Works matching DE "REGULATORY T cells"

Results: 5000

Treg cell therapy manufacturability: current state of the art, challenges and new opportunities.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1604483

By:

Stoops, Janelle;
Morton, Tara;
Powell, James;
Pace, Amanda L.;
Bluestone, Jeffrey A.

Publication type:

Article

First-in-human evaluation of a no-alpha interleukin–2 mutein: safety and preliminary pharmacodynamic and clinical effect.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589042

By:

Caballero Aguirrechu, Iraida;
Mestre Fernández, Braulio;
Soriano García, Jorge Luis;
Lim Alonso, Nora;
Soto García, Andrés;
Fleites Calvo, Vilma;
Mariño de la Puente, Daines;
Vega Carvajal, Geidy;
Ávila Pérez, Jenny Carolina;
Mendoza Hernández, Ivis;
García López, Elena;
Tarinas Reyes, Alicia;
García-Pérez, Gisela;
Díaz Borges, Claudia;
Ledón Naranjo, Nuris;
Lozada Chang, Sum Lai;
García Vega, Yanelda;
Alvárez Lobaina, Alexis;
Alvárez Cardona, Mabel;
Lorenzo-Luaces Alvárez, Patricia

Publication type:

Article

Uncovering the bequeathing potential of apoptotic mesenchymal stem cells via small extracellular vesicles for its enhanced immunomodulatory and regenerative ability.

Published in:

Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04370-x

By:

Mendiratta, Meenakshi;
Mendiratta, Mohini;
Sharma, Yashvi;
Sahoo, Ranjit Kumar;
Malhotra, Neena;
Mohanty, Sujata

Publication type:

Article

Editorial Comment on "Peritumoral Infiltration of Regulatory T Cells Reduces the Therapeutic Efficacy of Bacillus Calmette–Guérin Therapy for Bladder Carcinoma In Situ".

Published in:

International Journal of Urology, 2025, v. 32, n. 6, p. 747, doi. 10.1111/iju.70089

By:

Takamatsu, Kimiharu

Publication type:

Article

Peritumoral Infiltration of Regulatory T Cells Reduces the Therapeutic Efficacy of Bacillus Calmette–Guérin Therapy for Bladder Carcinoma In Situ.

Published in:

International Journal of Urology, 2025, v. 32, n. 6, p. 737, doi. 10.1111/iju.70044

By:

Fukiage, Yusuke;
Muramoto, Akifumi;
Terada, Naoki;
Kobayashi, Motohiro

Publication type:

Article

Immunomodulatory Functions of Mesenchymal Stem Cells in Tissue Engineering.

Published in:

Archives of Razi Institute, 2025, v. 80, n. 2, p. 413, doi. 10.32592/ARI.2025.80.2.413

By:

Hosseini, Amirhossein;
Abdolmaleki, Arash;
Nahumi, Aida;
Asadi, Asadollah;
Ghanimi, Hussein A.

Publication type:

Article

Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 6, p. 2487, doi. 10.1007/s10067-025-07455-3

By:

Su, Rui;
Wang, Hui;
Li, Baochen;
Wu, Ruihe;
Xie, Yuhuan;
Zi, Xiaoyu;
Fan, Chunxue;
Gao, Chong;
Li, Xiaofeng;
Wang, Caihong

Publication type:

Article

Dysregulation and therapeutic prospects of regulatory T cells in type 1 diabetes.

Published in:

Acta Diabetologica, 2025, v. 62, n. 6, p. 785, doi. 10.1007/s00592-025-02478-3

By:

Syed Khaja, Azharuddin Sajid;
Binsaleh, Naif K.;
Qanash, Husam;
Alshetaiwi, Hamad;
Ginawi, Ibrahim Abdelmageed Mohamed;
Saleem, Mohd

Publication type:

Article

Advancing immunomodulation in organ transplantation: the therapeutic potential of self-assembled rapamycin nanoparticles in allograft rejection.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03498-5

By:

Sun, Ruiqi;
Liang, Zhi;
Wang, Ning;
Chen, Xiaona;
Zhao, Jialing;
Tang, Hong;
Zhao, Wentao;
Wang, Hangxiang;
Zheng, Shusen;
Song, Penghong;
Xie, Haiyang

Publication type:

Article

Tumor-infiltrating lymphocytes in cancer immunotherapy: from chemotactic recruitment to translational modeling.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1601773

By:

Kraja, Fatjona Pupuleku;
Jurisic, Vladimir B.;
Hromić-Jahjefendić, Altijana;
Rossopoulou, Nafsika;
Katsila, Theodora;
Mirjacic Martinovic, Katarina;
De Las Rivas, Javier;
Diaconu, Carmen Cristina;
Szöőr, Árpád

Publication type:

Article

ALG3 as a prognostic biomarker and mediator of PD-1 blockade resistance in hepatocellular carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589153

By:

Tang, Pengju;
Han, Zhenwei;
Zhao, Yiming;
Xu, Tianxin;
Zhang, Yu;
Zhu, Lirong;
Song, Fei;
Gao, Cheng;
Gong, Jinbo;
Cheng, Ji;
Wang, Chenggui;
Wang, Tianlun;
Xu, Jie;
Wang, Yu;
Chen, Zhong

Publication type:

Article

Immunomodulatory effects of alpha vs beta radiopharmaceutical therapy in murine prostate cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1563387

By:

Ferreira, Carolina A.;
Potluri, Hemanth K.;
Mahmoudian, Mojdeh;
Massey, Christopher F.;
Grudzinski, Joseph J.;
Carston, Amanda M.;
Clemons, Nathan B.;
Idrissou, Malick Bio;
Thickens, Anna S.;
Rosenkrans, Zachary T.;
Choi, Cynthia;
Kerr, Caroline P.;
Pinchuk, Anatoly N.;
Kwon, Ohyun;
Jeffery, Justin J.;
Bednarz, Bryan P.;
Morris, Zachary S.;
Weichert, Jamey P.;
McNeel, Douglas G.;
Hernandez, Reinier

Publication type:

Article

Secretory IgA binding to FCRL3 triggers shared inflammatory cytokine secretion by human regulatory T cells and effector T cells.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 5, p. 1, doi. 10.1093/jleuko/qiaf054

By:

Kraus, Zachary;
Birla, Shama;
Powell, Taylor;
Petrovskaya, Svetlana;
Mills, Frederick;
Dement-Brown, Jessica;
Culhane, Casey;
Dokhaee, Kimia;
Tolnay, Mate

Publication type:

Article

Deciphering the deterministic role of TCR signaling in T cell fate determination.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1562248

By:

Qin, Zhen;
Xu, Tao

Publication type:

Article

A new 3-arylbenzofuran derivative EIE-2 reestablishes Treg-dependent tolerance in rheumatoid arthritis by targeting on Syk induced mTOR and PKCθ imbalance.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1524491

By:

Li, Ping;
Yin, Xin;
Wen, Xinzhu;
Li, Xuyu;
Wang, Yuqing;
Zhan, Hongyan;
Che, Hanqing;
Yao, Chunsuo;
Hou, Qi;
Zhang, Ziqian;
Zheng, Ruifang;
Lin, Mingbao

Publication type:

Article

NLRP3 inflammasome expression affects immune cell infiltration and clinical prognosis in Helicobacter pylori infection‑associated gastric cancer.

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 1, p. N.PAG, doi. 10.3892/mmr.2025.13550

By:

Wan, Chuandan;
Xu, Yeqiong;
Zhu, Yanping;
Cao, Xuexian;
Wang, Ping;
Gu, Yulan

Publication type:

Article

β‐Cell dysfunction in diabetes: The role of neuroplastin.

Published in:

Journal of Diabetes Investigation, 2025, v. 16, n. 6, p. 986, doi. 10.1111/jdi.70036

By:

Lee, Moon‐Kyu

Publication type:

Article

Hair follicle-derived melanocyte transplant as a promising treatment strategy for vitiligo.

Published in:

Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04410-6

By:

Fan, Ruirui;
Gao, Jie;
Chen, Jin

Publication type:

Article

Clinical grade expansion protocol for the manufacture of thymus-derived Treg cells for clinical application.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06561-9

By:

Fanelli, Giorgia;
Marks, Philippa;
Aiyengar, Apoorva;
Romano, Marco;
Gooljar, Sakina;
Kumar, Sandeep;
Burch, Michael;
Lombardi, Giovanna

Publication type:

Article

Emerging immune tolerance therapies for neuromyelitis optica spectrum disorder.

Published in:

2025

By:

Carnero Contentti, Edgar;
Correale, Jorge

Publication type:

Editorial

Bulk and single-cell RNA-sequencing analyses revealed potential key genes and the role of CCL19/CCL21-CCR7 axis in hidradenitis suppurativa.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0322565

By:

Lai, Xiaodong;
Yang, Yan;
Zhang, Haini;
Zhang, Chong;
Wang, Meng;
Chen, Wanxin;
Wang, Baoxi;
Yan, Yan

Publication type:

Article

Integrative machine learning identifies robust inflammation-related diagnostic biomarkers and stratifies immune-heterogeneous subtypes in Kawasaki disease.

Published in:

Pediatric Rheumatology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12969-025-01114-2

By:

Wang, Xia;
Zhang, Lin

Publication type:

Article

Identification and validation of mitochondrial endoplasmic reticulum membrane-related genes in atherosclerosis.

Published in:

Mammalian Genome, 2025, v. 36, n. 2, p. 665, doi. 10.1007/s00335-025-10124-0

By:

Wang, Li-Rong;
Zhang, Chun-Xi;
Tian, Lv-Bo;
Huang, Jie;
Jia, Li-Jun;
Tao, Hao;
Yu, Neng-Wei;
Li, Bing-Hu

Publication type:

Article

Study on the impact of CD4<sup>+</sup> T cells and their subsets on relapse in AML patients during remission.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01725-9

By:

Gu, Yingxia;
Dong, Kai;
Deng, Ju;
Qiao, Bianbian;
Liu, Dan;
Xu, Zhifang;
Wang, Hongwei

Publication type:

Article

The abundance of regulatory T cell subsets is associated with the clinical outcomes of sarcoidosis.

Published in:

Modern Rheumatology, 2025, v. 35, n. 3, p. 557, doi. 10.1093/mr/roae106

By:

Kusaka, Katsuhide;
Miyazaki, Yusuke;
Nakayamada, Shingo;
Kubo, Satoshi;
Miyagawa, Ippei;
Satoh-Kanda, Yurie;
Todoroki, Yasuyuki;
Ueno, Masanobu;
Tanaka, Yoshiya

Publication type:

Article

Harnessing Dendritic Cell Function in Hepatocellular Carcinoma: Advances in Immunotherapy and Therapeutic Strategies.

Published in:

Vaccines, 2025, v. 13, n. 5, p. 496, doi. 10.3390/vaccines13050496

By:

Ying, Shiding;
Liu, Haiyan;
Zhang, Yongliang;
Mei, Yu

Publication type:

Article

Evaluation of Immunogenicity of Mycobacterium tuberculosis ag85ab DNA Vaccine Delivered by Pulmonary Administration.

Published in:

Vaccines, 2025, v. 13, n. 5, p. 442, doi. 10.3390/vaccines13050442

By:

Zhao, Haimei;
Zhang, Zhen;
Xue, Yong;
Wang, Nan;
Liu, Yinping;
Ma, Xihui;
Wang, Lan;
Wang, Xiaoou;
Zhang, Danyang;
Zhang, Junxian;
Wu, Xueqiong;
Liang, Yan

Publication type:

Article

The Role of Tregs in the Tumor Microenvironment.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1173, doi. 10.3390/biomedicines13051173

By:

Sato, Yohei

Publication type:

Article

DBI as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1115, doi. 10.3390/biomedicines13051115

By:

Tian, Ting;
Han, Huan;
Huang, Jingtao;
Ma, Jun'e;
Ran, Ruoxi

Publication type:

Article

Diabetic Foot Ulcers: Pathophysiology, Immune Dysregulation, and Emerging Therapeutic Strategies.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1076, doi. 10.3390/biomedicines13051076

By:

Dawi, John;
Tumanyan, Kevin;
Tomas, Kirakos;
Misakyan, Yura;
Gargaloyan, Areg;
Gonzalez, Edgar;
Hammi, Mary;
Tomas, Serly;
Venketaraman, Vishwanath

Publication type:

Article

Construction of Diagnostic Model for Regulatory T Cell-Related Genes in Sepsis Based on Machine Learning.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1060, doi. 10.3390/biomedicines13051060

By:

Wang, Xuesong;
Guo, Zhe;
Wang, Xinrui;
Wang, Zhong

Publication type:

Article

Comprehensive Overview of Cytokine Interplay in Vitiligo: A Decade of Meta-Analyses Systematically Reviewed.

Published in:

Life (2075-1729), 2025, v. 15, n. 5, p. 684, doi. 10.3390/life15050684

By:

Paganelli, Alessia;
Cristofoletti, Cristina;
Moro, Francesco;
Corrente, Alessandra;
Colonna, Laura;
Scala, Emanuele;
Picardo, Mauro

Publication type:

Article

Immunoproteasome Inhibition Impairs Differentiation but Not Survival of T Helper 17 Cells.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 689, doi. 10.3390/cells14100689

By:

Oliveri, Franziska;
Mink, Dennis;
Muchamuel, Tony;
Basler, Michael

Publication type:

Article

Identification of Prognostic Biomarkers of Ovarian High-Grade Serous Carcinoma: A Preliminary Study Using Spatial Transcriptome Analysis and Multispectral Imaging.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 681, doi. 10.3390/cells14100681

By:

Kang, Haeyoun;
Joung, Je-Gun;
Park, Hyun;
Choi, Min Chul;
Koh, Doohyun;
Jeong, Ju-Yeon;
Lee, Jimin;
Kim, Sook-Young;
Jung, Daun;
Hwang, Sohyun;
An, Hee Jung

Publication type:

Article

Molecular Mechanisms in the Carcinogenesis of Oral Squamous Cell Carcinoma: A Literature Review.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 621, doi. 10.3390/biom15050621

By:

Cabral, Laertty Garcia de Sousa;
Martins, Isabela Mancini;
Paulo, Ellen Paim de Abreu;
Pomini, Karina Torres;
Poyet, Jean-Luc;
Maria, Durvanei Augusto

Publication type:

Article

Causal relationship between immune cells and post-viral fatigue syndrome: a Mendelian randomization study.

Published in:

Virology Journal, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12985-025-02809-4

By:

Wang, Zheyi;
Bai, Zetai;
Sun, Yize

Publication type:

Article

Single-cell sequencing atlas construction for tracheobronchial adenoid cystic carcinoma.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06622-z

By:

Teng, Jun;
Hong, Qinyan;
Zou, Heng;
Li, Lei;
Wang, Hongwu

Publication type:

Article

Advances in Regulatory Cell Therapy for Type 1 Diabetes: Emerging Strategies and Future Directions.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202451722

By:

Passerini, Laura;
Forlani, Aurora;
Gregori, Silvia

Publication type:

Article

Treg Control of CD80/CD86 Expression Mediates Immune System Homeostasis.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202551771

By:

Kim, Yong‐Hee;
Panda, Abir K.;
Shevach, Ethan M.

Publication type:

Article

The Human Bone Marrow May Offer an IL‐15‐Dependent Survival Niche for EOMES<sup>+</sup> Tr1‐Like Cells.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202451644

By:

Pulvirenti, Nadia;
Vasco, Chiara;
Righetti, Camilla;
Dadova, Petra;
Boffa, Giacomo;
Laroni, Alice;
Vigo, Tiziana;
Raiola, Anna Maria;
Crosti, Maria Cristina;
Maglie, Stefano;
Valenti, Luca;
Prati, Daniele;
Abrigani, Sergio;
Uccelli, Antonio;
Geginat, Jens

Publication type:

Article

Thymidine kinase 1 indicates resistance to immune checkpoint plus tyrosine kinase inhibition in renal cell carcinoma.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 775, doi. 10.1007/s13402-025-01048-7

By:

Wang, Jiajun;
Xu, Xianglai;
Wang, Ying;
Zhu, Yanjun

Publication type:

Article

Construction and validation of a regulatory T cells-based classification of renal cell carcinoma: an integrated bioinformatic analysis and clinical cohort study.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 591, doi. 10.1007/s13402-024-01030-9

By:

Yao, Yuntao;
Liu, Yifan;
Lu, Bingnan;
Ji, Guo;
Wang, Lei;
Dong, Keqin;
Zhao, Zihui;
Lyu, Donghao;
Wei, Maodong;
Tu, Siqi;
Lyu, Xukun;
Li, Yuanan;
Huang, Runzhi;
Zhou, Wang;
Xu, Guofeng;
Pan, Xiuwu;
Cui, Xingang

Publication type:

Article

Editorial: The role of inflammation and immune control in digestive disease and therapeutic approaches.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1621130

By:

Wang, Zhaoyang;
Wang, Shuai

Publication type:

Article

Spatiotemporal imaging of immune dynamics: rethinking drug efficacy evaluation in cancer immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1609606

By:

Zhang, Xiaowei;
Cheng, Cheng;
Qu, Xiaoyang;
Wang, Pengyun;
Zhang, Dawei;
Dai, Shuhong

Publication type:

Article

Extracorporeal photopheresis as induction therapy in lung transplantation for cystic fibrosis: a pilot randomized trial.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1583460

By:

Righi, Ilaria;
Fenizia, Claudio;
Trabattoni, Daria;
Nosotti, Mario;
Grisorio, Giacomo;
Vanetti, Claudia;
di Tella, Sonia;
Mocellin, Cristina;
Fantini, Norma;
Prati, Daniele;
Morlacchi, Letizia Corinna;
Rossetti, Valeria;
Blasi, Francesco;
Clerici, Mario;
Rosso, Lorenzo Paolo

Publication type:

Article

Recent advances in regulatory immune cells: exploring the world beyond Tregs.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1530301

By:

Shi, Peng;
Yu, Yi;
Xie, Hongwei;
Yin, Xiaofang;
Chen, Xue;
Zhao, Yongfei;
Zhao, Hai

Publication type:

Article

Interplay between cancer-associated fibroblasts and dendritic cells: implications for tumor immunity.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1515390

By:

Mentucci, Fátima María;
Ferrara, María Gracia;
Ercole, Agustina;
Rumie Vittar, Natalia Belén;
Lamberti, María Julia

Publication type:

Article

Granulomatous lymphocytic interstitial lung disease in common variable immune deficiency: an in-depth clinical, immunological, functional and radiological exploration with a focus on its management, challenged by chronic CMV infection.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589052

By:

Moratti, Mattia;
Schifino, Gioacchino;
Baccelli, Francesco;
Ferrari, Simona;
Magrini, Elisabetta;
Bassi, Mirna;
Guerrieri, Aldo;
Zompatori, Maurizio;
Lanari, Marcello;
Conti, Francesca

Publication type:

Article

Immunosuppressive tumor microenvironment in pancreatic cancer: mechanisms and therapeutic targets.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582305

By:

Pan, Da;
Li, Xinyue;
Qiao, Xiao;
Wang, Qiqi

Publication type:

Article

Intrauterine infusion of autologous platelet-rich plasma modulates endometrial immune status and improves pregnancy outcomes in patients with persistent chronic endometritis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1528522

By:

Chen, Xian;
Chen, Mingye;
Liu, Meng;
Qi, Lingbin;
Liu, Zhiqiang;
Chen, Cong;
Liang, Binfa;
Yang, Xiaobing;
Zhang, Tao;
Li, Yuye;
Lian, Ruochun

Publication type:

Article