Works matching DE "TRANSGENIC mice"

Results: 5000

Immunological and Toxicological Assessment of Triterpenoid Saponins Bearing Lewis‐X‐ and QS‐21‐Based Trisaccharides.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 28, p. 1, doi. 10.1002/chem.202500994

By:

Gamboa Marin, Oscar Javier;
Adda‐Bouchard, Yasmine;
Sylla, Balla;
Verma, Nitish;
Charpentier, Tania;
Huber, Maya;
Lopez, Guillaume;
Pichette, André;
Lamarre, Alain;
Gauthier, Charles

Publication type:

Article

PINK1-mediated mitophagy attenuates pathological cardiac hypertrophy by suppressing the mtDNA release-activated cGAS-STING pathway.

Published in:

Cardiovascular Research, 2025, v. 121, n. 1, p. 128, doi. 10.1093/cvr/cvae238

By:

Zhou, Haobin;
Wang, Xiao;
Xu, Tianyu;
Gan, Daojing;
Ma, Zhuang;
Zhang, Hao;
Zhang, Jian;
Zeng, Qingchun;
Xu, Dingli

Publication type:

Article

TREM2 deficiency exacerbates cognitive impairment by aggravating α-Synuclein-induced lysosomal dysfunction in Parkinson's disease.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02538-1

By:

Zhu, Baoyu;
Feng, Jiezhu;
Liang, Xiaomei;
Fu, Zhongling;
Liao, Mengshi;
Deng, Tongtong;
Wang, Kaicheng;
Xie, Jianwei;
Chi, Jieshan;
Yang, Lu;
Gao, Yuyuan;
Nie, Kun;
Wang, Lijuan;
Zhang, Piao;
Zhang, Yuhu

Publication type:

Article

Atorvastatin Protects Against the Macrophage/Microglia-Related Neuroinflammation via Inhibiting Lipocalin-2 in Mouse Experimental Intracerebral Hemorrhage Model.

Published in:

Cellular & Molecular Neurobiology, 2025, v. 45, n. 1, p. 1, doi. 10.1007/s10571-025-01566-w

By:

Wang, Guangming;
Hu, Hongkang;
Liu, Junbin;
Fei, Xiaowei;
Dou, Yanan;
Wang, Li;
Ying, Lin;
Hu, Guohan;
Zhang, Danfeng;
Jiang, Lei;
Wei, Jialiang

Publication type:

Article

Benchmark Response (BMR) Values for In Vivo Mutagenicity Endpoints.

Published in:

Environmental & Molecular Mutagenesis, 2025, v. 66, n. 4, p. 172, doi. 10.1002/em.70006

By:

White, Paul A.;
Chen, Guangchao;
Chepelev, Nikolai;
Bell, Madison A.;
Gallant, Lauren R.;
Johnson, George E.;
Zeller, Andreas;
Beal, Marc A.;
Long, Alexandra S.

Publication type:

Article

甲基转移酶 METTL3 在卵巢早衰中的作用机制.

Published in:

Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2025, v. 46, n. 3, p. 11, doi. 10.12259/j.issn.2095-610X.S20250303

By:

潘正美;
吴妍芝;
孙春意;
耿肖玉捷;
刘洋

Publication type:

Article

Pup numbers weaned are higher in backcrossed colonies of genetically altered mice than non-backcrossed colonies.

Published in:

Animal Technology & Welfare, 2025, v. 24, n. 1, p. 77

By:

COLQUHOUN, ROSS;
TRAILL, SAMANTHA;
GILLAN, CATHERINE;
BOOTH, KALLY;
DENNISON, NGAIRE;
GILMOUR, GAIL

Publication type:

Article

Direct Stimulation of Gastric Smooth Muscle Cells via G<sub>q</sub> Proteins With Light.

Published in:

Neurogastroenterology & Motility, 2025, v. 37, n. 6, p. 1, doi. 10.1111/nmo.70028

By:

Zipf, David;
Vogt, Markus;
Sathyanarayanan, Udhayabhaskar;
Wagdi, Ahmed;
Riebeling, Johannes;
Patejdl, Robert;
Bruegmann, Tobias

Publication type:

Article

Resveratrol attenuates the priapism phenotype in sickle cell mice by restoring NO-cGMP-PDE5 signaling and reducing NADPH oxidase 2 expression.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1551533

By:

Splendore, Carolina Oliveira;
Silveira, Tammyris Helena Rebecchi;
Pereira, Dalila Andrade;
Bossarino, Beatriz Pereira;
de Oliveira, Mariana Gonçalves;
Calmasini, Fabiano Beraldi;
Burnett, Arthur L.;
Costa, Fernando Ferreira;
Silva, Fábio Henrique

Publication type:

Article

Structure-guided design of endosomolytic chloroquine-like lipid nanoparticles for mRNA delivery and genome editing.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59501-y

By:

Liu, Zhen;
Wu, Jiacai;
Wang, Ning;
Lin, Yongqi;
Song, Ruiteng;
Zhang, Min;
Li, Bin

Publication type:

Article

Chronic silencing of Drd1a-Cre+ neurons impairs dopaminergic-driven cortical activation.

Published in:

Frontiers in Neuroanatomy, 2025, p. 1, doi. 10.3389/fnana.2025.1548545

By:

Messore, Luis Fernando;
Vadisiute, Auguste;
Edmead, Hayley;
Durmaz, Aleisha;
Abuelem, Mohammed;
Chedotal, Flore;
Hoerder-Suabedissen, Anna;
Mann, Edward Oliver;
Molnár, Zoltán

Publication type:

Article

Role of intraflagellar transport protein IFT140 in the formation and function of motile cilia in mammals.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05710-z

By:

Yap, Yi Tian;
Pan, Jiehong;
Xu, Jian;
Yuan, Shuo;
Niu, Changmin;
Zheng, Cheng;
Li, Wei;
Zhou, Ting;
Li, Tao;
Zhang, Yong;
Holtzman, Michael J.;
Pazour, Gregory J.;
Hess, Rex A.;
Kelly, Christopher V.;
Touré, Aminata;
Brody, Steven L.;
Zhang, Zhibing

Publication type:

Article

Exploring the Chemopreventive and Antioxidant Effects of Spearmint Leaf Hydroethanolic Extract in HPV16-transgenic Mice.

Published in:

In Vivo, 2025, v. 39, n. 3, p. 1303, doi. 10.21873/invivo.13934

By:

JESUS, TIAGO M.;
AZEVEDO, TIAGO;
SILVA‐REIS, RITA;
FERREIRA, TIAGO;
NASCIMENTO‐GONÇALVES, ELISABETE;
MEDEIROS, CATARINA;
FERREIRA, JOÃO;
GAMA, ADELINA;
GAIVÃO, ISABEL;
PIRES, MARIA JOÃO;
LANZARIN, GERMANO;
FÉLIX, LUÍS;
VENÂNCIO, CARLOS;
MEDEIROS, RUI;
BASTOS, MARGARIDA M. S. M.;
FINIMUNDY, TIANE C.;
BARROS, LILLIAN;
GIL DA COSTA, RUI M.;
OLIVEIRA, PAULA A.

Publication type:

Article

Oligodendrocyte-specific overexpression of human alpha-synuclein results in elevated MBP levels and inflammatory responses in TgM83 mice, mimicking the pathological features of multiple system atrophy.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-02014-y

By:

Liu, Sam Chi-Hao;
Chang, Koping;
Chen, Meng-Ling;
Kuo, Ming-Che;
Wang, Teh-Cheng;
Wu, Ruey-Meei

Publication type:

Article

Selective Deletion of HLA-B, and -C Class I Genes Promotes Immunocompatibility of Humanized Skin Graft Model.

Published in:

ImmunoTargets & Therapy, 2025, v. 14, p. 451, doi. 10.2147/ITT.S506352

By:

Cobos-Figueroa, Laura;
Notario, Laura;
Mir, Carmen;
Molpeceres, Carlos;
Lauzurica, Sara;
López, Daniel;
Lorente, Elena;
Lauzurica, Pilar

Publication type:

Article

Human cytomegalovirus-IE2 suppresses antigen presentation of macrophage through the IL10/STAT3 signalling pathway in transgenic mouse.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322334

By:

Zhang, Xianjuan;
Wang, Qing;
Han, Shuo;
Song, Guanghui;
Wang, Bin;
Wang, Yunyang

Publication type:

Article

Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322732

By:

Santos, Leonardo;
Fort, Rafael Sebastián;
Schlapp, Geraldine;
Cal, Karina;
Perez-Torrado, Valentina;
Meikle, Maria Noel;
Mulet, Ana Paula;
Espasandín, Camila;
Chiesa, Camila;
Sotelo-Silveira, José R.;
Verdes, Jose M.;
Contreras, Paola;
Calliari, Aldo J.;
Crispo, Martina;
Badano, Jose L.;
Escande, Carlos

Publication type:

Article

A Conserved CXXC Motif in CD3ε Is Critical for T Cell Development and TCR Signaling.

Published in:

PLoS Biology, 2009, v. 7, n. 12, p. 1, doi. 10.1371/journal.pbio.1000253

By:

Yibing Wang;
Becker, Dean;
Vass, Tibor;
White, Janice;
Marrack, Philippa;
Kappler, John W.

Publication type:

Article

Critical Role of Gap Junction Coupled KATP Channel Activity for Regulated Insulin Secretion.

Published in:

PLoS Biology, 2006, v. 4, n. 2, p. e26, doi. 10.1371/journal.pbio.0040026

By:

Rocheleau, Jonathan V.;
Remedi, Maria S.;
Granada, Butch;
Head, W. Steven;
Koster, Joseph C.;
Nichols, Colin G.;
Piston, David W.

Publication type:

Article

β-Galactosidase detection as an indicator of endogenous PTHrP in cartilage.

Published in:

Biotechnic & Histochemistry, 2008, v. 83, n. 2, p. 89, doi. 10.1080/10520290802127834

By:

Chen, X-S;
Troiano, Nw;
Kacena, Ma

Publication type:

Article

Neuronal expression of enhanced green fluorescent protein directed by 5' flanking sequences of the rat aldolase C gene in transgenic mice.

Published in:

Biotechnic & Histochemistry, 2003, v. 78, n. 3/4, p. 179, doi. 10.1080/10570290310001594035

By:

Phan-Dinh-Tuy, F.;
Souil, E.;
Kahn, A.;
Skala-Rubinson, H.

Publication type:

Article

Identification and culture of olfactory neural progenitors from GFP mice.

Published in:

Biotechnic & Histochemistry, 2003, v. 78, n. 2, p. 57, doi. 10.1080/10520290310001593801

By:

Othman, M. M.;
Klueber, K. M.;
Roisen, F. J.

Publication type:

Article

Unique food-entrained circadian rhythm in cysteine414-alanine mutant mCRY1 transgenic mice.

Published in:

Sleep & Biological Rhythms, 2016, v. 14, n. 3, p. 261, doi. 10.1007/s41105-016-0050-1

By:

Okano, Satoshi;
Yasui, Akira;
Hayasaka, Kiyoshi;
Nakajima, Osamu

Publication type:

Article

Interaction between sleep mechanisms and orexin neurons.

Published in:

Sleep & Biological Rhythms, 2011, v. 9, p. 38, doi. 10.1111/j.1479-8425.2010.00466.x

By:

Hara, Junko;
Sakurai, Takeshi

Publication type:

Article

Role of PPARα in control of torpor through FGF21–NPY pathway: From circadian clock genes to seasonal change and cardiovascular disease.

Published in:

Sleep & Biological Rhythms, 2010, v. 8, n. 1, p. 2, doi. 10.1111/j.1479-8425.2009.00413.x

By:

ISHIDA, Norio K.;
UCHIDA, Daisuke;
DOI, Ryosuke;
OISHI, Katsutaka;
CHIKAHISA, Sachiko;
SEI, Hiroyoshi;
HAMASAKA, Yasutaka;
SUZUKI, Takahiro;
HANAI, Shuji

Publication type:

Article

ORAL PRESENTATION Effect of PLCβ4 in the thalamus on the EEG in REM sleep.

Published in:

Sleep & Biological Rhythms, 2004, v. 2, p. S42, doi. 10.1111/j.1479-8425.2004.00104.x

By:

Yoshioka, Tohru

Publication type:

Article

POSTER PRESENTATION Prostaglandin D synthase: From X-ray crystallography to gene manipulation.

Published in:

Sleep & Biological Rhythms, 2004, v. 2, p. S59, doi. 10.1111/j.1479-8425.2004.00118.x

By:

Urade, Yoshihiro;
Eguchi, Naomi;
Hayishi, Osamu

Publication type:

Article

POSTER PRESENTATION Regulation of orexin neurons by the monoaminergic and cholinergic systems.

Published in:

Sleep & Biological Rhythms, 2004, v. 2, p. S60, doi. 10.1111/j.1479-8425.2004.00119.x

By:

Yamanaka, Akihiro;
Muraki, Yo;
Tsujino, Natsuko;
Goto, Katsutoshi;
Sakurai, Takeshi

Publication type:

Article

The various impacts of the hepatitis C virus core protein upon hepatic oxidative stress after common bile duct ligation and partial hepatectomy.

Published in:

Redox Report, 2008, v. 13, n. 4, p. 172, doi. 10.1179/135100008X259277

By:

Chang, Ming-Yu;
Chen, Jeng-Chang;
Yeh, Chau-Ting;
Chiu, Cheng-Tang;
Lin, Deng-Yn;
Chang, Ming-Ling

Publication type:

Article

Precise 3D Localization of Intracerebral Implants Using a Simple Brain Clearing Method.

Published in:

Journal of Integrative Neuroscience, 2024, v. 23, n. 11, p. 1, doi. 10.31083/j.jin2311207

By:

Catanese, Julien;
Murakami, Tatsuya C.;
Catto, Adam;
Kenny, Paul J.;
Ibañez-Tallon, Ines

Publication type:

Article

Moderate-Intensity Treadmill Exercise Regulates GSK3α/β Activity in the Cortex and Hippocampus of APP/PS1 Transgenic Mice.

Published in:

Journal of Integrative Neuroscience, 2024, v. 23, n. 7, p. 1, doi. 10.31083/j.jin2307136

By:

Peng Han;
Boya Gu;
Lianwei Mu;
Ji-Guo Yu;
Li Zhao

Publication type:

Article

Icariin Inhibits Overexpression and Aggregation of α-Synuclein in A53T α-Synuclein Transgenic Mice by Regulating Parkin and PLK2.

Published in:

Journal of Integrative Neuroscience, 2023, v. 22, n. 6, p. 1, doi. 10.31083/j.jin2206166

By:

Denglei Ma;
Cong Shen;
Xu Zhang;
Lan Zhang;
Lin Li

Publication type:

Article

Curcumin ameliorates lipid metabolic disorder and cognitive dysfunction via the ABCA1 transmembrane transport system in APP/PS1 double transgenic mice.

Published in:

Journal of Integrative Neuroscience, 2021, v. 20, n. 4, p. 895, doi. 10.31083/j.jin2004091

By:

Mingyuan Tian;
Fanlin Zhou;
Zhipeng Teng;
Chen Wang;
Xiong Zhang;
Yangyang Wang;
Yu Li

Publication type:

Article

Correction to: Multilineage differentiation of muscle-derived stem cells from GFP transgenic mice.

Published in:

2022

By:

Ye, Chuan;
Li, Jiangwei;
He, Zixu;
Nin, Xu;
Zhang, Yi;
Shang, Xianwen;
Liu, Riguang;
Duan, Yiqiang

Publication type:

Correction Notice

Production of biologically active human factor IX-Fc fusion protein in the milk of transgenic mice.

Published in:

Biotechnology Letters, 2020, v. 42, n. 5, p. 717, doi. 10.1007/s10529-020-02808-1

By:

Yan, Hong;
Gong, Xiuli;
Xu, Miao;
Guo, Xinbing;
Chen, Yanwen;
Xue, Yan;
Zeng, Yitao;
Zeng, Fanyi

Publication type:

Article

Luciferase expression is driven by the promoter of fibroblast activation protein-α in murine pulmonary fibrosis.

Published in:

Biotechnology Letters, 2015, v. 37, n. 9, p. 1757, doi. 10.1007/s10529-015-1855-8

By:

Wenlong, Li;
Leilei, Yang;
Wei, Fan;
Yi, Chen;
Jing, Tian;
Lanzhi, Ma;
Bing, Liu;
Yang, Li;
Shaoxia, Wang;
Qiuxia, Fu;
Zeliang, Chen;
Zengming, Zhao

Publication type:

Article

Efficient stabilization of recombinant human coagulation factor VIII in the milk of transgenic mice using hFVIII and vWF co-expression vector transduction.

Published in:

Biotechnology Letters, 2015, v. 37, n. 6, p. 1187, doi. 10.1007/s10529-015-1793-5

By:

Ren, Xiaoye;
Gong, Xiuli;
Cai, Qin;
Guo, Xinbing;
Xu, Miao;
Ren, Zhaorui;
Zeng, Yitao

Publication type:

Article

Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse.

Published in:

Biotechnology Letters, 2014, v. 36, n. 6, p. 1179, doi. 10.1007/s10529-014-1473-x

By:

Auer, Dallas;
Sysa-Shah, Polina;
Bedja, Djahida;
Simmers, Jessica;
Pak, Evgenia;
Dutra, Amalia;
Cohn, Ronald;
Gabrielson, Kathleen;
Chakravarti, Aravinda;
Kapoor, Ashish

Publication type:

Article

The development of transgenic mice for the expression of large amounts of human lysozyme in milk.

Published in:

Biotechnology Letters, 2014, v. 36, n. 6, p. 1197, doi. 10.1007/s10529-014-1476-7

By:

Wu, Xiaojie;
Lin, Yanli;
Xi, Yongyi;
Shao, Zhenlu;
Zhou, Yanrong;
Liu, Fang;
Chen, Hongxing

Publication type:

Article

Expression of human transferrin can be regulated effectively by rabbit transferrin regulatory elements in transgenic mice.

Published in:

Biotechnology Letters, 2014, v. 36, n. 6, p. 1209, doi. 10.1007/s10529-014-1484-7

By:

Yan, Jingbin;
Gong, Xiuli;
Pan, Shubiao;
Guo, Xinbing;
Ren, Zhaorui;
Zeng, Yitao

Publication type:

Article

Generation of Rm21LG transgenic mice: a powerful tool to generate conditional overexpression of miR-21 that is involved in oncogenesis.

Published in:

Biotechnology Letters, 2014, v. 36, n. 1, p. 9, doi. 10.1007/s10529-013-1327-y

By:

Du, Tao;
Jia, Junshuang;
Lin, Xiaolin;
Xie, Raoying;
Li, Jing;
Xiao, Dong;
Xu, Kang

Publication type:

Article

Role of Wnt1 and Fzd1 in the spinal cord pathogenesis of amyotrophic lateral sclerosis-transgenic mice.

Published in:

Biotechnology Letters, 2013, v. 35, n. 8, p. 1199, doi. 10.1007/s10529-013-1199-1

By:

Wang, Shanshan;
Guan, Yingjun;
Chen, Yanchun;
Li, Xiaojin;
Zhang, Caixia;
Yu, Li;
Zhou, Fenghua;
Wang, Xin

Publication type:

Article

Establishment of transgenic mice carrying the gene for farnesyl pyrophosphate synthase.

Published in:

Biotechnology Letters, 2011, v. 33, n. 4, p. 687, doi. 10.1007/s10529-010-0493-4

By:

Jian Yang;
Jun-Chang Jiang;
Lei Guo;
Shen-Jiang Hu

Publication type:

Article

Bovine prolactin promotes the expression of human transferrin in the milk of transgenic mice.

Published in:

Biotechnology Letters, 2010, v. 32, n. 6, p. 787, doi. 10.1007/s10529-010-0232-x

By:

Song Li;
Xinbing Guo;
Xiuli Gong;
Miao Xu;
Jingbin Yan;
Ying Huang;
Zhaorui Ren

Publication type:

Article

Expression of functional recombinant human factor IX in milk of mice.

Published in:

Biotechnology Letters, 2008, v. 30, n. 12, p. 2063, doi. 10.1007/s10529-008-9818-y

By:

Lisauskas, Sharon F. C.;
Cunha, Nicolau B.;
Vianna, Giovanni R.;
Mendes, Érica A.;
Ramos, Gustavo L.;
Maranhão, Andréia Q.;
Brígido, Marcelo M.;
Almeida, Jussara O. S. C.;
Baptista, Heloisa A.;
Motta, Fabiana L. T.;
Pesquero, João B.;
Aragão, Francisco J. L.;
Rech, Elíbio L.

Publication type:

Article

The effect of soluble LAG-3 (CD223) treatment in fetal thymic organ culture.

Published in:

Biotechnology Letters, 2004, v. 26, n. 17, p. 1371, doi. 10.1023/B:BILE.0000045635.63873.96

By:

Taehoon Chun;
Hyun-Jung Byun;
Hee Chung;
Yong-Hoon Chung

Publication type:

Article

Diacylglycerol kinase α exacerbates cardiac injury after ischemia/reperfusion.

Published in:

Heart & Vessels, 2014, v. 29, n. 1, p. 110, doi. 10.1007/s00380-013-0366-6

By:

Sasaki, Toshiki;
Shishido, Tetsuro;
Kadowaki, Shinpei;
Kitahara, Tatsuro;
Suzuki, Satoshi;
Katoh, Shigehiko;
Funayama, Akira;
Netsu, Shunsuke;
Watanabe, Tetsu;
Goto, Kaoru;
Takeishi, Yasuchika;
Kubota, Isao

Publication type:

Article

Prolonged survival of rat whole-limb allografts treated with cyclophosphamide, granulocyte colony-stimulation factor and FK506.

Published in:

Transplant International, 2006, v. 19, n. 10, p. 840, doi. 10.1111/j.1432-2277.2006.00362.x

By:

Muramatsu, Keiichi;
You Xin, Song;
Hashimoto, Takahiro;
Matsunaga, Tsunemitsu;
Gondo, Toshikazu;
Taguchi, Toshihiko

Publication type:

Article

A novel model of allograft rejection: immune reconstitution of Rag-1 recipients with 2C transgenic T-cell receptor lymphocytes.

Published in:

Transplant International, 2005, v. 18, n. 1, p. 101, doi. 10.1111/j.1432-2277.2004.00012.x

By:

Ninova, Dora;
Dean, Patrick G.;
Deeds, Michael;
Stegall, Mark D.

Publication type:

Article

Systemic inflammation enhances metastatic growth in a syngeneic neuroblastoma mouse model.

Published in:

Pediatric Surgery International, 2024, v. 40, n. 1, p. 1, doi. 10.1007/s00383-024-05788-9

By:

Mimura, Kazuya;
Fumino, Shigehisa;
Yamashi, Kodai;
Iguchi, Masafumi;
Inoue, Maho;
Takayama, Shohei;
Kim, Kiyokazu;
Aoi, Shigeyoshi;
Tajiri, Tatsuro;
Ono, Shigeru

Publication type:

Article