Works matching DE "DRUG resistance in cancer cells"

Results: 5000

Evaluating the multitargeted potency of Pixuvri against cell cycle regulation proteins in cervical cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1598883

By:

Alshehri, Mohammed Ali;
Alahdal, Hadil;
Aloqbi, Akram Ahmed;
Shakoori, Afnan Mohammed;
Sindi, Ghadir;
Bagadood, Rehab M.;
Alsaffar, Nida;
Alobaidy, Mohammad Ahmad;
Alrabiah, Noof Abdulrahman;
Khursheed, Md;
Tuwaijri, Abeer Al

Publication type:

Article

Advancing targeted therapy for colorectal cancer: harnessing ligand-directed enzyme prodrug therapy for highly specific interventions.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1570712

By:

Al-Jaber, Hend;
Biswas, Kabir H.;
Al-Mansoori, Layla

Publication type:

Article

靶向阻断 Sphk1促进奥沙利铂的抗结肠癌作用.

Published in:

Journal of Xi'an Jiaotong University (Medical Sciences), 2025, v. 46, n. 3, p. 435, doi. 10.7652/jdyxb202503008

By:

李政;
曹洁玮;
刘彬

Publication type:

Article

SPARC Promotes Aerobic Glycolysis and 5‐Fluorouracil Resistance in Colorectal Cancer Through the STAT3/HK2 Axis.

Published in:

Cancer Medicine, 2025, v. 14, n. 11, p. 1, doi. 10.1002/cam4.70972

By:

Xiang, Jingrong;
Zhang, Huan;
Shen, Kanger;
Feng, Jie;
Yang, Kexi;
Shi, Tongguo;
Xi, Qinhua

Publication type:

Article

The role and mechanism of fatty acid oxidation in cancer drug resistance.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02554-1

By:

Lei, Yun;
Cai, Shuang;
Zhang, Jia-Kui;
Ding, Si-Qi;
Zhang, Zhan-He;
Zhang, Chun-Dong;
Dai, Dong-Qiu;
Li, Yong-Shuang

Publication type:

Article

Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer.

Published in:

Cancer Nanotechnology (1868-6958), 2025, v. 16, n. 1, p. 1, doi. 10.1186/s12645-025-00329-y

By:

Li, Quanjiang;
Xie, Yufeng;
Zhang, Wanting;
Peng, Jun;
Deng, Zhujie;
Tian, Rui;
Kuang, Xiubin;
Xie, Bin;
Huang, Chen;
Zhao, Yu;
Yuan, Zhengqiang

Publication type:

Article

Potential application of the wolly mouse in future research.

Published in:

2025

By:

Khanra, Supriya;
Datta, Aastha;
Charan, Shiv;
Kulkarni, Rutweek;
Prakash, Ajay;
Medhi, Bikash

Publication type:

Editorial

Enhancer RNAs profiling in colorectal cancer liver metastases reveals novel molecular subtypes with prognostic and therapeutic relevance.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02879-4

By:

Bu, Xiaoyun;
Wen, Dongsheng;
Zhou, Tiejun;
Xiao, Lei;
Zhang, Zhiqing;
Zhao, Xingshuai;
Hu, Yingbin

Publication type:

Article

Development of a Novel Biomarker Platform for Profiling Key Protein–Protein Interactions to Predict the Efficacy of BH3-Mimetic Drugs.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1852, doi. 10.3390/cancers17111852

By:

Kinloch, Andrew J.;
Rahman, Faiyaz;
Karakas, Bahriye;
Shahid, Muhammad;
Lim, Bora;
Bouley, Stephanie J.;
Walker, James A.;
Lee, Erinna F.;
Fairlie, Walter D.;
Kelly, Kevin R.;
Cardone, Michael H.

Publication type:

Article

Phase Ia/Ib Study of Afatinib with Capecitabine in Patients with Refractory Solid Tumors and Pancreaticobiliary Cancers.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1830, doi. 10.3390/cancers17111830

By:

King, Gentry G.;
Baker, Kelsey K.;
Coveler, Andrew L.;
Harris, William P.;
Cohen, Stacey A.;
Shankaran, Veena;
Zhen, David B.;
Safyan, Rachael A.;
Lee, Hannah H.;
Alidina, Annie;
Hensel, Jeniece;
Hibbert, Reina;
Durm, Greg A.;
LaFary, Yvonne C.;
Younger, Anne;
Kugel, Sita;
Collisson, Eric;
Konnick, Eric Q.;
Redman, Mary W.;
Schneider, Bryan P.

Publication type:

Article

Systemic Therapeutic Options in Radioiodine-Refractory Differentiated Thyroid Cancer: Current Indications and Optimal Timing.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1800, doi. 10.3390/cancers17111800

By:

Díaz Vico, Tamara;
Martínez-Amores Martínez, Brezo;
Mihic Góngora, Luka;
Jiménez-Fonseca, Paula;
Peinado Martín, Paloma;
Grao Torrente, Irene;
García Muñoz-Nájar, Alejandro;
Durán-Poveda, Manuel

Publication type:

Article

The Roles of STAT3 and STAT5 in Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1781, doi. 10.3390/cancers17111781

By:

Temple, Alexandra E.;
Walker, Sarah R.

Publication type:

Article

Docetaxel Administration via Novel Hierarchical Nanoparticle Reduces Proinflammatory Cytokine Levels in Prostate Cancer Cells.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1758, doi. 10.3390/cancers17111758

By:

Aalinkeel, Ravikumar;
Sharma, Satish;
Mahajan, Supriya D.;
Prasad, Paras N.;
Schwartz, Stanley A.

Publication type:

Article

Advances in Isorhamnetin Treatment of Malignant Tumors: Mechanisms and Applications.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1853, doi. 10.3390/nu17111853

By:

Mei, Chen;
Liu, Ying;
Lyu, Xueze;
Jiang, Zhaoling;
Liu, Zhenyi;
Zhi, Yan;
Xu, Xiaolong;
Wang, Hongjun

Publication type:

Article

Glucosylceramide Synthase, a Key Enzyme in Sphingolipid Metabolism, Regulates Expression of Genes Accounting for Cancer Drug Resistance.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5112, doi. 10.3390/ijms26115112

By:

Mostaq, Md Saqline;
Kang, Lin;
Patwardhan, Gauri A.;
Zhao, Yunfeng;
Shi, Runhua;
Liu, Yong-Yu

Publication type:

Article

AKT1 and CTNNB1 mutations as drivers of paclitaxel resistance in breast cancer cells.

Published in:

Oncology Letters, 2025, v. 30, n. 1, p. N.PAG, doi. 10.3892/ol.2025.15070

By:

Altiparmak-Ulbegi, Gulsum;
Hasbal-Celikok, Gozde;
Aksoy-Sagirli, Pinar

Publication type:

Article

Chlorogenic Acid Enhances Beta‐Lapachone‐Induced Cell Death by Suppressing Autophagy in NQO1‐Positive Cancer Cells.

Published in:

Cell Biology International, 2025, v. 49, n. 5, p. 555, doi. 10.1002/cbin.70006

By:

Zada, Sahib;
Bahar, Md Entaz;
Kim, Wanil;
Kim, Deok Ryong

Publication type:

Article

Automatic target-seeking nanoparticle inhibiting orthotopic drug-resistant colon cancer and liver metastases via regulating cancer cell adhesion and proliferation.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03422-x

By:

Bai, Shaobo;
Sun, Yang;
Liu, Miao;
Cheng, Ying;
Ji, Qifeng;
Zhang, Bangle;
Yang, Zhifu;
Zhou, Siyuan;
Liu, Daozhou

Publication type:

Article

Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00788-w

By:

Zhang, Li;
Yang, Yang;
Li, Yanchu;
Wang, Chenyu;
Bian, Chenbin;
Wang, Hongbin;
Wang, Feng

Publication type:

Article

Hydrogen Sulfide Expression May Affect Ovarian Cancer Progression and Drug Resistance.

Published in:

International Journal of Women's Health, 2025, v. 17, p. 1533, doi. 10.2147/IJWH.S515836

By:

Zhu, Qiong;
Liu, Yi;
Zhou, Juan;
Tan, Miduo;
Xue, Yaxin;
Tao, Yin

Publication type:

Article

Immunotherapies versus small-molecule therapies of cancers with RAS oncogene mutations.

Published in:

Polish Journal of Allergology / Alergologia Polska, 2025, v. 12, n. 2, p. 111, doi. 10.5114/pja.2025.148075

By:

Rieske, Piotr

Publication type:

Article

Combination strategies of gut microbiota in cancer therapy through metabolic reprogramming and immune remodeling.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02275-z

By:

Wang, Lixuan;
Jiang, Weibo;
Yang, Manshi;
Danzeng, Quezhu;
Liu, Shiyu;
Cui, Mengying

Publication type:

Article

Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab-resistant HER2-positive breast cancer.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103953

By:

Yijia Hua;
Ningjun Duan;
Chunxiao Sun;
Fan Yang;
Min Tian;
Yanting Sun;
Shuhan Zhao;
Jue Gong;
Qian Liu;
Xiang Huang;
Yan Liang;
Ziyi Fu;
Wei Li;
Yongmei Yin

Publication type:

Article

EZH2 promotes chemoresistance in colorectal cancer by inhibiting autophagy through NRP1 suppression.

Published in:

Biochemical Journal, 2025, v. 482, n. 10, p. 569, doi. 10.1042/bcj20240607

By:

Hong Deng;
Qin Xu;
Qiang Zhang;
Chunfeng Liu;
Lei Ren

Publication type:

Article

Research progress of galectins in glioma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02318-4

By:

Feng, Xin-Li;
Su, Gang;
Wu, Qiong-Hui;
Jia, Qi;
Zhang, Zhen-Chang

Publication type:

Article

Mechanism and application of lactylation in cancers.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01415-9

By:

Wang, Jiewen;
Peng, Mingjing;
Oyang, Linda;
Shen, Mengzhou;
Li, Shizhen;
Jiang, Xianjie;
Ren, Zongyao;
Peng, Qiu;
Xu, Xuemeng;
Tan, Shiming;
Xia, Longzheng;
Yang, Wenjuan;
Li, Haofan;
Wu, Nayiyuan;
Tang, Yanyan;
Lin, Jinguan;
Liao, Qianjin;
Han, Yaqian;
Zhou, Yujuan

Publication type:

Article

间质性肺疾病急性加重危险因素及治疗进展.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 5, p. 1219, doi. 10.3969/j.issn.1009-5519.2025.05.035

By:

罗子悦;
江宇

Publication type:

Article

IGF2BP3在肝癌中的研究进展.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 5, p. 1214, doi. 10.3969/j.issn.1009-5519.2025.05.034

By:

杨宛林;
叶宇璐;
宁登冲;
叶霞;
蓝金艳;
易廷庄

Publication type:

Article

Novel insights into the N 6-methyladenosine modification on circRNA in cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1554888

By:

Xu, Qingling;
Jia, Yi;
Liu, Ying;
Wu, Bing;
Wang, Jianxun;
Ao, Xiang;
Ding, Wei

Publication type:

Article

Comprehensive analysis of breast cancer oxidative stress related gene signature: a combination of bulk and single-cell RNA sequencing analysis.

Published in:

Mammalian Genome, 2025, v. 36, n. 2, p. 692, doi. 10.1007/s00335-025-10130-2

By:

Shao, Yuheng;
Zhang, Yumeng;
Chen, Jie;
Yang, Liang;
Wu, Meihong;
Fan, Zhiyuan;
Zhuang, Zhigang

Publication type:

Article

Inhibition of TPI1 Sensitizes Cisplatin-Resistant Oral Cancer to Ferroptosis.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1225, doi. 10.3390/biomedicines13051225

By:

Wang, Dandan;
Zheng, Huimin;
Chen, Yumin;
Hao, Jialin;
Zhou, Yuan;
Li, Nan

Publication type:

Article

Targeting Drug Resistance in Cancer: Dimethoxycurcumin as a Functional Antioxidant Targeting ABCC3.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 599, doi. 10.3390/antiox14050599

By:

Nelen, Jochem;
Naponelli, Valeria;
Villalgordo-Soto, José Manuel;
Falasca, Marco;
Pérez-Sánchez, Horacio

Publication type:

Article

The Role of PANoptosis‐Related Genes in Predicting Breast Cancer Survival and Immune Prospect.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/3423698

By:

Zhang, Yuxi;
Liu, Zheming;
Zhang, Yixuan;
Zhang, Xue;
Yao, Yi;
Zhang, Chi;
Chakraborty, Supriya

Publication type:

Article

The Novel Imiqualine EAPB02303 Is a Potent Drug for Treating Acute Myeloid Leukemia.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 741, doi. 10.3390/biom15050741

By:

Makhoul, Perla;
Hleihel, Rita;
Itani, Shaymaa;
Hamie, Maguy;
Pagniagua-Gayraud, Stephanie;
Patinote, Cindy;
Richaud, Myriam;
Merhi, Raghida Abou;
El-Sabban, Marwan;
Galas, Simon;
Deleuze-Masquefa, Carine;
Bonnet, Pierre-Antoine;
El Hajj, Hiba

Publication type:

Article

Exosome-Mediated Chemoresistance in Cancers: Mechanisms, Therapeutic Implications, and Future Directions.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 685, doi. 10.3390/biom15050685

By:

Liu, Gengqi;
Liu, Jingang;
Li, Silu;
Zhang, Yumiao;
He, Ren

Publication type:

Article

Emerging Multifunctional Biomaterials for Addressing Drug Resistance in Cancer.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 497, doi. 10.3390/biology14050497

By:

El-Tanani, Mohamed;
Rabbani, Syed Arman;
Babiker, Rasha;
El-Tanani, Yahia;
Satyam, Shakta Mani;
Porntaveetus, Thantrira

Publication type:

Article

The potential of targeting autophagy-related non-coding RNAs in the treatment of lung cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1551258

By:

Li, Juan;
Gan, Jimei;
Shi, Shenggan;
Huang, Juying;
Yang, Yong

Publication type:

Article

A lactate-related tSNE signature defines prognostic subtypes of bladder cancer and reveals LINC01094-mediated VIM stabilization in metastasis and drug resistance.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1593523

By:

Zhang, Pu;
Zhang, Hegan;
Yu, Wanli;
Fan, Dage;
Pan, Yao;
Zhuang, Wei;
Cai, Fangzhen;
He, Qingliu

Publication type:

Article

The Cordyceps Genus as a Potential Source of Bioactive Compounds for Adjuvant Cancer Therapy: A Network Pharmacology Approach.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 667, doi. 10.3390/ph18050667

By:

Gonzalez-Llerena, Jose Luis;
Treviño-Almaguer, Daniela;
Leal-Mendez, Jesus Alejandro;
Garcia-Valdez, Gael;
Balderas-Moreno, Arely Guadalupe;
Heya, Michel Stéphane;
Balderas-Renteria, Isaias;
Camacho-Corona, María del Rayo;
Espinosa-Rodriguez, Bryan Alejandro

Publication type:

Article

ADAM Proteases in Cancer: Biological Roles, Therapeutic Challenges, and Emerging Opportunities.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1703, doi. 10.3390/cancers17101703

By:

Arora, Sakshi;
Scott, Andrew M.;
Janes, Peter W.

Publication type:

Article

Interleukin-6 Is a Crucial Factor in Shaping the Inflammatory Tumor Microenvironment in Ovarian Cancer and Determining Its Hot or Cold Nature with Diagnostic and Prognostic Utilities.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1691, doi. 10.3390/cancers17101691

By:

Amer, Hina;
Flanagan, Katie L.;
Kampan, Nirmala C.;
Itsiopoulos, Catherine;
Scott, Clare L.;
Kartikasari, Apriliana E. R.;
Plebanski, Magdalena

Publication type:

Article

Exploratory Analysis of Molecular Subtypes in Early-Stage Osteosarcoma: Identifying Resistance and Optimizing Therapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1677, doi. 10.3390/cancers17101677

By:

Bojic, Luka;
Peric, Mina;
Karanovic, Jelena;
Milosevic, Emilija;
Kovacevic Grujicic, Natasa;
Milivojevic, Milena

Publication type:

Article

The CXCL1-CXCR2 Axis as a Component of Therapy Resistance, a Source of Side Effects in Cancer Treatment, and a Therapeutic Target.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1674, doi. 10.3390/cancers17101674

By:

Korbecki, Jan;
Bosiacki, Mateusz;
Pilarczyk, Maciej;
Kot, Marcin;
Defort, Piotr;
Walaszek, Ireneusz;
Chlubek, Dariusz;
Baranowska-Bosiacka, Irena

Publication type:

Article

Chondrosarcoma: Multi-Targeting Therapeutic Effects of Doxorubicin, BEZ235, and the Small Molecule Aspartyl-Asparaginyl-β-hydroxylase Inhibitor SMI1182.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1671, doi. 10.3390/cancers17101671

By:

Fife, Megan;
Tong, Ming;
Das, Bhaskar;
Rodriguez, Rene;
Chokkalingam, Parthiban;
Carlson, Rolf I.;
de la Monte, Suzanne M.

Publication type:

Article

Petosemtamab, a Bispecific Antibody Targeting Epidermal Growth Factor Receptor (EGFR) and Leucine-Rich G Repeat-Containing Protein-Coupled Receptor (LGR5) Designed for Broad Clinical Applications.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1665, doi. 10.3390/cancers17101665

By:

Lundberg, Ante S.;
Geuijen, Cecile A. W.;
Hill, Sally;
Lammerts van Bueren, Jeroen J.;
Fumagalli, Arianna;
de Kruif, John;
Silverman, Peter B.;
Tabernero, Josep

Publication type:

Article

CAF-Targeting Antibody–Drug Conjugates (ADCs) in Solid Cancers.

Published in:

2025

By:

Papavassiliou, Kostas A.;
Sofianidi, Amalia A.;
Papavassiliou, Athanasios G.

Publication type:

Editorial

Mechanisms and Therapeutic Strategies for Endocrine Resistance in Breast Cancer: A Comprehensive Review and Meta-Analysis.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1653, doi. 10.3390/cancers17101653

By:

Khan, Asiya;
Sisodiya, Sandeep;
Aftab, Mehreen;
Tanwar, Pranay;
Hussain, Showket;
Gupta, Vivek

Publication type:

Article

CRISPR/Cas9 Screening Highlights PFKFB3 Gene as a Major Contributor to 5-Fluorouracil Resistance in Esophageal Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1637, doi. 10.3390/cancers17101637

By:

Xue, Feng;
Yang, Hai;
Xu, Pengyan;
Zhang, Shuman;
Britzen-Laurent, Nathalie;
Bao, Li-Li;
Grützmann, Robert;
Krautz, Christian;
Pilarsky, Christian

Publication type:

Article

Clinical Characteristics and Survival of Ovarian Cancer Patients According to Homologous Recombination Deficiency Status.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1628, doi. 10.3390/cancers17101628

By:

Sisman, Yagmur;
Schejbel, Lone;
Schnack, Tine Henrichsen;
Høgdall, Claus;
Høgdall, Estrid

Publication type:

Article

Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1613, doi. 10.3390/cancers17101613

By:

Bianchi, Nicoletta;
Ancona, Pietro;
Aguiari, Gianluca

Publication type:

Article