Works matching DE "SMALL molecules"

Results: 5000

Comparison of urea clearance in low-efficiency low-flux vs. high-efficiency high-flux dialyzer membrane with reduced blood and dialysate flow: An in vitro analysis.

Published in:

Hemodialysis International, 2014, v. 18, n. 1, p. 172, doi. 10.1111/hdi.12054

By:

Munshi, Raj;
Ahmad, Suhail

Publication type:

Article

Tumor immune remodeling by TGFβ inhibition improves the efficacy of radiation therapy.

Published in:

OncoImmunology, 2015, v. 4, n. 3, p. 00, doi. 10.4161/21624011.2014.955696

By:

Young, Kristina H;
Gough, Michael J;
Crittenden, Marka

Publication type:

Article

Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells.

Published in:

OncoImmunology, 2014, v. 3, n. 4, p. N.PAG, doi. 10.4161/onci.28541

By:

Beug, Shawn T;
LaCasse, Eric C;
Korneluk, Robert G

Publication type:

Article

Evolution of Eligibility Criteria in Inflammatory Bowel Disease Clinical Trials: A Clinical Trial Databank Analysis.

Published in:

United European Gastroenterology Journal, 2025, v. 13, n. 4, p. 542, doi. 10.1002/ueg2.12731

By:

Outtier, An;
Janssens, Rosanne;
Barbier, Liese;
Sabino, João;
Verstockt, Bram;
Vermeire, Séverine;
Huys, Isabelle;
Ferrante, Marc

Publication type:

Article

Multi‐Omics Biomarkers for Predicting Efficacy of Biologic and Small‐Molecule Therapies in Adults With Inflammatory Bowel Disease: A Systematic Review.

Published in:

2025

By:

Chen, Liru;
Zhang, Chuhan;
Niu, Ruixuan;
Xiong, Shanshan;
He, Jinshen;
Wang, Yu;
Zhang, Pingxin;
Su, Fengyuan;
Liu, Zishan;
Zhou, Longyuan;
Mao, Ren;
Hu, Shixian;
Chen, Minhu;
Qiu, Yun;
Feng, Rui

Publication type:

Literature Review

Using Extracellular miRNA Signatures to Identify Patients with LRRK2-Related Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2024, v. 14, n. 5, p. 977, doi. 10.3233/JPD-230408

By:

Braunger, Luca Jannik;
Knab, Felix;
Gasser, Thomas

Publication type:

Article

The Compound ATH434 Prevents Alpha-Synuclein Toxicity in a Murine Model of Multiple System Atrophy.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 1, p. 105, doi. 10.3233/JPD-212877

By:

Finkelstein, David I.;
Shukla, Jay J.;
Cherny, Robert A.;
Billings, Jessica L.;
Saleh, Eiman;
Stefanova, Nadia;
Barnham, Kevin J.;
Adlard, Paul A.

Publication type:

Article

Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats.

Published in:

Journal of Parkinson's Disease, 2021, v. 11, n. 3, p. 1023, doi. 10.3233/JPD-202400

By:

Renko, Juho-Matti;
Mahato, Arun Kumar;
Visnapuu, Tanel;
Valkonen, Konsta;
Karelson, Mati;
Voutilainen, Merja H.;
Saarma, Mart;
Tuominen, Raimo K.;
Sidorova, Yulia A.

Publication type:

Article

Exosomes as nanocarriers for brain-targeted delivery of therapeutic nucleic acids: advances and challenges.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03528-2

By:

Sanadgol, Nima;
Abedi, Mohsen;
Hashemzaei, Masoud;
Kamran, Zahra;
Khalseh, Roghayeh;
Beyer, Cordian;
Voelz, Clara

Publication type:

Article

Achieving High Fill Factor via Increasing Interfacial Disorder to Inhibit Bimolecular Recombination for Efficient Organic Solar Cells.

Published in:

Angewandte Chemie, 2025, v. 137, n. 25, p. 1, doi. 10.1002/ange.202505722

By:

He, Dan;
Xie, Linwei;
Bai, Yahui;
Zhang, Huotian;
Liu, Liping;
Kong, Jingyao;
Chai, Yongqiang;
Li, Xiaojun;
Wang, Mengni;
Zhang, Yajie;
Zhang, Jianqi;
Li, Yongfang;
Gao, Feng;
Guldi, Dirk M.;
Zhao, Fuwen

Publication type:

Article

MS1FA: Shiny app for the annotation of redundant features in untargeted metabolomics datasets Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 5, p. 1, doi. 10.1093/bioinformatics/btaf161

By:

Shi, Ruibing;
Klawonn, Frank;
Brönstrup, Mark;
Franke, Raimo

Publication type:

Article

Identification of compounds to promote diabetic wound healing based on transcriptome signature.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1576056

By:

Shang, Jiamin;
Liu, Zhaoyu;
Liang, Meidai;
Yin, Zijie;
Yang, Zeyu;
Ye, Xiaomeng;
Du, Guanhua;
Yang, Xiuying

Publication type:

Article

Drug repositioning for pan-cancers of the digestive system: Identification of amonafide and BX795 as potential therapeutics via integrative Omics analysis.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325700

By:

Liu, Weidong;
Gao, Jiaying;
Ren, Shuqiang;
Nashun, Buhe;
Gao, Fei

Publication type:

Article

Leucine-rich repeat kinase 2 biomarkers for Parkinson's disease.

Published in:

Biochemical Journal, 2025, v. 482, n. 11, p. 709, doi. 10.1042/BCJ20253099

By:

Dzamko, Nicolas

Publication type:

Article

Pan-cancer analysis of TMED2: unraveling potential immune characteristics and prognostic value in cancer therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1578627

By:

Wang, Zhuangzhi;
Sun, Changning;
Wang, Pengfei;
Lin, Shouyang;
Wu, Xiao;
Gu, Yuchao

Publication type:

Article

Drug repurposing of fostamatinib against cancer via potential cytotoxicity and immune checkpoint regulation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1602189

By:

Hu, Maoqiong;
Yin, Renyi;
Deng, Kaifeng;
Xu, Ning

Publication type:

Article

c-di-GMP does not bind H-NS, nor inhibits H-NS binding DNA.

Published in:

2025

By:

Wang, Jiayu;
Wei, Hehan;
Xia, Bin

Publication type:

Letter

Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01574-3

By:

Kim, Yeojin;
Lučić, Aleksandar;
Lenz, Christopher;
Farges, Frederic;
Schwalm, Martin P.;
Saxena, Krishna;
Hanke, Thomas;
Marples, Peter G.;
Aschenbrenner, Jasmin C.;
Fearon, Daren;
von Delft, Frank;
Krämer, Andreas;
Knapp, Stefan

Publication type:

Article

两亲性氮杂氟化硼二吡咯组装体用于光热抗菌.

Published in:

Journal of Functional Polymers, 2025, v. 38, n. 3, p. 245, doi. 10.14133/j.cnki.1008-9357.20240507001

By:

赵泽人;
刘鑫;
郑斌

Publication type:

Article

Elucidating the DNA binder interaction: a spectroscopic and computational study of fuchsine basic and salicylic hydroxamic acid.

Published in:

Journal of the Iranian Chemical Society, 2025, v. 22, n. 6, p. 1291, doi. 10.1007/s13738-025-03226-8

By:

AL-Azzawi, Ammar M. K.;
Hassan, Ekhlas Abdallah;
Ali, Wassan Baqir

Publication type:

Article

ONECUT2 reprograms neuroendocrine fate and is an actionable therapeutic target in small cell lung cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01267-6

By:

Gutiérrez, Mirian;
Zamora, Irene;
Iriarte, Raquel;
Pajares, María José;
Yang, Qian;
Qian, Chen;
Otegui, Nerea;
Fernández-Irigoyen, Joaquín;
Santamaría, Enrique;
Alcala, Nicolas;
Sexton-Oates, Alexandra;
Fernández-Cuesta, Lynnette;
Barajas, Miguel;
Calvo, Alfonso;
Montuenga, Luis M.;
Knudsen, Beatrice;
You, Sungyong;
Freeman, Michael R.;
Encío, Ignacio;
Rotinen, Mirja

Publication type:

Article

The Era of Precision Medicine: Advancing Treatment Paradigms for Small Cell Lung Cancer.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1847, doi. 10.3390/cancers17111847

By:

Corica, Derek A.;
Bell, Scott D.;
Zhao, Lei;
Lawler, Nicholas J.;
Poirier, McKade A.;
Miller, Peyton J.;
Wakefield, Mark R.;
Fang, Yujiang

Publication type:

Article

Plant–Fungi Mutualism, Alternative Splicing, and Defense Responses: Balancing Symbiosis and Immunity.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5197, doi. 10.3390/ijms26115197

By:

Zhao, Xiaoqiong;
Muhammad Aslam, Mehtab;
Chen, Moxian;
Das, Debatosh

Publication type:

Article

Hyaluronan: An Architect and Integrator for Cancer and Neural Diseases.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5132, doi. 10.3390/ijms26115132

By:

Hsu, Che-Yu;
Nguyen-Tran, Hieu-Huy;
Chen, Yu-An;
Lee, Kuan-Ting;
Juang, Tzong-Yuan;
Chiang, Ming-Fu;
Liu, Shin-Yi;
Chang, Nan-Shan

Publication type:

Article

Protective Effect of a Hexapeptide Derived from Rotifer-Specific SCO-Spondin Against Beta-Amyloid Toxicity.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5109, doi. 10.3390/ijms26115109

By:

Datki, Zsolt;
Sinka, Rita;
Dingmann, Brian J.;
Galik, Bence;
Szabo, Antal;
Galik-Olah, Zita;
Toth, Gabor K.;
Bozso, Zsolt

Publication type:

Article

Optimizing the Size of Zr-Based Metal–Organic Frameworks for Enhanced Anticancer Efficacy.

Published in:

Nanomaterials (2079-4991), 2025, v. 15, n. 11, p. 826, doi. 10.3390/nano15110826

By:

Cheng, Zan;
Yu, Mei;
Wan, Yilong;
Xiang, Huandong;
Wei, Haoran;
Zu, Xu;
Li, Xin;
Zhang, Ruiting;
Li, Fangshu;
Wang, Shanshan;
She, Yongxin

Publication type:

Article

Efficient Generation of Induced Pluripotent Stem Cell-Derived Definitive Endoderm Cells with Growth Factors and Small Molecules.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 815, doi. 10.3390/cells14110815

By:

Asumda, Faizal Z.;
Alzoubi, Shadia;
Padarath, Kiyasha;
John, Nina;
Jones, Kimya;
Kolhe, Ravindra;
Mondal, Ashis Kumar;
Lee, Tae Jin;
Zhi, Wenbo;
Huebert, Robert C.;
Staff, Nathan P.;
Kirkeby, Lindsey A.

Publication type:

Article

N-Alkylamino Stilbene Compounds as Amyloid β Inhibitors for Alzheimer's Disease Research.

Published in:

Molecules, 2025, v. 30, n. 11, p. 2471, doi. 10.3390/molecules30112471

By:

Gutiérrez, Citlali;
Sun, Liang;
Huang, Yiran;
Gui, Kai;
Terpstra, Karna;
Mirica, Liviu M.

Publication type:

Article

Recent Advances in the Development of Functional Nucleic Acid Biosensors Based on Aptamer-Rolling Circle Amplification.

Published in:

Molecules, 2025, v. 30, n. 11, p. 2375, doi. 10.3390/molecules30112375

By:

Liu, Ce;
He, Wanchong

Publication type:

Article

Recent Advances in Calix[4]arene‐Catalyzed Synthesis of Five‐ and Six‐Membered Oxa‐ and Azacycles.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 15, p. 1, doi. 10.1002/ejoc.202401461

By:

Wang, Meiling;
Li, Tao;
Shi, Jing;
Sun, Xiaoqiang;
Yang, Ke;
Li, Zheng‐Yi

Publication type:

Article

Synthesis and Functionalization of Aziridines: A Perspective View from Pharmaceutical Industries.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 15, p. 1, doi. 10.1002/ejoc.202401414

By:

Ju, Xuan;
Lee, Miseon;
Leung, Joyce C.;
Lee, Jaehee

Publication type:

Article

Targeting the Inactive Conformation of the Epidermal Growth Factor Receptor Identifies EG31: A Novel Small Molecule Inhibitor Effective Against Normal and 5-Fluorouracil-Resistant Triple Negative Breast Cancer Cells.

Published in:

OncoTargets & Therapy, 2025, v. 18, p. 617, doi. 10.2147/OTT.S512184

By:

Otifi, Hassan M

Publication type:

Article

Self‐assembled free nanocarrier prodrugs based on camptothecin and dihydroartemisinin exhibit accumulation and improved anticancer efficacy.

Published in:

Biotechnology & Applied Biochemistry, 2025, v. 72, n. 3, p. 793, doi. 10.1002/bab.2698

By:

Garg, Mohan;
Rangaswamy, Roopashree;
Mishra, Rahul;
Giri, Shivangi;
Chinnathambi, Arunachalam;
Alahmadi, Tahani Awad;
Arulselvan, Palanisamy;
Thangavelu, Indumathi

Publication type:

Article

"Regression to the truth": lessons learned from negative IPF trials.

Published in:

Breathe, 2025, v. 21, n. 2, p. 1, doi. 10.1183/20734735.0260-2024

By:

Trachalaki, Athina;
Lindahl, Anna L.;
Petrarulo, Simone;
Margaritopoulos, George A.

Publication type:

Article

Front Cover: Stabilities and Limitations in the Reactivity of Phosphorus Ylide‐Based Aluminum– and Gallium–Carbon Ambiphiles: A Combined Experimental and Computational Approach (Eur. J. Inorg. Chem. 16/2025).

Published in:

European Journal of Inorganic Chemistry, 2025, v. 28, n. 16, p. 1, doi. 10.1002/ejic.202581601

By:

Krämer, Felix;
Weisenburger, Pascal;
Fernández, Israel;
Breher, Frank

Publication type:

Article

Combining Low‐Valent Al<sup>I</sup> and Sn<sup>II</sup> Metal Centers for Small Molecule Activation.

Published in:

European Journal of Inorganic Chemistry, 2025, v. 28, n. 16, p. 1, doi. 10.1002/ejic.202500050

By:

Löwl, Tristan;
Maurer, Johannes;
Roig, Nil;
Mai, Jonathan;
Langer, Jens;
Alonso, Mercedes;
Harder, Sjoerd

Publication type:

Article

Solventless Dual‐Cure Liquid Resins Via Circular Use of Phthalic Anhydride for Recyclable Composite Applications.

Published in:

Macromolecular Rapid Communications, 2025, v. 46, n. 11, p. 1, doi. 10.1002/marc.202400909

By:

Musgrave, Grant M.;
Reese, Caleb J.;
Kirk, Tyler A.;
Wang, Chen

Publication type:

Article

Neuroprotection induced by protease-activated receptor 2 activation is independent of Gq signalling.

Published in:

Brain & Neuroscience Advances, 2025, p. 1, doi. 10.1177/23982128251345673

By:

Moudio, Serge;
Nuthall, Hugh N.;
Bushell, Trevor J.

Publication type:

Article

Differentially expressed genes in Huh7 cells during coculture with LX2 cells demonstrating dynamics of intercellular communication.

Published in:

Annals of Hepatology: Official Journal of the Mexican Association of Hepatology, 2025, v. 30, n. 1, p. 1, doi. 10.1016/j.aohep.2024.101746

By:

Heredia-Torres, Tania G.;
Alvarado-Martínez, Veronica;
Rincón-Sánchez, Ana R.;
Lozano-Sepúlveda, Sonia A.;
Galán-Huerta, Kame A.;
Arellanos-Soto, Daniel;
Rivas-Estilla, Ana M.

Publication type:

Article

A REVIEW OF STRUCTURAL FEATURES IN NOVEL MOLECULES EVALUATED FOR ANTITUBERCULAR ACTIVITY.

Published in:

Indian Drugs, 2025, v. 62, n. 5, p. 7, doi. 10.53879/id.62.05.14904

By:

Chaskara, Pratip K.;
Somani, Rakesh R.

Publication type:

Article

Data-driven discovery of chemical signatures for developing new inhibitors against human influenza viruses.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01540-z

By:

Kharatyan, Levon;
Gevorgyan, Smbat;
Khachatryan, Hamlet;
Shavina, Anastasiya;
Hakobyan, Astghik;
Matevosyan, Mher;
Zakaryan, Hovakim

Publication type:

Article

Immunotherapies versus small-molecule therapies of cancers with RAS oncogene mutations.

Published in:

Polish Journal of Allergology / Alergologia Polska, 2025, v. 12, n. 2, p. 111, doi. 10.5114/pja.2025.148075

By:

Rieske, Piotr

Publication type:

Article

KIFC1 inhibition: Exploring the potential of propolis-derived small molecules for targeting cancer progression through in silico analysis.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0324678

By:

Azmi, Muhammad Bilal;
Kumari, Simran;
Aquil, Sakina;
Nizami, Urooj;
Sohail, Arisha;
Ahmed, Syed Danish Haseen;
Qureshi, Shamim Akhtar

Publication type:

Article

Exploring the Adsorption Features of Furan and 1,n‐Dioxane as Environmental Toxins on Two‐Dimensional RuC Nanosheet: A DFT Study.

Published in:

ChemistryOpen, 2025, v. 14, n. 6, p. 1, doi. 10.1002/open.202400415

By:

Mahmoud, Amna H. M.;
Aziz, Muhrail E. S.;
Rabee, Abdallah I. M.;
El‐Tayeb, Mohamed A.;
Mekhemer, Gamal A. H.;
Shoeib, Tamer;
Ibrahim, Mahmoud A. A.

Publication type:

Article

Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534989

By:

Jordan, Maria;
Schmidt, Kevin;
Fuchs, Maximilian;
Just, Annette;
Pfanne, Angelika;
Willmer, Lena;
Neubert, Lavinia;
Werlein, Christopher;
Zardo, Patrick;
Pich, Andreas;
Thum, Thomas;
Fiedler, Jan

Publication type:

Article

Machine learning-driven identification of exosome- related biomarkers in head and neck squamous cell carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1590331

By:

He, Yaodong;
Li, Yun;
Tang, Jiaqi;
Wang, Yan;
Zhao, Zhenyan;
Liu, Rong;
Yang, Zihui;
Li, Huan;
Wei, Jianhua

Publication type:

Article

Casein kinase 1 epsilon (CK1ε) as a potential therapeutic target in chronic liver disease.

Published in:

Journal of Veterinary Science, 2025, v. 26, n. 3, p. 1, doi. 10.4142/jvs.24321

By:

Leya, Mwense;
Thach Phan Van;
Jong-Won Kim;
Bumseok Kim

Publication type:

Article

Over 19.2% Efficiency of Layer‐By‐Layer Organic Photovoltaics by Ameliorating Exciton Dissociation and Charge Transport.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 23, p. 1, doi. 10.1002/adfm.202422867

By:

Tian, Hongyue;
Zhou, Hang;
Zhang, Lu;
Xu, Wenjing;
Gong, Ruifeng;
Ni, Yuheng;
Jeong, Sang Young;
Zhu, Xixiang;
Woo, Han Young;
Ma, Xiaoling;
Lu, Lifang;
Zhang, Fujun

Publication type:

Article

ELF1-mediated transactivation of METTL3/YTHDF2 promotes nucleus pulposus cell senescence via m6A-dependent destabilization of E2F3 mRNA in intervertebral disc degeneration.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02515-8

By:

Liu, Xiao-Wei;
Xu, Hao-Wei;
Zhang, Shu-Bao;
Yi, Yu-Yang;
Chang, Sheng-Jie;
Wang, Shan-Jin

Publication type:

Article

三维电解-Fenton 法处理垃圾膜浓缩液试验.

Published in:

Journal of Guilin University of Technology, 2025, v. 45, n. 1, p. 95, doi. 10.3969/j.issn.1674-9057.2025.01.011

By:

王潇潇;
钟溢健;
李金城;
陆祖贤;
罗雪静;
朱红祥

Publication type:

Article