Works matching DE "THERAPEUTIC use of oligonucleotides"
Results: 112
Abstracts.
- Published in:
- 2018
- Publication type:
- Abstract
Abnormal thymic maturation and lymphoproliferation in MRL-Fas<sup>lpr/lpr</sup> mice can be partially reversed by synthetic oligonucleotides: implications for systemic lupus erythematosus and autoimmune lymphoproliferative syndrome.
- Published in:
- Lupus, 2017, v. 26, n. 7, p. 734, doi. 10.1177/0961203316676381
- By:
- Publication type:
- Article
Antisense oligonucleotide therapies: are they the "magic bullets"?
- Published in:
- 1994
- By:
- Publication type:
- Editorial
Development of antisense oligonucleotide (ASO) technology against Tgf-β signaling to prevent scarring during flexor tendon repair.
- Published in:
- Journal of Orthopaedic Research, 2015, v. 33, n. 6, p. 859, doi. 10.1002/jor.22890
- By:
- Publication type:
- Article
Oligonucleotide therapeutic approaches for Huntington disease.
- Published in:
- Journal of Clinical Investigation, 2011, v. 121, n. 2, p. 500, doi. 10.1172/JCI45130
- By:
- Publication type:
- Article
A Mathematical Analysis of the Selective Enrichment of NECEEM-Based Non-SELEX.
- Published in:
- Applied Biochemistry & Biotechnology, 2014, v. 173, n. 8, p. 2019, doi. 10.1007/s12010-014-0989-9
- By:
- Publication type:
- Article
Myeloid cells as a target for oligonucleotide therapeutics: turning obstacles into opportunities.
- Published in:
- Cancer Immunology, Immunotherapy, 2017, v. 66, n. 8, p. 979, doi. 10.1007/s00262-017-1966-2
- By:
- Publication type:
- Article
Antisense oligonucleotide delivery to cancer cell lines for the treatment of different cancer types.
- Published in:
- Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 8, p. 1938, doi. 10.3109/21691401.2015.1115409
- By:
- Publication type:
- Article
Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100), an antisense oligonucleotide targeting influenza a M1/M2 translation.
- Published in:
- British Journal of Clinical Pharmacology, 2018, v. 84, n. 1, p. 25, doi. 10.1111/bcp.13405
- By:
- Publication type:
- Article
Issue Highlights.
- Published in:
- 2016
- Publication type:
- Other
Injection site reactions after subcutaneous oligonucleotide therapy.
- Published in:
- British Journal of Clinical Pharmacology, 2016, v. 82, n. 2, p. 340, doi. 10.1111/bcp.12961
- By:
- Publication type:
- Article
Efficacy and Safety of Edifoligide, an E2F Transcription Factor Decoy, for Prevention of Vein Graft Failure Following Coronary Artery Bypass Graft Surgery: PREVENT IV: A Randomized Controlled Trial.
- Published in:
- JAMA: Journal of the American Medical Association, 2005, v. 294, n. 19, p. 2446
- By:
- Publication type:
- Article
First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer.
- Published in:
- British Journal of Cancer, 2013, v. 109, n. 10, p. 2579, doi. 10.1038/bjc.2013.619
- By:
- Publication type:
- Article
Intrathecal administration of nusinersen in adolescent and adult SMA type 2 and 3 patients.
- Published in:
- Journal of Neurology, 2019, v. 266, n. 1, p. 183, doi. 10.1007/s00415-018-9124-0
- By:
- Publication type:
- Article
Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics.
- Published in:
- Biomedicines, 2018, v. 6, n. 2, p. 51, doi. 10.3390/biomedicines6020051
- By:
- Publication type:
- Article
Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects.
- Published in:
- Biomedicines, 2017, v. 5, n. 3, p. 45, doi. 10.3390/biomedicines5030045
- By:
- Publication type:
- Article
Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells.
- Published in:
- Experimental & Therapeutic Medicine, 2014, v. 8, n. 4, p. 1247, doi. 10.3892/etm.2014.1897
- By:
- Publication type:
- Article
A phase 1 open-label trial shows that smad7 antisense oligonucleotide (GED0301) does not increase the risk of small bowel strictures in Crohn's disease.
- Published in:
- Alimentary Pharmacology & Therapeutics, 2012, v. 36, n. 9, p. 850, doi. 10.1111/apt.12051
- By:
- Publication type:
- Article
Identification of methylation-silenced genes in colorectal cancer cell lines: Genomic screening using oligonucleotide arrays.
- Published in:
- Scandinavian Journal of Gastroenterology, 2007, v. 42, n. 12, p. 1486, doi. 10.1080/00365520701491173
- By:
- Publication type:
- Article
Pharmacokinetics of High-Dose Abetimus Sodium in Normal Subjects With Specific Assessment of Effect on Coagulation.
- Published in:
- Journal of Clinical Pharmacology, 2008, v. 48, n. 8, p. 909, doi. 10.1177/0091270008319465
- By:
- Publication type:
- Article
Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Intrathecal administration of AYX2 DNA decoy produces a long-term pain treatment in rat models of chronic pain by inhibiting the KLF6, KLF9, and KLF15 transcription factors.
- Published in:
- Molecular Pain, 2017, v. 13, p. 1, doi. 10.1177/1744806917727917
- By:
- Publication type:
- Article
Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 2, p. 343, doi. 10.1007/s00280-013-2362-z
- By:
- Publication type:
- Article
Targeting MicroRNAs for Personalized Cancer Therapy.
- Published in:
- Medical Principles & Practice, 2013, v. 22, n. 5, p. 415, doi. 10.1159/000353562
- By:
- Publication type:
- Article
Long-Term Efficacy, Safety, and Pharmacokinetics of Drisapersen in Duchenne Muscular Dystrophy: Results from an Open-Label Extension Study.
- Published in:
- PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0161955
- By:
- Publication type:
- Article
Transferrin Receptor Targeted Lipopolyplexes for Delivery of Antisense Oligonucleotide G3139 in a Murine K562 Xenograft Model.
- Published in:
- Pharmaceutical Research, 2009, v. 26, n. 6, p. 1516, doi. 10.1007/s11095-009-9864-8
- By:
- Publication type:
- Article
Extended gene analysis can increase specificity of neonatal screening for cystic fibrosis.
- Published in:
- Acta Paediatrica, 2006, v. 95, n. 11, p. 1424, doi. 10.1080/08035250600781846
- By:
- Publication type:
- Article
RNA in the spotlight: the dawn of RNA therapeutics in the treatment of human disease.
- Published in:
- Cardiovascular Research, 2017, v. 113, n. 12, p. e43, doi. 10.1093/cvr/cvx170
- By:
- Publication type:
- Article
Antisense Oligonucleotide Therapies: The Promise and the Challenges from a Toxicologic Pathologist’s Perspective.
- Published in:
- Toxicologic Pathology, 2015, v. 43, n. 1, p. 78, doi. 10.1177/0192623314551840
- By:
- Publication type:
- Article
Species-specific Inflammatory Responses as a Primary Component for the Development of Glomerular Lesions in Mice and Monkeys Following Chronic Administration of a Second-generation Antisense Oligonucleotide.
- Published in:
- Toxicologic Pathology, 2014, v. 42, n. 5, p. 923, doi. 10.1177/0192623313505781
- By:
- Publication type:
- Article
Intravitreal treatment with antisense oligonucleotides targeting tumor necrosis factor-α in murine herpes simplex virus type 1 retinitis.
- Published in:
- Graefe's Archive of Clinical & Experimental Ophthalmology, 2012, v. 250, n. 2, p. 231, doi. 10.1007/s00417-011-1840-4
- By:
- Publication type:
- Article
Advances in the delivery of RNA therapeutics: from concept to clinical reality.
- Published in:
- Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0450-0
- By:
- Publication type:
- Article
HotSpots.
- Published in:
- Clinical Genetics, 2001, v. 60, n. 2, p. 102, doi. 10.1034/j.1399-0004.2001.6002023.x
- By:
- Publication type:
- Article
Repairing the genomic defect in muscular dystrophy.
- Published in:
- Clinical Genetics, 2000, v. 58, n. 4, p. 265, doi. 10.1034/j.1399-0004.2000.580403.1.x
- By:
- Publication type:
- Article
Aptamers as biomarkers for neurological disorders. Proof of concept in transgenic mice.
- Published in:
- PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190212
- By:
- Publication type:
- Article
Induction of proapoptotic Daxx following ischemic acute kidney injury.
- Published in:
- Kidney International, 2008, v. 74, n. 3, p. 310, doi. 10.1038/ki.2008.192
- By:
- Publication type:
- Article
Protein and oligonucleotide delivery systems for vaginal microbicides against viral STIs.
- Published in:
- Cellular & Molecular Life Sciences, 2015, v. 72, n. 3, p. 469, doi. 10.1007/s00018-014-1756-3
- By:
- Publication type:
- Article
Phase II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in combination with rituximab in patients with recurrent B-cell non-Hodgkin lymphoma.
- Published in:
- British Journal of Haematology, 2008, v. 143, n. 3, p. 355, doi. 10.1111/j.1365-2141.2008.07353.x
- By:
- Publication type:
- Article
Targeting noncoding RNAs in disease.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Degradation product characterization of therapeutic oligonucleotides using liquid chromatography mass spectrometry.
- Published in:
- Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 14, p. 3375, doi. 10.1007/s00216-018-1032-8
- By:
- Publication type:
- Article
Supportive Oligonucleotide Therapy (SOT) as an Alternative Treatment Option in Cancer: A Preliminary Study.
- Published in:
- In Vivo, 2022, v. 36, n. 2, p. 898, doi. 10.21873/invivo.12779
- By:
- Publication type:
- Article
Make or break for first splice-modulating agents.
- Published in:
- Nature Reviews Drug Discovery, 2013, v. 12, n. 11, p. 813, doi. 10.1038/nrd4151
- By:
- Publication type:
- Article
RNA therapeutics: beyond RNA interference and antisense oligonucleotides.
- Published in:
- Nature Reviews Drug Discovery, 2012, v. 11, n. 2, p. 125, doi. 10.1038/nrd3625
- By:
- Publication type:
- Article
In this issue.
- Published in:
- Nature Reviews Drug Discovery, 2011, v. 10, n. 8, p. 557, doi. 10.1038/nrd3513
- Publication type:
- Article
Targeting RNA to treat neuromuscular disease.
- Published in:
- 2011
- By:
- Publication type:
- journal article
Therapeutic potential of Toll-like receptor 9 activation.
- Published in:
- Nature Reviews Drug Discovery, 2006, v. 5, n. 6, p. 471, doi. 10.1038/nrd2059
- By:
- Publication type:
- Article
Poly(glycerol methacrylate)-based degradable nanoparticles for delivery of small interfering RNA.
- Published in:
- Pharmaceutical Development & Technology, 2018, v. 23, n. 4, p. 387, doi. 10.1080/10837450.2017.1312443
- By:
- Publication type:
- Article
New Directions for SMA Therapy.
- Published in:
- Journal of Clinical Medicine, 2018, v. 7, n. 9, p. 251, doi. 10.3390/jcm7090251
- By:
- Publication type:
- Article
Editorial: mongersen in Crohn's disease - a new contribution to the beginning of a long-awaited therapeutic revolution?
- Published in:
- 2016
- By:
- Publication type:
- Editorial
Anti-microRNAs as Novel Therapeutic Agents in the Clinical Management of Alzheimer's Disease.
- Published in:
- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00059
- By:
- Publication type:
- Article