Works matching IS 1663-9812 AND DT 2025

Results: 1504

Deciphering metabolic disease mechanisms for natural medicine discovery via graph autoencoders.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1594186

By:

Liao, Qingquan;
Zhao, Wei;
Wang, Zhan;
Xu, Lei;
Yang, Kun;
Liu, Xinxin;
Zhang, Lichao

Publication type:

Article

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592909

By:

Delcourte, Sarah;
Bouloufa, Amel;
Rovera, Renaud;
Brunet, Elie;
Le, Hiep D.;
Williams, April E.;
Panda, Satchidananda;
Azmani, Rihab;
Raineteau, Olivier;
Dkhissi-Benyahya, Ouria;
Haddjeri, Nasser

Publication type:

Article

LL37 promotes angiogenesis: a potential therapeutic strategy for lower limb ischemic diseases.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1587351

By:

Yang, Yingying;
Wu, Gang;
Wang, Yini;
Mao, Qiancheng;
Zhang, Dongxu;
Wu, Jitao

Publication type:

Article

Efficacy, safety, and tolerability of soticlestat (TAK-935) as adjunctive therapy in pediatric patients with dravet syndrome and Lennox–Gastaut syndrome: a meta-analysis of 3 randomized controlled trials.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1586098

By:

Lanlan, Zhang;
Nana, Jiang;
Chengzhong, Wang

Publication type:

Article

Corrigendum: Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties.

Published in:

2025

By:

Muslim, Wisam Taher;
Mohammad, Layth Jasim;
Naji, Munaf M.;
Karimi, Isaac;
Al-Sabti, Matheel D.;
Jabir, Majid;
Najm, Mazin A. A.;
Schiöth, Helgi B.

Publication type:

Correction Notice

Magnolol and honokiol: potential lead compounds for the new drug discovery in treating autoimmune diseases.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1578971

By:

Lin, Xian;
Chen, Jian

Publication type:

Article

mTOR-mediated nutrient sensing and oxidative stress pathways regulate autophagy: a key mechanism for traditional Chinese medicine to improve diabetic kidney disease.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1578400

By:

Li, Liu;
Zou, Junju;
Zhou, Tongyi;
Liu, Xiu;
Tan, Danni;
Xiang, Qin;
Yu, Rong

Publication type:

Article

An off-target effect of class A CpG-oligonucleotides on suppressing the cyclic GMP-AMP synthase signaling in fibroblastic reticular cells.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1576151

By:

Jayakumar, Preethi;
Jiang, Ting;
Huang, Hai;
Deng, Meihong

Publication type:

Article

Astragaloside IV as a promising therapeutic agent for liver diseases: current landscape and future perspectives.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1574154

By:

Chen, Chunyan;
Bu, Xiaolan;
Deng, Liping;
Xia, Jiayan;
Wang, Xinming;
Chen, Li;
Li, Wen;
Huang, Jie;
Chen, Qixiang;
Wang, Cheng

Publication type:

Article

Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1565451

By:

Yang, Chengyu;
Xu, Ya;
Gong, Fenfang;
Li, Silu;
Zhan, Huang;
Huang, Zhixuan;
Wang, Maolin;
Li, Hui;
Huang, Hengjun

Publication type:

Article

Pharmacokinetics and bioequivalence assessment of two prucalopride formulations in healthy Chinese women: a randomized, open-label, two-period, two-sequence, self-crossover study.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1562692

By:

Huang, Xiangxin;
Wang, Ying;
Li, Bei;
Shen, Xiaoqun;
Tao, Xuexia;
Zheng, Wenwen;
Luo, Qi;
Xiong, Lei;
Wang, Lin;
Cai, Shufan

Publication type:

Article

Tetramethylpyrazine alleviates acute pancreatitis inflammation by inhibiting pyroptosis via the NRF2 pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1557681

By:

Li, Huangen;
Gao, Yi;
Huang, Minglian;
Zhang, Hongling;
Wu, Qingqing;
Huang, Youpei;
Ye, Xiaotong;
Chen, Weiwen

Publication type:

Article

Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1555859

By:

Ouyang, Dan;
Jiang, Xiao;
Wang, Hui;
Xu, Ma Li;
Qi, Hang;
Li, Xin Hui;
Cao, Jian Zhong

Publication type:

Article

Volatile oil of Acori tatarinowii rhizoma : potential candidate drugs for mitigating dementia.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1552801

By:

Bu, Yifan;
Li, Songzhe;
Ye, Ting;
Wang, Yuqing;
Song, Mingrong;
Chen, Jing

Publication type:

Article

PDP1 related ferroptosis risk signature indicates distinct immune microenvironment and prognosis of breast cancer patients.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1551325

By:

Wang, Yufeng;
Dang, Huifen;
Zhu, Gongjian;
Tian, Yingxia

Publication type:

Article

Clusterin ameliorates diabetic atherosclerosis by suppressing macrophage pyroptosis and activation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1536132

By:

Xuan, Lingling;
Ren, Lulu;
Kang, Xiaoxu;
Chang, Rui;
Zhang, Wen;
Gong, Lili;
Liu, Lihong

Publication type:

Article

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534101

By:

Valenti, Ornella;
Rekawek, Katarzyna Anna;
Wieser, Sophie;
Bulut, Hilal;
Scholze, Petra;
Boehm, Stefan

Publication type:

Article

Comprehensive characterisation of the active ingredients of Smilax glabra Roxb based on chemical fingerprinting, metabolic fingerprinting and pharmacodynamic fingerprinting.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1519054

By:

Shi, Wenqing;
Jia, Mengqi;
Li, Xiao;
Zhao, Xin;
Wang, Chenxi;
Fan, Guorong;
Lou, Yuefen

Publication type:

Article

Targeting the PI3K/AKT/mTOR pathway in lung cancer: mechanisms and therapeutic targeting.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1516583

By:

Qiang, Min;
Chen, Zhe;
Liu, Hongyang;
Dong, Junxue;
Gong, Kejian;
Zhang, Xinjun;
Huo, Peng;
Zhu, Jingjun;
Shao, Yifeng;
Ma, Jinazun;
Zhang, Bowei;
Liu, Wei;
Tang, Mingbo

Publication type:

Article

Curcumin as a potential therapeutic agent for Parkinson's disease: a systematic review.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1593191

By:

Chang, Yu-Hsien

Publication type:

Article

Editorial: Mobilization of hematopoietic cells from the bone marrow to the peripheral blood: Challenges and new therapeutic targets.

Published in:

2025

By:

Szade, Agata;
Gulati, Gunsagar S.;
Czechowicz, Agnieszka D.

Publication type:

Editorial

Adverse reactions of four multi-targeted tyrosine kinase inhibitors: a descriptive analysis of the WHO-VigiAccess database.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1585862

By:

Li, Lijun;
Bai, Jiayu;
Wen, Xuelong;
Zeng, Xuefan

Publication type:

Article

Gut microbiota-mitochondrial crosstalk in obesity: novel mechanistic insights and therapeutic strategies with traditional Chinese medicine.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1574887

By:

Wen, Lingmiao;
Yang, Kun;
Wang, Jiexin;
Zhou, Hang;
Ding, Weijun

Publication type:

Article

Gaussian white noise stimulation as an alternative method to excite sensory neurons.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1561905

By:

Losgott, Thomas;
Schicker, Klaus W.;
Hilber, Karlheinz;
Boehm, Stefan;
Salzer, Isabella

Publication type:

Article

Sodium aescinate promotes apoptosis of pancreatic stellate cells and alleviates pancreatic fibrosis by inhibiting the PI3K/Akt/FOXO1 signaling pathways.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1554260

By:

Wang, Qing-Yun;
Xu, Bai-Yan;
Wang, Yi;
Lin, Yan-Mei;
Zheng, Lin-Fu;
Liu, Gang;
Li, Da-Zhou;
Jiang, Chuan-Shen;
Wang, Wen;
Zeng, Xiang-Peng

Publication type:

Article

GluN2B influences the progression of status epilepticus by modulating calcium ion homeostasis through its interaction with CaMKIIα.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1550879

By:

Zhang, Lin;
Meng, Youshi;
Liu, Chaoning;
Wei, Lei;
Lu, Yuling;
Zheng, Shouhuan;
Zou, Donghua;
Wu, Yuan

Publication type:

Article

The efficacy of aminosalicylates in acute radiation enteritis: a systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1544981

By:

Wu, Zhendong;
Ni, Chuyan;
Ye, Zhen;
Xia, Zhongsheng;
Li, Li;
Yu, Zhong;
Tang, Song;
Lin, Ying;
Zhong, Wa

Publication type:

Article

Metformin in gynecological disorders: pathogenic insights and therapeutic implications.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1526709

By:

Nie, Ping;
Wang, Minghua;
Mo, Yan;
Zhou, Hong;
Zha, Qingbing;
Lash, Gendie E.;
Li, Ping

Publication type:

Article

RNF180 weakened the lipid droplet formation and subsequent chemoresistance by destabilizing ACC1 and ACLY in esophageal cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1525431

By:

Li, Ning;
Shen, Dao-Fu;
Yin, Nan-Chang;
Cui, Zheng-Guo;
Zheng, Hua-Chuan

Publication type:

Article

Therapeutic potential of natural arginase modulators: mechanisms, challenges, and future directions.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1514400

By:

Li, Ting;
Wang, Jieying;
Wang, Huan;
Zhang, Bowei;
Duan, Lijuan

Publication type:

Article

Targeting fibroblast growth factor (FGF)-21: a promising strategy for metabolic dysfunction-associated steatotic liver disease treatment.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1510322

By:

Cui, Xinyue;
Sun, Quanhao;
Wang, Haiqiang

Publication type:

Article

Effect of propinox and pinaverium bromide on ex vivo colonic motor patterns and their synergistic effect with hyoscine butyl bromide.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1491123

By:

Traserra, Sara;
Alcalá-González, Luis Gerardo;
Barber, Claudia;
Landolfi, Stefania;
Malagelada, Carolina;
Lange, Robert;
Appelqvist, Terence;
Corsetti, Maura;
Jimenez, Marcel

Publication type:

Article

Rosa roxburghii Tratt juice ameliorates metabolic disorder in arsenicosis patients based on the analysis of untargeted plasma metabolomics.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1488113

By:

Yang, Luming;
Zhu, Kai;
Wang, Wenjuan;
Sun, Baofei;
Luo, Peng;
Zhang, Aihua

Publication type:

Article

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1511627

By:

Muslim, Wisam Taher;
Mohammad, Layth Jasim;
Naji, Munaf M.;
Karimi, Isaac;
Al-Sabti, Matheel D.;
Jabir, Majid;
Najm, Mazin A. A.;
Schiöth, Helgi B.

Publication type:

Article

Polydatin attenuates Alzheimer's disease induced by aluminum chloride in rats: evidence for its antioxidant and anti-inflammatory effects.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1574323

By:

Zarneshan, Seyede Nazanin;
Fakhri, Sajad;
Kiani, Amir;
Abbaszadeh, Fatemeh;
Hosseini, Seyede Zahra;
Mohammadi-Noori, Ehsan;
Echeverría, Javier

Publication type:

Article

Editorial: Multi-omics application in exploring potential biomarkers targeting resistance of anti-cancer drugs.

Published in:

2025

By:

Wang, Huan;
Xie, Jindong;
Tian, Zhi;
Allen-Gipson, Diane S.;
Tang, Hailin

Publication type:

Editorial

LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592846

By:

Xu, Leidi;
Zhang, Yibo;
Xing, Liangliang;
Zhou, Ying;
Chang, Ning;
Xi, Hangtian;
Xu, Xiangrui;
Zhang, Jian

Publication type:

Article

Advances in plant essential oils and drug delivery systems for skincare.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1578280

By:

Yihan, Wang;
Jinjin, Dou;
Yingqi, Wang;
Guanai, Mu;
Xiwu, Zhang

Publication type:

Article

Targeting PCNA/PARP1 axis inhibits the malignant progression of hepatocellular carcinoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1571786

By:

Li, Jipin;
Yong, Tao;
Chen, Yali;
Zeng, Tingyu;
Zhang, Kaifeng;
Wang, Shuping;
Zhang, Youcheng

Publication type:

Article

NLRP3 inflammasome as a therapeutic target in doxorubicin-induced cardiotoxicity: role of phytochemicals.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1567312

By:

Zhao, Xiao-Peng;
Duan, Lian;
Zhao, Qian-Ru;
Lv, Xing;
Tian, Nai-Yuan;
Yang, Sheng-Lei;
Dong, Kun

Publication type:

Article

α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1566311

By:

Bai, Xue;
Zhang, Ziqian;
Zhang, Miao;
Xu, Jiaojiao;
Dong, Keting;
Du, Qian;
Chen, Lei;
Ma, Ping;
Yang, Jianhong

Publication type:

Article

Analysis of sedative-hypnotic drug use trends in children and adolescents (2018–2023): a study based on outpatient prescription data from a general hospital.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1563580

By:

Qingyu, Zhang;
Wenqing, Jiang;
Le, Ma;
Yanbin, Hou;
Pingping, Miao;
Chen, Lin;
Jiaxin, Mao;
Ni, Dai;
Dalu, Yang;
Kanzhen, Tong;
Junting, Su;
Zhenzhen, Zhu;
Liemin, Ruan;
Yunxin, Ji

Publication type:

Article

Different routes the same destination: a comparative study of antitrust regulation for pharmaceutical industry in the United States and China.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1557876

By:

Weng, Jie;
Liu, Nailiang

Publication type:

Article

The pharmacokinetics and Concentration-QTc analysis of a new etomidate analog ET-26-HCl: a phase I trial in healthy Chinese subjects.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534717

By:

He, Kun;
Zhang, Wenyu;
Kong, Xiangran;
Li, Lize;
Diao, Lei;
Wen, Qing;
Su, Guohai;
Yang, Xiaoran;
Zhao, Hongyan

Publication type:

Article

Methyltransferase-like 3 is a target for the diagnose and therapy of clear cell renal carcinoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534655

By:

Xiao, Dongqiong;
Su, Xiaojuan

Publication type:

Article

SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1532658

By:

Wang, Xiangjun;
Yang, Chuanxin;
Liu, Yangming;
Wang, Jian

Publication type:

Article

Bee venom ameliorates gentamicin-induced kidney injury by restoring renal aquaporins and enhancing antioxidant and anti-inflammatory activities in rats.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1525529

By:

Abdelrahaman, Doaa;
Shanab, Obeid;
Abdeen, Ahmed;
Abdelkader, Afaf;
Elazab, Khalid M.;
Kouriem, Hagar;
Maher, Zainab M.;
Abu-Almakarem, Amal S.;
Mohamed, Mohamed E.;
Elbastawisy, Yasser M.;
Elsehrawy, Mohamed G.;
Badawy, Abdelnaser A.;
Mokhtar, Naglaa;
Mojaddidi, Moaz A.;
Zakari, Madaniah O.;
Ibrahim, Samah F.;
Abdelhady, Dania;
Mostafa, Laila

Publication type:

Article

The efficacy and safety of Chinese herbal medicine Shugan Sanjie decoction in the treatment of uterine fibroids: a systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1508015

By:

Zhang, Yang;
Wei, Junfan;
Gao, Chanchan;
Feng, Shenyang;
Wang, Haiying;
Chai, Junjie;
Zhu, Yini;
Yuan, Yuan;
Ren, Lirong

Publication type:

Article

The Wnt/β-catenin signaling pathway in colorectal cancer: mechanism and intervention of traditional Chinese medicine and chemical compound.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1560714

By:

Zeng, Sha;
Wang, Juan;
Shi, Zhengrong;
Zhao, Hui;
Gao, Jingxing;
Li, Jinxiu

Publication type:

Article

Exploring disulfiram mechanisms in renal fibrosis: insights from biological data and computational approaches.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1480732

By:

Patil, Vishal S.;
Patil, Chandragouda R.;
Patel, Harun M.;
Kumar, Anoop

Publication type:

Article