Works matching DE "ANTINEOPLASTIC agent synthesis"

Results: 137

High-value alcohols and higher-oxidation-state compounds by catalytic Z-selective cross-metathesis.

Published in:

Nature, 2015, v. 517, n. 7533, p. 181, doi. 10.1038/nature14061

By:

Koh, Ming Joo;
Khan, R. Kashif M.;
Torker, Sebastian;
Yu, Miao;
Mikus, Malte S.;
Hoveyda, Amir H.

Publication type:

Article

A diaryl-linked [Pd 2 L 4 ] metallosupramolecular architecture: synthesis, structures and cisplatin binding studies.

Published in:

Supramolecular Chemistry, 2015, v. 27, n. 11/12, p. 734, doi. 10.1080/10610278.2015.1063633

By:

Kim, Tae Y.;
Lucas, Nigel T.;
Crowley, James D.

Publication type:

Article

Synthesis and study of antitumor activity of tetraethyl 2-(2′,2′,6′,6′-Tetramethylpiperidin-4′-ylamino)ethylidene-1,1-bisphosphonate.

Published in:

Doklady Chemistry, 2014, v. 457, n. 1, p. 137, doi. 10.1134/S0012500814070064

By:

Grigor'ev, I.;
Morozov, D.;
Svyatchenko, V.;
Kiselev, N.;
Loktev, V.;
Luk'yanets, E.;
Vorozhtsov, G.

Publication type:

Article

SYNTHESIS AND ANTI-CANCER ACTIVITY OF NOVEL 3-ARYL THIOPHENE-2-CARBALDEHYDES AND THEIR ARYL/HETEROARYL CHALCONE DERIVATIVES.

Published in:

Rasayan Journal of Chemistry, 2016, v. 9, n. 1, p. 31

By:

Venkataramireddy, V.;
Shankaraiah, M.;
Rao, A. Tejeswara;
Kalyani, Ch.;
Narasu, M. Lakshmi;
Varala, Ravi;
Jayashree, A.

Publication type:

Article

Structure elucidation of 3-[1-(6-methoxy-2-naphtyl)ethyl]-6-(2,4-dichlorophenyl)-7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine, C23H18Cl2N4OS from synchrotron X-ray powder diffraction.

Published in:

Powder Diffraction, 2017, v. 32, n. 4, p. 271, doi. 10.1017/S0885715617001099

By:

Gündoğdu, Gülsüm;
Aytaç, Sevim Peri;
Müller, Melanie;
Tozkoparan, Birsen;
Kaynak, Filiz Betül

Publication type:

Article

Preparation of Diaminedicarboxyplatinum (II) Functionalized Single-Wall Carbon Nanotube via Bingel Reaction as a Novel Cytotoxic Agent.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, n. 4, p. 753

By:

Irannejad, Saeed;
Amini, Mohsen;
Modanlookordi, Mona;
Shokrzadeh, Mohammad;
Irannejad, Hamid

Publication type:

Article

Design and Synthesis of Pyrrolo[2,1-a]Isoquinoline-Based Derivatives as New Cytotoxic Agents.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, n. 4, p. 743

By:

Kakhki, Samaneh;
Shahosseini, Soraya;
Zarghi, Afshin

Publication type:

Article

Assessment of the Cytotoxic Effect of a Series of 1,4-Dihydropyridine Derivatives Against Human Cancer Cells.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, n. 3, p. 413

By:

Razzaghi-Asla, Nima;
Miri, Ramin;
Firuzi, Omidreza

Publication type:

Article

Inclusion Complex of Podophyllotoxin with γ-Cyclodextrin: Preparation, Characterization, Anticancer Activity, Water-Solubility and Toxicity.

Published in:

Chinese Journal of Chemistry, 2016, v. 34, n. 4, p. 425, doi. 10.1002/cjoc.201500692

By:

Guo, Yafei;
Zhang, Yushun;
Li, Jiuling;
Zhao, Fen;
Liu, Yang;
Su, Min;
Jiang, Yubo;
Liu, Yuqi;
Zhang, Jihong;
Yang, Bo;
Yang, Rui

Publication type:

Article

Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 3, p. 648, doi. 10.3390/ijms18030648

By:

Woods, Laura M.;
Arico, Joseph W.;
Frein, Jeffrey D.;
Sackett, Dan L.;
Taylor, Richard E.

Publication type:

Article

D-Amino Acid Position Influences the Anticancer Activity of Galaxamide Analogs: An Apoptotic Mechanism Study.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 3, p. 544, doi. 10.3390/ijms18030544

By:

Bai, Defa;
Siming Yu;
Shenghui Zhong;
Bingxin Zhao;
Shaoling Qiu;
Jianwei Chen;
Lunagariya, Jignesh;
Xiaojian Liao;
Shihai Xu

Publication type:

Article

A Series of New Ligustrazine-Triterpenes Derivatives as Anti-Tumor Agents: Design, Synthesis, and Biological Evaluation.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 9, p. 21035, doi. 10.3390/ijms160921035

By:

Bing Xu;
Fuhao Chu;
Yuzhong Zhang;
Xiaobo Wang;
Qiang Li;
Wei Liu;
Xin Xu;
Yanyi Xing;
Jing Chen;
Penglong Wang;
Haimin Lei

Publication type:

Article

Efficient Synthesis of a Maghemite/Gold Hybrid Nanoparticle System as a Magnetic Carrier for the Transport of Platinum-Based Metallotherapeutics.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 1, p. 2034, doi. 10.3390/ijms16012034

By:

Štarha, Pavel;
Smola, David;
Tuček, Jiří;
Trávníček, Zdeněk

Publication type:

Article

Synthesis, Docking and Biological Activities of Novel Hybrids Celecoxib and Anthraquinone Analogs as Potent Cytotoxic Agents.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 12, p. 22580, doi. 10.3390/ijms151222580

By:

Almutairi, Maha S.;
Hegazy, Gehan H.;
Haiba, Mogedda E.;
Ali, Hamed I.;
Khalifa, Nagy M.;
Soliman, Abd El-mohsen M.

Publication type:

Article

In Vitro Evaluation of Zn-Norfloxacin Complex as a Potent Cytotoxic and Antibacterial Agent, Proposed Model for DNA Binding.

Published in:

Applied Biochemistry & Biotechnology, 2013, v. 170, n. 4, p. 988, doi. 10.1007/s12010-013-0255-6

By:

Ahmadi, F.;
Saberkari, M.;
Abiri, R.;
Motlagh, H.;
Saberkari, H.

Publication type:

Article

Iridium-Catalyzed Enantioselective Allylic Substitution of Unstabilized Enolates Derived from α,β-Unsaturated Ketones.

Published in:

Angewandte Chemie, 2014, v. 126, n. 33, p. 8835, doi. 10.1002/ange.201403844

By:

Chen, Ming;
Hartwig, John F.

Publication type:

Article

Total Synthesis and Biological Evaluation of Jerantinine E.

Published in:

Angewandte Chemie, 2013, v. 125, n. 50, p. 13615, doi. 10.1002/ange.201305533

By:

Frei, Reto;
Staedler, Davide;
Raja, Aruna;
Franke, Raimo;
Sasse, Florenz;
Gerber ‐ Lemaire, Sandrine;
Waser, Jérôme

Publication type:

Article

Double crosslinked chitosan and gelatin submicronic capsules entrapping aminoacid derivatives with potential antitumoral activity.

Published in:

Journal of Materials Science, 2012, v. 47, n. 23, p. 8223, doi. 10.1007/s10853-012-6719-1

By:

Moise, Mihaela;
Şunel, Valeriu;
Holban, Mihaela;
Popa, Marcel;
Desbrieres, Jacques;
Peptu, Cristian;
Lionte, Cătălina

Publication type:

Article

A Convenient and Easy Purification Approach to High-Yield Synthesis of Gefitinib as an Anticancer Agent from Isovaniline.

Published in:

Pharmaceutical Chemistry Journal, 2014, v. 48, n. 8, p. 520, doi. 10.1007/s11094-014-1141-4

By:

Chandrasekhar, M.;
Srinivasulu, D.;
Seshaiah, K.;
Kumar, Neeraj

Publication type:

Article

Synthesis and antitumor activity of 2- N- and 3- S-substituted 5-[2-(4-)benzyloxyphenyl]-1,2,4-triazoles and acylhydrazides.

Published in:

Pharmaceutical Chemistry Journal, 2012, v. 46, n. 9, p. 531, doi. 10.1007/s11094-012-0840-y

By:

Grigoryan, L.;
Kaldrikyan, M.;
Melik-Ogandzhanyan, R.;
Arsenyan, F.

Publication type:

Article

Algorithm of Molecular and Biological Assessment of the Mechanisms of Sensitivity to Drug Toxicity by the Example of Cyclophosphamide.

Published in:

Bulletin of Experimental Biology & Medicine, 2018, v. 164, n. 3, p. 324, doi. 10.1007/s10517-018-3982-4

By:

Telegin, L.;
Sarmanaev, S.;
Devichenskii, V.;
Tutelyan, V.

Publication type:

Article

Cyclopropanol intermediates in the synthesis of the C-C fragment of laulimalides.

Published in:

Russian Journal of Organic Chemistry, 2016, v. 52, n. 3, p. 355, doi. 10.1134/S1070428016030118

By:

Mineeva, I.

Publication type:

Article

Aryl sulfonate based anticancer alkylating agents.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2018, v. 31, p. 1081

By:

Sheikh, Hamdullah Khadim;
Arshad, Tanzila;
Kanwal, Ghazala

Publication type:

Article

Evaluation of cytotoxic and antiviral activities of aqueous leaves extracts of different plants against foot and mouth disease virus infection in farming animals.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2017, v. 30, n. 6, p. 2167

By:

Younus, Ishrat;
Ashraf, Muhammad;
Fatima, Anab;
Altaf, Imran;
Javeed, Aqeel

Publication type:

Article

Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy.

Published in:

British Journal of Cancer, 2015, v. 112, n. 5, p. 832, doi. 10.1038/bjc.2015.17

By:

Tan, Q;
Joshua, A M;
Saggar, J K;
Yu, M;
Wang, M;
Kanga, N;
Zhang, J Y;
Chen, X;
Wouters, B G;
Tannock, I F

Publication type:

Article

MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

Published in:

British Journal of Cancer, 2015, v. 112, n. 5, p. 883, doi. 10.1038/bjc.2015.27

By:

Walter, R F H;
Mairinger, F D;
Ting, S;
Vollbrecht, C;
Mairinger, T;
Theegarten, D;
Christoph, D C;
Schmid, K W;
Wohlschlaeger, J

Publication type:

Article

Synthesis, DNA Interactions and Anticancer Evaluation of Novel Diamidine Derivatives of 3,4-Ethylenedioxythiophene.

Published in:

Croatica Chemica Acta, 2012, v. 85, n. 4, p. 457, doi. 10.5562/cca2141

By:

Stolić, Ivana;
Avdičević, Monika;
Bregović, Nikola;
Piantanida, Ivo;
Glavaš-Obrovac, Ljubica;
Bajić, Miroslav

Publication type:

Article

The influence of the time-of-day administration of the drug on the pharmacokinetics of sunitinib in rabbits.

Published in:

European Review for Medical & Pharmacological Sciences, 2014, v. 18, n. 16, p. 2393

By:

SZAŁEK, E.;
KARBOWNIK, A.;
SOBAŃSKA, K.;
POŁOM, W.;
GRABOWSKI, T.;
WOLC, A.;
MATUSZEWSKI, M.;
GRZEŚKOWIAK, E.

Publication type:

Article

Ribonucleolytic activity of mycoplasmas.

Published in:

Microbiology (00262617), 2014, v. 83, n. 3, p. 247, doi. 10.1134/S0026261714030072

By:

Ilinskaya, O.;
Sokurenko, Yu.;
Ul'yanova, V.;
Vershinina, V.;
Zelenikhin, P.;
Kolpakov, A.;
Medvedeva, E.;
Baranova, N.;
Davydova, M.;
Muzykantov, A.;
Chernova, O.;
Chernov, V.

Publication type:

Article

Total Synthesis, Configuration, and Biological Evaluation of Anguinomycin C.

Published in:

Asian Journal of Control, 2013, v. 15, n. 6, p. 8707, doi. 10.1002/anie.200703134

By:

Bonazzi, Simone;
Güttinger, Stephan;
Zemp, Ivo;
Kutay, Ulrike;
Gademann, Karl

Publication type:

Article

Antitumor and Antimicrobial Activity of Some Cyclic Tetrapeptides and Tripeptides Derived from Marine Bacteria.

Published in:

Marine Drugs, 2015, v. 13, n. 5, p. 3029, doi. 10.3390/md13053029

By:

Chakraborty, Subrata;
Dar-Fu Tai;
Yi-Chun Lin;
Tzyy-Wen Chiou

Publication type:

Article

Activation of Dormant Secondary Metabolite Production by Introducing Neomycin Resistance into the Deep-Sea Fungus, Aspergillus versicolor ZBY-3.

Published in:

Marine Drugs, 2014, v. 12, n. 8, p. 4326, doi. 10.3390/md12084326

By:

Yuan Dong;
Cheng-Bin Cui;
Chang-Wei Li;
Wei Hua;
Chang-Jing Wu;
Tian-Jiao Zhu;
Qian-Qun Gu

Publication type:

Article

Synthesis and Antitumor Activities of Derivatives of the Marine Mangrove Fungal Metabolite Deoxybostrycin.

Published in:

Marine Drugs, 2012, v. 10, n. 12, p. 2715, doi. 10.3390/md10122715

By:

Hong Chen;
Xun Zhu;
Li-Li Zhong;
Bing Yang;
Jia Li;
Jue-Heng Wu;
Sheng-Ping Chen;
Yong-Cheng Lin;
Yuhua Long;
Zhi-Gang She

Publication type:

Article

Correction to: Lipophilic gold(I) complexes with 1,3,4-oxadiazol-2-thione or 1,3-thiazolidine-2-thione moieties: synthesis and their cytotoxic and antimicrobial activities.

Published in:

2017

By:

Almeida, Angelina;
Oliveira, Bruno;
Castro, Pedro;
Mendonça, Camille;
Furtado, Ricardo;
Nicolella, Heloiza;
Silva, Vânia;
Diniz, Cláudio;
Tavares, Denise;
Silva, Heveline;
Almeida, Mauro

Publication type:

Erratum

Anti-proliferative effect of Fe(III) complexed with 1-(2-hydroxy-3-methoxybenzaldehyde)-4-aminosalicylhydrazone in HepG2 cells.

Published in:

BioMetals, 2015, v. 28, n. 4, p. 669, doi. 10.1007/s10534-015-9852-x

By:

Fukushima, Takeshi;
Taniguchi, Erina;
Yamada, Hiroshi;
Kato, Kiyomasa;
Shimizu, Ayako;
Nishiguchi, Yoshikazu;
Onozato, Mayu;
Ichiba, Hideaki;
Azuma, Yutaro

Publication type:

Article

(E)-3-(Aryl(arylamino)methylene)indolin-2-one derivatives: an efficient synthetic approach and evaluation of their cancer inhibitory activity.

Published in:

Journal of Chemical Research, 2018, v. 42, n. 1, p. 44, doi. 10.3184/174751918X15166485941737

By:

Hongwu Jiang;
Zhiyuan Feng;
Taiping Chena;
Zicheng Li;
Wencai Huang;
Youfu Luo;
Yinglan Zhao

Publication type:

Article

A convenient synthesis of gimeracil.

Published in:

Journal of Chemical Research, 2018, v. 42, n. 1, p. 33, doi. 10.3184/174751918X15166150010920

By:

Xiao-lin Li;
Hao-ting Zhu;
Li Zhan;
Ting Liu;
Guang Cheng;
Ning Liu;
Shan-bao Yuc;
Hui Li;
Yu Luo;
Fan Yang;
Jie Tang

Publication type:

Article

A novel and efficient synthesis of anti-cancer agent, mereletinib.

Published in:

Journal of Chemical Research, 2015, v. 39, n. 6, p. 318, doi. 10.3184/174751915X14320297505570

By:

Liu, Haidong;
Lv, Yongfeng;
Li, Yuan;
Cai, Jin;
Chen, Junqing;
Qin, Yu;
Ji, Min

Publication type:

Article

The newly synthesized anticancer drug HUHS1015 is useful for treatment of human gastric cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 527, doi. 10.1007/s00280-014-2661-z

By:

Kaku, Yoshiko;
Tsuchiya, Ayako;
Kanno, Takeshi;
Nakao, Shuhei;
Shimizu, Tadashi;
Tanaka, Akito;
Nishizaki, Tomoyuki

Publication type:

Article

Novel Synthesis, spectral, characterization of 4,5- diphenyl-1-((tetrahydrofuran-2-yl)methyl)-2-(3,4,5-trichlorophenyl)-1H-imidazole and its applications of molecular docking, anticancer activity.

Published in:

World News of Natural Sciences (WNOFNS), 2020, v. 30, p. 214

By:

Dhineshkumar, E.;
doss, M. Arockia;
Uma, D.

Publication type:

Article

Macrocyclic complexes: synthesis, characterization, antitumor and DNA binding studies.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2018, v. 37, n. 9, p. 498, doi. 10.1080/15257770.2018.1498515

By:

Lamani, Devappa S.;
Badiger, S. G.;
Venugopala Reddy, K. R.;
Bhojya Naik, H. S.

Publication type:

Article

Rapid Synthesis of 3-(difluoromethyl)-1-methyl-pyrazole carboxamide derivatives and their Characterization, anticancer and antifungal activities.

Published in:

Chemistry & Biology Interface, 2018, v. 8, n. 2, p. 115

By:

S., Adinarayana;
Choudhary, Prakash C.

Publication type:

Article

Synthesis and anticancer / antibacterial activity of compounds containing thiophene ring linked to a chalcone derivatives.

Published in:

Chemistry & Biology Interface, 2018, v. 8, n. 2, p. 94

By:

D., Chandra Sekhar;
A., Tejeswara Rao;
D. V., Venkata Rao;
U., Lav Kumar;
Jha, Anjali

Publication type:

Article

Synthesis of new 2-substituted-10-phenylsulfonylphenothiazine conjugates and evaluation as anticancer agents by investigating their off-target mechanism.

Published in:

Chemistry & Biology Interface, 2018, v. 8, n. 2, p. 84

By:

Das, Tonmoy Chitta;
Quadri, Syed Aziz;
Jadav, Shivaji Laxman;
Farooqui, Mazahar

Publication type:

Article

Gelatin-Assisted Synthesis of Vaterite Nanoparticles with Higher Surface Area and Porosity as Anticancer Drug Containers In Vitro.

Published in:

ChemPlusChem, 2016, v. 81, n. 2, p. 194, doi. 10.1002/cplu.201500515

By:

Wang, Anhe;
Yang, Yang;
Zhang, Xiaoming;
Liu, Xingcen;
Cui, Wei;
Li, Junbai

Publication type:

Article

Synthesis and anticancer activity of novel quinazolinone and benzamide derivatives.

Published in:

Research on Chemical Intermediates, 2018, v. 44, n. 4, p. 2545, doi. 10.1007/s11164-017-3245-4

By:

El-Hashash, Maher Abd El-Aziz Mahmoud;
Salem, Marwa Sayed;
Al-Mabrook, Selima Ali Mohamed

Publication type:

Article

Synthesis and anticancer activities of 1,4-phenylene-bis- N-acetyl- and N-phenylpyrazoline derivatives.

Published in:

Research on Chemical Intermediates, 2017, v. 43, n. 3, p. 1277, doi. 10.1007/s11164-016-2697-2

By:

Gürdere, Meliha;
Gümüş, Onur;
Yaglioglu, Ayse;
Budak, Yakup;
Ceylan, Mustafa

Publication type:

Article

Synthesis, crystal structure and antitumor activity of a dinuclear calcium complex based on 1,5-naphthalenedisulfonate and 2,2′-bipyridine ligands.

Published in:

Research on Chemical Intermediates, 2015, v. 41, n. 7, p. 4339, doi. 10.1007/s11164-014-1533-9

By:

Tai, Xi-Shi;
Zhang, Yan-Ping;
Zhao, Wen-Hua

Publication type:

Article

Synthesis of some new pyrimidine derivatives and evaluation of their anticancer and antibacterial activities.

Published in:

Research on Chemical Intermediates, 2013, v. 39, n. 3, p. 821, doi. 10.1007/s11164-012-0597-7

By:

Fathalla, Omar;
Mohamed, Neama;
El-Serwy, Walaa;
AbdelHamid, Hala;
Abd El-Moez, Sherein;
Soliman, Abdel-mohsen

Publication type:

Article

Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates.

Published in:

Pharmaceutical Research, 2015, v. 32, n. 5, p. 1676, doi. 10.1007/s11095-014-1566-1

By:

Magoulas, George;
Bantzi, Marina;
Messari, Danai;
Voulgari, Efstathia;
Gialeli, Chrisostomi;
Barbouri, Despoina;
Giannis, Athanassios;
Karamanos, Nikos;
Papaioannou, Dionissios;
Avgoustakis, Konstantinos

Publication type:

Article