Works matching DE "DRUG target"
Results: 5000
Proteomic Analysis of Transbronchial Biopsy Tissue Reveals a Distinct Proteome and Mechanistic Pathways in High-Grade Eosinophilic Inflammation After Lung Transplantation.
- Published in:
- 2025
- By:
- Publication type:
- Letter
Pan-cancer characterization of C–C motif chemokine ligand 5 (CCL5) identifies its role as biomarker and therapeutic target.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02004-5
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- Publication type:
- Article
Histone H3 lysine 9 tri-methylation is associated with pterygium.
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- BMC Ophthalmology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12886-025-03939-7
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- Publication type:
- Article
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities.
- Published in:
- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56695-z
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- Publication type:
- Article
A Systematic Review of the Expression Pattern of Long Non-Coding RNAs SNHG5, SNHG17, and SNHG26 in Human Solid Tumors.
- Published in:
- Reviews in Clinical Medicine, 2024, v. 11, n. 4, p. 22, doi. 10.22038/rcm.2024.82201.1504
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- Publication type:
- Article
Spinal HDAC2 Influences the Development of Chronic Pancreatitis-Related Pain through mGluR2.
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- Journal of Evolutionary Biochemistry & Physiology, 2025, v. 61, n. 1, p. 358, doi. 10.1134/S0022093024600568
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- Publication type:
- Article
Time to change guidelines? Suboptimal glycemic control measures by CGM associated with cystic fibrosis exacerbations despite adequate HbA1c.
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- Acta Diabetologica, 2025, v. 62, n. 3, p. 429, doi. 10.1007/s00592-025-02457-8
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- Publication type:
- Article
Genomic diversity of mcr-carrying plasmids and the role of type IV secretion systems in IncI2 plasmids conjugation.
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- Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07748-y
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- Publication type:
- Article
MurG as a potential target of quercetin in Staphylococcus aureus supported by evidence from subtractive proteomics and molecular dynamics.
- Published in:
- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-90395-4
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- Publication type:
- Article
The role of telomere and telomerase in cancer and novel therapeutic target: narrative review.
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- Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1542930
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- Publication type:
- Article
A high-throughput screening platform to identify MYCN expression inhibitors for liver cancer therapy.
- Published in:
- Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1486671
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- Publication type:
- Article
Targeting Spinal Interneurons for Respiratory Recovery After Spinal Cord Injury.
- Published in:
- Cells (2073-4409), 2025, v. 14, n. 4, p. 288, doi. 10.3390/cells14040288
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- Publication type:
- Article
Molecular Insights in Endometrial Stromal Sarcomas: Exploring New Targets for Novel Therapeutic Approaches.
- Published in:
- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 265, doi. 10.3390/biom15020265
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- Publication type:
- Article
Modulating PAK1: Accessory Proteins as Promising Therapeutic Targets.
- Published in:
- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 242, doi. 10.3390/biom15020242
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- Publication type:
- Article
Determining Ligand Binding and Specificity Within the β 2 -Integrin Family with a Novel Assay Platform.
- Published in:
- Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 238, doi. 10.3390/biom15020238
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- Publication type:
- Article
Unravelling the neuroimmune nexus: insights into epilepsy pathology and the role of S100b protein in brain-gut axis modulation: a literature review.
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- Postgraduate Medical Journal, 2025, v. 101, n. 1193, p. 181, doi. 10.1093/postmj/qgae125
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- Publication type:
- Article
Brain Glucose Hypometabolism and Brain Iron Accumulation as Therapeutic Targets for Alzheimer's Disease and Other CNS Disorders.
- Published in:
- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 271, doi. 10.3390/ph18020271
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- Publication type:
- Article
Repeated-Dose Toxicity of Lauric Acid and Its Preventive Effect Against Tracheal Hyper-Responsiveness in Wistar Rats with Possible In Silico Molecular Targets.
- Published in:
- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 221, doi. 10.3390/ph18020221
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- Publication type:
- Article
Narrative Review of Genetic and Immunological Mechanisms Involved in the Pathogenesis of Kimura's Disease: New Therapeutic Targets.
- Published in:
- Genes, 2025, v. 16, n. 2, p. 194, doi. 10.3390/genes16020194
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- Publication type:
- Article
Fabrication of protein–inorganic biohybrid as an imageable drug delivery system comprising transferrin, green fluorescent protein, and copper phosphate.
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- Biotechnology & Bioprocess Engineering, 2025, v. 30, n. 1, p. 70, doi. 10.1007/s12257-024-00148-9
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- Publication type:
- Article
CANDI: a web server for predicting molecular targets and pathways of cannabis-based therapeutics.
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- Journal of Cannabis Research, 2025, v. 7, n. 1, p. 1, doi. 10.1186/s42238-025-00268-w
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- Publication type:
- Article
Antimicrobial Steroids from Poisonous Mushroom Gymnopilus orientispectabilis and Their Molecular Docking Studies.
- Published in:
- Separations (2297-8739), 2025, v. 12, n. 2, p. 23, doi. 10.3390/separations12020023
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- Publication type:
- Article
Unveiling the effects of GSK126 on osteosarcoma cells implications for apoptosis, autophagy, and cellular migration.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02010-7
- By:
- Publication type:
- Article
Psoriasis Treatments: Emerging Roles and Future Prospects of MicroRNAs.
- Published in:
- Non-Coding RNA, 2025, v. 11, n. 1, p. 16, doi. 10.3390/ncrna11010016
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- Publication type:
- Article
Identification of Potential Therapeutic Targets for Sensorineural Hearing Loss and Evaluation of Drug Development Potential Using Mendelian Randomization Analysis.
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- Bioengineering (Basel), 2025, v. 12, n. 2, p. 126, doi. 10.3390/bioengineering12020126
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- Publication type:
- Article
The role and application of bioinformatics techniques and tools in drug discovery.
- Published in:
- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1547131
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- Publication type:
- Article
The Diagnostic Significance of SLC26A2 and Its Potential Role in Ulcerative Colitis.
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- Biomedicines, 2025, v. 13, n. 2, p. 461, doi. 10.3390/biomedicines13020461
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- Publication type:
- Article
Clinical Electrophysiology and Mathematical Modeling for Precision Diagnosis of Infertility.
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- Biomedicines, 2025, v. 13, n. 2, p. 250, doi. 10.3390/biomedicines13020250
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- Publication type:
- Article
The metabolic role of lactate dehydrogenase in the growth of diffuse large B cell lymphoma.
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- Annals of Hematology, 2025, v. 104, n. 1, p. 545, doi. 10.1007/s00277-024-06083-2
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- Publication type:
- Article
Impact of histopathological subtypes on invasive lung adenocarcinoma: from epidemiology to tumour microenvironment to therapeutic strategies.
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- World Journal of Surgical Oncology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12957-025-03701-9
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- Publication type:
- Article
Combining Subtractive Genomics with Computer-Aided Drug Discovery Techniques to Effectively Target S. sputigena in Periodontitis.
- Published in:
- Computation, 2025, v. 13, n. 2, p. 34, doi. 10.3390/computation13020034
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- Publication type:
- Article
RIPK1 in necroptosis and recent progress in related pharmaceutics.
- Published in:
- Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1480027
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- Publication type:
- Article
Dual graph-embedded fusion network for predicting potential microbe-disease associations with sequence learning.
- Published in:
- Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1511521
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- Publication type:
- Article
Current and future therapeutic options for chronic hepatitis D virus infection.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2024.1382017
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- Publication type:
- Article
Dual-function regulator MexL as a target to control phenazines production and pathogenesis of Pseudomonas aeruginosa.
- Published in:
- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57294-8
- By:
- Publication type:
- Article
The Interplay Between Immunity, Inflammation and Endothelial Dysfunction.
- Published in:
- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1708, doi. 10.3390/ijms26041708
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- Publication type:
- Article
Circular RNA-Drug Association Prediction Based on Multi-Scale Convolutional Neural Networks and Adversarial Autoencoders.
- Published in:
- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1509, doi. 10.3390/ijms26041509
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- Publication type:
- Article
Role of Human DNA Ligases in Mediating Pharmacological Activities of Flavonoids.
- Published in:
- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1456, doi. 10.3390/ijms26041456
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- Publication type:
- Article
Mint3 as a Molecular Target Activated in the Early Stage of Hepatocarcinogenesis.
- Published in:
- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1430, doi. 10.3390/ijms26041430
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- Publication type:
- Article
Design, Synthesis and Bioactive Evaluation of Topo I/ c-MYC Dual Inhibitors to Inhibit Oral Cancer via Regulating the PI3K/AKT/NF-κB Signaling Pathway.
- Published in:
- Molecules, 2025, v. 30, n. 4, p. 894, doi. 10.3390/molecules30040894
- By:
- Publication type:
- Article
Playing Around the Coumarin Core in the Discovery of Multimodal Compounds Directed at Alzheimer's-Related Targets: A Recent Literature Overview.
- Published in:
- Molecules, 2025, v. 30, n. 4, p. 891, doi. 10.3390/molecules30040891
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- Publication type:
- Article
Elucidating the role of genetically determined metabolites in Diabetic Retinopathy: insights from a mendelian randomization analysis.
- Published in:
- Acta Diabetologica, 2025, v. 62, n. 2, p. 193, doi. 10.1007/s00592-024-02345-7
- By:
- Publication type:
- Article
SGLT-2 inhibitors are beneficial in reducing the risk of thyroid cancer: findings from a Mendelian randomization study.
- Published in:
- Acta Diabetologica, 2025, v. 62, n. 2, p. 185, doi. 10.1007/s00592-024-02344-8
- By:
- Publication type:
- Article
Intrathymic Hemagioma: A Challenging Case Report with Special Focus on the Importance of Its Multidisciplinary Approach.
- Published in:
- Pediatric Reports, 2025, v. 17, n. 1, p. 13, doi. 10.3390/pediatric17010013
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- Publication type:
- Article
Exploring BIRC family genes as prognostic biomarkers and therapeutic targets in prostate cancer.
- Published in:
- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02002-7
- By:
- Publication type:
- Article
mRNA stability fine-tunes gene expression in the developing cortex to control neurogenesis.
- Published in:
- PLoS Biology, 2025, v. 23, n. 2, p. 1, doi. 10.1371/journal.pbio.3003031
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- Publication type:
- Article
Niche-specific metabolic phenotypes can be used to identify antimicrobial targets in pathogens.
- Published in:
- PLoS Biology, 2024, v. 22, n. 11, p. 1, doi. 10.1371/journal.pbio.3002907
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- Publication type:
- Article
Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.
- Published in:
- PLoS Biology, 2024, v. 22, n. 7, p. 1, doi. 10.1371/journal.pbio.3002673
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- Publication type:
- Article
Mapping mutational fitness effects across the coxsackievirus B3 proteome reveals distinct profiles of mutation tolerability.
- Published in:
- PLoS Biology, 2024, v. 22, n. 7, p. 1, doi. 10.1371/journal.pbio.3002709
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- Publication type:
- Article
New molecular targets in canine hemangiosarcoma—Comparative review and future of the precision medicine.
- Published in:
- Veterinary & Comparative Oncology, 2023, v. 21, n. 3, p. 357, doi. 10.1111/vco.12917
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- Publication type:
- Article