Title: The design and synthesis of acrylato and imino derivatives of calix[4]arene for applications in static and dynamic combinatorial libraries.
Authors: Le-Gresley, Adam; Kuhnert, Nikolai
Abstract: The synthesis of novel calix[4]arene tetra-acrylates and the potential use of macrocyclic platforms in the development of static and dynamic combinatorial libraries (DCL) using reversible imine formationare described. Using such a macrocyclic platform in DCL formation results in a large number of library members while keeping the number of building blocks in the library to a minimum number.
Subjects: CHEMICAL research; MOLECULAR self-assembly; SUPRAMOLECULAR chemistry; CALIXARENES; AMINO acids; BARBITURATES; BIOTIN; STEREOISOMERS; THERMODYNAMIC equilibrium; ANISOTROPY
Publication: Journal of Chemical Research, 2010, Vol 34, Issue 2, p61
ISSN: 1747-5198
Publication type: Academic Journal
DOI: 10.3184/030823410X12627159407690

The design and synthesis of acrylato and imino derivatives of calix[4]arene for applications in static and dynamic combinatorial libraries.

Le-Gresley, Adam; Kuhnert, Nikolai