Works matching DE "P-glycoprotein"

Results: 2452

Population pharmacokinetic analysis of rivaroxaban in healthy volunteers and patients with radiofrequency ablation of non-valvular atrial fibrillation in China.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1562259

By:

Gu, Fangfang;
Tang, Kaixian;
Zhang, Cong;
Hu, Mingsheng;
Sun, Junlong;
Yu, Xiang;
Tian, Mengli;
Zhang, Chen;
Chen, Yingrong

Publication type:

Article

A Systematic Review and Classification of the Effects of P-glycoprotein Inhibitors and Inducers in Humans, Using Digoxin, Fexofenadine, and Dabigatran as Probe Drugs.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 6, p. 849, doi. 10.1007/s40262-025-01514-3

By:

Coumau, Claire;
Csajka, Chantal

Publication type:

Article

Selective Inhibition of the ABCG2 Transporter by Primaquine Derivatives Reverses the Multidrug Resistance of Tumor Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5367, doi. 10.3390/ijms26115367

By:

Mioč, Marija;
Beus, Maja;
Carević, Karla;
Rajić, Zrinka;
Sarkadi, Balázs;
Telbisz, Ágnes;
Kralj, Marijeta

Publication type:

Article

Comparative analysis of isoxazoline activity on human and canine GABA receptors expressed in Xenopus oocytes.

Published in:

Parasites & Vectors, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13071-025-06847-3

By:

Sager, Heinz;
Sarr, Anouk;
Kuntz, Emmanuelle;
Rufener, Lucien

Publication type:

Article

外泌体中ISG15在卵巢癌铂类药物耐药中的作用及初步机制探讨.

Published in:

China Oncology, 2025, v. 35, n. 4, p. 346, doi. 10.19401/j.cnki.1007-3639.2025.04.002

By:

田亚楠;
郑慧;
严天晴;
张珩;
卢仁泉;
郭林

Publication type:

Article

Population pharmacokinetics and pharmacogenomics of edoxaban in Japanese adults with atrial fibrillation.

Published in:

Journal of Pharmaceutical Health Care & Sciences, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s40780-025-00453-2

By:

Ueshima, Satoshi;
Hira, Daiki;
Matsuda, Sayana;
Michihata, Rio;
Tabuchi, Yohei;
Ozawa, Tomoya;
Itoh, Hideki;
Iguchi, Moritake;
Akao, Masaharu;
Aizawa, Takanori;
Kashiwa, Asami;
Shizuta, Satoshi;
Makiyama, Takeru;
Nakagawa, Yoshihisa;
Horie, Minoru;
Terada, Tomohiro;
Katsura, Toshiya

Publication type:

Article

ML210 Antagonizes ABCB1- Not ABCG2-Mediated Multidrug Resistance in Colorectal Cancer.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1245, doi. 10.3390/biomedicines13051245

By:

Li, Yan-Chi;
Xiong, Yu-Meng;
Long, Ze-Ping;
Huang, Yi-Ping;
Shu, Yu-Bin;
He, Ke;
Sun, Hong-Yan;
Shi, Zhi

Publication type:

Article

Paliperidone poisoning and measurable plasma concentrations 2.5 years after last administered dose: A case report.

Published in:

British Journal of Clinical Pharmacology, 2025, v. 91, n. 6, p. 1580, doi. 10.1111/bcp.16036

By:

Nersesjan, Mariam;
Wagner, Maria;
Dalhoff, Kim Peder;
Petersen, Tonny Studsgaard;
Bøgevig, Søren;
Horwitz, Henrik

Publication type:

Article

Genotypic Diversity and Molecular Basis of Fluconazole Resistance in Candida parapsilosis Clinical Isolates Collected Over 7 Years in a Tertiary‐Care Hospital in North India.

Published in:

Mycoses, 2025, v. 68, n. 5, p. 1, doi. 10.1111/myc.70062

By:

Sharma, Vrinda;
Das, Sourav;
Spruijtenburg, Bram;
de Groot, Theun;
Meijer, Eelco;
Kaur, Harsimran;
Rudramurthy, Shivaprakash M.;
Ghosh, Anup

Publication type:

Article

Case report: C57BL/6NTac and C57BL/6NCrl mice displaying neurological signs after deworming with ivermectin.

Published in:

Laboratory Animals, 2025, v. 59, n. 3, p. 374, doi. 10.1177/00236772241286214

By:

Eriksson, M.;
Nylén, S.

Publication type:

Article

P-Glycoprotein as a Therapeutic Target in Hematological Malignancies: A Challenge to Overcome.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4701, doi. 10.3390/ijms26104701

By:

Álvarez-Carrasco, Pablo;
Morales-Villamil, Fernanda;
Maldonado-Bernal, Carmen

Publication type:

Article

Insights into Candida auris dispersal cells and their impact on antifungal resistance.

Published in:

BMC Microbiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12866-025-04055-8

By:

Fayed, Bahgat

Publication type:

Article

Mutations in the transcriptional regulator MAB_2885 confer tedizolid and linezolid resistance through the MmpS-MmpL efflux pumps MAB_2302-MAB_2303 in Mycobacterium abscessus.

Published in:

PLoS Pathogens, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.ppat.1013190

By:

Zhang, Huiyun;
Wang, Shiyong;
Zhang, Yu;
Hua, Wenya;
Lin, Siran;
Chen, Xinchang;
Xu, Tao;
Chen, Jiazhen;
Zhang, Wenhong

Publication type:

Article

Erratum to "P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy".

Published in:: 2025
Publication type:: Correction Notice

Paroxysmal atrial fibrillation and depression syndrome: a case report.

Published in:

2013

By:

Eryilmaz, Gul;
Saglam, Esra;
Gul, Isil Gogcegoz

Publication type:

Abstract

Immunohistochemical expression of MDR1-Pgp 170 in canine cutaneous and oral melanomas: pattern of expression and association with tumour location and phenotype.

Published in:

Veterinary & Comparative Oncology, 2017, v. 15, n. 4, p. 1393, doi. 10.1111/vco.12281

By:

Finotello, R.;
Monné Rodriguez, J. M.;
Vilafranca, M.;
Altimira, J.;
Ramirez, G. A.;
Haines, A.;
Ressel, L.

Publication type:

Article

Evaluation of P-glycoprotein expression in feline lymphoma and correlation with clinical outcome.

Published in:

Veterinary & Comparative Oncology, 2008, v. 6, n. 3, p. 201, doi. 10.1111/j.1476-5829.2008.00161.x

By:

Brenn, S. H.;
Couto, S. S.;
Craft, D. M.;
Leung, C.;
Bergman, P. J.

Publication type:

Article

Association ofp53Gene Mutation with the Prognosis of Canine Lymphoid Tumors.

Published in:

Veterinary & Comparative Oncology, 2005, v. 3, n. 1, p. 42, doi. 10.1111/j.1476-5810.2005.0064p.x

By:

Koshino, A.;
Setoguchi, A.;
Ohno, K.;
Tsujimoto, H.

Publication type:

Article

Sequence and structural analysis of the presumed downstream promoter of the canine mdr1 gene.

Published in:

Veterinary & Comparative Oncology, 2003, v. 1, n. 1, p. 30, doi. 10.1046/j.1476-5829.2003.00002.x

By:

Mealey, K. L.;
Bentjen, S. A.

Publication type:

Article

Development of a Library of Thiophene‐Based Drug‐Like Lego Molecules: Evaluation of Their Anion Binding, Transport Properties, and Cytotoxicity.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 4, p. 888, doi. 10.1002/chem.201904255

By:

Vieira, Paulo;
Miranda, Margarida Q.;
Marques, Igor;
Carvalho, Sílvia;
Chen, Li‐Jun;
Howe, Ethan N. W.;
Zhen, Carl;
Leung, Claudia Y.;
Spooner, Michael J.;
Morgado, Bárbara;
Cruz e Silva, Odete A. B.;
Moiteiro, Cristina;
Gale, Philip A.;
Félix, Vítor

Publication type:

Article

Virulence Factors and Azole-Resistant Mechanism of Candida Tropicalis Isolated from Candidemia.

Published in:

Mycopathologia, 2021, v. 186, n. 6, p. 847, doi. 10.1007/s11046-021-00580-y

By:

Sasani, Elahe;
Yadegari, Mohammad Hossein;
Khodavaisy, Sadegh;
Rezaie, Sassan;
Salehi, Mohammadreza;
Getso, Muhammad Ibrahim

Publication type:

Article

The potential therapeutic effect of melatonin in oxaliplatin combination therapy against chemoresistant colorectal cancer cells.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09316-9

By:

Dehghanzad, Masoumeh;
Mohammadi, Mohammad;
Nejati, Mohaddeseh;
Pouremamali, Farhad;
Maroufi, Nazila Fathi;
Akbarzadeh, Maryam;
Samadi, Naser;
Nouri, Mohammad

Publication type:

Article

Cadmium transport by mammalian ATP-binding cassette transporters.

Published in:

BioMetals, 2024, v. 37, n. 3, p. 697, doi. 10.1007/s10534-024-00582-5

By:

Thévenod, Frank;
Lee, Wing-Kee

Publication type:

Article

Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp).

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 1, p. 525, doi. 10.1002/med.21739

By:

Zhang, Hang;
Xu, Haiwei;
Ashby, Charles R.;
Assaraf, Yehuda G.;
Chen, Zhe‐Sheng;
Liu, Hong‐Min

Publication type:

Article

Hybrid molecules with potential in vitro antiplasmodial and in vivo antimalarial activity against drug‐resistant Plasmodium falciparum.

Published in:

Medicinal Research Reviews, 2020, v. 40, n. 3, p. 931, doi. 10.1002/med.21643

By:

Feng, Lian‐Shun;
Xu, Zhi;
Chang, Le;
Li, Chuan;
Yan, Xiao‐Fei;
Gao, Chuan;
Ding, Chao;
Zhao, Feng;
Shi, Feng;
Wu, Xiang

Publication type:

Article

Predicting drug pharmacokinetics and effect in vascularized tumors using computer simulation.

Published in:

Journal of Mathematical Biology, 2009, v. 58, n. 4/5, p. 485, doi. 10.1007/s00285-008-0214-y

By:

Sinek, John;
Sanga, Sandeep;
Zheng, Xiaoming;
Frieboes, Hermann;
Ferrari, Mauro;
Cristini, Vittorio

Publication type:

Article

Brain/blood ratios of methadone and ABCB1 polymorphisms in methadone-related deaths.

Published in:

International Journal of Legal Medicine, 2021, v. 135, n. 2, p. 473, doi. 10.1007/s00414-021-02502-5

By:

Iwersen-Bergmann, S.;
Plattner, S.;
Hischke, S.;
Müller, A.;
Andresen-Streichert, H.;
Jungen, H.;
Erb, R.;
Beer-Sandner, B.

Publication type:

Article

ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram.

Published in:

International Journal of Legal Medicine, 2013, v. 127, n. 3, p. 579, doi. 10.1007/s00414-013-0849-0

By:

Karlsson, L.;
Green, H.;
Zackrisson, A.;
Bengtsson, F.;
Jakobsen Falk, I.;
Carlsson, B.;
Ahlner, J.;
Kugelberg, F.

Publication type:

Article

Post-mortem ABCB1 genotyping reveals an elevated toxicity for female digoxin users.

Published in:

International Journal of Legal Medicine, 2011, v. 125, n. 2, p. 265, doi. 10.1007/s00414-011-0550-0

By:

Neuvonen, Anu M.;
Palo, Jukka U.;
Sajantila, Antti

Publication type:

Article

Rifampicin reduces the plasma concentrations and the renin-inhibiting effect of aliskiren.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 5, p. 497, doi. 10.1007/s00228-010-0796-3

By:

Tapaninen, Tuija;
Neuvonen, Pertti;
Niemi, Mikko

Publication type:

Article

Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: role of P-glycoprotein inhibition by lovastatin.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 285, doi. 10.1007/s00228-009-0757-x

By:

Choi, Dong-Hyun;
Chung, Joong-Hwa;
Choi, Jun-Shik

Publication type:

Article

Is cyclosporine A transport inhibited by pravastatin via multidrug resistant protein 2?

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 2, p. 153, doi. 10.1007/s00228-009-0740-6

By:

Kato, Ryuji;
Nishide, Mami;
Kozu, Chihiro;
Iwamoto, Asuka;
Urashima, Kazuya;
Suzuki, Kaoru;
Ijiri, Yoshio;
Hayashi, Tetsuya;
Tanaka, Kazuhiko

Publication type:

Article

Age dependency of cerebral P-gp function measured with ( R)-[<sup>11</sup>C]verapamil and PET.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 9, p. 941, doi. 10.1007/s00228-009-0709-5

By:

Bauer, Martin;
Karch, Rudolf;
Neumann, Friederike;
Abrahim, Aiman;
Wagner, Claudia C.;
Kletter, Kurt;
Müller, Markus;
Zeitlinger, Markus;
Langer, Oliver

Publication type:

Article

Distribution of fentanyl in the placental intervillous space and in the different maternal and fetal compartments in term pregnant women.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 8, p. 803, doi. 10.1007/s00228-009-0645-4

By:

de Barros Duarte, Luciana;
Moisés, Elaine Cristine Dantas;
Cavalli, Ricardo Carvalho;
Lanchote, Vera Lúcia;
Duarte, Geraldo;
da Cunha, Sérgio Pereira

Publication type:

Article

The impact of everolimus versus mycophenolate on blood and lymphocyte cyclosporine exposure in heart-transplant recipients.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 7, p. 659, doi. 10.1007/s00228-009-0663-2

By:

Gustafsson, Finn;
Barth, David;
Delgado, Diego H.;
Nsouli, Meerna;
Sheedy, Jill;
Ross, Heather J.

Publication type:

Article

Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 6, p. 609, doi. 10.1007/s00228-009-0627-6

By:

Kyoung-Ah Kim;
Pil-Whan Park;
Ji-Young Park

Publication type:

Article

Effect of the novel antipsychotic drug perospirone on P-glycoprotein function and expression in Caco-2 cells.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 7, p. 697, doi. 10.1007/s00228-008-0487-5

By:

Yan-Gang Zhou;
Kun-Yan Li;
Huan-De Li

Publication type:

Article

Drug interaction between oral atorvastatin and verapamil in healthy subjects: effects of atorvastatin on the pharmacokinetics of verapamil and norverapamil.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 5, p. 445, doi. 10.1007/s00228-007-0447-5

By:

Dong-Hyun Choi;
Wan-Gyun Shin;
Jun-Shik Choi

Publication type:

Article

Modelling the influence of MDR1 polymorphism on digoxin pharmacokinetic parameters.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 5, p. 437, doi. 10.1007/s00228-007-0269-5

By:

Comets, Emmanuelle;
Verstuyft, Céline;
Lavielle, Marc;
Jaillon, Patrice;
Becquemont, Laurent;
Mentré, France

Publication type:

Article

The effect of 3435C>T MDR1 gene polymorphism on rheumatoid arthritis treatment with disease-modifying antirheumatic drugs.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 11, p. 933, doi. 10.1007/s00228-006-0192-1

By:

Drozdzik, Marek;
Rudas, Tomasz;
Pawlik, Andrzej;
Kurzawski, Mateusz;
Czerny, Bogusław;
Gornik, Wanda;
Herczynska, Magdalena

Publication type:

Article

Transport studies with 5-aminosalicylate.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 10, p. 871, doi. 10.1007/s00228-006-0182-3

By:

Xin, Hua-Wen;
Schwab, Matthias;
Klotz, Ulrich

Publication type:

Article

Influence of carvedilol on serum digoxin levels in heart failure: is there any gender difference?

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 7, p. 535, doi. 10.1007/s00228-006-0138-7

By:

Baris, Nezihi;
Kalkan, Sule;
Güneri, Sema;
Bozdemir, Volkan;
Guven, Hulya

Publication type:

Article

Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 6, p. 463, doi. 10.1007/s00228-006-0133-z

By:

Niemi, Mikko;
Tornio, Aleksi;
Pasanen, Marja K.;
Fredrikson, Hanna;
Neuvonen, Pertti J.;
Backman, Janne T.

Publication type:

Article

Effect of CYP2C19 and MDR1 polymorphisms on cure rate in patients with acid-related disorders with Helicobacter pylori infection.

Published in:

European Journal of Clinical Pharmacology, 2005, v. 61, n. 5/6, p. 375, doi. 10.1007/s00228-005-0901-1

By:

Gawrońska-Szklarz, Barbara;
Wrześniewska, Joanna;
Starzyńska, Teresa;
Pawlik, Andrzej;
Safranow, Krzysztof;
Ferenc, Katarzyna;
Droździk, Marek

Publication type:

Article

Polymorphism in the P-glycoprotein drug transporter MDR1 gene in colon cancer patients.

Published in:

European Journal of Clinical Pharmacology, 2005, v. 61, n. 5/6, p. 389, doi. 10.1007/s00228-005-0926-5

By:

Kurzawski, Mateusz;
Droździk, Marek;
Suchy, Janina;
Kurzawski, Grzegorz;
Białecka, Monika;
Górnik, Wanda;
Lubiński, Jan

Publication type:

Article

P-glycoprotein function in the elderly.

Published in:

European Journal of Clinical Pharmacology, 2004, v. 60, n. 2, p. 97, doi. 10.1007/s00228-004-0733-4

By:

Brenner, Stefanie S.;
Klotz, Ulrich

Publication type:

Article

Rifampicin reduces plasma concentrations of celiprolol.

Published in:

European Journal of Clinical Pharmacology, 2004, v. 59, n. 11, p. 819, doi. 10.1007/s00228-003-0694-z

By:

Lilja, J. J.;
Niemi, M.;
Neuvonen, P. J.

Publication type:

Article

Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 4, p. 303, doi. 10.1007/s00228-003-0606-2

By:

Gaikovitch, Elena A.;
Cascorbi, Ingolf;
Mrozikiewicz, Przemyslaw M.;
Brockmöller, Jürgen;
Frötschl, Roland;
Köpke, Karla;
Gerloff, Thomas;
Chernov, Jury N.;
Roots, Ivar

Publication type:

Article

Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 92, n. 2, p. 337, doi. 10.1007/s00253-011-3439-4

By:

Qiu, Jingfan;
Zhuo, Ying;
Zhu, Dongqing;
Zhou, Xiufen;
Zhang, Lixin;
Bai, Linquan;
Deng, Zixin

Publication type:

Article

Vectorial transport of the arginine derivatives asymmetric dimethylarginine (ADMA) and l-homoarginine by OATP4C1 and P-glycoprotein studied in double-transfected MDCK cells.

Published in:

Amino Acids, 2020, v. 52, n. 6/7, p. 975, doi. 10.1007/s00726-020-02867-8

By:

Taghikhani, Emir;
Maas, Renke;
Taudte, R. Verena;
Gessner, Arne;
Fromm, Martin F.;
König, Jörg

Publication type:

Article