Works matching DE "PROGRANULIN"

Results: 375

Early-Phase Trial Launches of VES001 for Gene-Related Frontotemporal Dementia.

Published in:: Patient Care (Online), 2025, p. 7
Publication type:: Article

Assessment The Serum Progranulin Level As A Biomarker For Retinopathy In Type 2 Diabetic Patients.

Published in:

Zagazig University Medical Journal, 2023, v. 29, p. 99, doi. 10.21608/zumj.2020.33166.1881

By:

Sheta, Yasser Samir;
Abdelfattahh, Nermin Raafat;
Wahid, Islam Maher;
Habibi, Ismaeil Abdalla

Publication type:

Article

Serum level of progranulin in Egyptian acute myeloid leukemia patients at diagnosis and after chemotherapy treatment.

Published in:

Egyptian Journal of Haematology, 2022, v. 47, n. 2, p. 94, doi. 10.4103/ejh.ejh_61_21

By:

Mohamed, Inas;
Azzazi, Mohamed;
El Afifi, Amal;
Hegab, Hany;
El Ghammaz, Amro;
Fathy, Rasha

Publication type:

Article

The Emerging Roles of MicroRNAs in the Pathogenesis of Frontotemporal Dementia-Amyotrophic Lateral Sclerosis (FTD-ALS) Spectrum Disorders.

Published in:

Journal of Neurogenetics, 2014, v. 28, n. 1/2, p. 30, doi. 10.3109/01677063.2013.876021

By:

Gascon, Eduardo;
Gao, Fen-Biao

Publication type:

Article

Antiphotoaging Effects of Damiana (Turnera diffusa) Leaves Extract via Regulation AP-1 and Nrf2/ARE Signaling Pathways.

Published in:

Plants (2223-7747), 2022, v. 11, n. 11, p. 1486, doi. 10.3390/plants11111486

By:

Kim, Minseon;
Ha, Lee-Keun;
Oh, Sarang;
Fang, Minzhe;
Zheng, Shengdao;
Bellere, Arce D.;
Jeong, Jeehaeng;
Yi, Tae-Hoo

Publication type:

Article

Elevated levels of extracellular vesicles in progranulin‐deficient mice and FTD‐GRN Patients.

Published in:

Annals of Clinical & Translational Neurology, 2020, v. 7, n. 12, p. 2433, doi. 10.1002/acn3.51242

By:

Arrant, Andrew E.;
Davis, Skylar E.;
Vollmer, Rachael M.;
Murchison, Charles F.;
Mobley, James A.;
Nana, Alissa L.;
Spina, Salvatore;
Grinberg, Lea T.;
Karydas, Anna M.;
Miller, Bruce L.;
Seeley, William W.;
Roberson, Erik D.

Publication type:

Article

Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment.

Published in:

Annals of Clinical & Translational Neurology, 2018, v. 5, n. 5, p. 616, doi. 10.1002/acn3.560

By:

Cooper, Yonatan A.;
Nachun, Daniel;
Dokuru, Deepika;
Yang, Zhongan;
Karydas, Anna M.;
Serrero, Ginette;
Yue, Binbin;
Alzheimer's Disease Neuroimaging Initiative;
Boxer, Adam L.;
Miller, Bruce L.;
Coppola, Giovanni

Publication type:

Article

Hyper-religiosity and visual hallucinations in a patient with frontotemporal dementia carrying a double variant in GRN gene.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2022, v. 23, n. 1/2, p. 87, doi. 10.1080/21678421.2021.1946087

By:

Morelli, Maurizio;
Quattrone, Andrea;
Arabia, Gennarina;
Manna, Ida;
Gambardella, Antonio;
Quattrone, Aldo

Publication type:

Article

Late onset bipolar disorder and frontotemporal dementia with mutation in progranulin gene: a case report.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2017, v. 18, n. 7/8, p. 624, doi. 10.1080/21678421.2017.1339716

By:

Rubino, Elisa;
Vacca, Alessandro;
Gallone, Salvatore;
Govone, FLORA;
Zucca, Milena;
Gai, Annalisa;
Ferrero, Patrizia;
Fenoglio, Pierpaola;
Giordana, Maria Teresa;
Rainero, Innocenzo

Publication type:

Article

Diagnostic and prognostic significance of neurofilament light chain NF-L, but not progranulin and S100B, in the course of amyotrophic lateral sclerosis: Data from the German MND-net.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2017, v. 18, n. 1/2, p. 112, doi. 10.1080/21678421.2016.1241279

By:

Steinacker, Petra;
Huss, André;
Mayer, Benjamin;
Grehl, Torsten;
Grosskreutz, Julian;
Borck, Guntram;
Kuhle, Jens;
Lulé, Dorothée;
Meyer, Thomas;
Oeckl, Patrick;
Petri, Susanne;
Weishaupt, Jochen;
Ludolph, Albert C.;
Otto, Markus

Publication type:

Article

C9orf72 mutations may be rare in frontotemporal lobar degeneration patients in India.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2016, v. 17, n. 1/2, p. 151, doi. 10.3109/21678421.2015.1074706

By:

Mukherjee, Odity;
Das, Gopal;
Sen, Somdutta;
Dutt, Aparna;
Alladi, Suvarna;
Ghosh, Amitabha

Publication type:

Article

Levels of DEFA1, Progranulin, and NRG4 in Patients with Autonomic Neuropathy: Potential Biomarkers for Diagnosis and Prognosis.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 3, p. 169, doi. 10.3390/metabo15030169

By:

Nikolova, Diana;
Kamenov, Zdravko;
Hristova, Julieta;
Gateva, Antoaneta Trifonova

Publication type:

Article

Adipokines, Vitamin D, and Selected Inflammatory Biomarkers among Parkinson's Disease Patients with and without Dyskinesia: A Preliminary Examination.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 2, p. 106, doi. 10.3390/metabo14020106

By:

Milanowski, Jan;
Nuszkiewicz, Jarosław;
Lisewska, Beata;
Lisewski, Paweł;
Szewczyk-Golec, Karolina

Publication type:

Article

Progranulin promotes Temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness.

Published in:

Oncogene, 2015, v. 34, n. 14, p. 1853, doi. 10.1038/onc.2014.92

By:

Bandey, I;
Chiou, S-H;
Huang, A-P;
Tsai, J-C;
Tu, P-h

Publication type:

Article

Progranulin Deficient Mice Develop Nephrogenic Diabetes Insipidus.

Published in:

Aging & Disease, 2018, v. 9, n. 5, p. 817, doi. 10.14336/AD.2017.1127

By:

Hardt, Stefanie;
Valek, Lucie;
Jinyang Zeng-Brouwers;
Wilken-Schmitz, Annett;
Schaefer, Liliana;
Tegeder, Irmgard

Publication type:

Article

The role of progranulin in diabetes and kidney disease.

Published in:

Diabetology & Metabolic Syndrome, 2015, v. 7, p. 1, doi. 10.1186/s13098-015-0112-6

By:

Nicoletto, Bruna Bellincanta;
Canani, Luis Henrique

Publication type:

Article

Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 395, doi. 10.2147/OTT.S155511

By:

Daya, Minerva;
Loilome, Watcharin;
Techasen, Anchalee;
Thanee, Malinee;
Sa-Ngiamwibool, Prakasit;
Titapun, Attapol;
Yongvanit, Puangrat;
Namwat, Nisana

Publication type:

Article

Progranulin gene variability influences the risk for bipolar I disorder, but not bipolar II disorder.

Published in:

Bipolar Disorders, 2014, v. 16, n. 7, p. 769, doi. 10.1111/bdi.12180

By:

Galimberti, Daniela;
Prunas, Cecilia;
Paoli, Riccardo A;
Dell'Osso, Bernardo;
Fenoglio, Chiara;
Villa, Chiara;
Palazzo, Carlotta;
Cigliobianco, Michela;
Camuri, Giulia;
Serpente, Maria;
Scarpini, Elio;
Altamura, A Carlo

Publication type:

Article

Phenotypic Variation of Autosomal-Dominant Corticobasal Degeneration.

Published in:

European Neurology, 2012, v. 67, n. 3, p. 142, doi. 10.1159/000334731

By:

Jung, Hans H.;
Bremer, Juliane;
Streffer, Johannes;
Virdee, Kanwar;
Spillantini, Maria Grazia;
Crowther, R. Anthony;
Brugger, Peter;
Van Broeckhoven, Christine;
Aguzzi, Adriano;
Tolnay, Markus

Publication type:

Article

TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III.

Published in:

Molecular Brain, 2015, v. 8, p. 1, doi. 10.1186/s13041-015-0177-z

By:

Mi-Hee Jun;
Jeong-Ho Han;
Yu-Kyung Lee;
Deok-Jin Jang;
Bong-Kiun Kaang;
Jin-A Lee

Publication type:

Article

Association between progranulin serum levels and dietary intake.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0202149

By:

Nicoletto, Bruna Bellincanta;
Sarmento, Roberta Aguiar;
Pedrollo, Elis Forcellini;
Krolikowski, Thaiana Cirino;
Canani, Luis Henrique

Publication type:

Article

Progranulin serum levels in human kidney transplant recipients: A longitudinal study.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0192959

By:

Nicoletto, Bruna Bellincanta;
Pedrollo, Elis Forcellini;
Carpes, Larissa Salomoni;
Coloretti, Natália Gomes;
Krolikowski, Thaiana Cirino;
Souza, Gabriela Corrêa;
Gonçalves, Luiz Felipe Santos;
Manfro, Roberto Ceratti;
Canani, Luis Henrique

Publication type:

Article

The Role of Progranulin (PGRN) in the Pathogenesis of Ischemic Stroke.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 7, p. 3435, doi. 10.1007/s10571-023-01396-8

By:

Purrahman, Daryush;
Shojaeian, Ali;
Poniatowski, Łukasz A.;
Piechowski-Jóźwiak, Bartłomiej;
Mahmoudian-Sani, Mohammad-Reza

Publication type:

Article

Development of a Cell-Based Assay to Assess Binding of the proNGF Prodomain to Sortilin.

Published in:

Cellular & Molecular Neurobiology, 2018, v. 38, n. 4, p. 827, doi. 10.1007/s10571-017-0558-1

By:

Malik, Ibrahim;
Christensen, Søren;
Stavenhagen, Jeffrey B.;
Dietz, Gunnar P. H.

Publication type:

Article

Progranulin Preserves Autophagy Flux and Mitochondrial Function in Rat Cortical Neurons Under High Glucose Stress.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.874258

By:

Dedert, Cass;
Mishra, Vandana;
Aggarwal, Geetika;
Nguyen, Andrew D.;
Fenglian Xu

Publication type:

Article

Learning and memory with neuropathic pain: impact of old age and progranulin deficiency.

Published in:

Frontiers in Behavioral Neuroscience, 2013, v. 7, p. 1, doi. 10.3389/fnbeh.2013.00174

By:

Albuquerque, Boris;
Häussler, Annett;
Vannoni, Elisabetta;
Wolfer, David P.;
Tegeder, Irmgard

Publication type:

Article

Reduced miR-659-3p Levels Correlate with Progranulin Increase in Hypoxic Conditions: Implications for Frontotemporal Dementia.

Published in:

Frontiers in Molecular Neuroscience, 2016, p. 1, doi. 10.3389/fnmol.2016.00031

By:

Piscopo, Paola;
Grasso, Margherita;
Fontana, Francesca;
Crestini, Alessio;
Puopolo, Maria;
Del Vescovo, Valerio;
Venerosi, Aldina;
Calamandrei, Gemma;
Vencken, Sebastian F.;
Greene, Catherine M.;
Confaloni, Annamaria;
Denti, Michela A.;
Asif, Abdul R.;
Galimberti, Daniela

Publication type:

Article

Progranulin as a candidate biomarker for therapeutic trial in patients with ALS and FTLD.

Published in:

Journal of Neural Transmission, 2016, v. 123, n. 3, p. 289, doi. 10.1007/s00702-015-1486-1

By:

Feneberg, Emily;
Steinacker, Petra;
Volk, Alexander;
Weishaupt, Jochen;
Wollmer, Marc;
Boxer, Adam;
Tumani, Hayrettin;
Ludolph, Albert;
Otto, Markus

Publication type:

Article

Clinical phenotypes and genetic biomarkers of FTLD.

Published in:

Journal of Neural Transmission, 2012, v. 119, n. 7, p. 851, doi. 10.1007/s00702-012-0804-0

By:

Galimberti, Daniela;
Scarpini, Elio

Publication type:

Article

Nicorandil treatment improves survival and spatial learning in aged granulin knockout mice.

Published in:

Brain Pathology, 2025, v. 35, n. 3, p. 1, doi. 10.1111/bpa.13312

By:

Niedowicz, Dana M.;
Wang, Wang‐Xia;
Prajapati, Paresh;
Zhong, Yu;
Fister, Shuling;
Rogers, Colin B.;
Sompol, Pradoldej;
Powell, David K.;
Patel, Indumati;
Norris, Christopher M.;
Saatman, Kathryn E.;
Nelson, Peter T.

Publication type:

Article

Neurodegeneration and NLRP3 inflammasome expression in the anterior thalamus of SOD1(G93A) ALS mice.

Published in:

Brain Pathology, 2018, v. 28, n. 1, p. 14, doi. 10.1111/bpa.12467

By:

Debye, Berthold;
Schmülling, Lena;
Zhou, Lepu;
Rune, Gabriele;
Beyer, Cordian;
Johann, Sonja

Publication type:

Article

Alzheimer neuropathology without frontotemporal lobar degeneration hallmarks ( TAR DNA-binding protein 43 inclusions) in missense progranulin mutation Cys139 Arg.

Published in:

Brain Pathology, 2018, v. 28, n. 1, p. 72, doi. 10.1111/bpa.12480

By:

Redaelli, Veronica;
Rossi, Giacomina;
Maderna, Emanuela;
Kovacs, Gabor G.;
Piccoli, Elena;
Caroppo, Paola;
Cacciatore, Francesca;
Spinello, Sonia;
Grisoli, Marina;
Sozzi, Giuliano;
Salmaggi, Andrea;
Tagliavini, Fabrizio;
Giaccone, Giorgio

Publication type:

Article

Understanding the role of progranulin in Alzheimer's disease.

Published in:

Nature Medicine, 2014, v. 20, n. 10, p. 1099, doi. 10.1038/nm.3712

By:

D'Alton, Simon;
Lewis, Jada

Publication type:

Article

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.

Published in:

Nature Medicine, 2014, v. 20, n. 10, p. 1157, doi. 10.1038/nm.3672

By:

Minami, S Sakura;
Min, Sang-Won;
Krabbe, Grietje;
Wang, Chao;
Zhou, Yungui;
Asgarov, Rustam;
Li, Yaqiao;
Martens, Lauren H;
Elia, Lisa P;
Ward, Michael E;
Mucke, Lennart;
Farese, Robert V;
Gan, Li

Publication type:

Article

Pathological correlates of white matter hyperintensities in a case of progranulin mutation associated frontotemporal dementia.

Published in:

2018

By:

Woollacott, Ione O.C.;
Bocchetta, Martina;
Sudre, Carole H.;
Ridha, Basil H.;
Strand, Catherine;
Courtney, Robert;
Ourselin, Sebastien;
Cardoso, M. Jorge;
Warren, Jason D.;
Rossor, Martin N.;
Revesz, Tamas;
Fox, Nick C.;
Holton, Janice L.;
Lashley, Tammaryn;
Rohrer, Jonathan D.

Publication type:

journal article

Progranulin and Vaspin as Potential Novel Markers in the Etiology of Type 1 Diabetes in Children.

Published in:

Medicina (1010660X), 2024, v. 60, n. 7, p. 1165, doi. 10.3390/medicina60071165

By:

Jakubek-Kipa, Katarzyna;
Galiniak, Sabina;
Mazur, Artur

Publication type:

Article

Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris.

Published in:

Cardiovascular Diabetology, 2014, v. 13, n. 1, p. 2, doi. 10.1186/1475-2840-13-14

By:

Kyung Mook Choi;
Soon Young Hwang;
Ho Chel Hong;
Hae Yoon Choi;
Hye Jin Yoo;
Byung-Soo Youn;
Sei Hyun Baik;
Hong Seog Seo

Publication type:

Article

Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations.

Published in:: BMC Genomics, 2011, v. 12, n. Suppl 2, p. 527, doi. 10.1186/1471-2164-12-527
Publication type:: Article

PGRN inhibits CD8<sup>+</sup>T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM.

Published in:

Cancer Immunology, Immunotherapy, 2024, v. 73, n. 5, p. 1, doi. 10.1007/s00262-024-03655-z

By:

Zhou, Ting;
Qian, Husun;
Zhang, Dian;
Fang, Wenli;
Yao, MengLi;
Shi, He;
Chen, Tingmei;
Chai, Chengsen;
Guo, Bianqin

Publication type:

Article

High Serum Progranulin Levels in COVID-19 Patients: A Pilot Study.

Published in:

Biochemistry (00062979), 2022, v. 87, n. 3, p. 207, doi. 10.1134/S0006297922030026

By:

Özgeriş, Fatma B.;
Koçak, Ömer F.;
Kurt, Nezahat;
Parlak, Emine;
Yüce, Neslihan;
Keleş, Mevlüt S.

Publication type:

Article

Can serum progranulin levels be a biomarker following gastric ulcer therapy?

Published in:

Gastroenterology Review / Przegląd Gastroenterologiczny, 2018, v. 13, n. 4, p. 313, doi. 10.5114/pg.2018.79812

By:

Aksoy, Evrim Kahramanoğlu;
Sapmaz, Ferdane;
Doğan, Özlem;
Albuz, Özgür;
Uzman, Metin;
Nazlıgül, Yaşar

Publication type:

Article

Progranulin and tumor necrosis factor-alpha in lean polycystic ovary syndrome patients.

Published in:

Gynecological Endocrinology, 2021, v. 37, n. 10, p. 925, doi. 10.1080/09513590.2021.1958311

By:

Uzdogan, Andac;
Kuru Pekcan, Meryem;
Cil, Aylin Pelin;
Kisa, Ucler;
Akbiyik, Filiz

Publication type:

Article

Single-cell multimodal analysis in a case with reduced penetrance of Progranulin-Frontotemporal Dementia.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01234-2

By:

Natarajan, Karthick;
Eisfeldt, Jesper;
Hammond, Maria;
Laffita-Mesa, José Miguel;
Patra, Kalicharan;
Khoshnood, Behzad;
Öijerstedt, Linn;
Graff, Caroline

Publication type:

Article

Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01158-x

By:

Frew, Jonathan;
Nygaard, Haakon Berge

Publication type:

Article

AZP2006, a new promising treatment for Alzheimer's and related diseases.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-94708-1

By:

Callizot, N.;
Estrella, C.;
Burlet, S.;
Henriques, A.;
Brantis, C.;
Barrier, M.;
Campanari, M. L.;
Verwaerde, P.

Publication type:

Article

Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases.

Published in:

Cells (2073-4409), 2019, v. 8, n. 3, p. 230, doi. 10.3390/cells8030230

By:

Mendsaikhan, Anarmaa;
Tooyama, Ikuo;
Walker, Douglas G.

Publication type:

Article

Investigating the role and regulation of GPNMB in progranulindeficient macrophages.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1417836

By:

Gillett, Drew A.;
Neighbarger, Noelle K.;
Cole, Cassandra;
Wallings, Rebecca L.;
Tansey, Malú Gámez

Publication type:

Article

Investigating the role and regulation of GPNMB in progranulin-deficient macrophages.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1417836

By:

Gillett, Drew A.;
Neighbarger, Noelle K.;
Cole, Cassandra;
Wallings, Rebecca L.;
Tansey, Malú Gámez

Publication type:

Article

Pharmacotherapy for Frontotemporal Dementia.

Published in:

2021

By:

Khoury, Rita;
Liu, Yu;
Sheheryar, Quratulanne;
Grossberg, George T.

Publication type:

journal article

Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27088-9

By:

Cheung, Phyllis F.;
Yang, JiaJin;
Fang, Rui;
Borgers, Arianna;
Krengel, Kirsten;
Stoffel, Anne;
Althoff, Kristina;
Yip, Chi Wai;
Siu, Elaine H. L.;
Ng, Linda W. C.;
Lang, Karl S.;
Cham, Lamin B.;
Engel, Daniel R.;
Soun, Camille;
Cima, Igor;
Scheffler, Björn;
Striefler, Jana K.;
Sinn, Marianne;
Bahra, Marcus;
Pelzer, Uwe

Publication type:

Article