Works matching DE "BRCA genes"

Results: 4739

Reply to: "Comments on the paper 'Extensive epigenomic dysregulation is a hallmark of homologous recombination deficiency in triple‐negative breast cancer' by Y. Chen et al.".

Published in:

International Journal of Cancer, 2025, v. 157, n. 3, p. 590, doi. 10.1002/ijc.35434

By:

Chen, Youdinghuan;
Salas, Lucas A.;
Marotti, Jonathan D.;
Jenkins, Nicole P.;
Cheng, Chao;
Miller, Todd W.;
Kettenbach, Arminja N.;
Christensen, Brock C.

Publication type:

Article

Comments on the paper "Extensive epigenomic dysregulation is a hallmark of homologous recombination deficiency in triple‐negative breast cancer" by Y. Chen et al.

Published in:

International Journal of Cancer, 2025, v. 157, n. 3, p. 588, doi. 10.1002/ijc.35433

By:

Lønning, Per Eystein;
Nikolaienko, Oleksii;
Knappskog, Stian

Publication type:

Article

SENP5 drives breast cancer progression through deSUMOYlation of CDK1.

Published in:

Breast Cancer Research, 2025, v. 27, n. 1, p. 1, doi. 10.1186/s13058-025-02054-1

By:

Chen, Cui;
Yao, Hanming;
Jie, Haiqing;
Liang, Zhenkang;
Zhang, Yuxuan;
Wen, Xinyun;
Zhao, Jinze;
Xiong, Huiping;
Zheng, Zongheng;
Wu, Juekun

Publication type:

Article

Significantly increased load of hereditary cancer-linked germline variants in infertile men Open Access.

Published in:

Human Reproduction Open, 2025, v. 2025, n. 2, p. 1, doi. 10.1093/hropen/hoaf008

By:

Valkna, Anu;
Juchnewitsch, Anna-Grete;
Põlluaas, Lisanna;
Lillepea, Kristiina;
Tjagur, Stanislav;
Dutta, Avirup;
Pomm, Kristjan;
Punab, Margus;
Laan, Maris

Publication type:

Article

Sexual dysfunction and body image in BRCA mutation carriers before and after risk-reducing salpingo-oophorectomy: a cross-sectional study Open Access.

Published in:

Journal of Sexual Medicine, 2025, v. 22, n. 6, p. 1062, doi. 10.1093/jsxmed/qdaf078

By:

Sorbi, Flavia;
Farsi, Elisa;
Maseroli, Elisa;
Orlandi, Gretha;
Giglioni, Claudia;
Saso, Srdjan;
Bogani, Giorgio;
Fambrini, Massimiliano;
Vignozzi, Linda;
Petraglia, Felice

Publication type:

Article

A lung cancer mouse model system based on an inbred C3H strain: Ultrasound imaging, pathological analysis, and proteomic biomarker identification.

Published in:

Veterinary World, 2025, v. 18, n. 5, p. 1101, doi. 10.14202/vetworld.2025.1101-1108

By:

Kustiati, Ulayatul;
Widayati, Wahyu Tri;
Kusindarta, Dwi Liliek;
Agung Nugrahaningsih, Dwi Aris;
Aliffia, Dinda;
Tina Sanjaya, Wilda Bunga;
Wihadmadyatami, Hevi

Publication type:

Article

Editorial: A year in review: discussions in human and medical genomics.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1618183

By:

Freidin, Maxim B.;
Roach, Jared C.

Publication type:

Article

Genomic landscape and homologous recombination repair deficiency signature in stage I-III and de novo stage IV primary breast cancers.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf089

By:

Jeon, June E;
Chen, Kuei-Ting;
Madison, Russell;
Schrock, Alexa B;
Sokol, Ethan;
Levy, Mia A;
Rozenblit, Mariya;
Huang, Richard S P;
Pusztai, Lajos

Publication type:

Article

Oncotype DX Recurrence Score and Germline BRCA Variants in Patients with HR-Positive/HER2-Negative Early Breast Cancer: A Retrospective Observational Study.

Published in:

Oncology & Therapy, 2025, v. 13, n. 2, p. 363, doi. 10.1007/s40487-025-00332-8

By:

Morganti, Stefania;
Khan, Rabia A.;
Berrocal-Almanza, Luis C.;
Miranda, Miguel;
Luo, Linlin;
Xu, Xiaoqing;
Partridge, Ann H.;
Lynce, Filipa

Publication type:

Article

An Exploration Into the Impact of the BRCA 1 and 2 Genetic Mutations Diagnosis on Women's Perceptions of Motherhood: A Thematic Analysis.

Published in:

Women's Reproductive Health, 2025, v. 12, n. 2, p. 507, doi. 10.1080/23293691.2025.2479489

By:

Lidstone, Rebecca;
Stubbings, Daniel R.;
McKnight, Christine

Publication type:

Article

Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1058, doi. 10.3390/biomedicines13051058

By:

Singh, Sharda P.;
Dhanasekara, Chathurika S.;
Melkus, Michael W.;
Bose, Chhanda;
Khan, Sonia Y.;
Sardela de Miranda, Flavia;
Mahecha, Maria F.;
Gukhool, Prrishti J.;
Tonk, Sahil S.;
Jun, Se-Ran;
Uygun, Sahra;
Layeequr Rahman, Rakhshanda

Publication type:

Article

Construction and validation of antibody dependent cell phagocytosis related risk model in breast cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03825-8

By:

Jiang, Xiwei;
Zhang, Jinqing;
Liu, Xiaoming

Publication type:

Article

Real-World Analysis of HRD Assay Variability in High-Grade Serous Ovarian Cancer: Impacts of BRCA1/2 Mutation Subtypes on HRD Assessment.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 745, doi. 10.3390/biom15050745

By:

Scaglione, Giovanni Luca;
Lombardo, Valentina;
Polano, Maurizio;
Scandurra, Giuseppa;
Pettinato, Angela;
Giunta, Corrado;
Iemmolo, Rosario;
Scollo, Paolo;
Capoluongo, Ettore D.

Publication type:

Article

Elucidating the Prognostic and Therapeutic Implications of Insulin Resistance Genes in Breast Cancer: A Machine Learning-Powered Analysis.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 539, doi. 10.3390/biology14050539

By:

Wei, Lengyun;
Li, Dashuai;
Chen, Hongjin;
Pu, Yajing;
Wang, Qun;
Li, Jintao;
Zhou, Meng;
Liu, Chenfeng;
Long, Pengpeng

Publication type:

Article

A Multi‐Level Analysis of Barriers and Promoting Factors to Cascade Screening Uptake Among Male Relatives of BRCA1/2 Carriers: A Qualitative Study.

Published in:

Psycho-Oncology, 2025, v. 34, n. 5, p. 1, doi. 10.1002/pon.70160

By:

Ongaro, G.;
Hamilton, J. G.;
Groner, V.;
Hay, J. L.;
Calvello, M.;
Oliveri, S.;
Bonanni, B.;
Feroce, I.;
Pravettoni, G.

Publication type:

Article

Impedimetric Detection of Breast Cancer‐Related BRCA1 Gene Using Molecular Imprinted Polymer Modified ITO Electrode.

Published in:

Polymers for Advanced Technologies, 2025, v. 36, n. 5, p. 1, doi. 10.1002/pat.70189

By:

Majd, Samira Mansouri;
Mirzapour, Fatemeh;
Shamsipur, Mojtaba

Publication type:

Article

Storage Time and DNA Quality Determine BRCA1/2 Sequencing Success in Prostate Cancer: A Multicentre Analysis with Therapeutic Implications.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1705, doi. 10.3390/cancers17101705

By:

Vescovo, Mariavittoria;
Raspollini, Maria Rosaria;
Nibid, Lorenzo;
Castiglione, Francesca;
Nardi, Eleonora;
de Biase, Dario;
Massari, Francesco;
Giunchi, Francesca;
Pepe, Francesco;
Troncone, Giancarlo;
Malapelle, Umberto;
Carosi, Mariantonia;
Casini, Beatrice;
Melucci, Elisa;
Fassan, Matteo;
Toffolatti, Luisa;
Guerini-Rocco, Elena;
Conversano, Federica;
Rappa, Alessandra;
Tommasi, Stefania

Publication type:

Article

Effects of DHA Oral Supplementation on Plasma Resolvin D1 and D2 Levels in Naïve Breast Cancer Patients.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1694, doi. 10.3390/cancers17101694

By:

Molfino, Alessio;
Imbimbo, Giovanni;
Salerno, Gerardo;
Lionetto, Luana;
De Luca, Alessandro;
Simmaco, Maurizio;
Gallicchio, Carmen;
Picconi, Orietta;
Amabile, Maria Ida;
Muscaritoli, Maurizio

Publication type:

Article

Survival Outcomes Associated with the Location of BRCA Mutations in Ovarian Cancer: A Systematic Review and Meta-Analysis.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1661, doi. 10.3390/cancers17101661

By:

Kim, Ji Hyun;
Yoon, Hyung Joon;
Ha, Hyeong In;
Kim, Eun Taeg;
Kim, Dongkyu Eugene;
Kim, Sangeon;
Bae, Jae Kyung;
Lim, Myong Cheol

Publication type:

Article

Personalizing Neoadjuvant Chemotherapy: The Impact of BRCA Variants on Pathologic Complete Response in Luminal B Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1619, doi. 10.3390/cancers17101619

By:

Di Leone, Alba;
Franco, Antonio;
Castagnetta, Virginia;
Silenzi, Marta;
Accetta, Cristina;
Carnassale, Beatrice;
D'Archi, Sabatino;
De Lauretis, Flavia;
Di Guglielmo, Enrico;
Gagliardi, Federica;
Magno, Stefano;
Moschella, Francesca;
Natale, Maria;
Sanchez, Alejandro Martin;
Scardina, Lorenzo;
Masetti, Riccardo;
Franceschini, Gianluca

Publication type:

Article

Germinal mutations among patients with breast cancer in Colombia: is BRCA3 coming?

Published in:

Ecancermedicalscience, 2025, v. 19, n. 1824-1915, p. 1, doi. 10.3332/ecancer.2025.1859

By:

Rodríguez Rojas, Lisa Ximena;
Doza Martínez, Liliana;
Olave Rodríguez, Jorge Andrés;
Murillo Rusynke, Sandra Eliana;
Pérez Castellano, Paola Andrea;
Bolaños Beltrán, David Alexander;
Ortiz Rojas, Helen Johana;
Nastasi Catanese, José Antonio

Publication type:

Article

Treatment Patterns, Clinical Outcomes and Quality of Life in BRCA1/2-Associated Breast Cancer Patients: A Retrospective Analysis.

Published in:

Current Oncology, 2025, v. 32, n. 5, p. 269, doi. 10.3390/curroncol32050269

By:

Parger, Anna-Maria;
Gebhart, Paulina;
Muhr, Daniela;
Singer, Christian F.;
Tan, Yen Y.

Publication type:

Article

Different Mechanisms in Doxorubicin-Induced Neurotoxicity: Impact of BRCA Mutations.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4736, doi. 10.3390/ijms26104736

By:

Bhatt, Kriti S.;
Singh, Aman;
Marwaha, Gursharan S.;
Ravendranathan, Naresh;
Sandhu, Inderbir S.;
Kim, Kristen;
Singh, Eesha;
Frisbee, Jefferson C.;
Singh, Krishna K.

Publication type:

Article

Ovarian Cancer—Epidemiology, Classification, Pathogenesis, Treatment, and Estrogen Receptors' Molecular Backgrounds.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4611, doi. 10.3390/ijms26104611

By:

Smolarz, Beata;
Biernacka, Karolina;
Łukasiewicz, Honorata;
Samulak, Dariusz;
Piekarska, Ewa;
Romanowicz, Hanna;
Makowska, Marianna

Publication type:

Article

Gut microbiome associated with PARP inhibitor efficacy in patients with ovarian cancer.

Published in:

Journal of Gynecologic Oncology, 2025, v. 36, n. 3, p. 1, doi. 10.3802/jgo.2025.36.e38

By:

Okazawa-Sakai, Mika;
Sakai, Shunsuke A.;
Ichinosuke Hyodo;
Satoshi Horasawa;
Kentaro Sawada;
Takao Fujisawa;
Yasuko Yamamoto;
Shogen Boku;
Yoh Hayasaki;
Masanori Isobe;
Daisuke Shintani;
Kosei Hasegawa;
Tomomi Egawa-Takata;
Kimihiko Ito;
Kei Ihira;
Hidemichi Watari;
Kazuhiro Takehara;
Hiroshi Yagi;
Kiyoko Kato;
Tatsuyuki Chiyoda

Publication type:

Article

Proline‐ and Serine‐Rich Coiled‐Coil 1 Predicts an Unfavorable Prognosis and Exhibits Oncogenic Activities in Breast Cancer.

Published in:

IUBMB Life, 2025, v. 77, n. 5, p. 1, doi. 10.1002/iub.70019

By:

Jin, Xin;
Zhao, Qingqing;
Hao, Xiaowen;
Shi, Peicong;
Wang, Yan;
Wang, Pei

Publication type:

Article

Screening for BRCA1 large genomic rearrangements in female Egyptian hereditary breast cancer patients.

Published in:

Eastern Mediterranean Health Journal, 2013, v. 19, n. 3, p. 255, doi. 10.26719/2013.19.3.255

By:

Hagag, E.;
Shwaireb, M.;
Coffa, J.;
El Wakil, A.

Publication type:

Article

Fertility Preservation and Breast Cancer: A Complex Problem.

Published in:

Oncology (08909091), 2013, v. 27, n. 6, p. 1

By:

Munster, Pamela N.

Publication type:

Article

Fertility Preservation in Women With Breast Cancer: Challenges and Opportunities.

Published in:

2013

By:

Woodard, Terri L.;
Litton, Jennifer K.

Publication type:

Opinion

Genetic Testing in Gastrointestinal Cancers: A Case-Based Approach.

Published in:

Oncology (08909091), 2012, v. 26, n. 5, p. 433

By:

SCHRADER, KASMINTAN;
OFFIT, KENNETH;
STADLER, ZSOFIA K.

Publication type:

Article

Study Finds Different Treatment Responses Between BRCA2- and BRCA1-Mutated Ovarian Cancers.

Published in:: Oncology (08909091), 2011, v. 25, n. 12, p. 1237
Publication type:: Article

Screening Identifies Mechanisms of Drug Resistance to PI3K Inhibitors.

Published in:: Oncology (08909091), 2011, v. 25, n. 11, p. 1
Publication type:: Article

PARP Inhibitors in Breast Cancer: BRCA and Beyond.

Published in:

Oncology (08909091), 2011, v. 25, n. 11, p. 1

By:

Rios, Jorge;
Puhalla, Shannon

Publication type:

Article

PARP Inhibitors and Their Evolving Role in Breast Cancer.

Published in:

2011

By:

Roop, Ryan P.;
Ma, Cynthia X.;
Ellis, Matthew J. C.

Publication type:

Opinion

PARP Inhibitors: the Story is Still Unfolding.

Published in:

2011

By:

Tripathy, Debu

Publication type:

Opinion

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 11, p. 962, doi. 10.1038/nsmb.2899

By:

Shahid, Taha;
Soroka, Joanna;
Kong, Eric H;
Malivert, Laurent;
McIlwraith, Michael J;
Pape, Tillmann;
West, Stephen C;
Zhang, Xiaodong

Publication type:

Article

A mediator methylation mystery: JMJD1C demethylates MDC1 to regulate DNA repair.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1346, doi. 10.1038/nsmb.2729

By:

Lu, Jian;
Matunis, Michael J

Publication type:

Article

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 10, p. 1191, doi. 10.1038/nsmb.2666

By:

Jeyasekharan, Anand D;
Liu, Yang;
Hattori, Hiroyoshi;
Pisupati, Venkat;
Jonsdottir, Asta Bjork;
Rajendra, Eeson;
Lee, Miyoung;
Sundaramoorthy, Elayanambi;
Schlachter, Simon;
Kaminski, Clemens F;
Ofir-Rosenfeld, Yaara;
Sato, Ko;
Savill, Jane;
Ayoub, Nabieh;
Venkitaraman, Ashok R

Publication type:

Article

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 916, doi. 10.1038/nsmb.2353

By:

Cui, Gaofeng;
Park, Sungman;
Badeaux, Aimee I;
Kim, Donghwa;
Lee, Joseph;
Thompson, James R;
Yan, Fei;
Kaneko, Satoshi;
Yuan, Zengqiang;
Botuyan, Maria Victoria;
Bedford, Mark T;
Cheng, Jin Q;
Mer, Georges

Publication type:

Article

Unraveling the mechanism of BRCA2 in homologous recombination.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 7, p. 748, doi. 10.1038/nsmb.2096

By:

Holloman, William K.

Publication type:

Article

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1263, doi. 10.1038/nsmb.1905

By:

Thorslund, Tina;
McIlwraith, Michael J.;
Compton, Sarah A.;
Lekomtsev, Sergey;
Petronczki, Mark;
Griffith, Jack D.;
West, Stephen C.

Publication type:

Article

Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1247, doi. 10.1038/nsmb.1915

By:

Buisson, Rémi;
Dion-Côté, Anne-Marie;
Coulombe, Yan;
Launay, Hélène;
Hong Cai;
Stasiak, Alicja Z.;
Stasiak, Andrzej;
Bing Xia;
Masson, Jean-Yves

Publication type:

Article

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1260, doi. 10.1038/nsmb.1904

By:

Jie Liu;
Doty, Tammy;
Gibson, Bryan;
Heyer, Wolf-Dietrich

Publication type:

Article

New partners for BRCA1.

Published in:: 2007
Publication type:: Editorial

E2–BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 10, p. 941, doi. 10.1038/nsmb1295

By:

Christensen, Devin E.;
Brzovic, Peter S.;
Klevit, Rachel E.

Publication type:

Article

Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 6, p. 1, doi. 10.1038/nsmb1251

By:

Davies, Owen Richard;
Pellegrini, Luca

Publication type:

Article

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 6, p. 468, doi. 10.1038/nsmb1245

By:

Esashi, Fumiko;
Galkin, Vitold E.;
Xiong Yu;
Egelman, Edward H.;
West, Stephen C.

Publication type:

Article

Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation.

Published in:

2018

By:

Müller, Dirk;
Danner, Marion;
Rhiem, Kerstin;
Stollenwerk, Björn;
Engel, Christoph;
Rasche, Linda;
Borsi, Lisa;
Schmutzler, Rita;
Stock, Stephanie

Publication type:

journal article

The cost-utility of magnetic resonance imaging for breast cancer in BRCA1 mutation carriers aged 30-49.

Published in:

2007

By:

Norman, Richard P. A.;
Evans, D. Gareth;
Easton, Douglas F.;
Young, Kenneth C.

Publication type:

journal article

BRCA 1–2 Incidence in Synchronous and Metachronous Breast Cancer: a Tertiary Center Study.

Published in:

Indian Journal of Surgery, 2023, v. 85, n. 1, p. 25, doi. 10.1007/s12262-022-03335-1

By:

Dağ, Ahmet;
Arslan, Bilal;
Güler, Erkan;
Mermer, Serdar

Publication type:

Article