Title: Hepatoprotective potential of Convolvulus arvensis against paracetamol-induced hepatotoxicity.
Authors: Ali, Mohsin; Qadir, M. Imran; Saleem, Mohammad; Janbaz, Khalid Hussain; Gul, Humaira; Hussain, Liaqat; Ahmad, Bashir
Abstract: Convolvulus arvensis is traditionally used as laxative. Its decoction is used in cough, flu, jaundice and in skin diseases. It is also used to treat the painful joints, inflammation and swelling. The current study was conducted to determine its hepatoprotective activity. The results showed that extract of C. arvensis (200 mg/kg and 500 mg/kg) produced significant (p<0.05) decrease in paracetamol induced increased levels of liver enzymes and total bilirubin. Histopathological investigation and detection of active constituent, qurecetin by HPLC also supported the results. So the current study showed that ethanolic extract of C. arvensis possess hepatoprotective activity.
Subjects: FIELD bindweed; ACETAMINOPHEN; HEPATOTOXICOLOGY; LAXATIVES; COUGH treatment; INFLUENZA treatment; JAUNDICE treatment; SKIN disease treatment; THERAPEUTICS
Publication: Bangladesh Journal of Pharmacology, 2013, Vol 8, Issue 3, p300
ISSN: 1991-007X
Publication type: Academic Journal
DOI: 10.3329/bjp.v8i3.15165

Hepatoprotective potential of Convolvulus arvensis against paracetamol-induced hepatotoxicity.

Ali, Mohsin; Qadir, M. Imran; Saleem, Mohammad; Janbaz, Khalid Hussain; Gul, Humaira; Hussain, Liaqat; Ahmad, Bashir