Works matching DE "MITOGEN-activated protein kinases"

Results: 5000

Unveiling the role of tyrosine kinases in doxorubicin-induced cardiotoxicity and beyond Free.

Published in:

Cardiovascular Research, 2025, v. 121, n. 4, p. 530, doi. 10.1093/cvr/cvaf035

By:

Lazzarini, Edoardo;
Altomare, Claudia;
Barile, Lucio

Publication type:

Article

Thousand and one amino acid protein kinase 1 suppression improves doxorubicin-induced cardiomyopathy by preventing cardiomyocyte death and dysfunction.

Published in:

Cardiovascular Research, 2025, v. 121, n. 4, p. 601, doi. 10.1093/cvr/cvaf022

By:

Suga, Takaomi;
Kitani, Tomoya;
Kogure, Masaya;
Oishi, Masatsugu;
Ito, Fumiaki;
Hoshino, Atsushi;
Ogata, Takehiro;
Ikeda, Koji;
Matoba, Satoaki

Publication type:

Article

低强度脉冲超声促进牙种植体骨结合的研究进展.

Published in:

Journal of Prevention & Treatment For Stomatological Diseases, 2025, v. 33, n. 5, p. 417, doi. 10.12016/j.issn.2096-1456.202440418

By:

张昕宇;
瞿方;
胥春

Publication type:

Article

Polystyrene nanoplastics exposure induces cognitive impairment in mice via induction of oxidative stress and ERK/MAPK-mediated neuronal cuproptosis.

Published in:

Particle & Fibre Toxicology, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12989-025-00633-w

By:

Chen, Yinuo;
Nan, Yiyang;
Xu, Lang;
Dai, Anqi;
Orteg, Rosa Maria Martinez;
Ma, Mantong;
Zeng, Yan;
Li, Jinquan

Publication type:

Article

Contribution of p38 MAPK to Endoplasmic Reticulum Stress-Mediated Apoptosis in Cardiomyocytes.

Published in:

Biology Bulletin, 2025, v. 52, n. 2, p. 1, doi. 10.1134/S1062359024600399

By:

Hongyun Jin;
Guo, Zhihua;
Huang, Qianlan;
Cai, Bin;
Chen, Xing

Publication type:

Article

Korean red ginseng extracts alleviate skin damage in heat-stimulated skin cells by suppressing NF-κB activation.

Published in:

Archives of Biological Sciences, 2025, v. 77, n. 1, p. 83, doi. 10.2298/ABS250214008K

By:

Jeeyoung Kim;
Weon Jeong Bang;
Yung Hyup Joo;
Sung Hyeon Lee;
Chang-Seok Lee

Publication type:

Article

Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1554850

By:

Ren, Guilin;
Lin, Yiyou;
Qiu, Jiannan;
Zhang, Congcong;
Chen, Lin;
Zhu, Linwensi;
Fan, Xiaohui;
Dou, Xiaobing;
Liu, Qingsheng

Publication type:

Article

The Activation of the CCND1 Promoter by AP-1 and SOX Transcription Factors in PC3 Prostate Cancer Cells Can Be Prevented by Anacardic Acid Analogs.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2349, doi. 10.1007/s12013-024-01646-6

By:

Brunie, Manon;
Robichaud, Mika A.;
Touaibia, Mohamed;
Martin, Luc J.

Publication type:

Article

Caffeic Acid Phenethyl Ester Enhances Bone Repair-related Factors in MC3T3-E1 Cells.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2323, doi. 10.1007/s12013-024-01644-8

By:

Kuramoto, Hitomi;
Nakanishi, Tadashi;
Yumoto, Hiromichi;
Takegawa, Daisuke;
Mieda, Katsuhiro;
Hosaka, Keiichi

Publication type:

Article

Bioinformatics and Gene Expression Omnibus Analysis of Key Candidate Genes and Pathways Associated with Femoral Head Necrosis.

Published in:

IJ Pharmaceutical Research (IJPR), 2024, v. 23, n. 1, p. 1, doi. 10.5812/ijpr-145223

By:

Ding, Yuanjing;
Ma, Yuxia;
Yan, Heng;
Zhang, Enshui

Publication type:

Article

Natural traditional Chinese medicine products: emerging therapeutic targets for the treatment of osteoporosis.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05879-w

By:

Liu, Bo;
Mao, Xue;
Gao, Zhe-Jian-Yi;
Wang, Huan

Publication type:

Article

Nebulized inhalation of extracellular vesicles containing SPOCK2 suppresses lung adenocarcinoma progression via MAPK inhibition.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02626-9

By:

Wang, Ying;
Liu, Ningning;
Xu, Chuanqin;
Wang, Jing;
Dong, Liyang;
Yang, Shuang;
Jiang, Junhong

Publication type:

Article

Phytochemical analysis and biological effects of Zingiber cassumunar extract and three phenylbutenoids: targeting NF-κB, Akt/MAPK, and caspase-3 pathways.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04907-w

By:

Gundom, Thidaporn;
Sukketsiri, Wanida;
Panichayupakaranant, Pharkphoom

Publication type:

Article

Genome-wide identification and molecular characterization of the MAPK family members in sand pear (Pyrus pyrifolia).

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11672-0

By:

Xu, Yue;
Wang, Huiying;
Shi, Haiyan

Publication type:

Article

MEK1/2 inhibitors suppress pathological α-synuclein and neurotoxicity in cell models and a humanized mouse model of Parkinson's disease.

Published in:

Science Translational Medicine, 2025, v. 17, n. 798, p. 1, doi. 10.1126/scitranslmed.adp4625

By:

Wang, Huilan;
Wang, Qing;
Xu, Haoxiang;
Wu, Yuanzheng;
Cheung, Siulam;
Xu, Qianhui;
Pan, Chengfang;
Cao, Jingyu;
Cao, Zhiyuan;
Yang, Ruonan;
Ding, Yu;
Fei, Yiyan;
Chen, Yongfeng;
Wang, Jian;
Liu, Cong;
Lu, Boxun

Publication type:

Article

مالتیپل اسکلروزیس و مسیر سیگنال دهی MAPK یک مطالعه مبتنی بر ریز آرایه.

Published in:

Pars Journal of Medical Sciences, 2025, v. 22, n. 4, p. 72

By:

میرزا علی مفضل جه
امیررضا دهقان;
اباذر روستازاده

Publication type:

Article

Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103615

By:

Qian Wang;
Hongge Li;
Yingyu Mao;
Garg, Ankur;
Eun Sil Park;
Yihua Wu;
Chow, Alyssa;
Peregrin, John;
Xin Zhang

Publication type:

Article

斑皮柠檬桉新芽枯萎病病变过程的转录组动态分析.

Published in:

Southwest China Journal of Agricultural Sciences, 2025, v. 38, n. 2, p. 315, doi. 10.16213/j.cnki.scjas.2025.2.011

By:

甘春雁;
唐庆兰;
朱慧;
邓紫宇;
李昌荣;
陈升侃

Publication type:

Article

Current Treatment of Uveal Melanoma.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1403, doi. 10.3390/cancers17091403

By:

Hanratty, Katie;
Finegan, Gráinne;
Rochfort, Keith D.;
Kennedy, Susan

Publication type:

Article

Molecular Regulation of Carotenoid Accumulation Enhanced by Oxidative Stress in the Food Industrial Strain Blakeslea trispora.

Published in:

Foods, 2025, v. 14, n. 9, p. 1452, doi. 10.3390/foods14091452

By:

Deng, Jiawei;
Chen, Yuyang;
Lin, Siting;
Shao, Yilu;
Zou, Yuan;
Zheng, Qianwang;
Guo, Liqiong;
Lin, Junfang;
Chen, Moutong;
Ye, Zhiwei

Publication type:

Article

Formononetin: a review of its anti-inflammatory properties and mechanisms.

Published in:

Quality Assurance & Safety of Crops & Foods, 2025, v. 17, n. 2, p. 1, doi. 10.15586/qas.v17i2.1543

By:

Dou, Jiawen;
Pryvalau, Fiodar;
Goncharova, Liudmila;
Li, Yongping;
He, Min;
Sun, Mengmeng

Publication type:

Article

Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.

Published in:

Journal of Cancer, 2025, v. 16, n. 7, p. 2339, doi. 10.7150/jca.92956

By:

Xiaonan Yang;
Zhimin Ding;
Hongting Hua;
Ruijia Gan;
Dongdong Meng;
Yan Zang;
Han Xiao;
Dong Wang;
Wanjin Jiang;
Dongyu Si;
Xiang Wei;
Mei Zhang;
Huabing Zhang;
Chaobing Gao

Publication type:

Article

Resveratrol and N-acetylcystein reduce hepatic steatosis but enhance initiation and progression of hepatocellular carcinoma by inhibiting GST-pi-MAPK axis in mice.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1574039

By:

Zhang, Mi;
Yuan, Weigang;
Li, Chun;
Chen, Chanyuan;
Liu, Xiang;
Ma, Zhilu;
Xiang, Yifei;
Chen, Guisha;
Wang, Chunxu;
Li, Lei;
Wang, Lingli;
Xu, Zhong;
Xu, Chuanrui

Publication type:

Article

ANO1: central role and clinical significance in non-neoplastic and neoplastic diseases.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1570333

By:

Hu, Yanghao;
Zhang, Yifei;
He, Jiali;
Rao, Huihuang;
Zhang, Duomi;
Shen, Zhisen;
Zhou, Chongchang

Publication type:

Article

Epidermal growth factor receptors unveiled: a comprehensive survey on mutations, clinical insights of global inhibitors, and emergence of heterocyclic derivatives as EGFR inhibitors.

Published in:

Journal of Drug Targeting, 2025, v. 33, n. 6, p. 933, doi. 10.1080/1061186X.2024.2449495

By:

C, Manojmouli;
Pasha, T. Y.;
Rahamathulla, Mohamed;
H P, Gagana;
B L, Kavya;
K M, Gagana;
K N, Purushotham;
Hussain, Shalam M.;
Ahmed, Mohammed Muqtader;
Shivanandappa, Thippeswamy Boreddy;
Pasha, Ismail

Publication type:

Article

Genome-wide identification, phylogenetic investigation and abiotic stress responses analysis of the PP2C gene family in litchi (Litchi chinensis Sonn.).

Published in:

Frontiers in Plant Science, 2025, p. 1, doi. 10.3389/fpls.2025.1547526

By:

Yang, Jie;
Chen, Rong;
Liu, Wei;
Fan, Chao

Publication type:

Article

The roles, signalling pathways and therapeutic implications of Apoc1 in cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02313-9

By:

Guo, Hao-Han;
Guo, Qiang;
Zhang, Qun-Xian;
Li, Dan;
Lv, Yan

Publication type:

Article

Mechanisms of the JNK/p38 MAPK signaling pathway in drug resistance in ovarian cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1533352

By:

Ma, Yu-Ting;
Li, Chan;
Shen, Ying;
You, Wan-Hui;
Han, Ming-Xuan;
Mu, Yi-Fan;
Han, Feng-Juan

Publication type:

Article

Parthenolide ameliorates glucocorticoid-induced inhibition of osteogenic differentiation and osteoporosis by activating ERK signaling pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05722-2

By:

Feng, Yanling;
Li, Zhaoyang

Publication type:

Article

Rice grain size: current regulatory mechanisms and future perspectives.

Published in:

Journal of Plant Research, 2025, v. 138, n. 3, p. 403, doi. 10.1007/s10265-025-01626-8

By:

Yaseen, Muhammad;
Tariq, Naveed;
Kanwal, Rida;
Farooq, Akasha;
Wang, Hao;
Yuan, Hua

Publication type:

Article

Immature Citrus unshiu fruit extracts inhibit adipogenesis in 3T3-L1 adipocytes via AMPK and MAPK signaling pathways.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322619

By:

Kim, Min Gun;
Boo, Kyung-Hwan;
Kim, Jae-Hoon;
Kim, Chang Sook

Publication type:

Article

Toll‐Like Receptors in Pentachlorophenol‐ and Dibutyltin‐Induced Production of Pro‐Inflammatory Cytokines, Interleukin (IL)‐1β, and IL‐6, by Human Immune Cells.

Published in:

Journal of Applied Toxicology, 2025, v. 45, n. 6, p. 976, doi. 10.1002/jat.4762

By:

Seaton‐Terry, Aleshia;
Hunter, Zinia;
Lewis, Meaghan;
Fisher, Sophia;
Bray, Ellie;
Townsend, Brian;
Gabure, Saleban;
Daniel, Latoya;
Whalen, Margaret

Publication type:

Article

草苁蓉多糖对 THP-1 巨噬细胞炎症反应的抑制作用及其机制.

Published in:

Journal of Jilin University (Medicine Edition), 2024, v. 50, n. 6, p. 1499, doi. 10.13481/j.1671⁃587X.20240603

By:

马新月;
徐慧;
刁佳雯;
金爱花;
全吉淑

Publication type:

Article

Effect of silencing Ras homolog family member C on proliferation, invasion, and migration of salivary adenoid cystic carcinoma.

Published in:

West China Journal of Stomatology, 2024, v. 42, n. 6, p. 723, doi. 10.7518/hxkq.2024.2024092

By:

Yu Wenyuan;
Zhao Peng;
Shao Yu;
Xu Yong;
Xu Jin;
Xie Lei;
Yu Chenghao;
He Qiuping;
Chen Zhenggang

Publication type:

Article

基于网络药理学的益母草防控母畜产后炎症性疾病的分子机制研究.

Published in:

Feed Research, 2025, v. 48, n. 5, p. 78, doi. 10.13557/j.cnki.issn1002-2813.2025.05.014

By:

廖玲玲;
宣泽义;
陈少梅;
曹艳红;
奚玉莲;
谢恒生;
黄焕昌;
胡湘云

Publication type:

Article

MicroRNA‐371–373 cluster and methylome analysis suggests that a subset of 'somatic‐type' malignancies arising in germ cell tumors may originate in yolk sac tumor components.

Published in:

Journal of Pathology, 2025, v. 266, n. 2, p. 160, doi. 10.1002/path.6412

By:

Lobo, João;
Tavares, Nuno Tiago;
Fonseca, Diana;
Jerónimo, Carmen;
Henrique, Rui;
Wyvekens, Nicolas;
Yang, Yiying;
Snuderl, Matija;
Maclean, Fiona;
Gordetsky, Jennifer;
Fletcher, Christopher DM;
Hirsch, Michelle S;
Hornick, Jason L;
Idrees, Muhammad T;
Collins, Katrina;
Warmke, Laura;
Ulbright, Thomas M;
Acosta, Andres M

Publication type:

Article

Shear Wave Elastography: A Non-Invasive Approach for Assessing TGF-β1/MAPK Signaling Molecules and EMT in Breast Cancer.

Published in:

Breast Cancer: Targets & Therapy, 2025, v. 17, p. 275, doi. 10.2147/BCTT.S498497

By:

Huang, Sisi;
Wang, Bo;
Jiang, Ying;
Li, Shiyu;
Li, Junkang;
Wang, Zhili

Publication type:

Article

MiR-340-5p alleviates AECOPD by targeting MAP3K2 via Qingjin Huatan decoction therapy.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 4, p. 1, doi. 10.1093/jleuko/qiaf021

By:

Zhao, Mei;
Huang, Zhijian;
Zheng, Jinghui;
Li, Wanying;
Zhong, Yunqing;
Ouyang, Tun

Publication type:

Article

In Vitro Study of Cancer Stem Cells and Reprogrammed CD3+CD8+ T Cells: the Search for Personalized Diagnostics and Targeted Treatment of Small Cell Lung Cancer (Experience of a Pilot Study).

Published in:

Bulletin of Experimental Biology & Medicine, 2025, v. 178, n. 5, p. 631, doi. 10.1007/s10517-025-06388-w

By:

Skurikhin, E. G.;
Ermakova, N. N.;
Zhukova, M. A.;
Pan, E. S.;
Kubatiev, A. A.;
Morozov, S. G.;
Dygai, A. M.

Publication type:

Article

RETRACTION NOTE: EFFECT OF PROPOFOL ON MYOCARDIAL ISCHEMIA-REPERFUSION INJURY THROUGH MAPK/ERK PATHWAY.

Published in:: European Review for Medical & Pharmacological Sciences, 2025, v. 29, n. 4, p. 149
Publication type:: Article

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1511627

By:

Muslim, Wisam Taher;
Mohammad, Layth Jasim;
Naji, Munaf M.;
Karimi, Isaac;
Al-Sabti, Matheel D.;
Jabir, Majid;
Najm, Mazin A. A.;
Schiöth, Helgi B.

Publication type:

Article

Andrographolide Reduces Cytokine Release and Cyclooxygenase-2 Expression by Inhibiting the JNK and NF-κB Pathways in Glioblastoma Cells Exposed to Cadmium.

Published in:

Journal of Experimental Pharmacology, 2025, v. 17, p. 169, doi. 10.2147/JEP.S506062

By:

Kasemsuk, Thitima;
Vivithanaporn, Pornpun;
Woonfak, Pichsinee;
Khemawoot, Phisit

Publication type:

Article

Genome-wide identification of the regulatory network of mitogen-activated protein kinase signaling cascades gene families in Hevea Brasiliensis.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06615-6

By:

Huang, Xiaojuan;
Sun, Manman;
Du, Xiaoyu;
Quan, Lin;
Chao, Jinquan;
Deng, Xiaomin;
Liao, Hongze

Publication type:

Article

Evaluating Oncogenic Drivers and Therapeutic Potential of the PI3K/AKT/mTOR Pathway in Hepatocellular Carcinoma: An Overview of Clinical Trials.

Published in:

Biocell, 2025, v. 49, n. 4, p. 539, doi. 10.32604/biocell.2025.059970

By:

Khorasani, Ayda Baghery Saghchy;
Delshad, Mahda;
Sanaei, Mohammad-Javad;
Pourbagheri-Sigaroodi, Atieh;
Pirsalehi, Ali;
Bashash, Davood

Publication type:

Article

Obacunone acts as a histone deacetylase 1 inhibitor to limit p38MAPK signaling and alleviate osteoarthritis progression.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05804-1

By:

Gao, Yong;
Wang, Ke;
Shi, Chao;
Gao, Yang;
Kong, De-Qian

Publication type:

Article

Exploring the mechanism of sunflower seed oil against Alzheimer's disease through experimental and network pharmacology studies.

Published in:

Indian Journal of Pharmacology, 2024, v. 56, n. 6, p. 396, doi. 10.4103/ijp.ijp_761_23

By:

Desai, Yashodhan;
Karunakaran, Deepak;
Singh, Juhi;
Noronha, Alric Raul;
Poojary, Gagan;
Chettri, Bijaya;
Shenoy, Rekha;
Nampoothiri, Madhavan;
Bojja, Sree Lalitha

Publication type:

Article

Off-target effect of high-dose sildenafil on adenosine 5'-diphosphate and collagen-induced platelet activation through mitogen-activated protein kinase pathway in treated BALB/C mice and in vitro experiments: A preliminary study.

Published in:

Indian Journal of Pharmacology, 2024, v. 56, n. 2, p. 136, doi. 10.4103/ijp.ijp_312_23

By:

Balaji, Sudharshanan;
Patnaik, Yash Raj;
Surin, William Rasican

Publication type:

Article

Characterization of Greenbeard Genes Involved in Long-Distance Kind Discrimination in a Microbial Eukaryote.

Published in:

PLoS Biology, 2016, v. 14, n. 4, p. 1, doi. 10.1371/journal.pbio.1002431

By:

Heller, Jens;
Zhao, Jiuhai;
Rosenfield, Gabriel;
Kowbel, David J.;
Gladieux, Pierre;
Glass, N. Louise

Publication type:

Article

The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System.

Published in:

PLoS Biology, 2015, v. 13, n. 3, p. 1, doi. 10.1371/journal.pbio.1002107

By:

Jarjour, Andrew A.;
Boyd, Amanda;
Dow, Lukas E.;
Holloway, Rebecca K.;
Goebbels, Sandra;
Humbert, Patrick O.;
Williams, Anna;
ffrench-Constant, Charles

Publication type:

Article

Growth Cone MKK7 mRNA Targeting Regulates MAP1b-Dependent Microtubule Bundling to Control Neurite Elongation

Published in:

PLoS Biology, 2012, v. 10, n. 12, p. 1, doi. 10.1371/journal.pbio.1001439

By:

Feltrin, Daniel;
Fusco, Ludovico;
Witte, Harald;
Moretti, Francesca;
Martin, Katrin;
Letzelter, Michel;
Fluri, Erika;
Scheiffele, Peter;
Pertz, Olivier

Publication type:

Article