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Effect of Swine Glyco-humanized Polyclonal Neutralizing Antibody on Survival and Respiratory Failure in Patients Hospitalized With Severe COVID-19: A Randomized, Placebo-Controlled Trial.
- Published in:
- Open Forum Infectious Diseases, 2023, v. 10, n. 11, p. 1, doi. 10.1093/ofid/ofad525
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- Publication type:
- Article
High neutralizing potency of swine glyco‐humanized polyclonal antibodies against SARS‐CoV‐2.
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- European Journal of Immunology, 2021, v. 51, n. 6, p. 1412, doi. 10.1002/eji.202049072
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- Article
Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28.
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- European Journal of Immunology, 2017, v. 47, n. 8, p. 1368, doi. 10.1002/eji.201746923
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- Publication type:
- Article
IL-7 receptor blockade following T cell depletion promotes long-term allograft survival.
- Published in:
- 2014
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- Publication type:
- journal article
IL-7 receptor blockade following T cell depletion promotes long-term allograft survival.
- Published in:
- Journal of Clinical Investigation, 2014, v. 124, n. 4, p. 1723, doi. 10.1172/JCI66287
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- Publication type:
- Article
Targeting the CD80/ CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.
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- Glia, 2015, v. 63, n. 12, p. 2298, doi. 10.1002/glia.22894
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- Publication type:
- Article
Concerted BAG3 and SIRPα blockade impairs pancreatic tumor growth.
- Published in:
- Cell Death Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41420-022-00817-9
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- Publication type:
- Article
XAV-19, a Swine Glyco-Humanized Polyclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Domain, Targets Multiple Epitopes and Broadly Neutralizes Variants.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.761250
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- Article
Les futures générations d'anticorps modulateurs des points de contrôle de la réponse immunitaire.
- Published in:
- Médecine Sciences, 2019, v. 35, n. 12, p. 966, doi. 10.1051/medsci/2019193
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- Publication type:
- Article
Expression of Heme Oxygenase-1 in Neural Stem/Progenitor Cells as a Potential Mechanism to Evade Host Immune Response.
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- Stem Cells, 2012, v. 30, n. 10, p. 2342, doi. 10.1002/stem.1199
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- Publication type:
- Article
A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice.
- Published in:
- Diabetologia, 2018, v. 61, n. 8, p. 1811, doi. 10.1007/s00125-018-4638-7
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- Publication type:
- Article
Selective CD28 antagonist prevents Aldara-induced skin inflammation in non-human primates.
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- Experimental Dermatology, 2016, v. 25, n. 3, p. 233, doi. 10.1111/exd.12891
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- Publication type:
- Article
Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats.
- Published in:
- Scientific Reports, 2016, p. 31455, doi. 10.1038/srep31455
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- Publication type:
- Article
CD28 Costimulation of T Helper 1 Cells enhances cytokine release In Vivo.
- Published in:
- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01060
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- Publication type:
- Article
Targeting CD28, CTLA-4 and PD-L1 Costimulation Differentially Controls Immune Synapses and Function of Human Regulatory and Conventional T-Cells.
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- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083139
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- Publication type:
- Article
Interleukin 7 receptor α as a potential therapeutic target in transplantation.
- Published in:
- Archivum Immunologiae & Therapiae Experimentalis, 2009, v. 57, n. 4, p. 253, doi. 10.1007/s00005-009-0036-7
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- Publication type:
- Article
Genetic Engineering in the Pig: Gene Knockout and Alternative Techniques.
- Published in:
- Annals of the New York Academy of Sciences, 1998, v. 862, n. 1, p. 28, doi. 10.1111/j.1749-6632.1998.tb09114.x
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- Publication type:
- Article
Transcriptional and posttranscriptional regulation of α1,3‐galactosyltransferase in activated endothelial cells results in decreased expression of Galα1,3Gal.
- Published in:
- Glycobiology, 1998, v. 8, n. 5, p. 481, doi. 10.1093/glycob/8.5.481
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- Publication type:
- Article
IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.
- Published in:
- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06804-y
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- Publication type:
- Article
Local control of the host immune response performed with mesenchymal stem cells: perspectives for functional intracerebral xenotransplantation.
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- Journal of Cellular & Molecular Medicine, 2015, v. 19, n. 1, p. 124, doi. 10.1111/jcmm.12414
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- Publication type:
- Article
Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation.
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- Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 8b, p. 2547, doi. 10.1111/j.1582-4934.2009.00657.x
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- Publication type:
- Article
Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized, double-blinded, placebo-controlled phase 2 (2a and 2b) trial.
- Published in:
- 2021
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- Publication type:
- journal article
Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders.
- Published in:
- Antibodies (2073-4468), 2017, v. 6, n. 4, p. 19, doi. 10.3390/antib6040019
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- Publication type:
- Article
CD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity.
- Published in:
- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01152
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- Publication type:
- Article
Inducing CTLA-4-Dependent Immune Regulation by Selective CD28 Blockade Promotes Regulatory T Cells in Organ Transplantation.
- Published in:
- Science Translational Medicine, 2010, v. 2, n. 17, p. 1, doi. 10.1126/scitranslmed.3000116
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- Publication type:
- Article
Novel CD28 antagonist mPEG PV1-Fab’ mitigates experimental autoimmune uveitis by suppressing CD4+ T lymphocyte activation and IFN-γ production.
- Published in:
- PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0171822
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- Publication type:
- Article
Control of transplant tolerance and intragraft regulatory T cell localization by CCL5.
- Published in:
- 2012
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- Publication type:
- Abstract
Evaluation of FR104, a Treg sparing antagonist anti-CD28 monovalent Fab' antibody in kidney transplantation in non-human primates.
- Published in:
- 2012
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- Publication type:
- Abstract
Inhibition of cystathionine-g-lyase controls interleukin-12 production by dendritic cells, delayed-type hypersensitivity and transplant rejection.
- Published in:
- 2012
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- Publication type:
- Abstract
Antagonist properties of monoclonal antibodies to human CD28: role of valency and heavy-chain constant domain.
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- 2012
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- Publication type:
- Abstract
Differential regulation of motility and immune synapses by CD28/ CTLA-4 costimulation in effector and regulatory T cells.
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- 2012
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- Publication type:
- Abstract
Graft versus host disease in humanized mice is differentially controlled by CD28 and CD80/86 antagonists.
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- 2012
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- Publication type:
- Abstract
Lack of Immunotoxicity After Regional Intravenous (RI) Delivery of rAAV to Nonhuman Primate Skeletal Muscle.
- Published in:
- Molecular Therapy, 2010, v. 18, n. 1, p. 151, doi. 10.1038/mt.2009.251
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- Publication type:
- Article
974. Constitutive Expression of a Mutated Form of CTLA4Ig after Gene Transfer Is Well Tolerated and Prevents Immune Responses Against an Immunogenic Transgene in Nonhuman Primates.
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- Molecular Therapy, 2006, v. 13, p. S375, doi. 10.1016/j.ymthe.2006.08.1067
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- Publication type:
- Article
Induction of regulatory cells and control of cellular but not vascular rejection by costimulation blockade in hamster-to-rat heart xenotransplantation.
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- Xenotransplantation, 2007, v. 14, n. 1, p. 25, doi. 10.1111/j.1399-3089.2006.00361.x
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- Publication type:
- Article
Human xenoreactive natural antibodies of the IgM isotype activate pig endothelial cells.
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- Xenotransplantation, 1994, v. 1, n. 1, p. 17, doi. 10.1111/j.1399-3089.1994.tb00046.x
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- Publication type:
- Article
Reply to 'Biologics in organ transplantation'.
- Published in:
- Transplant International, 2013, v. 26, n. 4, p. e25, doi. 10.1111/tri.12009
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- Publication type:
- Article
A more selective costimulatory blockade of the CD28-B7 pathway.
- Published in:
- Transplant International, 2011, v. 24, n. 1, p. 2, doi. 10.1111/j.1432-2277.2010.01176.x
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- Publication type:
- Article
Autoimmune responses against renal tissue proteins in long-term surviving allograft recipients.
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- Transplant International, 2009, v. 22, n. 11, p. 1091, doi. 10.1111/j.1432-2277.2009.00923.x
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- Publication type:
- Article
Depleting T-cell subpopulations in organ transplantation.
- Published in:
- Transplant International, 2009, v. 22, n. 5, p. 509, doi. 10.1111/j.1432-2277.2008.00788.x
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- Publication type:
- Article
Anti-SARS-CoV-2 glyco-humanized polyclonal antibody XAV-19: phase II/III randomized placebo-controlled trial shows acceleration to recovery for mild to moderate patients with COVID-19.
- Published in:
- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1330178
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- Publication type:
- Article
Cystathionine‐gamma‐lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.
- Published in:
- Cancer Science, 2021, v. 112, n. 5, p. 1723, doi. 10.1111/cas.14862
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- Publication type:
- Article
Myeloid-derived suppressor cells: mechanisms of action and recent advances in their role in transplant tolerance.
- Published in:
- Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00208
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- Publication type:
- Article
Myeloid-Derived Suppressor Cells: Mechanisms of Action and recent advances in their role in transplant tolerance.
- Published in:
- Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00208
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- Publication type:
- Article