The editorial discusses the synergistic effects of antimicrobial peptides in combating antibiotic resistance, a global health concern. Antimicrobial peptides are natural molecules that play a crucial role in the immune system of various organisms. By combining antimicrobial peptides with traditional antibiotics, researchers aim to enhance their effectiveness in targeting drug-resistant bacteria. Studies highlighted in the editorial demonstrate promising results in developing new treatment strategies to address the antibiotic resistance crisis.