Title: Synthesis and Antimicrobial Evaluation of Some Thiazole Derivatives.
Authors: Bhuiyan, M. M. H.; Rahman, A. F. M. H.
Abstract: Reaction of 2-amino-4-phenylthiazole with various aromatic aldehydes afforded 2- arylideneamino-4-phenylthiazoles. On the other hand treatment of 2-amino-4- phenylthiazole with several acyl halides furnished N-(thiazol-2-yl)-amides. The synthesized compounds have been screened for their antimicrobial activity against Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Shigella dysenteriae, Salmonella typhi, Pseudomonous sp. bacteria and Aspergillus niger, Penicillium notatum, Aspergillus funiculosus, Collectrichum corchori Ikata (Yoshida) and Curvularia lunata fungi respectively. Some of the synthesized compounds exhibited pronounced antimicrobial activities.
Subjects: BIOSYNTHESIS; ANTI-infective agents; THIAZOLES; ALDEHYDES; ACYL halides; AMIDES
Publication: Journal of Scientific Research, 2011, Vol 3, Issue 1, p111
ISSN: 2070-0237
Publication type: Academic Journal
DOI: 10.3329/jsr.v3i1.5419

Synthesis and Antimicrobial Evaluation of Some Thiazole Derivatives.

Bhuiyan, M. M. H.; Rahman, A. F. M. H.