Heterocyclic compounds occur widely in nature and in a variety of non-naturally compounds, large number of heterocyclic compounds are essential to life such as alkaloids, antibiotics, essential amino acids, the vitamins, hemoglobin, hormones, a large number of synthetic drugs and dyes. Thiadiazole are very interesting compounds due to their important applications in many pharmaceutical biological and analytical fields.This review showed the optical, electrochemical properties, electrical conductivity and magnetic susceptibility for thiadiazole compounds .