Works matching DE "TUMOR microenvironment"

Results: 5000

Exploring the relationship between hypoxia in lung adenocarcinoma and tumor microenvironment immune cell infiltration.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02822-7

By:

Gu, Changcong;
Guo, Shuai;
Li, Haoxiang

Publication type:

Article

Research progress of galectins in glioma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02318-4

By:

Feng, Xin-Li;
Su, Gang;
Wu, Qiong-Hui;
Jia, Qi;
Zhang, Zhen-Chang

Publication type:

Article

Identification of novel susceptibility loci for testicular germ cell tumors through multi-omics analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02775-x

By:

Xu, Yuangao;
Shi, Hua;
Xiong, Jieyu;
Wu, Yikun;
Wu, Xiaoyu;
Xu, Yuanbo;
Wang, Yuanlin;
Xu, Shuxiong

Publication type:

Article

Engineered probiotic-mediated intratumoral delivery and controlled release of bacterial collagenase for cancer therapy.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 1, p. 226, doi. 10.1016/j.synbio.2024.09.001

By:

Hong-Rui Li;
Bang-Ce Ye

Publication type:

Article

Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2088, doi. 10.3390/molecules30102088

By:

Peng, Xia;
Yu, Siqi;
Xu, Lin;
Wang, Qinghua;
Yang, Lin;
Su, Yi;
Xiong, Zhirou;
Shao, Mengjie;
Geng, Meiyu;
Zhang, Ao;
Zhang, Lei;
Ai, Jing;
Ding, Chunyong

Publication type:

Article

Deciphering the cellular and molecular landscape of cervical cancer progression through single-cell and spatial transcriptomics.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00948-z

By:

Xia, Peng;
Zhou, Juanhong;
Shen, Rong;
Wang, Degui

Publication type:

Article

Bacteria and Carcinogenesis and the Management of Cancer: A Narrative Review.

Published in:

Pathogens, 2025, v. 14, n. 5, p. 509, doi. 10.3390/pathogens14050509

By:

Plewa, Paulina;
Kiełbowski, Kajetan;
Mentel, Oliwia;
Figiel, Karolina;
Bakinowska, Estera;
Becht, Rafał;
Banach, Bolesław;
Pawlik, Andrzej

Publication type:

Article

Increased STAT3 Phosphorylation in CD4 + T-Cells of Treated Patients with Chronic Lymphocytic Leukemia and Changes in Circulating Regulatory T-Cell Subsets Relative to Tumor Mass Distribution Value and Disease Duration.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1204, doi. 10.3390/biomedicines13051204

By:

Dreisinger, Mojca;
Roškar, Zlatko;
Goropevšek, Aleš;
Zakelšek, Andreja;
Čurič, Sara;
Živko, Nada;
Bevc, Sebastjan;
Homšak, Evgenija

Publication type:

Article

DBI as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1115, doi. 10.3390/biomedicines13051115

By:

Tian, Ting;
Han, Huan;
Huang, Jingtao;
Ma, Jun'e;
Ran, Ruoxi

Publication type:

Article

Lipid-Metabolism-Related Gene Signature Predicts Prognosis and Immune Microenvironment Alterations in Endometrial Cancer.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1050, doi. 10.3390/biomedicines13051050

By:

Wu, Zhangxin;
Nie, Yufei;
Kong, Deshui;
Xue, Lixiang;
He, Tianhui;
Zhang, Kuaile;
Zhang, Jie;
Shang, Chunliang;
Guo, Hongyan

Publication type:

Article

Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03924-6

By:

Kanoda, Ryo;
Nakajima, Shotaro;
Okayama, Hirokazu;
Kaneta, Akinao;
Chida, Shun;
Matsumoto, Takuro;
Saito, Katsuharu;
Kikuchi, Tomohiro;
Maruyama, Yuya;
Suzuki, Hiroya;
Mimura, Kosaku;
Saito, Motonobu;
Hanayama, Hiroyuki;
Sakamoto, Wataru;
Momma, Tomoyuki;
Saze, Zenichiro;
Kono, Koji

Publication type:

Article

CXCL12 links bladder cancer and diabetes as a potential biomarker.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-01357-9

By:

Ma, Mingyu;
Wang, Shufei;
Wang, Kongjia;
Jiang, Bo;
Li, Jingwen;
Hou, Sichuan

Publication type:

Article

Machine learning identifies SRD5A3 as a propionate-related prognostic biomarker in triple-negative breast cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-01274-x

By:

Pan, Kelun;
Qiu, Pengjun;
Liang, Huikai;
Wan, Ningning;
Liu, Zundong;
Guo, Qiaonan

Publication type:

Article

The Prognostic Impact of the Tumor Immune Microenvironment in Synovial Sarcoma: An Immunohistochemical Analysis Using Digital Pathology and Conventional Interpretation.

Published in:

Journal of Personalized Medicine, 2025, v. 15, n. 5, p. 169, doi. 10.3390/jpm15050169

By:

Medina-Ceballos, Emilio;
Giner, Francisco;
Machado, Isidro;
Heras-Morán, Begoña;
Espino, Mónica;
Navarro, Samuel;
Llombart-Bosch, Antonio

Publication type:

Article

Survivin Interference and SurVaxM as an Adjunct Therapy for Glioblastoma Multiforme.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 755, doi. 10.3390/cells14100755

By:

Elliott, Willie James;
Gurramkonda, Nandini;
Guda, Maheedhara R.;
Tsung, Andrew J.;
Velpula, Kiran K.

Publication type:

Article

Modeling Tumor Microenvironment Complexity In Vitro: Spheroids as Physiologically Relevant Tumor Models and Strategies for Their Analysis.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 732, doi. 10.3390/cells14100732

By:

Shah, Shrey;
D'Souza, Gerard G. M.

Publication type:

Article

Unconventional T Cells' Role in Cancer: Unlocking Their Hidden Potential to Guide Tumor Immunity and Therapy.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 720, doi. 10.3390/cells14100720

By:

Pinco, Paola;
Facciotti, Federica

Publication type:

Article

Exosome-Mediated Chemoresistance in Cancers: Mechanisms, Therapeutic Implications, and Future Directions.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 685, doi. 10.3390/biom15050685

By:

Liu, Gengqi;
Liu, Jingang;
Li, Silu;
Zhang, Yumiao;
He, Ren

Publication type:

Article

The Role of Cancer Organoids in Ferroptosis, Pyroptosis, and Necroptosis: Functions and Clinical Implications.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 659, doi. 10.3390/biom15050659

By:

Lu, Dingci;
Xia, Bingqian;
Feng, Tianquan;
Qi, Gui;
Ma, Zhaowu

Publication type:

Article

Bolstering CD8 + T Cells' Antitumor Immunity: A Promising Strategy to Improve the Response to Advanced Prostate Cancer Treatment.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 544, doi. 10.3390/biology14050544

By:

Dang, Beijing;
Liang, Lixin;
Li, Zhijun;
Luo, Junli;
Zhong, Shangwei

Publication type:

Article

Single-Cell Transcriptomic Profiling Reveals KRAS/TP53-Driven Neutrophil Reprogramming in Luad: A Multi-Gene Prognostic Model and Therapeutic Targeting of RHOV.

Published in:

Oncology Research, 2025, v. 33, n. 6, p. 1383, doi. 10.32604/or.2025.062584

By:

Ye, Yinghui;
Luo, Yulou;
Sun, Yutian;
Zhang, Yujie;
Lin, Jiaxin;
Yang, Ziling;
Xu, Anping;
Xue, Bei

Publication type:

Article

Molecular insights into immune evasion in head and neck squamous cell carcinomas: Toward a promising treatment strategy.

Published in:

Oncology Research, 2025, v. 33, n. 6, p. 1271, doi. 10.32604/or.2025.062207

By:

KIM, HYEON JI;
JOO, BO KYUNG;
BYUN, JIN-SEOK;
KIM, DO-YEON

Publication type:

Article

Single-cell and spatial transcriptome analyses reveal tumor heterogeneity and immune remodeling involved in pituitary neuroendocrine tumor progression.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60028-5

By:

Su, Wan;
Ye, Zhang;
Liu, Jifang;
Deng, Kan;
Liu, Jinghua;
Zhu, Huijuan;
Duan, Lian;
Shi, Chen;
Wang, Linjie;
Zhao, Yuxing;
Gong, Fengying;
Zhang, Yi;
Hou, Bo;
You, Hui;
Feng, Feng;
Ling, Qing;
Xiao, Yu;
Guo, Yongdong;
Fan, Wenyi;
Zhang, Sumei

Publication type:

Article

The impact of gliomas on the normal brain microenvironment: a pilot study.

Published in:

Journal of Histotechnology, 2025, v. 48, n. 2, p. 93, doi. 10.1080/01478885.2024.2408505

By:

Riha, Nicole;
Moore, Jacen S.;
Criswell, Sheila

Publication type:

Article

Pathways and outputs orchestrated in tumor microenvironment cells by hypoxia-induced tumor-derived exosomes in pan-cancer.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 539, doi. 10.1007/s13402-025-01042-z

By:

Capik, Ozel;
Karatas, Omer Faruk

Publication type:

Article

Development and characterisation of a novel 3D in vitro model of obesity-associated breast cancer as a tool for drug testing.

Published in:

NPJ Breast Cancer, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41523-025-00766-3

By:

Blyth, Rhianna R. R.;
Laversin, Stèphanie A.;
Foxall, Russell B.;
Savva, Constantinos;
Copson, Ellen;
Cutress, Ramsey I.;
Birts, Charles N.;
Beers, Stephen A.

Publication type:

Article

A novel Tc17 population recruited by tumor cells promotes tumor progression in gastric cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1592328

By:

Wang, Yichao;
Yuan, Hao;
Tan, Yayun;
Wu, Li;
Zhao, Xinchen;
Yang, Zeyuan;
Dai, Shaoxing;
Yang, Naixue

Publication type:

Article

Integrated single-cell and transcriptome sequencing data reveal the value of IL1RAP in gastric cancer microenvironment and prognosis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1584619

By:

Yang, Weifeng;
Wu, Xiaohua;
Wang, Jian;
Ou, Wenquan;
Huang, Xing

Publication type:

Article

Immune-metabolic crosstalk in HNSCC: mechanisms and therapeutic opportunities.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1553284

By:

Qin, Xiyuan;
Wu, Hui;
Pan, Jiaqi;
Kang, Kai;
Shi, Yujie;
Bu, Shoushan

Publication type:

Article

The impact of the tumor microenvironment on macrophages.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572764

By:

Xiao, Man;
Li, Xiaoduan

Publication type:

Article

Case Report: FAP<sup>+</sup> fibroblasts and SPP1<sup>+</sup> macrophages in SMARCA2-deficient while SMARCA4-preserved poorly differentiated lung adenocarcinoma: two case reports and multi-omics analysis.

Published in:

2025

By:

Wang, Zhaoxuan;
Wang, Junying;
Wang, Shengmin;
Xu, Weijiao;
Zhang, Yixiang

Publication type:

Case Study

Interplay between cancer-associated fibroblasts and dendritic cells: implications for tumor immunity.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1515390

By:

Mentucci, Fátima María;
Ferrara, María Gracia;
Ercole, Agustina;
Rumie Vittar, Natalia Belén;
Lamberti, María Julia

Publication type:

Article

Unraveling the immunosuppressive microenvironment of glioblastoma and advancements in treatment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1590781

By:

Jiang, Dongxin;
Li, Yunqian

Publication type:

Article

Immunosuppressive tumor microenvironment in pancreatic cancer: mechanisms and therapeutic targets.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582305

By:

Pan, Da;
Li, Xinyue;
Qiao, Xiao;
Wang, Qiqi

Publication type:

Article

Spatial proteomics of the tumor microenvironment in melanoma: current insights and future directions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1568456

By:

Bungaro, Chiara;
Guida, Michele;
Apollonio, Benedetta

Publication type:

Article

Unraveling the immune evasion mechanisms in the tumor microenvironment of head and neck squamous cell carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1597202

By:

Zhao, Xuri;
Zhu, Yaping;
He, Youya;
Gu, Weiyan;
Zhou, Qi;
Jin, Bei;
Chen, Shenguo;
Lin, Haisheng

Publication type:

Article

Molecular subtypes based on ferroptosis-related genes and tumor microenvironment infiltration characterization in small cell lung cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1574434

By:

Wang, Xin;
Xu, Zhenyi;
Lin, Zhen;
Wu, Dawei;
Tang, Yu;
Pei, Zhihua;
Gao, Yibo;
He, Jie

Publication type:

Article

Intercellular communication between FAP+ fibroblasts and SPP1+ macrophages in prostate cancer via multi-omics.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1560998

By:

Wu, Tingting;
Li, Xinyu;
Zheng, Fei;
Liu, Hanchao;
Yu, Yang

Publication type:

Article

Tumor-infiltrating immune cells state-implications for various breast cancer subtypes.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1550003

By:

Xu, Tianshuang;
Zhang, Hongjun;
Yang, Burton B.;
Qadir, Javeria;
Yuan, Hui;
Ye, Ting

Publication type:

Article

Neutrophil-Camouflaged Stealth Liposomes for Photothermal-Induced Tumor Immunotherapy Through Intratumoral Bacterial Activation.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 614, doi. 10.3390/pharmaceutics17050614

By:

Chen, Xinxin;
Sun, Jiang;
Ye, Tingxian;
Li, Fanzhu

Publication type:

Article

Nano-Drug Delivery Systems for Bone Metastases: Targeting the Tumor–Bone Microenvironment.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 603, doi. 10.3390/pharmaceutics17050603

By:

Bakir, Mohamad;
Dawalibi, Ahmad;
Mufti, Mohammad Alaa;
Behiery, Ayman;
Mohammad, Khalid S.

Publication type:

Article

Harnessing the Power of Nanocarriers to Exploit the Tumor Microenvironment for Enhanced Cancer Therapy.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 746, doi. 10.3390/ph18050746

By:

Aldhubiab, Bandar;
Almuqbil, Rashed M.;
Nair, Anroop B.

Publication type:

Article

Sindbis Virus Platform Provides an Oncolytic-Virus-Mediated and Immunotherapeutic Strategy to Overcome the Challenging Microenvironment of Pancreatic Cancer.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 725, doi. 10.3390/ph18050725

By:

Opp, Silvana;
Pampeno, Christine;
Hurtado, Alicia;
Meruelo, Daniel

Publication type:

Article

Competitive Endogenous RNA Network Involving Immune Subgroups, Infiltration, and lncRNAs in Prostate Cancer.

Published in:

Genes, 2025, v. 16, n. 5, p. 527, doi. 10.3390/genes16050527

By:

Niu, Wenkang;
Zhang, Tingting;
Ma, Lei

Publication type:

Article

Gut Bacteria-Based Cancer Therapy and Anti-Solid Tumor Mechanisms.

Published in:

Microbiology Research, 2025, v. 16, n. 5, p. 92, doi. 10.3390/microbiolres16050092

By:

Zhang, Tianzhu;
Yu, Xiao-Mei;
Yang, Shang-Tian;
Zhou, Wen-Wen

Publication type:

Article

NK cell-derived artificial extracellular vesicles elicit potent anti-tumor efficacy and tumor microenvironment reprogramming capability.

Published in:

Cancer Nanotechnology (1868-6958), 2025, v. 16, n. 1, p. 1, doi. 10.1186/s12645-025-00328-z

By:

Zhou, Xinyue;
Yuan, Hang;
Zhu, Xinyue;
Liu, Yangli;
Xiao, Jinmin;
Xie, Xueting;
Che, Linlin;
Fang, Cheng;
Yao, Chao;
Hu, Dan;
Zhou, Yufu;
Wang, Lixin;
Gong, Chenyuan;
Zhu, Shiguo

Publication type:

Article

The Spatial Proximity of CD8 + FoxP3 + PD-1 + Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer.

Published in:

Current Oncology, 2025, v. 32, n. 5, p. 262, doi. 10.3390/curroncol32050262

By:

Hu, Zijuan;
Hu, Zhihuang;
Chen, Keji;
Huang, Huixia;
Zhong, Xinyang;
Wang, Yaxian;
Chen, Jiayu;
He, Xuefeng;
Shi, Di;
Zeng, Yupeng;
Li, Jiwei;
Zhou, Xiaoyan;
Wei, Ping

Publication type:

Article

Human Herpes Virus Genotype and Immunological Gene Expression Profile in Prostate Cancer with Prominent Inflammation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4945, doi. 10.3390/ijms26104945

By:

Todorova, Elena;
Kavrakova, Anita;
Derimachkovski, Goran;
Georgieva, Bilyana;
Odzhakov, Feodor;
Bachurska, Svitlana;
Terziev, Ivan;
Boyadzhieva, Maria-Elena;
Valkov, Trifon;
Popov, Elenko;
Slavov, Chavdar;
Tourtourikov, Ivan;
Mitev, Vanyo;
Todorova, Albena

Publication type:

Article

CD71-Mediated Effects of Soluble Vasorin on Tumor Progression, Angiogenesis and Immunosuppression.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4913, doi. 10.3390/ijms26104913

By:

Zhao, Yuechao;
Xiao, Can;
Li, Shaohua;
Huang, Aixue;
Li, Hui;
Dong, Jie;
Qu, Qiaoping;
Liu, Xuemei;
Gao, Bo;
Shao, Ningsheng

Publication type:

Article

Inhibition of MCP1 (CCL2) Enhances Antitumor Activity of NK Cells Against HCC Cells Under Hypoxia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4900, doi. 10.3390/ijms26104900

By:

Lee, Hwan Hee;
Kim, Juhui;
Park, Eunbi;
Kang, Hyojeung;
Cho, Hyosun

Publication type:

Article