Works matching DE "SYNAPTOTAGMINS"

Results: 133

Synaptotagmin-1 binds to PIP2-containing membrane but not to SNAREs at physiological ionic strength.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 10, p. 815, doi. 10.1038/nsmb.3097

By:

Park, Yongsoo;
Seo, Jong Bae;
Fraind, Alicia;
Pérez-Lara, Angel;
Yavuz, Halenur;
Han, Kyungreem;
Jung, Seung-Ryoung;
Kattan, Iman;
Walla, Peter Jomo;
Choi, MooYoung;
Cafiso, David S;
Koh, Duk-Su;
Jahn, Reinhard

Publication type:

Article

Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 7, p. 555, doi. 10.1038/nsmb.3035

By:

Brewer, Kyle D;
Bacaj, Taulant;
Cavalli, Andrea;
Camilloni, Carlo;
Swarbrick, James D;
Liu, Jin;
Zhou, Amy;
Zhou, Peng;
Barlow, Nicholas;
Xu, Junjie;
Seven, Alpay B;
Prinslow, Eric A;
Voleti, Rashmi;
Häussinger, Daniel;
Bonvin, Alexandre M J J;
Tomchick, Diana R;
Vendruscolo, Michele;
Graham, Bim;
Südhof, Thomas C;
Rizo, Josep

Publication type:

Article

Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 679, doi. 10.1038/nsmb.2570

By:

Honigmann, Alf;
van den Bogaart, Geert;
Iraheta, Emilio;
Risselada, H Jelger;
Milovanovic, Dragomir;
Mueller, Veronika;
Müllar, Stefan;
Diederichsen, Ulf;
Fasshauer, Dirk;
Grubmüller, Helmut;
Hell, Stefan W;
Eggeling, Christian;
Kühnel, Karin;
Jahn, Reinhard

Publication type:

Article

Controlling synaptotagmin activity by electrostatic screening.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 10, p. 991, doi. 10.1038/nsmb.2375

By:

Park, Yongsoo;
Hernandez, Javier M;
van den Bogaart, Geert;
Ahmed, Saheeb;
Holt, Matthew;
Riedel, Dietmar;
Jahn, Reinhard

Publication type:

Article

The Extended Synaptotagmins of Physcomitrium patens.

Published in:

Plants (2223-7747), 2025, v. 14, n. 7, p. 1027, doi. 10.3390/plants14071027

By:

Kaier, Alexander;
Ntefidou, Maria

Publication type:

Article

Arabidopsis SYT1 maintains stability of cortical endoplasmic reticulum networks and VAP27-1-enriched endoplasmic reticulum-plasma membrane contact sites.

Published in:

Journal of Experimental Botany, 2016, v. 67, n. 21, p. 6161, doi. 10.1093/jxb/erw381

By:

Wei Siao;
Pengwei Wang;
Voigt, Boris;
Hussey, Patrick J.;
Baluska, Frantisek

Publication type:

Article

Synaptotagmin-7 is overexpressed in hepatocellular carcinoma and regulates hepatocellular carcinoma cell proliferation via Chk1-p53 signaling.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 4283, doi. 10.2147/OTT.S143619

By:

Hao Jin;
Geliang Xu;
Qiang Zhang;
Qing Pang;
Meifang Fang

Publication type:

Article

Synaptotagmin I delays the fast inactivation of Kv1.4 channel through interaction with its N-terminus.

Published in:

Molecular Brain, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-6606-7-4

By:

Chunliang Xie;
Haibo Su;
Tianyao Guo;
Yizhong Yan;
Xiaozhen Peng;
Rui Cao;
Ying Wang;
Ping Chen;
Xianchun Wang;
Songping Liang

Publication type:

Article

The Cytoplasmic Domain of Rat Synaptotagmin I Enhances Synaptic Transmission.

Published in:

Cellular & Molecular Neurobiology, 2014, v. 34, n. 5, p. 659, doi. 10.1007/s10571-014-0040-2

By:

Hua, Shao-Ying;
Syed, Ali;
Aupérin, Thierry;
Tong, Liang

Publication type:

Article

Neurotransmitter Vesicle Release from Human Model Neurons (NT2) is Sensitive to Botulinum Toxin A.

Published in:

Cellular & Molecular Neurobiology, 2012, v. 32, n. 6, p. 1021, doi. 10.1007/s10571-012-9818-2

By:

Tegenge, Million;
Böhnel, Helge;
Gessler, Frank;
Bicker, Gerd

Publication type:

Article

A molecular machine for neurotransmitter release: synaptotagmin and beyond.

Published in:

Nature Medicine, 2013, v. 19, n. 10, p. 1227, doi. 10.1038/nm.3338

By:

Südhof, Thomas C

Publication type:

Article

Synaptotagmin II and Gangliosides Bind Independently with Botulinum Neurotoxin B but Each Restrains the Other.

Published in:

Protein Journal, 2014, v. 33, n. 3, p. 278, doi. 10.1007/s10930-014-9557-y

By:

Atassi, M.;
Taruishi, Midori;
Naqvi, Masooma;
Steward, Lance;
Aoki, K.

Publication type:

Article

v-SNARE function in chromaffin cells.

Published in:

Pflügers Archiv: European Journal of Physiology, 2018, v. 470, n. 1, p. 169, doi. 10.1007/s00424-017-2066-z

By:

Dhara, Madhurima;
Mohrmann, Ralf;
Bruns, Dieter

Publication type:

Article

Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.

Published in:

Nature, 2015, v. 525, n. 7567, p. 62, doi. 10.1038/nature14975

By:

Zhou, Qiangjun;
Lai, Ying;
Bacaj, Taulant;
Zhao, Minglei;
Lyubimov, Artem Y.;
Uervirojnangkoorn, Monarin;
Zeldin, Oliver B.;
Brewster, Aaron S.;
Sauter, Nicholas K.;
Cohen, Aina E.;
Soltis, S. Michael;
Alonso-Mori, Roberto;
Chollet, Matthieu;
Lemke, Henrik T.;
Pfuetzner, Richard A.;
Choi, Ucheor B.;
Weis, William I.;
Diao, Jiajie;
Südhof, Thomas C.;
Brunger, Axel T.

Publication type:

Article

Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics.

Published in:

Journal of Cell Biology, 2014, v. 204, n. 7, p. 1123, doi. 10.1083/jcb.201311085

By:

Dhara, Madhurima;
Yarzagaray, Antonio;
Schwarz, Yvonne;
Dutta, Soumyajit;
Grabner, Chad;
Moghadam, Paanteha K.;
Bost, Anneka;
Schirra, Claudia;
Rettig, Jens;
Reim, Kerstin;
Brose, Nils;
Mohrmann, Ralf;
Bruns, Dieter

Publication type:

Article

Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion.

Published in:

Journal of Cell Biology, 2011, v. 195, n. 7, p. 1159, doi. 10.1083/jcb.201104079

By:

Zhao Wang;
Huisheng Liu;
Yiwen Gu;
Chapman, Edwin R.

Publication type:

Article

Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.64527

By:

Tawfik, Bassam;
Martins, Joana S.;
Houy, Sébastien;
Imig, Cordelia;
Pinheiro, Paulo S.;
Wojcik, Sonja M.;
Brose, Nils;
Cooper, Benjamin H.;
Sørensen, Jakob Balslev

Publication type:

Article

Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics.

Published in:

Toxins, 2018, v. 10, n. 10, p. 421, doi. 10.3390/toxins10100421

By:

Davies, Jonathan R.;
Acharya, K. Ravi;
Liu, Sai Man

Publication type:

Article

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin.

Published in:

Toxins, 2016, v. 8, n. 5, p. 154, doi. 10.3390/toxins8050154

By:

Weisemann, Jasmin;
Stern, Daniel;
Mahrhold, Stefan;
Dorner, Brigitte G.;
Rummel, Andreas

Publication type:

Article

Enhanced synaptotagmin plasticity derived from pairing intrinsic disorder with synaptic vesicle lipids.

Published in:

Communicative & Integrative Biology, 2017, v. 10, n. 4, p. 1, doi. 10.1080/19420889.2017.1343772

By:

Fealey, Michael E.;
Thomas, David D.;
Hinderliter, Anne

Publication type:

Article

Allostery and instability in the functional plasticity of synaptotagmin I.

Published in:

Communicative & Integrative Biology, 2013, v. 6, n. 2, p. e22830-1, doi. 10.4161/cib.22830

By:

Fealey, Michael E.;
Hinderliter, Anne

Publication type:

Article

Apical Localization of Inositol 1,4,5-Trisphosphate Receptors Is Independent of Extended Synaptotagmins in Hepatocytes.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114043

By:

Amaya, Maria Jimena;
Oliveira, André G.;
Schroeder, Lena K.;
Allgeyer, Edward S.;
Bewersdorf, Joerg;
Nathanson, Michael H.

Publication type:

Article

Synaptotagmin-7 Is an Asynchronous Calcium Sensor for Synaptic Transmission in Neurons Expressing SNAP-23.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0114033

By:

Weber, Jens P.;
Toft-Bertelsen, Trine L.;
Mohrmann, Ralf;
Delgado-Martinez, Ignacio;
Sørensen, Jakob B.

Publication type:

Article

Differential Roles for Snapin and Synaptotagmin in the Synaptic Vesicle Cycle.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057842

By:

Yu, Szi-Chieh;
Klosterman, Susan M.;
Martin, Ashley A.;
Gracheva, Elena O.;
Richmond, Janet E.

Publication type:

Article

Negative Coupling as a Mechanism for Signal Propagation between C2 Domains of Synaptotagmin I.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046748

By:

Fealey, Michael E.;
Gauer, Jacob W.;
Kempka, Sarah C.;
Miller, Katie;
Nayak, Kamakshi;
Sutton, R. Bryan;
Hinderliter, Anne

Publication type:

Article

Ca2+ Regulates the Drosophila Stoned-A and Stoned-B Proteins Interaction with the C2B Domain of Synaptotagmin-1.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038822

By:

Soekmadj, Carolina;
Angkawidjaja, Clement;
Kelly, Leonard E.

Publication type:

Article

Differential Patterns of Synaptotagmin7 mRNA Expression in Rats with Kainate- and Pilocarpine-Induced Seizures.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036114

By:

Glavan, Gordana;
See, Ronald Eugene;
Zivin, Marko

Publication type:

Article

Golgi Apparatus-Localized Synaptotagmin 2 Is Required for Unconventional Secretion in Arabidopsis.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0026477

By:

Haiyan Zhang;
Liang Zhang;
Bin Gao;
Hai Fan;
Jingbo Jin;
Botella, Miguel A.;
Liwen Jiang;
Jinxing Lin

Publication type:

Article

Depression-like Behavior Induced by Nesfatin-1 in Rats: Involvement of Increased Immune Activation and Imbalance of Synaptic Vesicle Proteins.

Published in:

Frontiers in Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnins.2015.00429

By:

Jin-Fang Ge;
Ya-Yun Xu;
Gan Qin;
Fei-Hu Chen;
Yao-Nan Peng;
Chao-Feng Zhang;
Xing-Rui Liu;
Li-Chuan Liang;
Zhong-Zheng Wang

Publication type:

Article

Chronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice.

Published in:

Age (0161-9152), 2015, v. 37, n. 5, p. 1, doi. 10.1007/s11357-015-9839-0

By:

Chen, Gui-Hai;
Tong, Jing-Jing;
Wang, Fang;
Hu, Xue-Qin;
Li, Xue-Wei;
Tao, Fei;
Wei, Zhao-Jun

Publication type:

Article

Up-regulation of Synaptotagmin IV within amyloid plaqueassociated dystrophic neurons in Tg2576 mouse model of Alzheimer's disease.

Published in:

Croatian Medical Journal, 2013, v. 54, n. 5, p. 419, doi. 10.3325/cmj.2013.54.419

By:

Tratnjek, Larisa;
Živin, Marko;
Glavan, Gordana

Publication type:

Article

Multiscale Structural Analysis of Plant ER-PM Contact Sites.

Published in:

Plant & Cell Physiology, 2017, v. 58, n. 3, p. 478, doi. 10.1093/pcp/pcw224

By:

McFarlane, Heather E.;
Eun Kyoung Lee;
van Bezouwen, Laura S.;
Ross, Bradford;
Rosado, Abel;
Samuels, A. Lacey

Publication type:

Article

Synaptotagmin 1 Negatively Controls the Two Distinct Immune Secretory Pathways to Powdery Mildew Fungi in Arabidopsis.

Published in:

Plant & Cell Physiology, 2016, v. 57, n. 6, p. 1133, doi. 10.1093/pcp/pcw061

By:

Hyeran Kim;
Hyeokjin Kwon;
Soohong Kim;
Mi Kyung Kim;
Botella, Miguel A.;
Hye Sup Yun;
Chian Kwon

Publication type:

Article

The effects of GABA transporter inhibition on synaptophysin and synaptotagmin expression in diazepam tolerance.

Published in:

World Journal of Biological Psychiatry, 2010, v. 11, n. 2_2, p. 439, doi. 10.3109/15622970902874932

By:

Schmitt, Ulrich;
Conner, Alex C.;
Rapp, Simone;
Kissling, Christian;
Jennen-Steinmetz, Christine;
Hünnerkopf, Regina;
Coogan, Andrew N.;
Thome, Johannes

Publication type:

Article

Calcium Regulation in the Protozoan Model, Paramecium tetraurelia.

Published in:

Journal of Eukaryotic Microbiology, 2014, v. 61, n. 1, p. 95, doi. 10.1111/jeu.12070

By:

Plattner, Helmut

Publication type:

Article

SYT1-associated neurodevelopmental disorder: a case series.

Published in:

2018

By:

Baker, Kate;
Gordon, Sarah L;
Melland, Holly;
Bumbak, Fabian;
Scott, Daniel J;
Jiang, Tess J;
Owen, David;
Turner, Bradley J;
Boyd, Stewart G;
Rossi, Mari;
Al-Raqad, Mohammed;
Elpeleg, Orly;
Peck, Dawn;
Mancini, Grazia M S;
Wilke, Martina;
Zollino, Marcella;
Marangi, Giuseppe;
Weigand, Heike;
Borggraefe, Ingo;
Haack, Tobias

Publication type:

journal article

Interactions Between SNAP-25 and Synaptotagmin-1 Are Involved in Vesicle Priming, Clamping Spontaneous and Stimulating Evoked Neurotransmission.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 47, p. 11865, doi. 10.1523/JNEUROSCI.1011-16.2016

By:

Schupp, Melanie;
Malsam, Jörg;
Ruiter, Marvin;
Scheutzow, Andrea;
Wierda, Keimpe D. B.;
Söllner, Thomas H.;
Sørensen, Jakob B.

Publication type:

Article

Upregulating Synaptotagmin 10 Protects Neurons.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 9, p. i

By:

Esch, Teresa

Publication type:

Article

A Post-Docking Role of Synaptotagmin 1-C2B Domain Bottom Residues R398/399 in Mouse Chromaffin Cells.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 42, p. 14172, doi. 10.1523/JNEUROSCI.1911-15.2015

By:

Kedar, Girish H.;
Munch, Anders S.;
van Weering, Jan R. T.;
Malsam, Jõrg;
Scheutzow, Andrea;
de Wit, Heidi;
Houy, Sébastien;
Tawfik, Bassam;
Söllner, Thomas H.;
Sørensen, Jakob B.;
Verhage, Matthijs

Publication type:

Article

An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 34, p. 11769, doi. 10.1523/JNEUROSCI.1694-15.2015

By:

Evans, Chantell S.;
Ruhl, David A.;
Chapman, Edwin R.

Publication type:

Article

Synaptotagmin-7 Is Essential for Ca2+-Triggered Delayed Asynchronous Release But Not for Ca2+-Dependent Vesicle Priming in Retinal Ribbon Synapses.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 31, p. 11024, doi. 10.1523/JNEUROSCI.0759-15.2015

By:

Fujun Luo;
Bacaj, Taulant;
Südhof, Thomas C.

Publication type:

Article

Spontaneous Vesicle Release Is Not Tightly Coupled to Voltage-Gated Calcium Channel-Mediated Ca2+ Influx and Is Triggered by a Ca2+ Sensor Other Than Synaptotagmin-2 at the Juvenile Mice Calyx of Held Synapses.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 26, p. 9632, doi. 10.1523/JNEUROSCI.0457-15.2015

By:

inye Dai;
Peihua Chen;
Hao Tian;
Jianyuan Sun

Publication type:

Article

Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 6, p. 2492, doi. 10.1523/JNEUROSCI.4248-14.2015

By:

Ning Zhang;
Gordon, Sarah L.;
Fritsch, Maximilian J.;
Esoof, Noor;
Campbell, David G.;
Gourlay, Robert;
Velupillai, Srikannathasan;
Macartney, Thomas;
Peggie, Mark;
van Aalten, Daan M. F.;
Cousin, Michael A.;
Alessi, Dario R.

Publication type:

Article

Peptidergic Cell-Specific Synaptotagmins in Drosophila: Localization to Dense-Core Granules and Regulation by the bHLH Protein DIMMED.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 39, p. 13195, doi. 10.1523/JNEUROSCI.2075-14.2014

By:

Park, Dongkook;
Li, Peiyao;
Dani, Adish;
Taghert, Paul H.

Publication type:

Article

An Alien Divalent Ion Reveals a Major Role for Ca2+ Buffering in Controlling Slow Transmitter Release.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 38, p. 12622, doi. 10.1523/JNEUROSCI.1990-14.2014

By:

Babai, Norbert;
Kochubey, Olexiy;
Keller, Daniel;
Schneggenburger, Ralf

Publication type:

Article

Innervation by a GABAergic Neuron Depresses Spontaneous Release in Glutamatergic Neurons and Unveils the Clamping Phenotype of Synaptotagmin-1.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 6, p. 2100, doi. 10.1523/JNEUROSCI.3934-13.2014

By:

Wierda, Keimpe D. B.;
Sørensen, Jakob B.

Publication type:

Article

Doc2b Synchronizes Secretion from Chromaffin Cells by Stimulating Fast and Inhibiting Sustained Release.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 42, p. 16459, doi. 10.1523/JNEUROSCI.2656-13.2013

By:

Pinheiro, Paulo S.;
de Wit, Heidi;
Walter, Alexander M.;
Groffen, Alexander J.;
Verhage, Matthijs;
Sørensen, Jakob B.

Publication type:

Article

Synaptotagmin Interaction with SNAP-25 Governs Vesicle Docking, Priming, and Fusion Triggering.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 36, p. 14417, doi. 10.1523/JNEUROSCI.1236-13.2013

By:

Mohrmann, Ralf;
De Wit, Heidi;
Connell, Emma;
Pinheiro, Paulo S.;
Leese, Charlotte;
Bruns, Dieter;
Davletov, Bazbek;
Verhage, Matthijs;
Sørensen, Jakob B.

Publication type:

Article

Synaptotagmin-12 Phosphorylation by cAMP-Dependent Protein Kinase Is Essential for Hippocampal Mossy Fiber LTP.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 23, p. 9769, doi. 10.1523/JNEUROSCI.5814-12.2013

By:

Kaeser-Woo, Yea Jin;
Younts, Thomas J.;
Xiaofei Yang;
Peng Zhou;
Dick Wu;
Castillo, Pablo E.;
Südhof, Thomas C.

Publication type:

Article

Dance of the SNAREs: Assembly and Rearrangements Detected with FRET at Neuronal Synapses.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 13, p. 5507, doi. 10.1523/JNEUROSCI.2337-12.2013

By:

Degtyar, Vadim;
Hafez, Ismail M.;
Bray, Christopher;
Zucker, Robert S.

Publication type:

Article