 2 From Arabidopsis thaliana Is Required for Complete Embryo Development.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. N.PAG, doi. 10.3389/fpls.2021.652434

By:

Hickl, Daniel;
Scheuring, David;
Möhlmann, Torsten

Publication type:

Article

Pyrimidine metabolism regulator-mediated molecular subtypes display tumor microenvironmental hallmarks and assist precision treatment in bladder cancer.

Published in:

Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1102518

By:

Zixuan Wu;
Xiaohuan Li;
Zhenchang Gu;
Xinhua Xia;
Jing Yang

Publication type:

Article

NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.989263

By:

Guohang Xiong;
Yu Feng;
Xiaojia Yi;
Xuedan Zhang;
Xiaoyu Li;
Lijuan Yang;
Zihan Yi;
Buqing Sai;
Zhe Yang;
Qiao Zhang;
Yingmin Kuang;
Yuechun Zhu

Publication type:

Article

Diagnostic and prognostic value of thymidylate synthase expression in breast cancer.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2021, v. 48, n. 2, p. 279, doi. 10.1111/1440-1681.13415

By:

Song, Shaoran;
Tian, Bixia;
Zhang, Miao;
Gao, Xiaoqian;
Jie, Liu;
Liu, Peijun;
Li, Juan

Publication type:

Article

Metabolic changes induced by DNA damage in Ramos cells: exploring the role of mTORC1 complex.

Published in:

FEBS Open Bio, 2022, v. 12, n. 8, p. 1509, doi. 10.1002/2211-5463.13436

By:

Castro-Guarda, Marcos;
Arancibia, Yennyfer;
Chipón, Carina;
Matamala, Christofer;
Oyarzo, Paola;
Vargas, Gabriela;
Reyes, Alejandro;
Salas, Mónica;
Morera, Francisco J.;
Zambrano, Angara

Publication type:

Article

Guaiazulene derivative 1,2,3,4‐tetrahydroazuleno[1,2‐b] tropone reduces the production of ATP by inhibiting electron transfer complex II.

Published in:

FEBS Open Bio, 2021, v. 11, n. 11, p. 2921, doi. 10.1002/2211-5463.13215

By:

Kasami, Chieko;
Yamaguchi, Jun‐ichi;
Inoue, Hideki

Publication type:

Article

What can asymmetrical cell snakes do?

Published in:

BioEssays, 2022, v. 44, n. 12, p. 1, doi. 10.1002/bies.202200193

By:

Chang, Chia‐Chun;
Liu, Ji‐Long

Publication type:

Article

Identification of a Novel Aflatoxin B 1 -Degrading Strain, Bacillus halotolerans DDC-4, and Its Response Mechanisms to Aflatoxin B 1.

Published in:

Toxins, 2024, v. 16, n. 6, p. 256, doi. 10.3390/toxins16060256

By:

Guo, Jia;
Zhang, Hanlu;
Zhao, Yixuan;
Hao, Xiaoxu;
Liu, Yu;
Li, Suhong;
Wu, Rina

Publication type:

Article